Provocation of brachial plexus and systemic symptoms during the elevated arm stress test in individuals with myalgic encephalomyelitis/chronic fatigue syndrome or idiopathic chroni... by Charles C. Edwards, Julia M. Byrnes, Camille A. Broussard, Alba M. Azola, Meghan E. Swope, Colleen L. Marden, Renee L. Swope, Ying Wei Lum, Richard L. Violand, Peter C. Rowe

“…During EAST, 26/64 (41%) reported systemic symptoms (1 had only systemic but no upper limb symptoms), most commonly lightheadedness (19%) and generalized fatigue (11%). Conclusions Even with an abbreviated test duration, the EAST maneuver provoked local and systemic symptoms in a substantial proportion of patients with chronic fatigue, OI, and ME/CFS who had reported difficulty with arms-overhead postures. …”
Get full text

Shining light on knee osteoarthritis: an overview of vitamin D supplementation studies by Di Zhang, Miaoyu Ye, Yao Xu, Luyu Jiang, Yanmei Hu, Qi Zhang, Xiao Han, Qian Dai, Junhui Qian, Jian Luo, Qiang Yuan

“…Nevertheless, due to the generally low quality of current studies, future research should prioritize improving the quality of primary studies to establish the efficacy of vitamin D supplementation for KOA with more robust scientific evidence.Systematic review registrationThe protocol of this overview was registered in the International Prospective Register of Systematic Reviews (PROSPERO) (https://www.crd.york.ac.uk/PROSPERO/) with the registration number CRD42024535841.…”
Get full text

Research on the evolution and prediction of the heights of water-conducting fracture zones in overlying rocks during layered mining of extremely thick coal seams by MENG Hailun, CHENG Xianggang, QIAO Wei

“…As the working face continued to advance, the horizontal fractures within the overlying rock layers were compacted by the layer above, the fracture aperture decreased, and the fractal dimension gradually reduced. ③ During layered mining, the fractal dimension of fractures generally exhibited four stages: ascending dimension stage, dimension reduction stage, stationary stage, and fluctuating stage. ④ The PSO-SVR model was evaluated using indicators including mean absolute error (MAE), mean bias error (MBE), and correlation index R2. …”
Get full text

Wetland degradation monitoring using multi-temporal remote sensing data and watershed land degradation index by I. Ridwan, S. Kadir, N. Nurlina

“…(e) The rate of land degradation will generally increase from 2005 to 2020, with 2010 being the most extreme year.CONCLUSION: The proposed comprehensive land degradation index method is capable of describing the spatial and temporal aspect of land degradation from 2005 to 2020 in the watershed area. …”
Get full text

Administration of anticoagulation strategies for portal vein thrombosis in cirrhosis: network meta-analysis by Hui-Jun Li, Fu-Qiang Yin, Yu-Tong Ma, Teng-Yu Gao, Yu-Ting Tao, Xin Liu, Xian-Feng Shen, Chao Zhang

“…Heparin plus DOACs plus warfarin was recommended for reducing the occurrence of hepatic encephalopathy, and protocols that involve TIPS were generally associated with a higher risk of hepatic encephalopathy. …”
Get full text

The plasma metabolome of juvenile idiopathic arthritis varies according to subtype and underlying inflammatory status by Jooa Kwon, Melanie R. Neeland, Justine A. Ellis, Jane Munro, Richard Saffery, Boris Novakovic, Toby Mansell

“…There were no specific differences identified in oligoarticular (oJIA) or polyarticular (rheumatoid factor positive or negative) JIA relative to controls. Despite being generally highly correlated with hsCRP (r > 0.70), GlycA, but not hsCRP, was positively associated with active disease in sJIA (0.22, [-0.40, -0.04], P adj = 0.018), and 6 of 24 sJIA-associated markers were associated with GlycA levels. …”
Get full text

Smoking cessation is a protective factor for lung cancer onset and mortality: a population-based prospective cohort study by Wei Yin, Zhuochen Lin, Wei-Jie Gong, Wen-Xuan Wang, Ying-Ying Zhu, Yi-Lin Fu, Han Yang, Jin-Xin Zhang, Peng Lin, Ji-Bin Li

“…Methods A total of 2671 smokers with LC as the primary site from the UK Biobank were included in this study, with a 7:3 ratio assigned randomly to a discovery set (n = 1872) and a validation set (n = 799). Generalized linear regression models were used for AAO of LC outcomes and Cox models for mortality outcomes. …”
Get full text

Co-benefits of nature-based solutions: A health impact assessment of the Barcelona Green Corridor (Eixos Verds) plan by Tamara Iungman, Sergi Ventura Caballé, Ricard Segura-Barrero, Marta Cirach, Natalie Mueller, Carolyn Daher, Gara Villalba, Evelise Pereira Barboza, Mark Nieuwenhuijsen

“…We computed the percentage increase in GS (land use) and tree cover and converted them into Normalized Difference Vegetation Index (NDVI) to conduct the HIA, employing a Generalized Additive Model (GAM). We used the Weather Research and Forecasting model (WRF) coupled with the urban parameterizations “Building Effect Parameterization” (BEP) and “Building Energy Model” (BEM) for temperature modelling. …”
Get full text

Association between chronic obstructive pulmonary disease and osteoporosis: Mendelian randomization combined with bibliometric analysis by Fangjun Yang, Huaming Wang, Miaomiao Liu, Shengtai Pei, Xiaoming Qiu

“…The results of the primary IVW MR Analysis were generally supported by our sensitivity MR Analysis. …”
Get full text

Low-activity [18F]-somatostatin receptor (SSTR) imaging using [18F]SiTATE on a long axial field-of-view PET/CT scanner by Nils F. Trautwein, Eduardo Calderón, Pia M. Linder, Gerald Reischl, Philippe Driessen, Wenhong Lan, Andreas S. Brendlin, Thorben Groß, Helmut Dittmann, Martina Hinterleitner, Christian la Fougère, Fabian P. Schmidt, Lena S. Kiefer

“…Results Subjective image quality decreased with simulated reduction of injected activity with generally superior ratings in the UHS mode compared to the HS mode. …”
Get full text

Dual-Stage AI Model for Enhanced CT Imaging: Precision Segmentation of Kidney and Tumors by Nalan Karunanayake, Lin Lu, Hao Yang, Pengfei Geng, Oguz Akin, Helena Furberg, Lawrence H. Schwartz, Binsheng Zhao

“…Conclusions: The proposed model demonstrates consistent and robust performance in segmenting kidneys and kidney tumors of various sizes, with effective generalization to unseen data. This underscores the model’s significant potential for clinical integration, offering enhanced diagnostic precision and reliability in radiological assessments.…”
Get full text

Effect of motivational interviewing to promote advance care planning among palliative care patients in ambulatory care setting: a randomized controlled trial by Helen Yue-Lai Chan, Doris Yin-Ping Leung, Po-Tin Lam, Polly Po-Shan Ko, Raymond Wai-Man Lam, Kin-Shan Chan

“…Results A total of 204 participants (mean [SD] age, 74.9 [10.8]; 64.7% male; 80.4% cancer) were recruited. Generalized estimating equation analyses showed a significant improvement in readiness for advance care planning behaviors in the intervention group compared with the control group at 3 months post-allocation (group-by-time interaction, appointing proxy: β = 0.80; 95% CI, 0.25–1.35; p = .005; discussing with family: β = 0.76; 95% CI, 0.22–1.31; p = .006; discussing with medical doctors: β = 0.86; 95% CI, 0.30–1.42; p = .003; documenting: β = 0.89; 95% CI, 0.36–1.41; p < .001). …”
Get full text

Changes in Physical Activity Across Cancer Diagnosis and Treatment Based on Smartphone Step Count Data Linked to a Japanese Claims Database: Retrospective Cohort Study by Yoshihide Inayama, Ken Yamaguchi, Kayoko Mizuno, Sachiko Tanaka-Mizuno, Ayami Koike, Nozomi Higashiyama, Mana Taki, Koji Yamanoi, Ryusuke Murakami, Junzo Hamanishi, Satomi Yoshida, Masaki Mandai, Koji Kawakami

“…The observation period spanned from 6 months before diagnosis to 12 months after diagnosis. We applied a generalized additive mixed model with a cubic spline to describe changes in step counts before and after diagnosis. …”
Get full text

Adjuvant-free, self−assembling ferritin nanoparticle vaccine coupled with influenza virus hemagglutinin protein carrying M1 and PADRE epitopes elicits cross-protective immune respo... by Yongqiang Zhao, Shuangshuang Guo, Jia Liu, Yating Wang, Bo Wang, Chun Peng, Enqi Du, Enqi Du, Enqi Du

“…Current influenza virus vaccines generally provide strain-specific protection and must be rapidly produced annually to match the circulating viruses. …”
Get full text

Interaction study of the effects of environmental exposure and gene polymorphisms of inflammatory and immune-active factors on chronic obstructive pulmonary disease by Rui Wang, Yuanyuan Li, Yuting Jiang, Xiaona Liu, Hongqi Feng, Zhe Jiao, Bingyun Li, Chang Liu, Yuncheng Shen, Fang Chu, Chenpeng Zhu, Dianjun Sun, Wei Zhang

“…Logistic regression model, generalized multifactor dimensionality reduction and crossover analysis were used to analyse the effects of SNPs, gene–gene interactions, and gene-environment interactions on COPD. …”
Get full text

Burden of chronic obstructive pulmonary disease attributable to ambient ozone pollution across China and its provinces, 1990–2021: An analysis for the Global Burden of Disease Stud... by Yixuan Jiang, Fanshu Yan, Haidong Kan, Maigeng Zhou, Peng Yin, Renjie Chen, Jing Ni

“…In 2021, a total of 125.7 (95% uncertainty interval [UI], 26.4–228.3) thousand deaths and 1917.5 (95% UI, 398.7–3504.6) thousand DALYs from COPD were attributable to ambient O3 pollution in China, accounting for 9.8% (95% UI, 2.1–17.0%) and 8.1% (95% UI, 1.8–14.1%) of the total COPD deaths and DALYs, respectively. Generally, a higher burden was observed among males, the elderly, and the population residing in regions with worse health conditions. …”
Get full text

The effects of PM2.5 components on the cardiovascular disease admissions in Shanghai City, China: a multi- region study by Wanying Su, Heping Liu, Tiantian Han, Yunyun Wang, Yi An, Yan Lin

“…We obtained CVD daily admissions data from relevant departments of Tongji Hospital, including basic information (sex, age, time of admissions, ICD code of root cause of admissions, etc.). First, generalized additive model (GAM) and distributed lag non-linear (DLNM) model were used to evaluate the individual effects of PM2.5 components on CVD admission in three districts of Shanghai. …”
Get full text

An analytical cross-sectional study on optimal (timely or cumulative age-appropriate) routine childhood immunization coverage in the communities of Ebonyi state, Nigeria by Ugwu I. Omale, Cordis O. Ikegwuonu, Glory E. Nkwo, Chimaobi C. Iwegbulam, Louisa C. Ekwuazi, Chidinma I. Amuzie, Richard L. Ewah

“…Descriptive analysis and multivariate generalized estimating equations were carried out. Of 1262 children aged 5–11 months, 8.6% had optimal (timely or cumulative age-appropriate) receipt of every recommended birth to 14 weeks vaccine (this was 18.3% of the 596 who had received every recommended vaccine dose) and the median (IQR) receipt timeliness (age-appropriate vaccines receipt) score for the recommended birth to 14 weeks vaccines by these children was 79.3 (64.9–91.7). …”
Get full text

Technical note: “U–Th Analysis” – open-source software dedicated to MC-ICP-MS U-series data treatment and evaluation by I. K. Kerber, F. Kontor, A. Mielke, A. Mielke, S. Warken, S. Warken, N. Frank

“…We demonstrate the relevance of adequate data outlier treatment and generally recommend using the median instead of the mean of calculated ratios. …”
Get full text

Industry of employment and occupational class in relation to cardiovascular health by race/ethnicity, sex/gender, age and income among adults in the USA: a cross-sectional study by Symielle A Gaston, Chandra L Jackson, Jamie A Murkey, Dana M Alhasan, W Braxton Jackson

“…Background Racially minoritised groups tend to have poorer cardiovascular health (CVH) than non-Hispanic (NH)-White adults and are generally more likely to work in labourer or support service positions where job strain—associated with cardiovascular disease—is often high. …”
Get full text