Truncated SPAG9 as a novel candidate gene for a new syndrome: Coarse facial features, albinism, cataract and developmental delay (CACD syndrome) by Majid Alfadhel, Bashayr S. Alhubayshi, Muhammad Umair, Ahmed Alfaidi, Deemah Alwadaani, Essra Aloyouni, Safdar Abbas, Abdulkareem Al Abdulrahman, Mohammed Aldrees, Abeer Al Tuwaijri, Ruaa S. Alharithy, Abdulaziz Alajlan, Abdulrahman Alswaid, Saad Almohrij, Sultan Al-Khenaizan

“…Furthermore, RT-qPCR revealed a substantial reduction of SPAG9 gene expression at the mRNA level in the affected individuals of both families, thus supporting the pathogenic nature of the identified variant. …”
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Effects of microplastics on microbial community and greenhouse gas emission in soil: A critical review by Guanlin Chen, Saisai Guo, Linan Liu, Wenzhu Zhang, Jingchun Tang

“…Firstly, this review details that MPs alter microbial abundance, structure, activity and gene expression, directly stimulating CO2 and N2O emissions, though their impact on CH4 remains inconclusive. …”
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The Underlying Mechanism Involved in Gefitinib Resistance and Corresponding Experiment Validation in Lung Cancer by Puwei Song, Jianghui Zhou, Kaiqin Wu, Wenli Wang, Shaorui Gu

“…Open-accessed data of lung cancer patients were downloaded from The Cancer Genome Atlas Program and Gene Expression Omnibus databases. CCK8, colony formation, and 5-ethynyl-2′-deoxyuridine assays were utilized to evaluate the cell proliferation ability. …”
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In vivo Study of the Histone Chaperone Activity of Nucleolin by FRAP by Xavier Gaume, Karine Monier, Françoise Argoul, Fabien Mongelard, Philippe Bouvet

“…Nucleolin possesses, in vitro, chromatin co-remodeler and histone chaperone activities which could explain numerous functions of nucleolin related to the regulation of gene expression. The goal of this report was to investigate the consequences of nucleolin depletion on the dynamics of histones in live cells. …”
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Effects of Ubiquinol-10 on MicroRNA-146a Expression In Vitro and In Vivo by Constance Schmelzer, Mitsuaki Kitano, Gerald Rimbach, Petra Niklowitz, Thomas Menke, Kazunori Hosoe, Frank Döring

“…MicroRNAs (miRs) are involved in key biological processes via suppression of gene expression at posttranscriptional levels. According to their superior functions, subtle modulation of miR expression by certain compounds or nutrients is desirable under particular conditions. …”
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Unveiling Tissue‐Specific RNA Landscapes in Mouse Organs During Fasting and Feeding Using Nanopore Direct RNA Sequencing by Chengfei Jiang, Ping Li, Haiming Cao

“…However, current knowledge remains limited, as short‐read RNA sequencing—the predominant method for assessing gene expression—depends on incomplete gene annotations and struggles to resolve the diverse transcripts produced by genes. …”
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The Effect of Tianmai Xiaoke Pian on Insulin Resistance through PI3-K/AKT Signal Pathway by Nana Wang, Tiegang Li, Ping Han

“…Furthermore, we also observed that TMXKP could significantly decrease IRS-1, IRS-2, PI3-K p85α, and AKT2 gene expression and also IRS-1, IRS-2, PI3-K, AKT2, and p-AKT2 protein expression levels P<0.05 in diabetic rats. …”
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Neutrophil Extracellular Traps Contribute to the Disease Severity of Dengue Virus Infection by Cucunawangsih Cucunawangsih, Ratna Sari Wijaya, Nata Pratama Hardjo Lugito, Ivet Suriapranata

“…Results: Based on the transcriptomic analysis, the whole blood gene expression functional in neutrophil activities and NETs formation was upregulated with dengue disease severity. …”
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Characteristics and clinical significance of immune cells in omental milky spots of patients with gastric cancer by Yasunobu Mano, Yasunobu Mano, Yuka Igarashi, Yuka Igarashi, Keisuke Komori, Keisuke Komori, Itaru Hashimoto, Itaru Hashimoto, Hayato Watanabe, Kosuke Takahashi, Kazuki Kano, Hirohito Fujikawa, Takanobu Yamada, Hidetomo Himuro, Hidetomo Himuro, Taku Kouro, Taku Kouro, Feifei Wei, Feifei Wei, Kayoko Tsuji, Kayoko Tsuji, Shun Horaguchi, Shun Horaguchi, Shun Horaguchi, Mitsuru Komahashi, Mitsuru Komahashi, Mitsuru Komahashi, Takashi Oshima, Tetsuro Sasada, Tetsuro Sasada

“…In this study, we investigated gene expression profiles in cells from omental milky spots of patients with gastric cancer (n = 37) by RNA sequencing analysis and classified the patients into four groups (G1-4). …”
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The context signals of mitochondrial miRNAs (mitomiRs) of mammals by O. V. Vishnevsky, P. S. Vorozheykin, I. I. Titov

“…MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at the post-transcriptional level in the cytoplasm and play an important role in a wide range of biological processes. …”
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The Impact of the Coexpression of MET and ESR Genes on Prognosticators and Clinical Outcomes of Breast Cancer: An Analysis for the METABRIC Dataset by Nehad M. Ayoub, Ghaith M. Al-Taani, Amer E. Alkhalifa, Dalia R. Ibrahim, Aymen Shatnawi

“…The METABRIC dataset for breast cancer was obtained from the cBioPortal public domain. Gene expression data for MET, ESR1, and ESR2, as well as the putative copy number alterations (CNAs) for MET were retrieved. …”
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Integrated Bioinformatic Analysis Identifies Networks and Promising Biomarkers for Hepatitis B Virus-Related Hepatocellular Carcinoma by Yun Ji, Yue Yin, Weizhen Zhang

“…Here, three microarray datasets, totally containing 170 tumoral samples and 181 adjacent normal tissues from the liver of patients suffering from HBV-related HCC assembled from the Gene Expression Omnibus (GEO) database, were subjected to integrated analysis of differentially expressed genes (DEGs). …”
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Methods of massive parallel reporter assays for investigation of enhancers by S. E. Romanov, D. A. Kalashnikova, P. P. Laktionov

“…The methods described allow assessing the functional role of the nucleotide sequence of a regulatory element, to determine its exact boundaries and to assess the influence of the local state of chromatin on the activity of enhancers and gene expression. These approaches have contributed substantially to the understanding of the fundamental principles of gene regulation.…”
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Deciphering the dose-dependent effects of thymoquinone on cellular proliferation and transcriptomic changes in A172 glioblastoma cells. by Rachana Pandey, Purushothaman Natarajan, Umesh K Reddy, Wei Du, Cristian Sirbu, Moussa Sissoko, Gerald R Hankins

“…RNA-seq revealed no significant gene expression changes at 2.5 μM and 5 μM TQ concentrations. …”
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Glymphatic dysfunction and neurodegeneration in ALS: Longitudinal insights from rNLS8 TDP-43 mice by Akram Zamani, Adam K. Walker, David K. Wright

“…Motor function, advanced MRI biomarkers of neurodegeneration, and cortical glymphatic pathway gene expression were assessed together with dynamic contrast-enhanced MRI (DCE-MRI) assessment of glymphatic function at 0-, 3-, 7-, and 21-days after removing mice from Dox feed to initiate cytoplasmic human TDP-43 expression. …”
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The potential of polyphenol compounds in grapes to reduce oxidative stress and inflammation after exercise: systematic review by Novadri Ayubi, Atika Syafawi, Anton Komaini, Dhea Regita Sastika Putri, Ilham Ilham, Deby Tri Mario, Dyah Fitria Padmasari, Junian Cahyanto Wibawa, Procopio B. Dafun Jr.

“…In vivo studies also confirmed these anti-inflammatory and antioxidant benefits by stimulating eNOS gene expression and increasing CAT, SOD, and GPx4 levels. …”
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Plant Antimicrobial Peptides and Their Main Families and Roles: A Review of the Literature by Samuel Salomão Silva de Oliveira, Milena Bellei Cherene, Gabriel Bonan Taveira, Érica de Oliveira Mello, André de Oliveira Carvalho, Valdirene Moreira Gomes

“…We also discuss the current knowledge of their biological activities, gene expression, and possible uses as antimicrobial molecules and in plant biotechnology.…”
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Synergistic impacts of propargite exposure and deformed wing virus infection on the health of western honey bees by Chia-Yang Lin, Yu-Chun Lin, Yun-Heng Lu, Shiang-Jiuun Chen, Yu-Hsien Lin, Yao-Kuang Tseng, Yu-Tzu Lin, Yueh-Lung Wu, Rong-Nan Huang

“…However, simultaneous treatment of DWV and acaricide increased both the immune response and detoxification gene expression, thereby indicating enhanced bee resistance. …”
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Changes in RNA Splicing: A New Paradigm of Transcriptional Responses to Probiotic Action in the Mammalian Brain by Xiaojie Yue, Lei Zhu, Zhigang Zhang

“…Most studies have primarily investigated how gut bacteria modulate host epigenetics and gene expression; their impact on host alternative splicing, particularly in the brain, remains largely unexplored. …”
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Immunohistochemical evaluation of P53 in squamous cell carcinoma of the esophagus by Kala K, Sarumathy G, Nithya I, Prathiba A

“…Materials and methods: This is a retrospective study of squamous cell carcinoma of the oesophagus and in this study, for 55 cases of ESCC p53 gene expression was analyzed by Immunohistochemistry and these findings were then compared with clinicopathological parameters. …”
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