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101
Alternative RNA Splicing in Cardiac Diseases
Published 2025-01-01“…Alternative splicing (AS), a critical process for gene expression regulation, allows a single precursor RNA to produce multiple transcript variants. …”
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102
Anopheles gambiae phagocytic hemocytes promote Plasmodium falciparum infection by regulating midgut epithelial integrity
Published 2025-02-01“…The mosquito’s hemocytes also control the midgut microbiota and immune gene expression. Our study unveils novel hemocyte functions that are exploited by the human malaria parasite to evade the mosquito’s immune system.…”
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103
François Gros : Une personnalité de premier plan, un homme secret
Published 2024-01-01“…I joined François Gros’ laboratory in 1975, to study mechanisms of gene expression in eukaryotes. Despite the lack of powerful tools, that would be brought later by genetic engineering, I obtained publishable results and was allowed to defend a third cycle thesis. …”
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104
Toxicity of Low-dose Graphene Oxide Nanoparticles in an in-vivo Wild Type of Caenorhabditis elegans Model
Published 2020-12-01“…In the examination of the longevity of nematodes, it was found that the lifespan of all GO NP-exposed worms was significantly shortened as compared to the untreated worms. Gene expression of sod-1, sod-3, and ctl-2 presented significantly higher induction folds in the exposed worms compared with the controls. …”
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105
Advances in personalized gastroenterology and hepatology 2016
Published 2016-08-01“…On the other hand, using high throughput array and other technologies, it is possible to simultaneously analyze thousands of genes (DNA) or gene products (RNA and proteins), resulting in an individual gene or gene expression profile (‘signature’) or to characterize the individual microbiome and its pathogenetic potential. …”
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106
INTESTINAL MICROBIOME - A LEADING FACTOR IN HUMAN HEALTH AND DISEASES
Published 2018-08-01“…On the other hand, high throughput array and other technologies made it possible to simultaneously analyze thousands of genes (DNA) or gene products (RNA and proteins), resulting in an individual gene or gene expression profile (‘signature’) or to characterize the individual microbiome and its pathogenetic potential. …”
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107
Atlas of multilineage stem cell differentiation reveals TMEM88 as a developmental regulator of blood pressure
Published 2025-02-01“…Interrogation of temporal and signalling-specific gene expression in this atlas, evaluated against cell type-specific gene expression in human complex trait data highlights the WNT-inhibitor gene TMEM88 as a regulator of mesendodermal lineages influencing cardiovascular and anthropometric traits. …”
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108
Identification and functional analysis of hub genes involved in deoxynivalenol-induced enterotoxicity in porcine (Sus scrofa)
Published 2025-01-01“…In summary, exposure to DON is more likely to result in increased rather than decreased gene expression. Six of the upregulated genes, which are involved in immunoregulation and inflammation, were identified as hub genes related to DON-induced enterotoxicity in pigs. …”
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109
Analysis of glutamate-dependent mechanism and optimization of fermentation conditions for poly-gamma-glutamic acid production by Bacillus subtilis SCP017-03.
Published 2025-01-01“…The introduction of glutamate substantially altered gene expression within the central metabolic pathway of cellular carbon. …”
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110
Dietary tea tree (Melaleucae Aetheroleum) oil fortifies growth, biochemical, immune-antioxidant trait, gene function, tissue reaction, and Aeromonas sobria resistance in Nile tilap...
Published 2025-01-01“…The impact on growth performance, biochemical indices, immune function, oxidant/antioxidant activity, gene expression, histopathology, and resistance against Aeromonas sobria in Nile tilapia (Oreochromis niloticus) was investigated. …”
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111
The Multifaceted Roles of Myrrha in the Treatment of Breast Cancer: Potential Therapeutic Targets and Promises
Published 2024-12-01“…Method: The identified targets’ expression profiles were determined at the mRNA and protein levels using The Breast Cancer Gene-Expression Miner v5.0 (bcGen-ExMiner v5.0) and The Human Protein Atlas datasets, respectively. …”
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112
Placental malaria infection is associated with downregulation of STAT-6 and ANG-1 in decidual macrophages
Published 2025-02-01“…Notably, the gene expression levels of the transcription factor STAT-6 and angiogenic factor ANG-1 were significantly lower in infected placentas. …”
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113
Comparisons of performances of structural variants detection algorithms in solitary or combination strategy.
Published 2025-01-01“…Structural variants (SVs) have been associated with changes in gene expression, which may contribute to alterations in phenotypes and disease development. …”
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114
Non-coding RNAs and exosomal ncRNAs in colorectal cancer
Published 2025-02-01“…In recent years, increasing attention has been paid to the role of non-coding RNA (ncRNA) and exogenous ncRNA in the development and progression of CRC. ncRNAs play an essential role in the regulation of gene expression and cell function, and dysregulation of ncRNA expression is associated with the onset and progression of CRC. …”
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115
Assessment of SREBP Activation Using a Microsomal Vesicle Budding Assay
Published 2024-12-01“…To be active, SREBPs are translocated to the Golgi where the transcriptionally active N-terminus is cleaved and released to the nucleus to regulate gene expression. Nuclear SREBP levels can be determined by immunoblot analysis; however, this method can only determine the steady-state levels of nuclear SREBPs and does not capture the actual status of activation. …”
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116
Simulated gastrointestinal digestion of milk caseins containing A1 β-casein does not lead to increased production of inflammatory proteins in intestinal epithelial cells in vitro w...
Published 2025-02-01“…No difference was found in the effects of the digestion products of each β-casein on gene expression of inflammatory markers interleukin (IL)-8, carcinoembryonic antigen-related cell adhesion molecule (CEACAM)6 or intestinal alkaline phosphatase (IAP). …”
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117
Identification of hub genes and pathogenesis in Kawasaki disease based on bioinformatics analysis
Published 2024-04-01“…Materials and Methods: Gene Expression Omnibus (GEO) datasets GSE68004 and GSE73461 were downloaded, and the differentially expressed genes (DGEs) were taken, along with DEGs enrichment analysis and protein interaction network. …”
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118
Harnessing amino acid pathways to influence myeloid cell function in tumor immunity
Published 2025-02-01“…Abstract Amino acids are pivotal regulators of immune cell metabolism, signaling pathways, and gene expression. In myeloid cells, these processes underlie their functional plasticity, enabling shifts between pro-inflammatory, anti-inflammatory, pro-tumor, and anti-tumor activities. …”
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119
Induction of systemic resistance through calcium signaling in Arabidopsis exposed to air plasma-generated dinitrogen pentoxide.
Published 2025-01-01“…In addition, jasmonic acid (JA)-related gene expression was induced within 10 minutes, and a significant upregulation of the defense-related gene PDF1.2 was observed after 1 day of exposure to N2O5 gas. …”
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120
Disorders in brassinosteroids signal transduction triggers the profound molecular alterations in the crown tissue of barley under drought.
Published 2025-01-01“…On the other hand, a set of genes expressed independently of the genotype was identified, including dehydrin encoding genes. …”
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