<i>METTL3</i> and <i>FTO</i> Regulate Heat Stress Response in Hu Sheep Through Lipid Metabolism via m6A Modification by Bowen Chen, Chao Yuan, Tingting Guo, Jianbin Liu, Zengkui Lu

“…In the lipid deposition heat stress model of preadipocytes, the regulation of gene expression was similar to that in hepatocytes.…”
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Epigenetics and Shared Molecular Processes in the Regeneration of Complex Structures by Labib Rouhana, Junichi Tasaki

“…Perhaps the most fundamental of such molecular processes entails chromatin rearrangements, which prime large changes in gene expression required for differentiation and/or dedifferentiation of progenitor cells. …”
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Early Osteogenic Differentiation Stimulation of Dental Pulp Stem Cells by Calcitriol and Curcumin by Mohammad Samiei, Atefeh Abedi, Simin Sharifi, Solmaz Maleki Dizaj

“…Early osteogenic differentiation was evaluated and confirmed by the gene expression level of ALP and its activity. Curcumin individually and in combination with calcitriol increased ALP activity and osteoblast-specific mRNA expression of ALP when DPSCs were cultured in an osteogenic medium. …”
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LANCL1 as the Key Immune Marker in Neuropathic Pain by Yu Shi, XueFei Zhang, Qian Fang, Hongrui Zhan, Xianglong Wang, Xiyan Huang, Tao Fan, Wei Liu, Wen Wu

“…The data sets of GSE145199 and GSE145226 in Gene Expression Omnibus (GEO) database was used to analyze, and the key immune markers were verified by GSE70006 and GSE91396, and the infiltration degree of immune cells in different samples were analyzed by CIBERSORT analysis package. …”
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Hepatocyte Turnover in Chronic HCV-Induced Liver Injury and Cirrhosis by Nikolaos P. Karidis, Ioanna Delladetsima, Stamatios Theocharis

“…New insights in HCV-induced hepatocellular injury, differential gene expression, and regenerative pathways have recently revealed a different pattern of progression to irreversible parenchymal liver damage. …”
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3C-BASED METHODS FOR 3D GENOME ORGANIZATION ANALYSIS by N. R. Battulin, V. S. Fishman, Yu. L. Orlov, A. G. Menzorov, D. A. Afonnikov, O. L. Serov

“…The 3D organization of an eukaryotic genome plays an important role in nuclear gene expression. Until recently, studies of this organization were limited by light microscopy and electron microscopy methods. …”
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Evaluation of Fluorescent Analogs of Deoxycytidine for Monitoring DNA Transitions from Duplex to Functional Structures by Yogini P. Bhavsar, Samantha M. Reilly, Randy M. Wadkins

“…Topological variants of single-strand DNA (ssDNA) structures, referred to as “functional DNA,” have been detected in regulatory regions of many genes and are thought to affect gene expression. Two fluorescent analogs of deoxycytidine, Pyrrolo-dC (PdC) and 1,3-diaza-2-oxophenoxazine (tC∘), can be incorporated into DNA. …”
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Epigenetic Modifications and Potential New Treatment Targets in Diabetic Retinopathy by Lorena Perrone, Carmela Matrone, Lalit P. Singh

“…Indeed, epigenetic changes may lead to stable modification of gene expression, participating in DR pathogenesis. Moreover, increasing evidences suggest that environmental factors such as chronic hyperglycemia are implicated DR progression and may also affect the epigenetic state. …”
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Microgravity, Stem Cells, and Cancer: A New Hope for Cancer Treatment by Uğur Topal, Cihan Zamur

“…Microgravity has been shown to have significant effects on cellular proliferation, invasion, apoptosis, migration, and gene expression, specifically in tumor cells, and these effects may also exist in stem and cancer stem cells. …”
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Comparisons of performances of structural variants detection algorithms in solitary or combination strategy. by De-Min Duan, Chinyi Cheng, Yu-Shu Huang, An-Ko Chung, Pin-Xuan Chen, Yu-An Chen, Jacob Shujui Hsu, Pei-Lung Chen

“…Structural variants (SVs) have been associated with changes in gene expression, which may contribute to alterations in phenotypes and disease development. …”
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The Role of p38 MAPK in the Aetiopathogenesis of Psoriasis and Psoriatic Arthritis by Athanasios Mavropoulos, Eirini I. Rigopoulou, Christos Liaskos, Dimitrios P. Bogdanos, Lazaros I. Sakkas

“…Signaling pathway defects have long been hypothesized to participate in the pathology of psoriasis, yet their implication in the altered psoriatic gene expression still remains unclear. Emerging data suggest a potential pathogenic role for mitogen activated protein kinases p38 (p38 MAPK) extracellular signal-regulated kinase 1/2 (ERK1/2), and c-Jun N-terminal kinase (JNK) in the development of psoriasis. …”
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The Potential Importance of MicroRNAs as Novel Indicators How to Manage Patients with Juvenile Idiopathic Arthritis More Effectively by Krzysztof Orczyk, Elzbieta Smolewska

“…Small, noncoding sequences of ribonucleic acid called microRNAs (miRNAs, miR) are functioning as posttranscriptional regulators of gene expression. As they draw increasing attention of rheumatologists, there is a growing body of evidence concerning specific molecules that may affect the long-term care of patients with inflammatory arthritides. …”
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Nobiletin Protects Endothelial Cell Function via Upregulation of eNOS/ET-1 and Antioxidant Status-Related Genes under Nonstimulated and Inflammatory Conditions by Lu Li, Biyun Zhang, Ludovica De Pieri, Yue Wu, Karen Birch, Christine Boesch

“…Our aim was to investigate the potential of nobiletin to enhance endothelial cell functionality under nonstimulated and inflammatory conditions. To this end, gene expression relevant to nitric oxide (NO) production, endothelin 1 (ET-1), and antioxidant status in human endothelial cells EA.hy926 was determined using real-time PCR. …”
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Intratumor heterogeneity in KRAS signaling shapes treatment resistance by Oleksi Petrenko, Varvara Kirillov, Stephen D'Amico, Nancy C. Reich

“…We identify distinct cell populations that vary in their gene expression patterns pertaining to the predicted level of KRAS signaling activity, cell growth, and differentiation commitment within each tumor. …”
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Dynamic assignment and maintenance of positional identity in the ventral neural tube by the morphogen sonic hedgehog. by Eric Dessaud, Vanessa Ribes, Nikolaos Balaskas, Lin Lin Yang, Alessandra Pierani, Anna Kicheva, Bennett G Novitch, James Briscoe, Noriaki Sasai

“…Assays of intracellular signal transduction and gene expression indicate that the duration as well as level of signalling is critical for morphogen interpretation. …”
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Identification of Bexarotene as a PPARγ Antagonist with HDX by David P. Marciano, Dana S. Kuruvilla, Bruce D. Pascal, Patrick R. Griffin

“…The RXRs form heterodimers with several nuclear receptors (NRs), including peroxisome proliferator-activated receptor gamma (PPARγ), to regulate target gene expression through cooperative recruitment of transcriptional machinery. …”
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MicroRNAs in Neurotoxicity by Prameet Kaur, Arunmozhiarasi Armugam, Kandiah Jeyaseelan

“…MicroRNAs are gaining importance as regulators of gene expression with the capability to fine-tune and modulate cellular events. …”
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Modulation of the Wound Healing through Noncoding RNA Interplay and GSK-3β/NF-κB Signaling Interaction by Xianyi Wang, Wanqiu Li, Shengdi Lu, Zhongliang Ma

“…Noncoding RNAs, a large class of molecules that regulate gene expression at the posttranscriptional or posttranslational level, play an important role in various stages of wound healing, especially in the stage of inflammation. …”
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The Role of Noncoding RNA in Airway Allergic Diseases through Regulation of T Cell Subsets by Shenghao Cheng, Qingping Tang, Shaobing Xie, Sihui Wen, Hua Zhang, Zhihai Xie, Weihong Jiang

“…The human body is frequently exposed to allergens and environmental irritants that trigger immune and inflammatory responses, resulting in altered gene expression. Mounting evidence suggested that epigenetic alterations were strongly associated with the progression and severity of allergic diseases. …”
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Tomato mitogen-activated protein kinase: mechanisms of adaptation in response to biotic and abiotic stresses by Yumei Shi, Zhifang Zhang, Zhenghao Yan, Honglong Chu, Changxin Luo

“…MAPK cascades respond to various environmental stress factors by modulating associated gene expression, influencing plant hormone synthesis, and facilitating interactions with other environmental stressors. …”
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