Circadian rhythm related genes signature in glioma for drug resistance prediction: a comprehensive analysis integrating transcriptomics and machine learning by Junbo Liao, Yingxing Duan, Xiangwang Xu, Yaxue Liu, Chaohong Zhan, Gelei Xiao

“…The studies of immune cell infiltration, genetic variations, differential gene expression pattern, and single cell analysis were performed for exploring the mechanisms of chemotherapy resistance in glioma. …”
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Long Noncoding RNA uc001pwg.1 Is Downregulated in Neointima in Arteriovenous Fistulas and Mediates the Function of Endothelial Cells Derived from Pluripotent Stem Cells by Lei Lv, Haozhe Qi, Xiangjiang Guo, Qihong Ni, Zezhen Yan, Lan Zhang

“…Recent studies indicate important roles for long noncoding RNAs (lncRNAs) as essential regulators of gene expression. However, the specific roles of lncRNAs in stenotic lesions of arteriovenous fistula (AVF) failure are still largely unknown. …”
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Multiomics-based assessment of the impact of airflow on diverse plant callus cultures by June-Sik Kim, Muneo Sato, Mikiko Kojima, Muchamad Imam Asrori, Yukiko Uehara-Yamaguchi, Yumiko Takebayashi, Thi Nhung Do, Thi Yen Do, Kieu Oanh Nguyen Thi, Hitoshi Sakakibara, Keiichi Mochida, Shinjiro Ogita, Masami Yokota Hirai

“…For each sample, gene expression was profiled with high-throughput RNA sequencing, 442 metabolites were measured using liquid chromatography (LC) with triple-quadrupole mass spectrometry (LC–QqQMS), and 31 phytohormones were quantified using ultra-performance LC coupled with a tandem quadrupole mass spectrometer equipped with an electrospray interface (UPLC-ESI-qMS/MS) and ultra-high-performance LC–orbitrap MS (UHPLC-Orbitrap MS). …”
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Can Melatonin Act as an Antioxidant in Hydrogen Peroxide-Induced Oxidative Stress Model in Human Peripheral Blood Mononuclear Cells? by Solaleh Emamgholipour, Arash Hossein-Nezhad, Mohammad Ansari

“…We aimed to investigate the possible effects of melatonin on gene expressions and activities of MnSOD and catalase under conditions of oxidative stress induced by hydrogen peroxide (H2O2) in peripheral blood mononuclear cells (PBMCs). …”
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Regulatory roles of eugenol in paraquat-altered SNCA/LZTS3/MAPT in the cerebellum of Wistar rats by Obinna Onwe Uchewa, Augustine Oseloka Ibegbu, Samuel Okoronkwo Okafor, Joseph Alo Nwafor, Ogugua Augustine Egwu

“…Motor impairments were determined using wire string and beam-walk; biomarkers were estimated using cerebellar homogenates, while frozen cerebellum was used to study LZTS3, MAPT, and SNCA gene expression. LZTS3 was significantly suppressed in the PQ-untreated group and highly expressed in the eugenol-treated group. …”
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Interaction mechanism of egg white- derived ACE inhibitory peptide TNGIIR with ACE and its effect on the expression of ACE and AT1 receptor by Zhipeng Yu, Hui Guo, David Shiuan, Chensi Xia, Wenzhu Zhao, Long Ding, Fuping Zheng, Jingbo Liu

“…Keywords: Egg white proteins, ACE inhibitory peptide, Gene expression, Antihypertensive effect, Molecular docking…”
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Molecular, Metabolic, and Physiological Responses to Progressive Biotic Stress Caused by Cucumber Mosaic Virus and Turnip Mosaic Virus in Saffron by Marzieh Shamshiri, Conchi Sánchez, Saleta Rico, Ali Mokhtassi-Bidgoli, Mahdi Ayyari, Hassan Rezadoost, Masoud Shams-Bakhsh

“…According to high-performance liquid chromatography (HPLC) analysis, CMV inoculation led to the highest reduction in crocin and safranal content, while inducing the highest increase in picrocrocin compared to the mock treatment. Gene expression analysis involved in the biosynthesis of crucial secondary metabolites showed a high correlation with the content of each metabolite. …”
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Identification of Differentially Expressed Genes in Pituitary Adenomas by Integrating Analysis of Microarray Data by Peng Zhao, Wei Hu, Hongyun Wang, Shengyuan Yu, Chuzhong Li, Jiwei Bai, Songbai Gui, Yazhuo Zhang

“…Pituitary adenomas, monoclonal in origin, are the most common intracranial neoplasms. Altered gene expression as well as somatic mutations is detected frequently in pituitary adenomas. …”
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EPIMR: Prediction of Enhancer-Promoter Interactions by Multi-Scale ResNet on Image Representation by Qiaozhen Meng, Yinuo Lyu, Xiaoqing Peng, Junhai Xu, Jijun Tang, Fei Guo

“…Prediction of enhancer-promoter interactions (EPIs) is key to regulating gene expression and diagnosing genetic diseases. Due to limited resolution, biological experiments perform not as well as expected while precisely identifying specific interactions, giving rise to computational biology approaches. …”
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Role of Rutin on Nitric Oxide Synthesis in Human Umbilical Vein Endothelial Cells by Azizah Ugusman, Zaiton Zakaria, Kien Hui Chua, Nor Anita Megat Mohd Nordin, Zaleha Abdullah Mahdy

“…Rutin promoted NO production in HUVEC by inducing eNOS gene expression (P<0.05), eNOS protein synthesis (P<0.01), and eNOS activity (P<0.05). …”
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Endocervical miRNA-142 expression in patients with pelvic inflammatory disease positive for Chlamydia trachomatis by Aliaa Zara Allah Hussein Al-Tememy, Maysaa S. Alshukri, Asmaa Kadhim Gatea

“…Highly conserved single-stranded noncoding RNAs called micro-RNAs (miRNAs), which control gene expression, have now been identified as significant effect in disease conditions. …”
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Exploring the Potential of <i>Candida</i> sp. SW4-6 as a Probiotic for Enhancing Water Quality in Aquaculture by Jie-Ying Li, Chun-Hung Liu

“…SW4-6 showed superior nitrite-N and ammonia-N reduction capabilities, with sucrose as the carbon source and complete reduction observed at a C/N ratio of 15–20. Gene expression analysis revealed the up-regulation of nitrite reductase in SW4-6 after inoculation, with significantly higher expression observed with sucrose as the carbon source. …”
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Conjugacy of two types of phenotypic variability of small-leaved linden by S. G. Baranov, I. E. Zykov, D. D. Kuznetsova

“…According to the authors, asynchronous growth, competition for light in conditions of high solar activity in 2014–2016 compared to the abnormal wet summer of 2017 led to an increase in FA due to destabilization of mechanisms of growth and regulation of gene expression, which contributed to a decrease in the stability of development. …”
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Different Transcriptional Profiles of Human Monocyte-Derived Dendritic Cells Infected with Distinct Strains of Mycobacterium tuberculosis and Mycobacterium bovis Bacillus Calmette-... by Nunzia Sanarico, Alessia Colone, Manuela Grassi, Viviana Speranza, Daniela Giovannini, Antonio Ciaramella, Vittorio Colizzi, Francesca Mariani

“…The analysis of the gene expression reveals that, despite a set of genes similarly modulated, DCs response resulted strain dependent. …”
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Regulation of UCP1 in the Browning of Epididymal Adipose Tissue by β3-Adrenergic Agonist: A Role for MicroRNAs by Zongji Zheng, Xiaomeng Liu, Qianwei Zhao, Lei Zhang, Chenzhong Li, Yaoming Xue

“…This suggests that potential UCP1-targeting miR-9 and miR-338-3p may be involved in the browning of epididymal adipose tissue by regulating UCP1 gene expression. In this study, we demonstrated that this increase of UCP1 is due, at least in part, to the decreased expression of certain UCP1-targeting miRNAs in epididymal adipose tissue compared to control.…”
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Involvement of the intracellular β-glucosidase BGL1B from Aspergillus niger in the regulation of lignocellulose-degrading enzymes’ synthesis by Zhen Zhang, Hua Li, Feiyu Dong, Hui Lin, Yanan Li, Kun Cheng, Hongge Chen

“…On the other hand, BGL1B’s transglycosylation products sophorose and laminaribiose were proved to be able to induce the expression of lignocellulose-degrading enzyme genes, which explained why OE::bgl1B showed the same enhanced enzyme activity and gene expression as Δbgl1B strain compared to the starting strain (WT). …”
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Modeling and designing enhancers by introducing and harnessing transcription factor binding units by Jiaqi Li, Pengcheng Zhang, Xi Xi, Liyang Liu, Lei Wei, Xiaowo Wang

“…Abstract Enhancers serve as pivotal regulators of gene expression throughout various biological processes by interacting with transcription factors (TFs). …”
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circ_0001588 Induces the Malignant Progression of Hepatocellular Carcinoma by Modulating miR-874/CDK4 Signaling by Xiaoyun Bin, Yichen Chen, Jiasheng Ma, Renchao Tang, Zhenrong Zhao, Kangxuan Wang, Jianchu Wang

“…Accumulating evidence indicates that circular RNAs (circRNAs) can interact with microRNAs to modulate gene expression in various cancers, including hepatocellular carcinoma (HCC). …”
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Immunoinfiltration Analysis of Mitochondrial Damage‐Related Genes in Lung Adenocarcinoma and Construction of a Classification and Prognostic Model Integrated With WGCNA and Machine... by Jirong Zhang, Lin Lin

“…ML models were constructed for classification and prognosis prediction, and validated in an independent Gene Expression Omnibus (GEO) dataset. Results The study revealed a significant relationship between mitochondrial damage and immune infiltration in LUAD. …”
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Diethyldithiocarbamate Delayed Wound-Induced Callus Formation in Potato Tubers by Inhibiting Superoxide Dismutase by CHENG Xinyan, SONG Bingfang, LIU Ning, TIAN Wenmao, YIN Yan, LI Yongcai, BI Yang, WANG Yi

“…We determined the StSODs gene expression and activity of SOD, reactive oxygen species (ROS) content, phenylpropanoid metabolism-related enzyme activity, total phenols and lignin contents at the wound site during the healing process. …”
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