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1921
Novel molecular biomarkers of cancer therapy‐induced cardiotoxicity in adult population: a scoping review
Published 2022-06-01“…Fourteen studies reported 44 new protein biomarkers, 18 studies reported 57 new single nucleotide polymorphism biomarkers, and 11 studies reported 171 new gene expression profiles associated with cardiotoxicity. …”
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1922
Skeletal Muscle-Derived Stem/Progenitor Cells: A Potential Strategy for the Treatment of Acute Kidney Injury
Published 2016-01-01“…MDSPCs exhibited similar immunophenotype, stem cell gene expression, and multilineage differentiation capacities as BM-MSCs, but they demonstrated higher proliferation rate. …”
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1923
Identification and functional analysis of energy metabolism and pyroptosis-related genes in diabetic nephropathy
Published 2025-02-01“…Methods: EMAPRDEGs were identified by querying the GeneCards and Gene Expression Omnibus (GEO) databases. Subsequent analyses included Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment, Gene Set Enrichment Analysis (GSEA), and Protein-Protein Interaction (PPI) network analysis. …”
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1924
Effects of Novaluron Exposure on the Oviposition and Expression of Ovarian Development Related Genes in Silkworm, <i>Bombyx mori</i> (Lepidoptera: Bombycidae)
Published 2024-12-01“…In this study, the effect of trace novaluron on the oviposition of silkworms and histopathological changes were first evaluated, and then the gene expression level changes after novaluron exposure were also determined by employing qRT-PCR. …”
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1925
Integrated analysis of the transcriptome and hormone metabolome elucidates the regulatory mechanisms governing walnut bud germination
Published 2025-01-01“…By assessing hormone levels and gene expression at different developmental stages, we pinpointed potential regulatory genes and critical hormones associated with bud germination. …”
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1926
Mechanistic elucidation of human pancreatic acinar development using single-cell transcriptome analysis on a human iPSC differentiation model
Published 2025-02-01“…Furthermore, differential gene expression analysis revealed upregulated pathways, including cAMP-related signals, involved in the differentiation of hiPSC-derived pancreatic acinar lineage cells in vivo, and we found that a cAMP activator, forskolin, facilitates the differentiation from hiPSC-derived pancreatic endoderm into pancreatic acinar progenitor cells in our in vitro differentiation culture. …”
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1927
Does Adiponectin Act as an Antiangiogenic Factor in B-Cell Chronic Lymphocytic Leukemia?
Published 2009-01-01“…Finally, we evaluated the presence of adiponectin in B-CLL cells at gene expression level. RMA intensity values for adiponectin gene transcript denote a homogeneous low expression in B-CLL cells, whereas VEGF transcript was highly expressed with a degree of interpatient variability. …”
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1928
Cecal Patches Generate Abundant IgG2b-Bearing B Cells That Are Reactive to Commensal Microbiota
Published 2022-01-01“…In this study, we demonstrate that the CePs possess more IgG2b+ B cells and have fewer IgA+ B cells than those in PPs from BALB/c mice with normal gut microbiota. Gene expression analysis of postswitched transcripts supported the differential expression of dominant antibody isotypes in B cells in GALT. …”
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1929
Intestinal Organoids in Colitis Research: Focusing on Variability and Cryopreservation
Published 2021-01-01“…First, to analyze the impact of antibiotics/antimycotics, we performed kinetic experiments using ZellShield® and measured the gene expression levels of the tight junction markers Ocln, Zo-1, and Cldn4, the proliferation marker Ki67, and the proinflammatory cytokine Tnfα. …”
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1930
Early embryonic thermal programming and post-hatch flavonoid (Scutellaria baicalensis) supplementation enhanced immune response markers in broiler chickens
Published 2025-01-01“…When combined with baicalein, TM mitigated the negative effects of heat stress by boosting key immune-related gene expression in the spleen, bursa, and thymus.…”
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1931
DHX37 Impacts Prognosis of Hepatocellular Carcinoma and Lung Adenocarcinoma through Immune Infiltration
Published 2020-01-01“…Confirming the prognostic value of DHX37 in liver hepatocellular carcinoma (LIHC) and lung adenocarcinoma (LUAD), we explored the role of DHX37 in infiltrated lymphocytes in cancers using the Gene Expression Profiling Interactive Analysis (GEPIA) and TIMER databases. …”
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1932
Modulated Light Elicitation and Associated Physiological and Molecular Processes in Phenolic Compounds Production in <i>Ocimum basilicum</i> L. Microgreens
Published 2025-01-01“…Moreover, in the red cultivar, gene expression was enhanced, 1.3–6.3 fold for genes coding for enzymes involved in phenylpropanoid synthesis pathways, such as phenylalanine ammonia lyase (PAL), tyrosine aminotransferase (TAT), Catechol-O-methyltransferase (COMT) and rosmarinic acid synthetase (RAS). …”
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1933
The Effects of Hyperacute Serum on the Elements of the Human Subchondral Bone Marrow Niche
Published 2018-01-01“…Viability measurements, RT-qPCR evaluation for gene expression and flow cytometry for cell surface marker analysis were performed to compare the effects of FCS-, PRP-, or HAS-supplemented culture media. …”
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1934
Identification of Potential Biomarkers and Immune Features of Sepsis Using Bioinformatics Analysis
Published 2020-01-01“…Three datasets (GSE95233, GSE57065, and GSE28750) associated with sepsis were downloaded from the public functional genomics data repository Gene Expression Omnibus. Differentially expressed genes (DEGs) were identified using R packages (Affy and limma). …”
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1935
Creating burdock polysaccharide-oleanolic acid-ursolic acid nanoparticles to deliver enhanced anti-inflammatory effects: fabrication, structural characterization and property evalu...
Published 2023-03-01“…Compared with ALPs, ALP-OA/UA nanoparticles showed enhanced anti-inflammatory activity (especially at a dose of 100 μg/mL) in a CuSO4-induced zebrafish inflammation model via down-regulating the NF-κB signalling pathway and gene expression of associated transcription factors and cytokines (TNF-α, IL-1β and IL-8). …”
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1936
Identification of Heat-Responsive Genes in Guar [Cyamopsis tetragonoloba (L.) Taub]
Published 2020-01-01“…In the current study, the differential gene expression and the underlying metabolic pathways induced by heat treatment were investigated. …”
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1937
Novel immune cross-talk between inflammatory bowel disease and IgA nephropathy
Published 2024-12-01“…The IgAN and IBD datasets were obtained from the Gene Expression Omnibus (GEO). Three algorithms, CIBERSORTx, ssGSEA, and xCell, were used to evaluate the similarities in the infiltrating microenvironment between the two diseases. …”
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1938
Pharmacological effects of fibroblast growth factor 21 are sex-specific in mice with the <em>lethal yellow</em> (A<sup>y</sup>) mutation
Published 2020-04-01“…Food intake (FI), body weight (BW), blood parameters, and gene expression in the liver, muscles, brown adipose tissue, subcutaneous and visceral white adipose tissues, and hypothalamus were measured. …”
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1939
Uncovering the role of microRNAs in esophageal cancer: from pathogenesis to clinical applications
Published 2025-01-01“…Recently, microRNAs (miRNAs) have attracted significant attention for their capacity to regulate gene expression at the post-transcriptional level, thereby influencing various cellular processes. …”
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1940
Immunoglobulin M response in largemouth bass (Micropterus salmoides) following ranavirus infection
Published 2025-01-01“…Our findings revealed that viral infection caused significant pathological changes in the gill and head kidney tissues, along with a marked upregulation of adaptive immune gene expression. Interestingly, fish that survived an initial viral infection exhibited minimal mortality and low viral loads in the gill and head kidney tissues when exposed to a higher viral concentration. …”
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