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Sexual dimorphism for juvenile body weight in chickens divergently selected for 8-week body weight
Published 2025-01-01“…It is very difficult to genetically modify sexual dimorphism in a particular population using the currently available conventional tools, and nature possesses homeostatic mechanisms that maintain stasis in a population.…”
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122
O laboratório em rede: fabricando transgênicos, construindo a sociedade
Published 2018-01-01“…Genetic Modified Organisms (GMOs) are still a big issue in the country. …”
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123
Gene Therapy for Glioblastoma Multiforme
Published 2025-01-01“…This review article will provide an update on various viral and nonviral vectors, their DNA and RNA cargoes, and how they genetically modify tumor cells and evoke therapeutic responses to GBM. …”
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124
Selective Autophagy in Drosophila
Published 2012-01-01“…Drosophila is an excellent genetically modifiable model organism exhibiting high conservation in the autophagic machinery. …”
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125
A Pilot Proteomic Analysis of Huntington’s Disease by Functional Capacity
Published 2025-01-01“…<b>Background:</b> The molecular biology of Huntington’s Disease (HD) has grown substantially, with pathological considerations extending to genetic modifiers, epigenetic changes, transcriptomics, the proteome, and the metabolome. …”
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126
Pancreatic Ductal Organoids React Kras Dependent to the Removal of Tumor Suppressive Roadblocks
Published 2019-01-01“…Here, we could establish and develop tools allowing us to isolate, culture, and genetically modify ductal mouse organoids. Transferred to known effectors in the IPMN-PDAC sequence, we could reveal significantly increased proliferative and self-renewal capacities for PTEN and RNF43 deficiency in the context of oncogenic KRASG12D in mouse pancreatic organoids. …”
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127
Marker-assisted identification of maize genotypes with improved protein quality
Published 2015-07-01“…In addition to the mutant o2 allele, QPM contains genetic modifiers that convert starchy endosperm of o2 mutant to the hard vitreous phenotype. …”
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128
Oligogenic effect is associated with the clinical heterogeneity of autosomal dominant deafness-15
Published 2025-01-01“…Meanwhile, three genes STRC, GJB2 and CDC14A were validated as POU4F3 new targets, implicating that the variants in the three genes may play a role of genetic modifier to generate a synergistic and enhancement effect on the progression of DFNA15.…”
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