Object-Place Recognition Learning Triggers Rapid Induction of Plasticity-Related Immediate Early Genes and Synaptic Proteins in the Rat Dentate Gyrus by Jonathan Soulé, Zsuzsa Penke, Tambudzai Kanhema, Maria Nordheim Alme, Serge Laroche, Clive R. Bramham

“…In situ hybridization and immunohistochemistry were therefore used to assess possible sparse effects on gene expression. Learning about objects increased the density of granule cells expressing Arc, and to a lesser extent Narp, specifically in the dorsal blade of the dentate gyrus, while Zif268 expression was elevated across both blades. …”
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TEC-mediated tRF-31R9J regulates histone lactylation and acetylation by HDAC1 to suppress hepatocyte ferroptosis and improve non-alcoholic steatohepatitis by Juanjuan Zhu, Xian Wu, Mao Mu, Quan Zhang, Xueke Zhao

“…Mechanistically, tRF-31R9J recruited HDAC1 to reduce the levels of histone lactylation and acetylation modifications of the pro-ferroptosis genes ATF3, ATF4, and CHAC1, thereby inhibiting their gene expression. Conclusions This study demonstrates that TEC-mediated tRF-31R9J inhibits hepatocyte ferroptosis through HDAC1-regulated histone delactylation and deacetylation, thereby improving NASH. …”
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Acinetobacter baumannii Lipopolysaccharide Influences Adipokine Expression in 3T3-L1 Adipocytes by Yuka Unno, Yoshinori Sato, Satoshi Nishida, Akiyo Nakano, Ryuichi Nakano, Tsuneyuki Ubagai, Yasuo Ono

“…This study suggests that A. baumannii-derived LPS functions as a signaling molecule that impacts the inflammatory function of white adipose tissue on the level of gene expression.…”
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Tailoring microbial redox with alternating current for efficient mineralization of refractory organic nitrogen compounds in wastewater by Ye Yuan, Xucui Qian, Lulu Zhang, Wanxin Yin, Tianming Chen, Zhaoxia Li, Cheng Ding, Bo Wang, Bin Liang, Aijie Wang, Yang Liu, Fan Chen

“…Multi-omics analysis shows enrichment of functional microbial consortia involved in NB reduction, aromatic compound oxidation, ammonia oxidation, nitrate/nitrite reduction, and electron transfer, with upregulated enzyme gene expression. Carbon metabolites from catechol meta-cleavage support nitro-reduction, denitrification, and cell viability without external carbon sources. …”
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Physiological and transcriptome analysis of sex-specific responses to cadmium stress in poplars by Meihua Liu, Sumei Wu, Yigang Song, Mengjiao Shi, Lita Yi

“…Sex-specific responses to Cd were associated with differential gene expression. Under Cd stress, the genes related to oxidation-reduction processes, antioxidant enzyme activity and defense mechanisms, cell wall synthesis, and glutathione metabolism were mainly enriched and upregulated in females, whereas in males, genes related to photosynthesis and photosynthetic pigment biosynthesis were mainly enriched and downregulated, indicating greater damage to the photosynthetic system than in females. …”
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Generation of American mink induced pluripotent stem cells: a protocol by I. E. Pristyazhnyuk, A. G. Menzorov

“…In 2015 we produced American mink iPS cells and showed fibro-blast genome reprogramming at the level of gene expression and divided genes into four groups: reprogrammed, with intermediate expression, non-reprogrammed, and the ones with a “novel” expression pattern. …”
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BMI1, ALDH1A1, and CD133 Transcripts Connect Epithelial-Mesenchymal Transition to Cancer Stem Cells in Lung Carcinoma by Ana Koren, Matija Rijavec, Izidor Kern, Eva Sodja, Peter Korosec, Tanja Cufer

“…The immunohistochemical analysis confirmed coexpression of BMI1 and CSC markers in tumors. Gene expression profiling in CTCs revealed upregulated expression of EMT/CSC markers in CTCs. …”
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Transcutaneous Electrical Acupoint Stimulation in Early Life Changes Synaptic Plasticity and Improves Symptoms in a Valproic Acid-Induced Rat Model of Autism by Xiaoxi Wang, Rui Ding, Yayue Song, Juan Wang, Chen Zhang, Songping Han, Jisheng Han, Rong Zhang

“…Results of the transcriptomic study showed that expression of some transcription factors such as the neurotrophic factor were downregulated in the hypothalamus of the VPA model of ASD. The reduced gene expression was reversed following TEAS. These results suggest that TEAS in the early life stage may mitigate disorders of social and recognition ability and normalize the pain threshold of the ASD rat model. …”
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Shallow-water mussels (Mytilus galloprovincialis) adapt to deep-sea environment through transcriptomic and metagenomic insights by Luyang Sun, Xiaolu Liu, Li Zhou, Hao Wang, Chao Lian, Zhaoshan Zhong, Minxiao Wang, Hao Chen, Chaolun Li

“…Results reveal complex gene expression adjustments in stress response, immune defense, homeostasis, and energy metabolism pathways during adaptation. …”
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Treatment of Radiation Bone Injury with Transplanted hUCB-MSCs via Wnt/β-Catenin by Yufeng Zhang, Huaxin Deng, Zhiqiang Yang, Zhe Chen, Sheng Zhang, Yufan Zhu, Min Yang, Houcheng Zhong, Fuling Zhou, Yuanlong Xie, Lin Cai

“…Western blot analysis, qRT-PCR, immunohistochemistry, and immunofluorescence staining were used to analyze gene expression and angiogenesis. The apoptosis and migration of osteoblasts were measured by Hoechst staining, scratch test, and transwell. …”
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Molecular Characterization and Expression of <i>unc-13d</i> in the Sex Reversal of <i>Monopterus albus</i> by Zitong Lian, Fang Meng, Xueping Xia, Junchao Fang, Haifeng Tian, Qiaomu Hu

“…We found that the promoter methylation of <i>unc-13d</i> was negatively correlated with gene expression in developing gonads, especially at site 114. …”
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Aging restricts the initial neural patterning potential of developing neural stem and progenitor cells in the adult brain by Saeideh Aran, Mohammad Ghasem Golmohammadi, Mohsen Sagha, Kamran Ghaedi

“…Finally, it was assessed the effect of cell attachment and passage on the initial neural patterning of NSPCs.ResultsThe analysis of gene expression revealed that although temporal patterning is maintained in vitro, it shows a decrease over time. …”
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Exosome-Associated Gene Signature for Predicting the Prognosis of Ovarian Cancer Patients by Zihan Zhu, Rui Geng, Yixin Zhang, Jinhui Liu, Jianling Bai

“…We discovered that resting dendritic cells and stromal scores were upregulated in patients with high risk in the TCGA and Gene Expression Omnibus (GEO) cohorts. Moreover, the expression of six common immune checkpoint inhibitor targets was assessed, which revealed that the expression levels of CD274 (PD-L1), PDCD1 (PD-1), and IDO1 in patients with high risk were lower than those in patients with low risk. …”
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Chitosan-DNA nanoparticles: synthesis and optimization for long-term storage and effective delivery by Aigul Raimbekova, Ulpan Kart, Akbayan Yerishova, Timur Elebessov, Sergey Yegorov, Tri Thanh Pham, Gonzalo Hortelano

“…Confocal microscopy was used to visualize post-transfection gene expression. Time, volume, and effect of sonication were tested to optimize the lyophilization process. …”
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Acute Leukemia Induces Senescence and Impaired Osteogenic Differentiation in Mesenchymal Stem Cells Endowing Leukemic Cells with Functional Advantages by Ximena Bonilla, Natalia-Del Pilar Vanegas, Jean Paul Vernot

“…We found that leukemic cells induced in MSC a significant increase both in senescence-associated β-galactosidase activity and in p53 gene expression. MSC in the LN also showed a persistent production of cytoplasmic reactive oxygen species (ROS) and a G2/M phase arrest of the cell cycle. …”
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Isolation of <i>Bacillus paralichenifromis</i> BL-1 and Its Potential Application in Producing Bioflocculants Using Phenol Saline Wastewater by Tao Zhang, Rongkai Guo, Fanshu Liu, Lei Zhang, Linxiao Li, Rongfei Zhang, Chaogang Shao, Junbo Zhou, Fan Ding, Lan Yu

“…In this study, we isolated a bioflocculant-producing <i>Bacillus paralicheniformis</i> BL-1 that is capable of phenol degradation in high-salinity conditions. Differential gene expression analysis revealed the down-regulation of genes related to the synthesis of extracellular polymeric substances and the up-regulation of poly-γ-glutamate biosynthesis in 10% NaCl conditions. …”
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Promising Therapeutic Functions of Bone Marrow Mesenchymal Stem Cells Derived-Exosome in Asthma by Jia-Ying Yuan, Xiang-Yun Wang, Zhi-Ying Tong, Yu-Chao Dong, Jia-Yi Zhao, Yi Zhang, Yan Shang

“…Points also hold that BMMSC-Exo could interfere with airway inflammation and airway remolding in asthma via modulating the immune response, regulating gene expression, adjusting the phenotype of macrophage, etc. …”
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Wharton’s Jelly Mesenchymal Stem Cell Conditioned Medium Ameliorates Diabetes-Induced Testicular Damage and Sperm Abnormalities by Mitigating Oxidative Stress, Apoptosis, and Infla... by Mojtaba Sargazi, Narges Karbalaei, Saied Karbalay-Doust, Sara Keshtgar, Zohre Aghaei

“…Real-time PCR detected Bax, Bcl-2, and tumor necrosis factor-alpha (TNF-α) gene expression. Our results showed that diabetes increased blood glucose levels, decreased insulin and sex hormone levels, induced testicular oxidative stress and apoptosis, and reduced sperm parameters compared to the control. …”
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A Full-Length Reference Floral Transcriptome of Boehmeria tricuspis Provides Insights into Apomeiosis and Polyploidy by Qing Tang, Ying Xu, Canhui Deng, Chaohua Cheng, Zhigang Dai, Zemao Yang, Chan Liu, Jianguang Su

“…Based on the generated database, gene expression of the female flowers of different ploidy levels and reproductive mode cytotypes was compared. …”
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CD226 Deficiency Alleviates Murine Allergic Rhinitis by Suppressing Group 2 Innate Lymphoid Cell Responses by Yang Xie, Yuan Zhang, Tianxiao Zhu, Jingchang Ma, Chujun Duan, Lu Yang, Tingting Wang, Ran Zhuang, Ka Bian, Lianjun Lu

“…ILC2s in the murine nasal mucosa expressed higher levels of CD226 after ovalbumin stimulation, and CD226 deficiency led to a reduction in the proportion of nasal ILC2s and ILC2-related inflammatory gene expression. Hence, the effect of CD226 on the AR mouse model may involve the regulation of ILC2 function rather than CD4+ T cells.…”
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