Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast. by Tonibelle Gatbonton, Maria Imbesi, Melisa Nelson, Joshua M Akey, Douglas M Ruderfer, Leonid Kruglyak, Julian A Simon, Antonio Bedalov

“…Furthermore, our results laid the foundation for studying genetic determinants of telomere length-variation and their roles in human disease.…”
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History and prospects of flax genetic markers by Daiana A. Zhernova, Elena N. Pushkova, Tatiana A. Rozhmina, Elena V. Borkhert, Alexander A. Arkhipov, Alexander A. Arkhipov, Elizaveta A. Sigova, Elizaveta A. Sigova, Ekaterina M. Dvorianinova, Ekaterina M. Dvorianinova, Alexey A. Dmitriev, Alexey A. Dmitriev, Nataliya V. Melnikova

“…Successful flax breeding requires knowledge on the genetic determinants of flax traits. The former identification of molecular markers for valuable traits used labor-intensive and sometimes poorly reproducible approaches. …”
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A One Health approach for the genomic characterization of antibiotic-resistant Campylobacter isolates using Nanopore whole-genome sequencing by Ana Hurtado, Medelin Ocejo, Beatriz Oporto, José Luis Lavín, Ruth Rodríguez, María Ángeles Marcos, Mikel Urrutikoetxea-Gutiérrez, Mikel Urrutikoetxea-Gutiérrez, Miriam Alkorta, Miriam Alkorta, Miriam Alkorta, José María Marimón, José María Marimón

“…In response to the growing threat posed by the spread of antimicrobial resistance in zoonotic Campylobacter, a One Health approach was used to examine the genomic diversity, phylogenomic relationships, and the distribution of genetic determinants of resistance (GDR) in C. jejuni and C. coli isolates from humans, animals (ruminants, swine, and chickens), and avian food products collected during a regionally (Basque Country, Spain) and temporally (mostly 2021–2022) restricted sampling. …”
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Mineral Composition and Baking Value of the Winter Wheat Grain under Varied Environmental and Agronomic Conditions by Iwona Jaskulska, Dariusz Jaskulski, Lech Gałęzewski, Tomasz Knapowski, Wojciech Kozera, Roman Wacławowicz

“…Opal cultivar grain of the genetically determined prime-quality wheat was obtained in a two-year field experiment (varied soil and weather). …”
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Rare Somatic MEN1 Gene Pathogenic Variant in a Patient Affected by Atypical Parathyroid Adenoma by Luigia Cinque, Flavia Pugliese, Celeste Clemente, Stefano Castellana, Maria Pia Leone, Danilo de Martino, Teresa Balsamo, Claudia Battista, Tommaso Biagini, Paolo Graziano, Marco Castori, Alfredo Scillitani, Vito Guarnieri

“…We suggest that MEN1 gene could be an underestimate genetic determinant of these rare histological entities, and we highlight the utility of a complete genetic screening protocol, by the use of next-generation sequencing technology in such undetermined clinical cases with no frank clinical presentation.…”
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Is Vitamin D Deficiency the Cause or the Effect of Systemic Lupus Erythematosus: Evidence from Bidirectional Mendelian Randomization Analysis by Yang Ding, Shengyi Yang, Shasha Fan, Yi Tang, Yan Teng, Xiaohua Tao, Wei Lu

“…These findings indicated that genetically determined SLE had a negative effect on the vitamin D and 25-hydroxyvitamin D levels. …”
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Genetic coupling of enhancer activity and connectivity in gene expression control by Helen Ray-Jones, Chak Kei Sung, Lai Ting Chan, Alexander Haglund, Pavel Artemov, Monica Della Rosa, Luminita Ruje, Frances Burden, Roman Kreuzhuber, Anna Litovskikh, Eline Weyenbergh, Zoï Brusselaers, Vanessa Xue Hui Tan, Mattia Frontini, Chris Wallace, Valeriya Malysheva, Leonardo Bottolo, Elena Vigorito, Mikhail Spivakov

“…Jointly, our findings suggest an inherent genetic coupling of enhancer activity and connectivity in gene expression control relevant to human disease and highlight the regulatory role of genetically determined chromatin boundaries.…”
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Geographical distribution of eight neuromuscular disorders in the Netherlands based on a nationwide registry by Johanna C.W. Deenen, André L.M. Verbeek, Pieter A. van Doorn, Catharina G. Faber, Anneke J. van der Kooi, Nicolette C. Notermans, Jan J.G.M. Verschuuren, Baziel G.M. van Engelen, Nicol C. Voermans

“…Geographical mapping of the specific disorders is expected to provide valuable insights into clustering of the conditions, which points to possible environmental and genetical determinants. So far, mostly geographical maps of motor neuron diseases have been reported. …”
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Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice by Kamila Borowczyk, Jacek Wróblewski, Joanna Suliburska, Noriyuki Akahoshi, Isao Ishii, Hieronim Jakubowski

“…In the present work, we studied the prevalence and genetic determinants of keratin damage caused by homocysteinylation. …”
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Mapping dynamic regulation of gene expression using single-cell transcriptomics and application to complex disease genetics by Hanna Abe, Phillip Lin, Dan Zhou, Douglas M. Ruderfer, Eric R. Gamazon

“…Using longitudinal, genetically determined expression, we implement a predictive causality framework, evaluating the prediction of future values of a target gene expression using prior values of a putative regulatory gene. …”
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A genome-wide association study of high-sensitivity C-reactive protein in a large Korean population highlights its genetic relationship with cholesterol metabolism by Kwangyeon Oh, Minju Yuk, Soyoun Yang, Jiyeong Youn, Qian Dong, Zhaoming Wang, Nan Song

“…It suggests that increase in genetically determined hsCRP may contribute to a decrease in cholesterol level and a strong oxidative environment in the blood vessel. …”
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Genetic diversity in wild species and cultivars of strawberry for the <i>FanAAMT</i> gene controlling fruit flavor volatiles by A. S. Lyzhin, I. V. Luk’yanchuk

“…Identification of genetic determinants for this trait facilitates targeted selection of promising forms based on diagnostic DNA markers. …”
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FEATURES OF THE CLINICAL COURSE OF PSORIASIS IN PATIENTS WITH OBESITY by Ya.O. Yemchenko, K.Ye. Ischeikin

“…Psoriasis is the most common chronic, genetically determined autoimmune polyetiological inflammatory disease with impaired epidermal proliferation, provoked by exogenous and endogenous factors, and manifested by erythematous and scaly elements, papules and plaques. …”
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PYROSEQUENCING: ITS POTENTIAL AND LIMITATIONS IN DIAGNOSIS OF INHERITED DISEASES IN CATTLE by Н. A. Kirsanova, A. V. Sukhoedova, M. A. Pleskacheva, I. V. Soltynskaya, I. A. Timofeeva, О. V. Prasolova, E. V. Krylova

“…In particular, more than 500 genetically determined morphological and functional disorders have been detected in cattle; for 150 of them, specifi c mutations are known. …”
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Correcting scale distortion in RNA sequencing data by Christopher Thron, Farhad Jafari

“…This is now regularly used for population-based studies designed to identify genetic determinants of various diseases. Naturally, the accuracy of these tests should be verified and improved if possible. …”
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On the human nature (following in the steps of Belyaev) by A. L. Markel

“…In response to the culture development, the genetic determination of human cognitive processes also changed. …”
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Rheumatoid Arthritis, Circulating Inflammatory Proteins, and Hypertension: A Mendelian Randomization Study by Guobing Jia, Tao Guo, Lei Liu, Chengshi He

“…Our study identifies causal relationships between several genetically determined inflammatory proteins and hypertension, establishing that RA increases hypertension risk, with inflammation partially mediating this effect. …”
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Molecular genetic factors influencing outcomes of <i>Helicobacter pylori</i> infection at Khakasia republic inhabitants by Ye. S. Ageyeva, O. V. Shtygasheva, N. V. Ryazantseva, V. V. Tsukanov

“…Population-based genetic determinants (СС +3954 IL1β, R4/R4 IL1Ra), that establish higher protection level from H. pylori-associated diseases at Khakases, than at Caucasians were revealed. …”
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‘Vychegodsky’: a new potato cultivar for the Republic of Komi by A. G. Tulinov, A. Yu. Lobanov

“…The cultivar demonstrates high field resistance to major potato diseases, and genetically determined resistance to wart disease and golden potato nematode.Conclusion. …”
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Genetics of aging and longevity by A. A. Moskalev, E. N. Proshkina, A. A. Belyi, I. A. Solovyev

“…The objective of this review is to summarize the available information about underlying genetic determinants of longevity and aging. Genes and signaling pathways that regulate stress response, metabolism, growth of cells and organism, maintaining of genome and proteome integrity, qualitative and quantitative mitochondria composition, inflammatory response, apoptosis and selection of viable cells, as well as circadian rhythms were considered. …”
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