Exploring space: ethical dilemmas for catholicism by Maurizio Balistreri

“…Non-therapeutic genetic modifications, regarded by the Church as an arbitrary redesign of human nature, are categorically prohibited. …”
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A REVIEW ON RECENT ADVANCES IN ANIMAL BIOTECHNOLOGY by Sarada Bhandari, Lokendra Nath Yogi

“…Recent advancements encompass various domains, including genetic editing techniques like CRISPR-Cas9, which allow precise genetic modifications for improved animal health and product quality. …”
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Executioner caspases degrade essential mediators of pathogen-host interactions to inhibit growth of intracellular Listeria monocytogenes by Marilyne Lavergne, Raffael Schaerer, Sara De Grandis, Safaa Bouheraoua, Oluwadamilola Adenuga, Tanja Muralt, Tiffany Schaerer, Léa Chèvre, Alessandro Failla, Patricia Matthey, Michael Stumpe, Dieter Kressler, Pierre-Yves Mantel, Michael Walch

“…Here, by means of chemical and genetical modifications, we show that the executioner caspases-3 and -7 efficiently inhibit growth of intracellular Listeria monocytogenes in host cells. …”
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Synthetic Gene Drives in Plants: Development Strategies, Potential Applications, and Ethical Considerations by Yawen Liu, Bingke Jiao, Wenfeng Qian

“…One innovative approach involves the use of gene drives, a technology that enables targeted genetic modifications to transmit at a super Mendelian rate (>50%) and therefore, rapidly propagate through natural populations. …”
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Quantum Dots Do Not Alter the Differentiation Potential of Pancreatic Stem Cells and Are Distributed Randomly among Daughter Cells by S. Danner, H. Benzin, T. Vollbrandt, J. Oder, A. Richter, C. Kruse

“…We report here that QDs offered an efficient and nontoxic way to label pancreatic stem cells without genetic modifications. In summary, QD nanocrystals are a promising tool for stem cell labeling and facilitate tracking of transplanted cells in animal models.…”
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Biodesulfurization enhancement via targeted re-insertion of the flavin reductase dszD in the genome of the model strain Rhodococcus qingshengii IGTS8 by Olga Martzoukou, Fotios Klenias, Eleni Kopsini, Dimitris G. Hatzinikolaou

“…However, naturally occurring biocatalysts do not exhibit the required BDS activity to be useful for industrial applications and for this reason, genetic modifications are currently being explored. Here, we constructed a genetically modified R. qingshengii IGTS8 strain, which carries an additional copy of the flavin reductase gene dszD under the control of the rhodococcal promoter Pkap1, inserted in the neutral chromosomal genetic locus crtI. …”
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Transcriptional engineering for value enhancement of oilseed crops: a forward perspective by Charli Kaushal, Mahak Sachdev, Mansi Parekh, Harini Gowrishankar, Mukesh Jain, Subramanian Sankaranarayanan, Bhuvan Pathak

“…Advances in genome editing tools like CRISPR/Cas9 offer precise genetic modifications, targeting transcription factors and binding sites to enhance desirable traits, such as the nutritional profile and chemical composition of fatty acids. …”
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Pan-Cancer Analysis of the Prognostic and Immunotherapeutic Value of PDGFB by Bai Y, Wang X, Wang B

“…In addition, clinical samples were validated using immunohistochemistry.Results: Our findings revealed that PDGFB was highly expressed in a diverse range of cancer types, and its expression and genetic modifications were significantly associated with clinical outcomes in certain tumors. …”
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Transcriptomic Profile Analysis of Brain Tissue in the Absence of Functional TRPM8 Calcium Channel by Erick B. Saldes, Alexandra Erdmier, Jai Velpula, Timothy E. Koeltzow, Michael X. Zhu, Swapna Asuthkar

“…The activation and deactivation of TRPM8 occur through genetic modifications, channel interactions, and signaling cascades. …”
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The generation and evaluation of TKO/hCD55/hTM/hEPCR gene-modified pigs for clinical organ xenotransplantation by Guoli Huai, Yong Wang, Jiaxiang Du, Zhenhui Cheng, Yuxuan Xie, Jia Zhou, Hongmei Tang, Yanyan Jiang, Xiangyang Xing, Shaoping Deng, Dengke Pan, Dengke Pan, Dengke Pan

“…However, the optimal combination of genetic modifications and their expression levels for initial clinical trials remains unclear. …”
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