The relationship of lamins with epigenetic factors during aging by R. N. Mustafin, E. K. Khusnutdinova

“…We suggest that lamins can be attributed to epigenetic factors, since they are part of the NURD, interact with histone deacetylases and regulate gene expression without changing the nucleotide sequences. …”
Get full text

Identification of proteins that can participate in the recruitment of Ttk69 to genomic sites of Drosophila melanogaster by I. S. Osadchiy, T. N. Fedorova, P. G. Georgiev, O. G. Maksimenko

“…However, it is still unknown what provides for specific recruitment of Ttk to chromatin in the process of negative/positive regulation of a target gene expression. Although Ttk69 has DNA-binding activity, no extended specific motif has been identified. …”
Get full text

Identifying unstable CNG repeat loci in the human genome: a heuristic approach and implications for neurological disorders by Varun Suroliya, Bharathram Uppili, Manish Kumar, Vineet Jha, Achal K. Srivastava, Mohammed Faruq

“…The genes with these highly variable repeats also exhibited higher gene expression levels in the brain according to the tissue expression dataset (GTEx). …”
Get full text

Classification of Thyroid Nodules with Stacked Denoising Sparse Autoencoder by Zexin Li, Kaiji Yang, Lili Zhang, Chiju Wei, Peixuan Yang, Wencan Xu

“…This study aims to develop a classifier for conveniently clinical utility. Methods. Gene expression data of thyroid nodule tissues were collected from three public databases. …”
Get full text

YgaE Regulates Out Membrane Proteins in Salmonella enterica Serovar Typhi under Hyperosmotic Stress by Min Wang, Ping Feng, Xun Chen, Haifang Zhang, Bin Ni, Xiaofang Xie, Hong Du

“…In this study, we constructed ΔygaE mutant and a microarray was performed to investigate the role of ygaE in regulation of gene expression changes in response to hyperosmotic stress in S. …”
Get full text

Identification of Key Genes and Pathways Associated with Age-Related Macular Degeneration by Junyu Zhang, Yu Zhou

“…To better understand the molecular and pathway changes in human AMD RPE/choroid tissues, we searched the literature and found three independent studies using high-throughput technology to analyze gene expression in 54 human AMD RPE/choroid tissues and 46 age-matched healthy controls. …”
Get full text

Transcriptomic analysis of the defense response in “Cabernet Sauvignon” grape leaf induced by Apolygus lucorum feeding by Heng Yao, Suhong Gao, Tianhua Sun, Guona Zhou, Changkuan Lu, Baojia Gao, Wenshu Chen, Yiming Liang

“…The consistency between the gene expression and transcriptome sequencing results further supports these findings. …”
Get full text

Human Urine-Derived Stem Cells: Potential for Cell-Based Therapy of Cartilage Defects by Long Chen, Lang Li, Fei Xing, Jing Peng, Kun Peng, Yuanzheng Wang, Zhou Xiang

“…In this study, we revealed that induced hUSCs expressed chondrogenic-related proteins, including aggrecan and collagen II, and their gene expression levels were upregulated in vitro. Moreover, we combined hUSCs with hyaluronic acid (HA) and injected hUSCs-HA into a rabbit knee joint with cartilage defect. …”
Get full text

hsa_circRNA_000166 Facilitated Cell Growth and Limited Apoptosis through Targeting miR-326/LASP1 Axis in Colorectal Cancer by Qin Hao, Zhongtao Zhang

“…Here, we firstly downloaded and analyzed the circRNA expression profile of CRC from the Gene Expression Omnibus (GEO) database. And we identified 181 differentially expressed circRNAs between 10 pairs of CRC and adjacent normal tissues. …”
Get full text

Daily reference evapotranspiration prediction using empirical and data-driven approaches: A case study of Adana plain by Semin Topaloğlu Paksoy, Deniz Levent Koç

“…The objective of this research was to examine the effectiveness of five different data-driven techniques, including artificial neural networks "multilayer perceptron" (ANN), gene expression programming (GEP), random forest (RF), support vector machine "radial basis function" (SVM), and multiple linear regression (MLR) to model the daily ET0. …”
Get full text

RETRACTED: Palmitic Acid Impedes Extravillous Trophoblast Activity by Increasing MRP1 Expression and Function by Yunali Ashar, Qiuxu Teng, John N. D. Wurpel, Zhe-Sheng Chen, Sandra E. Reznik

“…Palmitic acid increased <i>ABCC1</i> gene expression and MRP1 protein expression in both cell lines. …”
Get full text

The <i>OsGATA</i> gene family as a promising candidate for applying the CRISPR/Cas genome editing technology to improve the nutritional and yield qualities of rice (<i>Oryza sativa... by E. A. Nesterova, N. A. Shvachko

“…Plants, as sedentary organisms, require more efficient regulation of gene expression. GATA factors are transcription factors (TFs) that affect the production of phytohormones and mediate the stress response. …”
Get full text

To describe the subsets of malignant epithelial cells in gastric cancer, their developmental trajectories and drug resistance characteristics by Tingting Xu, Tianying Zhang, Yan Sun, Sijia Wu

“…Among 27 epithelial subgroups, five malignant subpopulations were identified, each defined by unique marker gene expressions and playing diverse roles in tumor progression. …”
Get full text

The Multifaceted Role of Extracellular Vesicles in Glioblastoma: microRNA Nanocarriers for Disease Progression and Gene Therapy by Natalia Simionescu, Radu Zonda, Anca Roxana Petrovici, Adriana Georgescu

“…MicroRNAs (miRNAs) are small, non-coding RNAs that regulate gene expression post-transcriptionally through specific pairing with target messenger RNAs (mRNAs). …”
Get full text

Identification of the immune infiltration and biomarkers in ulcerative colitis based on liquid–liquid phase separation-related genes by Zhixing Hong, Shilin Fang, Haihang Nie, Jingkai Zhou, Yuntian Hong, Lan Liu, Qiu Zhao

“…External cohort and UC cell model validation indicated the similar immune infiltration levels, gene expression and cytokine expression patterns. We determined the seven high accuracy diagnostic genes of UC patients and provide a new perspective on immunoregulation in UC pathogenesis. …”
Get full text

The role of microRNAs in learning and long-term memory by L. N. Grinkevich

“…It describes microRNA biogenesis and the role of miRNAs in the regulation of gene expression, as well as the latest achievements in studying the functional role of microRNAs in learning and in long-term memory formation, depending on the activation or inhibition of their expression. …”
Get full text

Intrathyroidal Clear Cell Tumor of Parathyroid Origin with Review of Literature by Daniela Pirela, Daniela Treitl, Siba El Hussein, Robert Poppiti, Thomas Mesko, Alex Manzano

“…Fine needle aspiration biopsy of the nodule revealed thyroid follicular cells without atypia and subsequent Afirma® Gene Expression Classifier (GEC) testing results were suspicious for malignancy. …”
Get full text

Studyof resistance of pathogenic and opportunistic fungi toantimycotics by A. D. Kozlova, S. P. Yatsentyuk, V. V. Sokolov, M. G. Manoyan

“…The results obtained can serve as a basis for the use of molecular methods to characterize fungi of Candida and Trichophyton genera, however, taking into account the biological features of pathogens from different groups it is reasonable to use several significant genome regions or the results of the whole genome sequencing, as well as the gene expression analysis for successful forecasting of potential resistance.…”
Get full text

Establishment and Validation of a Gene Signature-Based Prognostic Model to Improve Survival Prediction in Adrenocortical Carcinoma Patients by Xiaoqin Ge, Zhenzhen Liu, Xuehua Jiao, Xueyan Yin, Xiujie Wang, Gengxu Li

“…Using a series of bioinformatic and statistical approaches, a gene-expression signature was established and validated in two independent cohorts. …”
Get full text

Aryl Hydrocarbon Receptor Deficiency in an Exon 3 Deletion Mouse Model Promotes Hematopoietic Stem Cell Proliferation and Impacts Endosteal Niche Cells by Zeenath Unnisa, Kameshwar P. Singh, Ellen C. Henry, Catherine L. Donegan, John A. Bennett, Thomas A. Gasiewicz

“…There was a significant increase in mesenchymal stem cells constituting the endosteal BM niche. Gene expression analyses of HSCs revealed an increase in expression of genes involved in proliferation and maintenance of quiescence. …”
Get full text