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81
Comparison of ox-LDL Levels in Diabetic Patients with Normo-, Micro-, and Macroalbuminuria with Their First Degree Relatives and the Healthy Control Group
Published 2012-01-01“…In conclusion, the presence and progression of albuminuria in diabetic patients are not related to ox-LDL concentration and genetic predisposition influences the plasma OX-LDL level. …”
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82
Cholestatic Hepatocellular Injury with Azathioprine: A Case Report and Review of the Mechanisms of Hepatotoxicity
Published 1998-01-01“…The strong association with male sex, and perhaps with human leukocyte antigen type, suggests a genetic predisposition of unknown type. Many of the symptoms of hepatotoxicity, such as nausea, abdominal pain and diarrhea, can be nonspecific and can be confused with a flare-up of inflammatory bowel disease. …”
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83
Mechanisms of bacterial-to-host interaction and their disorders at inflammatory bowel diseases
Published 2014-11-01“…At IBD, all mechanisms providing interaction of bacterial cells with the host body are malfunc tioning to some extent, that, in combination to genetic predisposition to this disease, results in development of clinical symptoms and morphological changes.…”
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84
The impact of gut microbiome on neuro-autoimmune demyelinating diseases
Published 2024-10-01“… Demyelinating diseases, including multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and chronic inflammatory demyelinating polyneuropathy (CIDP), are characterized by dysregulated immune responses to self-antigens, leading to myelin loss. Genetic predisposition and environmental factors, such as alterations in the gut microbiome, influence these conditions. …”
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85
Recent advances in genetics of aggressive behavior
Published 2018-09-01“…These and other evidence suggest that genetic predisposition to aggressive behavior may be a very complex process.…”
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86
Insight of microRNA role in Colorectal Cancer
Published 2020-05-01“…Numerous factors could contribute towards colorectal carcinogenesis and one of the factors is genetic predisposition. Mutations in the V-KiRas2 (Kras) oncogene have been implicated in 30-50% of the colorectal cancer patients and usually lead to poorer prognosis. …”
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87
Muscle parameters in men and oxidative stress markers
Published 2025-01-01“…Factors like lifestyle, diet, and genetic predisposition, which were not controlled in this study, could also influence the observed outcomes and should be included in future research.…”
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88
Treatment of tardive dyskinesia caused by long-term antipsychotic use: case reports and literature review
Published 2020-12-01“…In order to provide reliable evidence-based recommendations for the treatment of tardive dyskinesia and to better understand its pathophysiology, genetic predisposition, and therapeutic agents, more studies with larger samples and more uniform conditions are needed. …”
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89
Multifocal Breast Cancer in Young Women with Prolonged Contact between Their Breasts and Their Cellular Phones
Published 2013-01-01“…Breast cancer occurring in women under the age of 40 is uncommon in the absence of family history or genetic predisposition, and prompts the exploration of other possible exposures or environmental risks. …”
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90
The Challenges of Distinguishing Different Causes of TMA in a Pregnant Kidney Transplant Recipient
Published 2024-01-01“…TMA disorders are well-recognised in kidney transplant recipients, often due to an underlying genetic predisposition related to complement dysregulation, or de novo due to infection, immunosuppression toxicity, or antibody-mediated rejection. …”
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91
Case Study: Analyzing CFTR Mutations and SNPs in Pulmonary Fibrosis Patients with Unclear Symptoms
Published 2024-01-01“…Consanguinity and family history highlight genetic predisposition, while environmental factors may influence symptom onset. …”
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92
Migraine and restless legs syndrome – is there an association?
Published 2023-10-01“…It is believed that the occurrence of both diseases is determined by several pathophysiological factors, such as the activity of the dopamin- ergic system, iron deficiency, genetic predisposition, and changes in the gray matter of the brain. …”
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93
The Composition of Gut Microbiota in Patients Bearing Hashimoto’s Thyroiditis with Euthyroidism and Hypothyroidism
Published 2020-01-01“…Hashimoto’s thyroiditis (HT), a type of autoimmune disease, occurs due to genetic predisposition and environmental factors. It is well known that thyroid function may affect the gut microbiota. …”
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94
Association of Fibrinogen Aα Thr312Ala (rs6050) Polymorphism with Venous Thrombosis and Chronic Thromboembolic Pulmonary Hypertension: A Meta-Analysis
Published 2025-01-01“…The pathogenesis of them involves multiple risk factors such as genetic predisposition. However, the findings from these studies are not entirely consistent. …”
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95
Hemophilia A Haplotypes in Southwestern Iran
Published 2025-01-01“…Several factors contribute to the prevalence and incidence of hemophilia A in southwestern Iran, including genetic predisposition, consanguineous marriages, and limited access to comprehensive healthcare services. …”
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96
The causal impact of smoking behavior on osteoarthritis: a Mendelian randomization analysis
Published 2025-01-01“…To confirm the robustness of the results, sensitivity analysis using Leave-One-Out (LOO), level pleiotropy testing (MR Egger intercept test and MR-PRESSO), and heterogeneity testing were performed.ResultsSummary-level MR analysis revealed a positive correlation between genetic predisposition for smoking and the likelihood of developing OA. …”
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97
Therapeutic role of isoflavones from traditional medicine in the management of polycystic ovary syndrome
Published 2025-03-01“…The etiology of PCOS involves a complex interplay of factors, including genetic predisposition, neuroendocrine dysregulation, contemporary lifestyle practices, and obesity. …”
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98
Acne Vulgaris Management: A Review of First-Line and Advanced Pharmacological Treatments
Published 2025-02-01“…Several factors predispose individuals to the development of acne, including hormonal imbalances, genetic predisposition, and the use of certain medications. …”
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99
The Epidemiology, Burden, Risk Factors, Presentations, and Challenges of Evaluating and Managing Patients with Pulmonary Hypertension in Nigeria – A Short Review
Published 2024-12-01“…The etiology of PH can vary and may include factors such as genetic predisposition, underlying medical conditions such as heart or lung diseases, or exposure to certain drugs or toxins. …”
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100
The Protective Role of Ambient Ultraviolet Radiation Against Dementia: An Ecological Analysis of Global Data
Published 2025-01-01“…Confounding factors, including aging, economic affluence, genetic predisposition, and urbanization, were controlled to ensure robust results. …”
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