Corneal scarring after epithelium-off collagen cross-linking by Radhika Natarajan, Divya Giridhar

“…Individual patient factors such as variations in healing response and genetic predispositions, associated ocular allergy, and chronic contact lens wear can also impact scar development post-CXL. …”
Get full text

Enhancing rabbit farming efficiency with integrated genomics and nutritional strategies by Naqash Goswami, Ifeanyi Solomon Ahamba, Lionel Kinkpe, Ali Mujtaba Shah, Ye Xiangyang, Bing Song, Xianggui Dong, Shuhui Wang, Zhanjun Ren

“…This integration is particularly critical given the intricate interplay between genetic predispositions and nutritional demands in optimizing rabbit farming outcomes. …”
Get full text

Mechanism of Inflammation in Age-Related Macular Degeneration by Francesco Parmeggiani, Mario R. Romano, Ciro Costagliola, Francesco Semeraro, Carlo Incorvaia, Sergio D’Angelo, Paolo Perri, Paolo De Palma, Katia De Nadai, Adolfo Sebastiani

“…Risk factors of AMD are heterogeneous, mainly including increasing age and different genetic predispositions, together with several environmental/epigenetic factors, that is, cigarette smoking, dietary habits, and phototoxic exposure. …”
Get full text

From Multimorbidity to Network Medicine in Patients with Rheumatic Diseases by Winston Gilcrease, Luca Manfredi, Savino Sciascia, Fulvio Ricceri

“…For instance, rheumatic diseases such as rheumatoid arthritis and systemic lupus erythematosus are not just a collection of symptoms affecting various organs but are also interconnected through underlying systemic inflammatory processes, immune system dysregulation, and genetic predispositions.…”
Get full text

The different faces of GATA2 deficiency: implications for therapy and surveillance by Luca Vinci, Brigitte Strahm, Carsten Speckmann, Carsten Speckmann, Miriam Erlacher, Miriam Erlacher

“…GATA2 deficiency is one of the most common genetic predispositions to pediatric myelodysplastic syndrome (MDS) in children and adolescents. …”
Get full text

Oligodendrocyte Injury in Multiple Sclerosis. by Mateo Përgjegji, Klei Bame, Ketrina Ceka, Jera Cenalia , Sibora Bërdica , Teona Bushati

“…This disease arises from a complex interplay of genetic predispositions and environmental triggers that drive immune-mediated damage to oligodendrocytes and myelin proteins. …”
Get full text

Vitamin D and Selenium: Review of Clinical Trials of Synergistic Effects on Thyroid Antibody Levels and Disease Progression in Hashimoto’s Thyroiditis by Agnieszka Starzyk, Piotr Charzewski

“… Introduction: Hashimoto's Thyroiditis (HT) is a common autoimmune thyroid disorder caused by genetic predispositions and environmental factors, such as iodine imbalance, selenium deficiency, and stress. …”
Get full text

Effects of female sexual chemosignals on mucosal immunity in BALB/c and C57BL/6 male mice by G. V. Kontsevaya, E. A. Litvinova, M. P. Moshkin

“…However, the activation of mucosal immunity depends on the genetic predispositions of the immune response. BALB/c and C57BL/6 are prototypically Th2- and Th1-type mouse strains, respectively, therefore, they can serve as perfect model organisms for studying mechanism of lung mucosal immune activation in response to female chemosignals. …”
Get full text

Machine Learning with Tunicate Swarm Optimization for Improved Disc Herniation Prediction by Theofilos Gofas, Argyros Maris

“…The many variables that contribute to disc herniation are examined in this study, including age-related deterioration, genetic predispositions, lifestyle choices, and traumatic experiences. …”
Get full text

The association between type 2 diabetes and asthma incidence: a longitudinal analysis considering genetic susceptibility by Fei Chen, Ying Yang, Liping Yu, Lulu Song, Cong Zhang, Yifan He, Lili Wu, Wanlu Ma, Bo Zhang

“…Abstract Background The prevalence of type 2 diabetes (T2D) and asthma is rising, yet evidence regarding the relationship between T2D and asthma, particularly in the context of genetic predispositions, remains limited. Methods This study utilized data from the UK Biobank longitudinal cohort, involving 388,775 participants. …”
Get full text

Lipid Metabolism Alterations in Hyperlipidemic Dogs with Biliary Tract or Endocrine Diseases by Tae-Woo Kim, Min-Hee Kang, Hee-Myung Park

“…These changes may originate from genetic predispositions or underlying metabolic disorders, including cholestasis and endocrine diseases. …”
Get full text

Catalysts of change: Immunotherapy's frontier in oral oncology by Shyamaladevi Babu, Madhan Krishnan

“…These include risk factors such as tobacco use, alcohol intake, and infection with human papillomavirus (HPV), as well as genetic predispositions and environmental effects. Immunotherapy has become a potential approach to treating cancer by using the immune system to specifically target cancer cells, in contrast to traditional therapies that directly assault tumours. …”
Get full text

Association of endothelial nitric oxide synthase (NOS3) rs2070744 variant with advanced retinopathy of prematurity: a case–control study and meta-analysis by Aneta Choręziak-Michalak, Dawid Szpecht, Tomasz Woźniak, Anna Chmielarz-Czarnocińska, Patrycja Gazińska, Anna Gotz-Więckowska, Ewa Strauss

“…No associations were found between EDN1, EDNRA variants, and ROP. Exploring genetic predispositions in ROP, including vascular regulation genes, can lead to personalized prevention and treatment approaches. …”
Get full text

Genomic landscape of head and neck cancer in Asia: A comprehensive meta-analysis of 1016 samples by Srikanth S. Manda, Nafisa Arfa, Neha Sharma, Aparna R. Parikh, Thomas J. Roberts, Sewanti Limaye, Venkataraman Ramachandran, Kumar Prabhash, Moni A. Kuriakose, Prashant Kumar

“…The analysis highlights distinct genetic profiles influenced by environmental exposures, lifestyle habits, and genetic predispositions. Notably, the RAF family proteins, enriched in both Indian and Chinese cohorts, present potential therapeutic targets for RAF inhibitors like Vemurafenib. …”
Get full text

Colon Cancer Genetic and Epigenetic Changes, Etiopathogenesis, Risk Factors, Treatment: Literature Review by Gabrielė Ūbaitė, Aurelija Remeikaitė, Justas Žilinskas

“…The main reasons are ageing population, increased consumption of processed food, obesity, genetic predispositions. Aim. To review the latest scientific developments and novel factors on the epidemiology, etiology, pathoge­nesis of colon cancer, focusing on the influence of genetics and epigenetics, risk factors, and the advancement of prevention and treatment methods. …”
Get full text

Każde dziecko i każda jego cecha ma swoiste tempo rozwoju, modyfikowane przez warunki życia w danym okresie. (Raport 2 z dwuletnich comiesięcznych badań na Jukatanie w Meksyku)... by Napoleon Wolański, Armando Rojas, Graciela Valentin, Anna Siniarska

“…These phenomena depend rather on condition s in which the development of each individual occurs, as well as on its genetic predispositions and eco-sensitivity. It is probable, that differences in onset and intensity of pubertal spurt depend on alternations between periods of saltations and stasis of growth processes and on changes in body mass. …”
Get full text

Identification of new candidate genes for the hereditary predisposition to uveal melanoma: IGCMU trial by Mélanie Godiveau, Mélanie Godiveau, Mélanie Godiveau, Angeline Ginzac, Angeline Ginzac, Angeline Ginzac, Yannick Bidet, Yannick Bidet, Flora Ponelle-Chachuat, Flora Ponelle-Chachuat, Maud Privat, Maud Privat, Xavier Durando, Xavier Durando, Xavier Durando, Xavier Durando, Mathias Cavaillé, Mathias Cavaillé, Mathis Lepage, Mathis Lepage

“…Epidemiological studies have suggested an increased risk of prostate cancer, thyroid cancer, and leukemia among patients with UM, indicating potential unidentified genetic predispositions. This study aims to identify new candidate genes associated with a hereditary predisposition to UM.MethodsThis single-center study, conducted at Centre Jean Perrin, will involve the exome sequencing of 50 patients with UM who do not harbor known pathogenic variants in the BAP1 or MBD4 genes. …”
Get full text

Unraveling ankylosing spondylitis: Exploring the genetic and immunological factors and latest treatment innovations by Nilasree Hazra, Sudeshna Sengupta, Dipannita Burman, Jyoti Sekhar Banerjee, Malavika Bhattacharya

“…Environmental factors, like smoking, and genetic predispositions can worsen AS. Patients often have altered fecal microbiota, decreased Bacteroides and Lachnospiraceae, and increased Proteobacteria and Enterobacteriaceae. …”
Get full text

Prescribing clarity: mapping the link between antihypertensives and breast cancer by Shadman Newaz, Moontasir Ahmed, Jannat Ara Tina, Talukder Nasif Shahriar, Abdulla Bin Hridoy, Supritom Sarker, Mohammad Zakaria Al-Aziz, Md. Robed Amin

“…The role of the Renin-Angiotensin System and genetic predispositions emerged as important factors in these associations. …”
Get full text

IL-6–174 G/C transversion might decrease male infertility risk: A case-control study by Tayyebeh Zamani-Badi, Mohammad Karimian, Javad Amini Mahabadi, Atieh Rafatmanesh, Hossein Nikzad

“… Background: Genetic predispositions have been identified as important factors in male infertility. …”
Get full text