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The Association between Gly460Trp-Polymorphism of Alpha-Adducin 1 Gene (ADD1) and Arterial Hypertension Development in Ukrainian Population
Published 2021-01-01“…Arterial hypertension (AH) belongs to the diseases with genetic predisposition that determines the necessity of research on the genetic component’s influence on this disease development. …”
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62
Functional and Practical Insights Into the Genetic Basis of Takayasu Arteritis
Published 2025-01-01“…Although the exact etiology of TAK remains unclear, a genetic predisposition to the disease has been established. …”
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63
Blood Vessel Segmentation and Classification of Diabetic Retinopathy with Machine Learning-Based Ensemble Model
Published 2024-09-01“…The incidence of diabetes has increased in recent times due to factors such as obesity and genetic predisposition. Diabetes wears out the eye vessels over time. …”
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64
Finding Genetic Risk Factors of Gestational Diabetes
Published 2012-12-01“…Gestational diabetes mellitus (GDM) is a complex metabolic disorder of pregnancy that is suspected to have a strong genetic predisposition. It is associated with poor perinatal outcome, and both GDM women and their offspring are at increased risk of future development of type 2 diabetes mellitus (T2DM). …”
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65
Age-related features of alpha rhythm dynamics: a brief review
Published 2025-01-01“…Parameters of the alpha rhythm, such as individual stability, genetic predisposition, and age-related characteristics, make it a promising marker for both normative development and brain aging in determining cognitive and biological age.…”
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66
Severe Rhabdomyolysis Associated with Simvastatin and Role of Ciprofloxacin and Amlodipine Coadministration
Published 2015-01-01“…In addition to age, gender, ethnicity, genetic predisposition, and dose, drug-drug interactions play a major role. …”
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67
A modern approach to the treatment of plaque psoriasis
Published 2019-12-01“…The etiopathogenesis of the disease is multifactorial, the key factors being genetic predisposition combined with immunological disorders, environmental factors and skin barrier damage. …”
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68
Plotting of Ethylene Glycol Blood Concentrations Using Linear Regression before and during Hemodialysis in a Case of Intoxication and Pharmacokinetic Review
Published 2015-01-01“…Pharmacokinetic review revealed minimal elimination of EG by alcohol dehydrogenase (ADH) which could be related to genetic predisposition for ADH activity and home medications as well as presence of propylene glycol. …”
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69
An Acta Orthopaedica educational article: Treatment of pediatric spondylolysis and spondylolisthesis
Published 2025-01-01“…The etiology of spondylolysis is regarded as a stress fracture due to repetitive loading associated with a genetic predisposition. Lumbar magnetic resonance imaging (MRI) shows an increased signal intensity before an actual fracture line develops. …”
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70
Whole transcriptomic and proteomic analyses of an isogenic M. tuberculosis clinical strain with a naturally occurring 15 Kb genomic deletion.
Published 2017-01-01“…These include the ability of the host to control the infection which may directly relate to nutritional status, presence of co-morbidities and genetic predisposition. Pathogen factors, in particular the ability of different Mycobacterium tuberculosis strains to respond to the harsh environment of the host granuloma, which includes low oxygen and nutrient availability and the presence of damaging radical oxygen and nitrogen species, also play an important role in the success of different strains to cause disease. …”
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71
Susceptibility to Aneuploidy in Young Mothers of Down Syndrome Children
Published 2009-01-01“…That study indicated that women who have a DS child at a young age might have a genetic predisposition to chromosome malsegregation in both somatic and germ line cells. …”
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72
Nucleoside analogues in treatment of liver cirrhosis as an outcome of chronic hepatitis B
Published 2009-02-01“…Rates of progression of persistent HBV infection to liver cirrhosis stage depend on several factors – spectrum of viral markers, immune status of the patient, his/her age, gender, genetic predisposition, etc. Lamivudine has capacity for prolonged and persistent block of HBV replication. …”
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73
Asthma in Sickle Cell Disease
Published 2011-01-01“…In patients with a genetic predisposition of atopic asthma, these changes are probably more severe and result in increased susceptibility to sickle cell complications. …”
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74
New insights on genetic background of major diabetic vascular complications
Published 2024-10-01“…An increasing body of research points to the importance of genetic predisposition in the onset of both diabetes and diabetic vascular complications. …”
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75
Challenges in the diagnosis and management of autoimmune hemolytic anemia: A case-based approach. Experience from a tertiary care hospital in the Haryana region
Published 2024-12-01“…The pathogenesis of AIHA is complex interplay between genetic predisposition, immune dysregulation and enviornmental triggers. …”
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FROM ONCOLOGIST TO SURGEON - GENETICS IN COLORECTAL METASTASIS FOR SURGEONS
Published 2025-02-01“…The percentage of patients with a true hereditary genetic predisposition is less than 10%, and these are related to the presence or absence of colonic polyps as an important manifestation of the disease. …”
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Hemophagocytic syndrome: Laboratory and molecular characterization
Published 2024-12-01“…The syndrome can occur as a primary/familial form mostly affecting infants and young children or as an acquired form secondary to an underlying pathology (infection, malignancy, and autoimmune disease) that may have an underlying genetic predisposition, including mutations or polymorphisms. …”
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Familial Aggregation for Ischemic Heart Disease
Published 2022-09-01“…<strong>Background:</strong> ischemic heart disease is a nosological entity of multifactorial origin with genetic predisposition and susceptible to environmental changes. …”
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Diagnosis and treatment of the functional dyspepsia: clinical guidelines of the Russian Gastroenterological Association
Published 2018-08-01“…It’s etiology includes genetic predisposition, bad habits, previous intestinal infections, psychosocial factors. …”
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Folie à Deux in the Setting of COVID-19 Quarantine
Published 2022-01-01“…The preconditions that must exist for folie à deux to develop are an intimate emotional association between the inducer and the induced and a genetic predisposition to psychosis, such as blood relations with primary relatives. …”
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