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Isotretinoin as a Possible Environmental Trigger to Autoimmunity in Genetically Susceptible Patients
Published 2017-01-01“…Mechanism of action for isotretinoin is not known but the drug may play a role in triggering autoimmunity in genetically susceptible individuals.…”
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Anxiety disorder, depression and coronary artery disease: associations and modification by genetic susceptibility
Published 2025-02-01“…This study investigated how genetic susceptibility to CAD alters these associations with incident CAD, comparing and combining anxiety disorder and depression. …”
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The association between type 2 diabetes and asthma incidence: a longitudinal analysis considering genetic susceptibility
Published 2025-01-01“…This association remained significant after further adjustments for genetic susceptibility to asthma. Furthermore, T2D increased the risk of developing asthma across both high and low genetic risk groups. …”
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A Systems Biology Overview on Human Diabetic Nephropathy: From Genetic Susceptibility to Post-Transcriptional and Post-Translational Modifications
Published 2016-01-01“…We performed a systematic analysis of the most relevant studies investigating genetic susceptibility and specific transcriptomic, epigenetic, proteomic, and metabolomic patterns in order to summarize the most significant traits associated with the disease onset and progression. …”
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Single Nucleotide Polymorphisms, Associated with Increased Risk of Irritable Bowel Syndrome with Predominant Constipation: A Meta Analysis
Published 2024-08-01Subjects: “…genetic susceptibility…”
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Genetic Nurture Effects on Type 2 Diabetes Among Chinese Han Adults: A Family-Based Design
Published 2025-01-01Subjects: Get full text
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Early-life tobacco smoke elevating later-life osteoporosis risk: Mediated by telomere length and interplayed with genetic predisposition
Published 2025-02-01Subjects: Get full text
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Association between CAPN-10 gene variant and diabetes mellitus in Nigeria: a review
Published 2025-02-01Subjects: Get full text
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Malignant Hyperthermia and Idiopathic HyperCKemia
Published 2011-01-01“…Genetic susceptibility testing should be considered if available and family members should also receive nontriggering agents when undergoing anesthesia and wear Medic Alert tags.…”
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Susceptibility Genes in Thyroid Autoimmunity
Published 2005-01-01“…The autoimmune thyroid diseases (AITD) are complex diseases which are caused by an interaction between susceptibility genes and environmental triggers. Genetic susceptibility in combination with external factors (e.g. dietary iodine) is believed to initiate the autoimmune response to thyroid antigens. …”
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Genetic Factors in Animal Models of Intestinal Inflammation
Published 1995-01-01“…The critical importance of host genetic susceptibility in determining chronicity, aggressiveness and complications of intestinal inflammation is clearly demonstrated by studies of inbred rodents, transgenic rats and spontaneous mutants. …”
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Somatic copy number deletion of chromosome 22q in papillary thyroid carcinoma
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Genetic Variations in the Human Angiotensin-ConvertingEnzyme 2 and Susceptibility to Coronavirus Disease-19
Published 2023-01-01“…In this study, genetic susceptibility to COVID-19 in different populations was investigated. …”
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Altered Immune Regulation in Type 1 Diabetes
Published 2013-01-01“…Genetic susceptibility, the impaired elimination of apoptotic β-cell remnants, altered immune regulatory functions, and environmental factors such as viral infections determine the outcome. …”
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Review of Inflammatory Bowel Disease in China
Published 2013-01-01“…In this review article, we provide the latest epidemiological trends in incidence, prevalence, and mortality of IBD patients in China and summarize the risk factors and genetic susceptibility of Chinese IBD patients. We also compare these characteristics to those of IBD patients in Western countries.…”
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Familial Multiple Sclerosis with Repetitive Relapses of Manic Psychosis in Two Patients (Mother and Daughter)
Published 2000-01-01“…We focused discussion on whether there may be a common genetic susceptibility to both illnesses or whether MS caused psychiatric manifestations. …”
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Rozwój genetyki i nauk żywieniowych a działania na rzecz zachowania zdrowia
Published 2005-12-01“…Knowledge of genetic susceptibility to disease will help identify people at enhance risk and their response to diet. …”
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Chorioamnionitis and Lung Injury in Preterm Newborns
Published 2013-01-01“…Short-term maturational effects on the lungs of extremely premature infants seem to be, however, accompanied by a greater susceptibility of the lung, eventually contributing to an increased risk of bronchopulmonary dysplasia (BPD). Genetic susceptibility to BPD is an evolving area of research and several studies have directly related the risk of BPD to genomic variants. …”
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