Vitamin D Receptor Gene Polymorphisms Influence T1D Susceptibility among Pakistanis by Maryam Mukhtar, Andleeb Batool, Abdul Wajid, Iram Qayyum

“…The vitamin D receptor (VDR) gene regulates insulin secretion from the pancreas and acts as a mediator of the immune response through vitamin D. …”
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MicroRNA-219 in the central nervous system: a potential theranostic approach by Nahal Shamaeizadeh, Mina Mirian

“…Micro ribonucleic acid (microRNA-miRNA), as a fundamental gene regulator, regulates messenger ribonucleic acid (mRNA) by directly binding through the 3′-untranslated region (3′-UTR). …”
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Constipation at endocrine diseases by Yu. O. Shulpekova, A. G. Komova

“…Constipation is one of broad spectrum of gastro-intestinal hyperthyroidism manifestations, probably, related to change in expression of the genes regulating motility, decrease of autonomous nervous system excitability and dehydration. …”
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Cereal inflorescence: features of morphology, development and genetic regulation of morphogenesis by O. B. Dobrovolskaya, A. E. Dresvyannikova

“…The genes involved in the control of the cereal inflorescence development have been identified using mutants (mainly maize and rice) with altered inflorescence and floret morphology; most of these genes regulate the initiation and fate of meristems. The presence of some genetic mechanisms in cereals confirms the models previously discovered in dicotyledonous plants; on the other hand, there are cereal-specific developmental processes that are controlled by new modules of genetic regulation, in particular, associated with the formation of a branched inflorescence. …”
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Role of the two-component system AmgRS in early resistance of Pseudomonas aeruginosa to cinnamaldehyde by Eline Dubois, Vladimir Spasovski, Patrick Plésiat, Catherine Llanes

“…In this study, we demonstrate that CNA exposure induces expression of genes regulated by the two-component system AmgRS. AmgRS activates MexAB-OprM production, independent of repressors MexR and NalD. …”
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Identification of KRT16 and ANXA10 as cell cycle regulation genes for lung adenocarcinoma based on self-transcriptome sequencing of surgical samples and TCGA public data mining by Wen-jian Liu, Jia-pan Shen, Ren-quan Zhang, Xiao-yun Fan

“…Conclusions KRT16 and ANXA10 are potential genes regulating the development of LUAD. Also, they may be potential targets for the targeted therapy of LUAD by inhibiting the proliferation of lung cancer cells and blocking the cell cycle by affecting key protein expression levels at cell cycle checkpoints.…”
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Genetics of aging and longevity by A. A. Moskalev, E. N. Proshkina, A. A. Belyi, I. A. Solovyev

“…Based on the analysis of geroprotective potential of examined genes’ regulation, main targets have been identified to slowdown aging and achieve healthy longevity. …”
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Effects of exogenous insulin supplementation on lipid metabolism in peripartum obese dairy cows by Yuanyin Guo, Yihan Zhao, Ziang Wei, Jie Cao

“…In this study, we assessed the effects of exogenous insulin supplementation on lipid metabolism, key genes regulated by insulin, and the underlying regulatory mechanism. …”
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Using achievements of fruit crop genetics and breeding: a contribution from the Michurinsk Department of the Vavilov Society of Geneticists and Breeders by N. I. Savel’ev, N. N. Savel’eva

“…Some genes were identified for the first time. These are genes regulating Coccomyces hiemalis Higg. resistance (A), retarded growth habit in cherry (O2), astringency (Ta) and juiciness (Su) of fruit in pear. …”
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Integrative pan-cancer analysis and experiment validation identified GLS as a biomarker in tumor progression, prognosis, immune microenvironment, and immunotherapy by Dongming Li, Donghui Cao, Yangyu Zhang, Xinyi Yu, Yanhua Wu, Zhifang Jia, Jing Jiang, Xueyuan Cao

“…Abstract Glutaminase (GLS), a crucial gene regulating glutaminolysis, has received much attention as it was found to regulate tumor metabolism and copper-induced cell death. …”
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Reconstruction and analysis of the gene regulatory network for cell wall function in <i>Arabidopsis thaliana</i> L. leaves in response to water deficit by A. R. Volyanskaya, E. A. Antropova, U. S. Zubairova, P. S. Demenkov, A. S. Venzel, Y. L. Orlov, A. A. Makarova, T. V. Ivanisenko, T. A. Gorshkova, A. R. Aglyamova, N. A. Kolchanov, M. Chen, V. A.  Ivanisenko

“…The analysis of the gene network and the transcriptome data analysis allowed prioritizing transcription factors (TF) based on their enrichment of differentially expressed genes regulated by them. As a result, scores were calculated, acting as indicators of the association of TFs with water deficit. …”
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Cooperative mechanisms of LexA and HtpG in the regulation of virulence gene expression in Pseudomonas plecoglossicida by Rongchao He, Yanfei Zuo, Qiu Li, Qingpi Yan, Lixing Huang

“…Our findings identified 36 downstream virulence genes regulated by LexA, define three critical LexA binding motifs, and provide an in-depth analysis of LexA's recognition and binding to promoters, thereby regulating virulence gene expression. …”
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Anaerobic metabolism promotes breast cancer survival via Histone-3 Lysine-18 lactylation mediating PPARD axis by Ying Xu, Weiwei Meng, Yingqi Dai, Lin Xu, Ning Ding, Jinqing Zhang, Xuewei Zhuang

“…We utilized chromatin immunoprecipitation sequencing with H3K18la antibodies, transcriptomics of clinical BC samples, and proteomics and ATAC-seq analyses of in vivo tumors to identify the genes regulated by H3K18la and the transcription factor PPARD. qPCR and Western blot assays were used to detect expressions of molecules. …”
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Physiological and molecular mechanisms of exogenous salicylic acid in enhancing salt tolerance in tobacco seedlings by regulating antioxidant defence system and gene expression by Xiliang Song, Jian Chen, Can Xu, Xianjie Cai, Wenjing Song, Aixia Chang, Yu Zhang, Chenggang Luo

“…Exogenous SA also increased ascorbate and glutathione levels and reduced their reduced forms by increasing the activities of glutathione reductase, ascorbate peroxidase, monodehydroascorbate reductase and dehydroascorbate reductase. qRT−PCR analysis revealed that the key genes regulating SA biosynthesis, carbon assimilation, the antioxidant system and the ascorbate−glutathione cycle were activated by SA under conditions of salt stress.DiscussionOur study elucidates the physiological and molecular mechanisms of exogenous SA in enhancing plant salt tolerance and provides a practical basis for crop improvement in saline environments.…”
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Identification of Candidate Genes for Green Rind Color in Watermelon by Wei Zhou, Licong Yi, Yunqiang Wang, Hongsheng Wang, Qingke Li, Na Wu, Zhaoyi Dai

“…Its genetic analysis was conducted to provide the identification of genes regulating rind color and improving the quality of watermelon appearance. …”
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Potential Candidate Genes Associated with Litter Size in Goats: A Review by Wenting Chen, Ying Han, Yinghui Chen, Xiaotong Liu, Huili Liang, Changfa Wang, Muhammad Zahoor Khan

“…Recent advancements in genetic research have identified key genes and pathways associated with reproductive traits, including gonadotropin-releasing hormone (<i>GnRH</i>), inhibin (<i>INHAA</i>), Kit ligand (<i>KITLG</i>), protein phosphatase 3 catalytic subunit alpha (<i>PPP3CA</i>), prolactin receptor (<i>PRLR</i>), POU domain class 1 transcription factor 1 (<i>POU1F1</i>), anti-Müllerian hormone (<i>AMH</i>), bone morphogenetic proteins (<i>BMP</i>), growth differentiation factor 9 (<i>GDF9</i>), and <i>KISS1</i> and suppressor of mothers against decapentaplegic (<i>SMAD</i>) family genes, among others. These genes regulate crucial physiological processes such as folliculogenesis, hormone synthesis, and ovulation. …”
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Modulation of Stemness and Differentiation Regulators by Valproic Acid in Medulloblastoma Neurospheres by Natália Hogetop Freire, Alice Laschuk Herlinger, Julia Vanini, Matheus Dalmolin, Marcelo A. C. Fernandes, Carolina Nör, Vijay Ramaswamy, Caroline Brunetto de Farias, André Tesainer Brunetto, Algemir Lunardi Brunetto, Lauro José Gregianin, Mariane da Cunha Jaeger, Michael D. Taylor, Rafael Roesler

“…VPA increased H3K9 occupancy of the promoter region of <i>TP53</i>. Among the genes regulated by VPA, the stemness regulators <i>MYC</i> and <i>NES</i> showed an association with patient survival in specific MB subgroups. …”
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Transcriptome and DNA methylation analysis of the goat pineal gland during puberty by Bochao Zhang, Genbao Zhu, Jianling Wu, Huihui Xie, Jiankun Cui, Wei Qian, Qing Yi, Fuqiang Pan, Fugui Fang, Yinghui Ling, Yunhai Zhang, Yunsheng Li, Ya Liu

“…Changes in DNA methylation patterns affected some pineal gland transcriptomes, while the transcriptional level of most genes remained unaffected by DNA methylation differences. Genes regulated by DNA methylation regulates genes primarily involved in metabolic processes, oxidative phosphorylation, and signaling pathways related to thermogenesis. …”
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Genome-Wide Identification and Expression Analysis of Eggplant Reveals the Key MYB Transcription Factor Involved in Anthocyanin Synthesis by Jiaqi Ai, Wuhong Wang, Tianhua Hu, Haijiao Hu, Yaqin Yan, Jinglei Wang, Yunzhu Wang, Na Hu, Hongtao Pang, Chonglai Bao, Qingzhen Wei

“…Furthermore, 10 MYB TFs were identified as potential genes regulating anthocyanin synthesis in different tissues. …”
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Developmental deficits, synapse and dendritic abnormalities in a Clcn4 KO autism mice model: endophenotypic target for ASD by Seong Mi Lee, Yura Choi, Dayeon Kim, Ha Jin Jeong, Young Ho Do, Sohee Jung, Bomee Lee, Hyung Jun Choi, Suhyeon Kim, Jung-Min Oh, Songhee Jeon, Jinju Han, Yeni Kim

“…RNA sequencing data from mouse neural progenitor cells (mNPCs) showed that the genes regulating trans-synaptic signaling, transmembrane transport, and neuronal projection development were significantly decreased in Clcn4 knockdown (KD) cells compared to wild type (WT). …”
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