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3601
Inflammatory Bowel Disease: Progress Towards a Gene
Published 2000-01-01“…The pathogenesis of ulcerative colitis (UC) and Crohn’s disease (CD) is still unknown, but the importance of genetic susceptibility has been clearly shown by epidemiological data from family and twin studies. …”
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3602
Phenotypic and Cytogenetic Characterization of Mesenchymal Stromal Cells in De Novo Myelodysplastic Syndromes
Published 2016-01-01“…Further, the occurrence of genetic abnormalities in BM-MSCs in MDS could be considered as an autonomous event from that of their hematopoietic counterparts.…”
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3603
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3604
The study of agronomical traits determining productivity of Triticum aestivum/Triticum timopheevii introgression lines with resistance to fungal diseases
Published 2016-08-01“…The gene pool of wild and cultivated wheat relatives is often used for widening the wheat genetic diversity of resistance genes. However, alien genetic material introgressed into the wheat genome can contain genetic factors negatively affecting agronomically important traits. …”
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3605
Osteoblast-Specific Overexpression of Nucleolar Protein NO66/RIOX1 in Mouse Embryos Leads to Osteoporosis in Adult Mice
Published 2023-01-01“…In previous study, we showed that nucleolar protein 66 (NO66) is a chromatin modifier and negatively regulates Osterix activity as well as mesenchymal progenitor differentiation. Genetic ablation of the NO66 (RIOX1) gene in cells of the Prx1-expressing mesenchymal lineage leads to acceleration of osteochondrogenic differentiation and a larger skeleton in adult mice, whereas mesenchyme-specific overexpression of NO66 inhibits osteochondrogenesis resulting in dwarfism and osteopenia. …”
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The bristle pattern development in Drosophila melanogaster: the prepattern and achaete-scute genes
Published 2019-01-01“…The structural organization and principles of operation of the hierarchical molecular genetic system enabling the local expression of ASC genes and the resulting formation of ordered bristle pattern are described.…”
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3609
Carcinogenic and anticancer activities of microbiota-derived secondary bile acids
Published 2025-01-01“…The article also discusses the complex interplay between SBAs and the host’s genetic and environmental factors, highlighting potential therapeutic implications and the need for targeted strategies to mitigate risks while harnessing beneficial effects. …”
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3610
Antinociceptive, Anti-Inflammatory, and Antipyretic Activity of Mangrove Plants: A Mini Review
Published 2012-01-01Get full text
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3611
The domestication and the brain: forty years after
Published 2017-07-01“…This hypothesis was confirmed at the Institute of Cytology and Genetics, Novosibirsk, by unique long-lasting selection of silver foxes, Norway rats and American minks for nonaggressive behavior towards man. …”
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3612
Nonapoptotic caspase-3 guides C1q-dependent synaptic phagocytosis by microglia
Published 2025-01-01“…This increased susceptibility is reversed by genetic depletion of microglial complement receptors. …”
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3613
Epigenetic regulation of bone remodeling and its role in the pathogenesis of primary osteoporosis
Published 2023-07-01“…The number of identified molecular genetic markers for osteoporosis is increasing but there is a need to describe their functional interactions. …”
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3614
Determination of mutagenicity of chemical compounds, physical factors and environmental pollutants by the Drosophila melanogaster wing somatic mutation and recombination test
Published 2016-03-01“…SMART can be used to evaluate the effect of various factors on the genome: physical (temperature, various types of radiation, electromagnetic fields), biogenic (genetic, physiological, infectious factors) and a wide range of chemical compounds. …”
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Transgenic plants as a model for studying еpigenetic regulation of gene expression
Published 2015-12-01Get full text
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3619
Bone Formation from Porcine Dental Germ Stem Cells on Surface Modified Polybutylene Succinate Scaffolds
Published 2016-01-01Get full text
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3620
Transcriptome Analysis of the Thymus in Short-Term Calorie-Restricted Mice Using RNA-seq
Published 2018-01-01Get full text
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