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961
Rcor2 Is Required for Somatic Differentiation and Represses Germline Cell Fate
Published 2022-01-01“…In contrast, Rcor2 knockout promotes primordial germ cells (PGCs) specific gene expression and possibly PGC formation. Mechanistically, we revealed that Rcor2 inhibits expression of genes required for PGC development, such as Dppa3 and Dazl, by associating to their promoters and enhancing local suppressive H3K9me3 modifications. …”
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962
CLOCK Genes and Circadian Rhythmicity in Alzheimer Disease
Published 2011-01-01“…At the same time, the impact of neuropsychiatric medication on CLOCK gene expression is under investigation.…”
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963
Long Noncoding RNAs-Related Diseases, Cancers, and Drugs
Published 2013-01-01“…Long noncoding RNA (lncRNA) function is described in terms of related gene expressions, diseases, and cancers as well as their polymorphisms. …”
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964
Anti- and Protumorigenic Effects of PPARγ in Lung Cancer Progression: A Double-Edged Sword
Published 2012-01-01“…Peroxisome proliferator-activated receptor-γ (PPARγ) is a member of the nuclear receptor superfamily of ligand-activated transcription factors that plays an important role in the control of gene expression linked to a variety of physiological processes, including cancer. …”
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965
Synonymous Codon Usage Controls Various Molecular Aspects
Published 2017-12-01“…One of the most prominent observations on the non-neutrality of synonymous codons is the correlation between SCUB and levels of gene expression, such that highly expressed genes tend to have a higher preference toward so-called optimal codons than lowly expressed genes. …”
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966
Advances in Research Related to MicroRNA for Diabetic Retinopathy
Published 2024-01-01“…MicroRNAs (miRNAs) are vital regulators of gene expression and participate in cell growth, differentiation, development, and apoptosis. …”
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967
Methylation-Demethylation Dynamics: Implications of Changes in Acute Kidney Injury
Published 2018-01-01“…An interplay of the methylation-demethylation machinery controls the process of gene expression. Since acute kidney injury (AKI), a major risk factor for chronic kidney disease and death, is characterised by aberrant expression of genes, understanding the dynamics of methylation and demethylation will provide new insights into the intricacies of the disease. …”
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968
Lutein Suppresses the Maturation and Function of Bone Marrow-Derived Dendritic Cells
Published 2024-04-01“…Lutein also decreased IL-12p40 and IL-6 gene expression and secretion in LPS-stimulated DCs. Furthermore, lutein significantly enhanced the endocytic ability of LPS-stimulated DCs. …”
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969
Random k conditional nearest neighbor for high-dimensional data
Published 2025-01-01“…Moreover, the experiments on gene expression datasets show that the proposed method is promising in terms of predictive classification performance.…”
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970
Dietary tea tree (Melaleucae Aetheroleum) oil fortifies growth, biochemical, immune-antioxidant trait, gene function, tissue reaction, and Aeromonas sobria resistance in Nile tilap...
Published 2025-01-01“…The impact on growth performance, biochemical indices, immune function, oxidant/antioxidant activity, gene expression, histopathology, and resistance against Aeromonas sobria in Nile tilapia (Oreochromis niloticus) was investigated. …”
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971
Analysis of the Effect of Human Type I Collagen-Derived Peptide on Bone Regenerative Capacity and Comparison with Various Collagen Materials In Vivo
Published 2025-01-01“…The in vitro assays revealed that Cellnest promoted cell proliferation, adhesion, and migration. Gene expression analysis demonstrated that Cellnest significantly increased the levels of the bone formation markers ALP and COL1. …”
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972
High-fat diet-induced liver injury in Channa argus through lipid metabolism, anti-oxidative status, apoptosis, and inflammation
Published 2025-04-01“…Moreover, a 22 % fat level diet can significantly inhibit peroxisome proliferator-activated receptor alpha (PPARα)-related fatty acid transport and oxidation gene expression levels and improve PPARγ-related lipid synthesis gene expression levels to increase triglyceride levels in the serum and liver. …”
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973
The Multifaceted Roles of Myrrha in the Treatment of Breast Cancer: Potential Therapeutic Targets and Promises
Published 2024-12-01“…Method: The identified targets’ expression profiles were determined at the mRNA and protein levels using The Breast Cancer Gene-Expression Miner v5.0 (bcGen-ExMiner v5.0) and The Human Protein Atlas datasets, respectively. …”
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974
Comparative impact of tertiary lymphoid structures and tumor-infiltrating lymphocytes in cholangiocarcinoma
Published 2025-01-01“…TLSs were associated with “inflamed” tumors characterized by substantial immune infiltration, particularly involving T and B cells. Gene expression analyses identified significant upregulation of B cell-related genes in TLSs. …”
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975
Interactions between NAD+ metabolism and immune cell infiltration in ulcerative colitis: subtype identification and development of novel diagnostic models
Published 2025-02-01“…Weighted gene co-expression network analysis (WGCNA) combined with differential gene expression analysis was used to pinpoint specific NMRGs in UC. …”
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976
Placental malaria infection is associated with downregulation of STAT-6 and ANG-1 in decidual macrophages
Published 2025-02-01“…Notably, the gene expression levels of the transcription factor STAT-6 and angiogenic factor ANG-1 were significantly lower in infected placentas. …”
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977
Cloning and Expression Characteristics of BhARF4 Gene in Wax Gourd (Benincasa hispida)
Published 2024-11-01“…And the gene express specifically in different wax gourd materials.…”
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978
Peel of pumpkin (Cucurbita pepo) diets boost growth, digestive-absorptive functions, immune-antioxidant indices, and regulate immunomodulatory genes and mTOR/MAPK-P38/apoptosis sig...
Published 2025-03-01“…The current study examines the effects of feeding pumpkin (Cucurbita pepo) peel powder (CPP) on growth, digestive processes, immune-antioxidant parameters, and gene expression that regulates these processes in Nile tilapia (Oreochromis niloticus). …”
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979
RNA Polymerase RPOTp is Involved in C‐to‐U RNA Editing at Multiple Sites in Arabidopsis Chloroplasts
Published 2025-01-01“…Abstract RPOTp is the nuclear‐encoded plastid‐targeted RNA polymerase and plays a crucial role in chloroplast gene expression. Transcripts in plant organelles are altered by the conversion of cytidine (C) to uridine (U) at specific positions through RNA editing. …”
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980
Memory B cells and their transcriptomic profiles associated with belimumab resistance in systemic lupus erythematosus in the maintenance phase
Published 2025-02-01“…RNA-Seq of whole blood was performed, and gene expression was quantified. Immune cell type enrichment analysis estimated immune cell subtype proportions and gene expression in each subtype. …”
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