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81
Biodesulfurization enhancement via targeted re-insertion of the flavin reductase dszD in the genome of the model strain Rhodococcus qingshengii IGTS8
Published 2025-01-01“…Here, we constructed a genetically modified R. qingshengii IGTS8 strain, which carries an additional copy of the flavin reductase gene dszD under the control of the rhodococcal promoter Pkap1, inserted in the neutral chromosomal genetic locus crtI. …”
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82
Engineered Bacillus subtilis WB600/ZD prevents Salmonella Infantis-induced intestinal inflammation and alters the colon microbiota in a mouse model
Published 2025-02-01“…In this study, we genetically modified Bacillus subtilis (B. subtilis) WB600 to express Zophobas atratus defensin (ZD), an antimicrobial peptide with broad-spectrum activity isolated from Zophobas atratus, for oral administration. …”
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83
Trans-kingdom sRNA silencing in the prevention and control of crop Fusarium wilt disease
Published 2025-01-01“…Concerning the safety and costly process of generating genetically modified crops, a plant-disease management strategy not reliant on transgenic approaches remains the most economic and environmental-friendly option. …”
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84
Viral and Nonviral Engineering of Natural Killer Cells as Emerging Adoptive Cancer Immunotherapies
Published 2018-01-01“…Alongside expressing chimeric antigen receptors to overcome immune escape by cancer cells, enhance their recognition, and mediate their killing, NK cells have been genetically modified to enhance their persistence in vivo by the expression of cytokines such as IL-15, avoid functional and metabolic tumor microenvironment suppression, or improve their homing ability, enabling enhanced targeting of solid tumors. …”
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85
Physicochemical and Biological Indicators of Soils in an Organic Farming System
Published 2021-01-01“…., the widespread use of biological preparations, a high proportion of legumes (sources of nitrogen), and avoiding chemical plant protection products, transgenic plants, and genetically modified organisms (GMOs). This study aims to increase the productivity of safflower and improve the physicochemical and biological indicators of dark chestnut soils through the use of biologized technologies in the organic farming system. …”
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86
Plant expression systems for production of recombinant pharmaceutically important proteins
Published 2018-01-01“…The prospects of creating plant (“edible”) vaccines based on genetically modified plants are discussed.…”
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87
THE NEW APPROACH ON FOOD QUALITY: AN IMPORTANT FACTOR ON CONSUMER BEHAVIOR AND TRENDS IN FOOD QUALITY
Published 2012-12-01“…The food energy content and the use of sugar and artificial sweeteners are the emerging issues, with the presence of genetically modified organisms and ecolabelling poised to become more prominent in the long-term.…”
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88
Plant genome modification: from induced mutagenesis to genome editing
Published 2022-11-01“…A new technology of genetic engineering and transgenesis enabled us to radically reduce the time required to obtain a new genetically-modified cultivar to one generation and make the modification process more effective and targeted. …”
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89
Situational analysis on porcine diseases of priority to pig industry: methods for biosecurity improvement in the Russian Federation holdings
Published 2024-12-01“…Based on the discussion results, automation and digitalization of all processes in pig industry, generation of genetically modified pigs not susceptible to the most significant pathogens such as African swine fever, classical swine fever, porcine reproductive and respiratory syndrome viruses and their use for production purposes, further research and implementation of integrated technological solutions for feed sanitation have been concluded to be the evolutionarily significant ways for effective pig farming intensification in the Russian Federation.…”
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90
The Calcium Sensor CBL-CIPK Is Involved in Plant’s Response to Abiotic Stresses
Published 2015-01-01“…Crosstalks between the CBL-CIPK complex and different abiotic stresses can extend our research area, which can improve and increase the production of genetically modified crops in response to abiotic stresses. …”
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91
Scientific provision of an effective development of soybean breeding and seed production in the Russian Far East
Published 2021-07-01“…All varieties are not genetically modified and are created mainly by classical breeding methods. …”
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92
Pivotal roles of melanopsin containing retinal ganglion cells in pupillary light reflex in photopic conditions
Published 2025-02-01“…Previous studies have investigated the roles of photoreceptors and ipRGCs in PLR using genetically-modified mouse models. Herein, we acutely ablated photoreceptors using N-nitroso-N-methylurea (MNU) to examine the roles of ipRGCs in the PLR. …”
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93
The perspectives of metabolomics studies of potato plants
Published 2017-03-01“…Metabolome profiling is widely employed to study differences between genetically modified forms of potatoes from untransformed relatives. …”
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94
A New Reference Plasmid “pGMT27” Provides an Efficient Transgenic Detection Method for Flue-Cured Tobacco
Published 2021-01-01“…For the detection of genetically modified (GM) tobacco, there is a lack of universal standard material which ultimately limits the detection methods because the accuracy and comparability of the results cannot be ensured. …”
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95
The impact of state policy on the development of organic agriculture in Azerbaijan
Published 2024-12-01“…The law prohibits the use of genetically modified organisms and chemicals, and sets standards for the certification of organic products. …”
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96
A descriptive-multivariate analysis of community knowledge, confidence, and trust in COVID-19 clinical trials amongst Ugandans working in healthcare settings.
Published 2021“…Skepticism against DNA recombinant vaccines (DRV) implies genetically modified vaccines such as the Oxford- AstraZeneca vaccine, Pfizer/BioNTech are bound to face a level of resistance once adapted in Uganda. …”
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97
Harnessing Genetic Resistance in Maize and Integrated Rust Management Strategies to Combat Southern Corn Rust
Published 2025-01-01“…<i>P. polysora</i> is an obligate biotrophic fungal pathogen that cannot be cultured in vitro or genetically modified, thus complicating the study of the molecular bases of its pathogenicity. …”
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98
Efficient chimeric mouse production using a novel embryonic stem cell line
Published 2017-02-01“…Embryonic stem cells could participate in the development of chimeric animals after injection into a blastocyst. Injection of genetically modified embryonic stem cells could lead to germ line transmission of a transgene or genomic modification in chimeric mice. …”
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99
Resistance to viruses of potato: current status and prospects
Published 2017-03-01“…However, these approaches have essential limitations because the acquired resistance is highly specific (against individual viruses only), is not durable, can be overcome by viruses and, finally due to regulatory bans on genetically modified organisms. Recently developed new genome editing technologies with the potential to be a powerful tool for gene design open up broad opportunities for development of next-generation resistance genes. …”
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100
Administration of a Next-Generation Probiotic Escherichia coli Nissle 1917-GLP-1 Alleviates Diabetes in Mice With Type 1 and Type 2 Diabetes
Published 2025-01-01“…In summary, the genetically modified EcN-GLP-1 strain demonstrates the ability to alleviate diabetes by enhancing the islet β-cell population, mitigating inflammatory reactions and apoptosis, optimizing liver lipid metabolism, and reinstating a balanced microbial diversity. …”
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