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Deciphering the generation of heterogeneity in esophageal squamous cell carcinoma metastasis via single-cell multiomics analysis
Published 2025-02-01Subjects: Get full text
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Multi-locus CRISPRi targeting with a single truncated guide RNA
Published 2025-02-01Get full text
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In Vitro Screening and Transfection Concentration Optimization of Cynomolgus Monkey IκBα-siRNA
Published 2020-01-01Get full text
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CXCR4 promotes tumor stemness maintenance and CDK4/6 inhibitors resistance in ER-positive breast cancer
Published 2025-01-01Get full text
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Drug Target Identification and Prioritization for Treatment of Ovine Foot Rot: An In Silico Approach
Published 2016-01-01Get full text
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EpigenomeViewer: A Shiny Web Application for Visualizing Methylation Patterns Across Biological Samples
Published 2025-02-01“…DNA methylation plays a crucial role in gene regulation and is involved in the development of numerous diseases including cancer. …”
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Sex and gender differences in the molecular etiology of Parkinson’s disease: considerations for study design and data analysis
Published 2025-02-01“…In this review, we summarize known contributors to sex differences in PD etiology across the life course, with a focus on neurological development and gene regulation. Sex differences that are established at conception and heightened during adolescence and midlife may partially embed future PD risk, due to the complex interactions between gonadal hormones, gene regulation, lifestyle factors, and aging. …”
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Control of Cellular Differentiation Trajectories for Cancer Reversion
Published 2025-01-01“…Abstract Cellular differentiation is controlled by intricate layers of gene regulation, involving the modulation of gene expression by various transcriptional regulators. …”
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The Emerging Role of Mesenchymal Stem Cells in Vascular Calcification
Published 2019-01-01Get full text
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Genetics : analysis of genes and genomes /
Published 2019Table of Contents: “…Genes, genomes and genetic analysis -- DNA structure and genetic variation -- Transmission genetics : the principle of segregation -- The chromosomal basis of inheritance -- Genetic linkage and chromosome mapping -- Human karyotypes and chromosome behavior -- The genetics of complex characters -- Genetics of the bacteria and their viruses -- Molecular organization of chromosomes and genomes -- DNA replication and sequencing -- Mutation, repair, and recombination -- Molecular biology of gene expression -- Molecular mechanisms of gene regulation -- Manipulating genes and genomes -- Genetic control of development -- The genetics of cancer -- Extranuclear inheritance -- Genetics of populations -- Human evolution.…”
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Messenger RNA in differentiating muscle cells—my experience in François Gros’ lab in the 1970s and 80s
Published 2023-12-01“…In the early 1970s, it was the beginning of research in his lab on muscle cell differentiation, as a model eukaryotic system for studying mRNAs and gene regulation. In this article, I recount our work on myogenesis and mention the other research themes in his lab and the people concerned. …”
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Micro-RNA Expression and Function in Lymphomas
Published 2011-01-01“…The recent discovery of microRNAs (miRNAs) has introduced a new layer of complexity to the process of gene regulation. MiRNAs are essential for cellular function, and their dysregulation often results in disease. …”
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