Polymorphism of genes associated with infectious lung diseases in Northern Asian populations and in patients with community-acquired pneumonia by S. V. Mikhailova, L. V. Shcherbakova, N. I. Logvinenko, I. I. Logvinenko, M. I. Voevoda

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Familial Pemphigus Vulgaris Occured in a Father and Son as the First Confirmed Cases by Ali Haydar Eskiocak, Birgul Ozkesici, Soner Uzun

“…Although there is some evidence pointing towards a genetic predisposition by some human leukocyte antigen (HLA) genes, familial occurrence of PV is very rare. …”
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Type 1 Diabetes (T1D) and Latent Autoimmune Diabetes in Adults (LADA): The Difference Between a Honeymoon and a Holiday by Livia M. R. Marcon, Carmine G. Fanelli, Riccardo Calafiore

“…In young persons with a genetic predisposition, it usually manifests after being exposed to environmental triggers. …”
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Unique Case Report of a Meningeal Sarcoma Arising during Ongoing Treatment for Progressing Intraparenchymal Glioma by Richard A. Peterson, Bhavani Kashyap, Pamala A. Pawloski, Anna C. Forsberg, Leah R. Hanson

“…It remains unclear whether the sarcoma was induced by the radiation treatment or a genetic predisposition.…”
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A retrospective single-center pilot study of the genetic background of the transplanted kidney. by Anna Novotna, Klara Horackova, Jana Soukupova, Petra Zemankova, Petr Nehasil, Pavel Just, Ludek Voska, Petra Kleiblova, Silvie Rajnochova Bloudickova

“…<h4>Materials and methods</h4>This retrospective single-center pilot study aimed to identify a potential genetic predisposition to RCC of the transplanted kidney and outcome in KTR who underwent single kidney transplantation between January 2000 and December 2020 and manifested RCC of the transplanted kidney. …”
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Role of autophagy defects and significance of adherent-invasive <i>Escherichia coli</i> in Crohn's disease development by I. V. Mayev, D. N. Andreev, D. V. Rakitina, Yu. P. Baykova

“…According to modern concept, etiology of CD has complex nature and is determined by genetic predisposition, infectious agents and environmental factors. …”
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Expression of palmitoyl transferases in brain structures of mice genetically predisposed to depressive-like behavior by E. M. Kondaurova, T. V. Ilchibaeva, A. S. Tsybko, Е. G. Ponimaskin, V. S. Naumenko

“…However, the study demonstrates that the genetic predisposition to depression-like behavior in ASC mice is not associated with changes in ZDHHC5, ZDHHC9, or ZDHHC21 palmitoyl transferase expression.…”
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Systemic Lupus Erythematosus (SLE): A review on the prevalence, clinical manifestation, and disease assessment by Malarvili Selvaraja, Maha Abdullah, Anim Md Shah, Masita Arip, Syafinaz Amin Nordin

“…The aetiology of SLE is not fully understood, but both genetic predisposition and ecological triggers are thought to be involved in the disease manifestation. …”
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Ketamine Therapy in Complex Cases: A Cautionary Tale of Exacerbated Personality Traits and the Crucial Role of Comprehensive Follow-Up and Psychosocial Interventions by Jai Ahuja, Luba Leontieva

“…The report delves into the patient’s complex background, including psychosocial stressors, genetic predisposition to depression, and a history of personality traits that may have influenced her response to ketamine. …”
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Non-Scarring Alopecia in Females: A Comprehensive Review by Miguel A. Aristizabal, Alison J. Bruce, Roy S. Rogers III, Thais Pincelli

“…Various aetiologic factors are implicated in non-scarring alopecia, including genetic predisposition, loss of immune privilege, oxidative damage, and hormonal fluctuations. …”
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Primary Biliary Cirrhosis in A Patient with Turner Syndrome by Piotr Milkiewicz, Jenny Heathcote

“…The present case may support the importance of X chromosome genes in the development of genetic predisposition to PBC, and emphasizes the necessity for a systematic study of the prevalence of PBC in patients with Turner syndrome.…”
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Development of Personalized Periodontal Treatment Approaches: Integration of Genetic, Environmental, and Clinical Factors by Rajneesh Maheshwari, Iman Baig, Sana Zeba, Mamta Singh, Shilpi Tyagi, Prashansa Sharma

“…Periodontal diseases are multifactorial, influenced by genetic predisposition, environmental factors, and clinical conditions. …”
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Circulating Monocyte and Lymphocyte Populations in Healthy First-Degree Relatives of Type 2 Diabetic Patients at Fasting and during Short-Term Hyperinsulinemia by Michaela Šiklová, Eva Krauzová, Barbora Svobodová, Jana Kračmerová, Marek Štěpán, Michal Koc, Vladimír Štich, Lenka Rossmeislová

“…The alterations of the CD4/CD8 lymphocyte ratio, relative content of TH17 cells, and intermediate monocytes in FDR are features of genetic predisposition to T2DM and may play a role in pathogenesis of T2DM. …”
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Familial Prevalence of Inflammatory Bowel Disease in Northern Alberta by BR Pinchbeck, J Kirdeikis, ABR Thomson

“…These results support the hypothesis that a genetic predisposition in families combined with possible environmental and lifestyle influences determine the relative risk of developing Crohn's disease and ulcerative colitis.…”
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Understanding cancer predisposition in Singapore: what’s next by Jianbang Chiang, Tarryn Shaw, Joanne Ngeow

“…Knowledge of an underlying genetic predisposition to cancer allows the use of personalised prognostic, preventive and therapeutic strategies for the patient and carries clinical implications for family members. …”
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Dysbiosis in the Pathogenesis of Pediatric Inflammatory Bowel Diseases by Donatella Comito, Claudio Romano

“…Microbial dysbiosis in IBD with lack of beneficial bacteria, together with genetic predisposition, is the most relevant conditions in the pathogenesis of the pediatric IBD.…”
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Alopecia as the first manifestation of azathioprine myelosuppression in a genetically predisposed patient by Debashish Mishra, Shefali Khanna Sharma, Aman Sharma, Sanjay Jain, Varun Dhir

“…The latter group often manifests with sudden cytopenias and is often secondary to a genetic predisposition. Mutations in the genes thiopurine S-methyltransferase (TPMT) and nucleoside diphosphate-linked moiety X-type motif 15 (NUDT15) have been identified to predispose to severe myelosuppression with azathioprine. …”
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Aortic Disease in the Young: Genetic Aneurysm Syndromes, Connective Tissue Disorders, and Familial Aortic Aneurysms and Dissections by Marcelo Cury, Fernanda Zeidan, Armando C. Lobato

“…In the absence of familial history and other clinical findings, the proportion of thoracic and abdominal aortic aneurysms and dissections resulting from a genetic predisposition is still unknown. In this study, we propose the review of the current genetic knowledge in the aortic disease, observing, in the results that the causative genes and molecular pathways involved in the pathophysiology of aortic aneurysm disease remain undiscovered and continue to be an area of intensive research.…”
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Peripartum cardiomyopathy: current state of the problem by Ya.M. Lutai

“…PCMP has a rather heterogeneous and incompletely studied pathophysiology, which includes hormonal, vascular, metabolic, and immunological pathways, whose implementation becomes possible on the background of genetic predisposition. Treatment is based on heart failure therapy, taking into account the risks associated with pregnancy and lactation. …”
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Isotretinoin as a Possible Environmental Trigger to Autoimmunity in Genetically Susceptible Patients by Jocelyn Nugroho, Bahareh Schweiger

“…Emergence of autoimmune thyroid diseases depends upon genetic predisposition and environmental triggers. Mechanism of action for isotretinoin is not known but the drug may play a role in triggering autoimmunity in genetically susceptible individuals.…”
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