Immunogenetic Factors Associated with Severe Respiratory Illness Caused by Zoonotic H1N1 and H5N1 Influenza Viruses by Jennifer Juno, Keith R. Fowke, Yoav Keynan

“…An understanding of the host genetic determinants of susceptibility and severe respiratory illness, however, is currently lacking. …”
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Flexibilité vocale sous influences sociales chez les primates non-humains by Hélène Bouchet, Marion Laporte, Agnès Candiotti, Alban Lemasson

“…However, in contrast with human language, vocal communication in monkeys and apes, our closest living relatives, has long been described as rigid and strongly genetically determined. In recent years, evidences of vocal flexibility under social influences have nonetheless been provided in nonhuman primates. …”
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Atlas of multilineage stem cell differentiation reveals TMEM88 as a developmental regulator of blood pressure by Sophie Shen, Tessa Werner, Samuel W. Lukowski, Stacey Andersen, Yuliangzi Sun, Woo Jun Shim, Dalia Mizikovsky, Sakurako Kobayashi, Jennifer Outhwaite, Han Sheng Chiu, Xiaoli Chen, Gavin Chapman, Ella M. M. A. Martin, Di Xia, Duy Pham, Zezhuo Su, Daniel Kim, Pengyi Yang, Men Chee Tan, Enakshi Sinniah, Qiongyi Zhao, Sumedha Negi, Meredith A. Redd, Joseph E. Powell, Sally L. Dunwoodie, Patrick P. L. Tam, Mikael Bodén, Joshua W. K. Ho, Quan Nguyen, Nathan J. Palpant

“…Together, this study provides an atlas of multilineage stem cell differentiation and analysis pipelines to dissect genetic determinants of mammalian developmental physiology.…”
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Diverse Linguistic Development in Prelingually Deaf Children with Cochlear Implants by Pia De Stefano, Francesco Pisani, Giuseppe Cossu

“…We report 4 prelingually deaf children (mean age=10.5; SD=1.08), affected by a genetically determined bilateral deafness, due to GJB2 gene mutation Cx26. …”
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Prenatal gene-environment interactions mediate the impact of advanced maternal age on mouse offspring behavior by Marta Marlena Ziętek, Aneta Jaszczyk, Adrian Mateusz Stankiewicz, Silvestre Sampino

“…These findings disentangle the relationship between genetic determinants and maternal age-related factors in shaping the emergence of autism-like behaviors in mice, highlighting the interplay between maternal age, genetic variability, and prenatal programming, in the occurrence of neurodevelopmental disorders.…”
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Case of surgical treatment of ascending aorta and aortic arch aneurysm in a patient with unclassified connective tissue disease by B.M. Todurov, A.Y. Shkandala, O.V. Zelenchuk, M.F. Rotar, N.S. Gnoyanko

“…The very fact of detecting an aneurysm of the thoracic aorta requires careful phenotypic examination and search for genetically determined pathology. The results of the phenotypic study confirm the hereditary nature of the detected pathology. …”
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An overview of hereditary spherocytosis and the curative effects of splenectomy by Kyril Turpaev, Elizaveta Bovt, Elizaveta Bovt, Soslan Shakhidzhanov, Soslan Shakhidzhanov, Elena Sinauridze, Elena Sinauridze, Nataliya Smetanina, Larisa Koleva, Larisa Koleva, Nikita Kushnir, Nikita Kushnir, Anna Suvorova, Fazoil Ataullakhanov, Fazoil Ataullakhanov, Fazoil Ataullakhanov

“…Splenectomy does not correct most genetically determined membrane abnormalities in erythrocytes in patients with hereditary spherocytosis. …”
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Crop pangenomes by A. Yu. Pronozin, M. K. Bragina, E. A. Salina

“…These genomic variations play an important role in the functional set of genes and the gene composition in individuals of the same species and provide the genetic determination of the agronomically important crops properties. …”
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Complete Genomic Landscape Reveals Hidden Evolutionary History and Selection Signature in Asian Water Buffaloes (Bubalus bubalis) by Jingfang Si, Dongmei Dai, Neena Amatya Gorkhali, Mingshan Wang, Sheng Wang, Saroj Sapkota, Ram Chandra Kadel, Amir Sadaula, Aashish Dhakal, Md Omar Faruque, Abdullah Ibne Omar, Eka Meutia Sari, Hidayat Ashari, Muhammad Ihsan Andi Dagong, Marnoch Yindee, Hossam E. Rushdi, Hussein Elregalaty, Ahmed Amin, Mohamed A. Radwan, Lan Doan Pham, W. M. M. P. Hulugalla, G. L. L. Pradeepa Silva, Wei Zheng, Shahid Mansoor, Muhammad Basil Ali, Farhad Vahidi, Sahar Ahmed Al‐Bayatti, Alfredo Pauciullo, Johannes A. Lenstra, J. Stuart F. Barker, Lingzhao Fang, Dong‐Dong Wu, Jianlin Han, Yi Zhang

“…Abstract To identify the genetic determinants of domestication and productivity of Asian water buffaloes (Bubalus bubalis), 470 genomes of domesticated river and swamp buffaloes along with their putative ancestors, the wild water buffaloes (Bubalus arnee) are sequenced and integrated. …”
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Genomic Landscape Reveals Chromosomally-Mediated Antimicrobial Resistome and Virulome of a High-Risk International Clone II Acinetobacter baumannii AB073 from Thailand by Rattiya Cheewapat, Jadsadaporn Redkimned, Sirikran Lekuthai, Thawatchai Kitti, Kannipa Tasanapak, Aunchalee Thanwisai, Sutthirat Sitthisak, Thanet Sornda, Hathaichanok Impheng, Sudarat Onsurathum, Udomluk Leungtongkam, Supaporn Lamlertthon, Siriwat Kucharoenphaibul, Jintana Wongwigkarn, Pantira Singkum, Pattrarat Chanchaithong, Rapee Thummeepak

“…Likewise, mobilome analysis found that AB073 did not carry genetic determinants involving horizontal gene transfer. …”
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Genetic Predictors of Poor Prognosis in Portuguese Patients with Juvenile Idiopathic Arthritis: Data from Reuma.pt by Ana Filipa Mourão, Maria José Santos, Sílvia Mendonça, Filipa Oliveira-Ramos, Manuel Salgado, Paula Estanqueiro, José Melo-Gomes, Fernando Martins, Ana Lopes, Bruno Filipe Bettencourt, Jácome Bruges-Armas, José Costa, Carolina Furtado, Ricardo Figueira, Iva Brito, Jaime Branco, João Eurico Fonseca, Helena Canhão

“…This study aimed to assess the genetic determinants of poor outcome in Portuguese patients with juvenile idiopathic arthritis (JIA). …”
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Genetic Polymorphisms of Interleukin-1 Alpha and the Vitamin D Receptor in Mexican Mestizo Patients with Intervertebral Disc Degeneration by Salvador Cervin Serrano, Dalia González Villareal, Maribel Aguilar-Medina, Jose Guillermo Romero-Navarro, Jose Geovanni Romero Quintana, Eliakym Arámbula Meraz, Ignacio Osuna Ramírez, Veronica Picos-Cárdenas, Julio Granados, Iris Estrada-García, Guzman Sánchez-Schmitz, Rosalío Ramos-Payán

“…However, the development of this disease has strong genetic determinants. In this study, we explore the possible association between rs1800587 (c.-949C>T) of interleukin-1 alpha (IL1A) and rs2228570 (c.2T>V) and rs731236 (c.1056T>C) of vitamin D receptor (VDR) gene polymorphisms and the development of IDD in northwestern Mexican Mestizo population. …”
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A Dietary Treatment Improves Cerebral Blood Flow and Brain Connectivity in Aging apoE4 Mice by Maximilian Wiesmann, Valerio Zerbi, Diane Jansen, Roy Haast, Dieter Lütjohann, Laus M. Broersen, Arend Heerschap, Amanda J. Kiliaan

“…APOE ε4 (apoE4) polymorphism is the main genetic determinant of sporadic Alzheimer’s disease (AD). …”
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Inter- and intra-varietal clonal differences influence the aroma compound profiles of wines analyzed by GC–MS and GC-IMS by Huawei Chen, Shijian Bai, Bowei Yang, Ruihua Ren, Zizhu Tang, Zhenwen Zhang, Qingqing Zeng

“…These findings address the research gap concerning the genetic determinants of wine aroma, highlighting the significance of grape variety and clone selection in developing wines with desirable sensory attributes.…”
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The <i>OsGATA</i> gene family as a promising candidate for applying the CRISPR/Cas genome editing technology to improve the nutritional and yield qualities of rice (<i>Oryza sativa... by E. A. Nesterova, N. A. Shvachko

“…Living organisms manifest genetically determined responses to environmental factors, including stressors. …”
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Depression and Anxiety Disorders among Patients with Psoriasis: A Hospital-Based Case-Control Study by Masoud Golpour, Seyed Hamzeh Hosseini, Mohammad Khademloo, Maryam Ghasemi, Aghdas Ebadi, Fatemeh Koohkan, Soheila Shahmohammadi

“…Psoriasis is a common, genetically determined inflammatory and proliferative disease of the skin. …”
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Severe COVID-19 disease is associated with genetic factors affecting plasma ACE2 receptor and CRP concentrations by Verena Vogi, David Haschka, Lukas Forer, Simon Schwendinger, Verena Petzer, Stefan Coassin, Ivan Tancevski, Thomas Sonnweber, Judith Löffler-Ragg, Elisabeth Puchhammer-Stöckl, Marianne Graninger, Dominik Wolf, Florian Kronenberg, Johannes Zschocke, Emina Jukic, Günter Weiss

“…We suggest that genetically determined enforced CRP formation may contribute to strengthening of innate immune responses and better initial pathogen control thereby reducing the risk of subsequent hyperinflammation and adverse course of COVID-19.…”
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Data analysis of high-throughput sequencing and microarray to identify key signatures of microribonucleic acids in glioblastoma by A. A. Pushkin, E. A. Dzenkova, N. N. Timoshkina, D. Yu. Gvaldin

“…This research was devoted to study of mRNA and miRNA expression patterns in glioglastomas using The Cancer Genome Atlas (TCGA) data, to search for genetic determinants that determine the prognosis of patient survival and to create of interaction networks for glioblastomas.Materials and methods. …”
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Using Quantitative Trait Locus Mapping and Genomic Resources to Improve Breeding Precision in Peaches: Current Insights and Future Prospects by Umar Hayat, Cao Ke, Lirong Wang, Gengrui Zhu, Weichao Fang, Xinwei Wang, Changwen Chen, Yong Li, Jinlong Wu

“…Breeders now have access to precise tools that enhance crop resilience, productivity, and quality, facilitated by QTL mapping, which has significantly advanced our understanding of the genetic determinants underlying essential traits such as fruit shape, size, and firmness. …”
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Changes to Intermediary Metabolites in Sporadic and LRRK2 Parkinson’s Disease Demonstrated by Proton Magnetic Resonance Spectroscopy by Jan O. Aasly, Oddbjørn Sæther, Krisztina K. Johansen, Tone F. Bathen, Guro F. Giskeødegård, Linda R. White

“…Parkinson’s disease (PD) remains a clinical diagnosis and biomarkers are needed to detect the disease as early as possible. Genetically determined PD provides an opportunity for studying metabolic differences in connection with disease development. …”
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