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861
A review of quorum-sensing and its role in mediating interkingdom interactions in the ocean
Published 2025-02-01“…Abstract Quorum sensing, first described in marine systems five decades ago, is a well-characterized chemical communication system used to coordinate bacterial gene expression and behavior; however, the impact of quorum sensing on interkingdom interactions has been vastly understudied. …”
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862
Epigenetic Modulation on Tau Phosphorylation in Alzheimer’s Disease
Published 2019-01-01“…Epigenetic modification refers to heritable alterations in gene expression that are not caused by direct changes in the DNA sequence of the gene. …”
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863
Plakoglobin: Role in Tumorigenesis and Metastasis
Published 2012-01-01“…The exact roles that plakoglobin plays during tumorigenesis and metastasis are not clear; however, recent evidence suggests that it may regulate gene expression, cell proliferation, apoptosis, invasion, and migration. …”
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864
Structural, Synaptic, and Epigenetic Dynamics of Enduring Memories
Published 2016-01-01“…In this review, we highlight three of the greatly addressed mechanisms that play a central role for a given memory to endure: the allocation of the memory to a given neuronal population and what brain areas are recruited for its storage; the structural changes that underlie memory persistence; and finally the epigenetic control of gene expression that might regulate and support memory perseverance. …”
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865
Molecular Basis of Triple Negative Breast Cancer and Implications for Therapy
Published 2012-01-01“…Recent genomewide gene expression and DNA sequencing studies indicate that this cancer type is composed of a molecularly heterogeneous group of diseases that carry multiple somatic mutations and genomic structural changes. …”
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866
Themes and Variations: Regulation of RpoN-Dependent Flagellar Genes across Diverse Bacterial Species
Published 2014-01-01“…Although the overall process of flagellar biogenesis is conserved among bacteria, the mechanisms used to regulate flagellar gene expression vary greatly among different bacterial species. …”
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867
Identification of Important Genes of Keratoconus and Construction of the Diagnostic Model
Published 2022-01-01“…GSE151631 and GSE77938 were downloaded from the comprehensive gene expression database (GEO). By using the random forest model (RF), support vector machine model (SVM), and generalized linear model (GLM), important immune-related genes were identified as biomarkers for KC diagnosis. …”
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868
PPARgamma-Dependent Control of Renin Expression: Molecular Mechanisms and Pathophysiological Relevance
Published 2013-01-01“…Furthermore, I discuss the need for generating of additional transgenic animal models which are more appropriate with regard to the role of the PPARgamma-dependent regulation of the renin gene expression in human diseases such as arterial hypertension and metabolic syndrome.…”
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869
Alterations of the Biochemical Pathways of Plants by the Air Pollutant Ozone: Which are the True Gauges of Injury?
Published 2007-01-01“…If these processes fail, past observations of ozone injury have indicated many physiological and metabolic changes then occur; most of these changes are likely to have been initiated at the level of gene expression, suggesting signal transduction. In the last decade considerable understanding of the biochemical process within plants has been developed. …”
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870
Alternative RNA Splicing in Cardiac Diseases
Published 2025-01-01“…Alternative splicing (AS), a critical process for gene expression regulation, allows a single precursor RNA to produce multiple transcript variants. …”
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871
D(—)–Lactic Acid Producing Probiotics, D(—)–Lactic Acidosis and Infants
Published 2004-01-01“…There is mounting evidence that ingestion of selected probiotics can modify disease morbidity for specific conditions affecting humans, and there is growing interest in the amelioration or prevention of disease with probiotics. Modulation in gene expression of the cellular elements of the intestinal mucosa and interbacterial interactions are leading theories as to the mechanism whereby probiotics can effect benefit for the host. …”
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872
Case report: Dupilumab-induced linear psoriasis: a rare presentation
Published 2025-01-01“…A 42 year-old male with prurigo nodularis treated with dupilumab showed a case of linear psoriasis, highlighting the potential of dupilumab to induce immune shift and chimeric gene expression.…”
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873
MicroRNAs in Development
Published 2006-01-01“…This review will describe our current understanding of how miRNAs regulate gene expression and will focus on the roles these noncoding RNAs play during the development of both invertebrate and vertebrate species.…”
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874
Summary of Known Genetic and Epigenetic Modification Contributed to Hypertension
Published 2023-01-01“…Reports suggest that genetic factors are estimated to be involved in approximately 30 to 50% of BP variation, and epigenetic marks are known to contribute to the initiation of the disease by influencing gene expression. Consequently, elucidating the genetic and epigenetic mediators associated with hypertension is essential for better discernment of its pathophysiology. …”
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875
Anopheles gambiae phagocytic hemocytes promote Plasmodium falciparum infection by regulating midgut epithelial integrity
Published 2025-02-01“…The mosquito’s hemocytes also control the midgut microbiota and immune gene expression. Our study unveils novel hemocyte functions that are exploited by the human malaria parasite to evade the mosquito’s immune system.…”
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876
Sensitivity of signaling pathway dynamics to plasmid transfection and its consequences
Published 2016-07-01“…In order to illustrate this, an original mathematical model of miRNA-mediated control of gene expression in the NF$\kappa$B pathway is presented. …”
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877
Uncovering Clinical Features of De Novo Philadelphia Positive Myelodysplasia
Published 2017-01-01“…Though not yet fully understood, there is an association between genetic abnormalities and defects in gene expression. The functional role for infrequent cytogenetic alteration remains unclear. …”
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878
The Transcribed-Ultraconserved Regions: A Novel Class of Long Noncoding RNAs Involved in Cancer Susceptibility
Published 2011-01-01“…Focus on such sequences has revealed numerous RNA subtypes with several functions in RNA processing and gene expression regulation, and deep sequencing studies imply that many remain to be discovered. …”
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879
François Gros : Une personnalité de premier plan, un homme secret
Published 2024-01-01“…I joined François Gros’ laboratory in 1975, to study mechanisms of gene expression in eukaryotes. Despite the lack of powerful tools, that would be brought later by genetic engineering, I obtained publishable results and was allowed to defend a third cycle thesis. …”
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880
Changes in the Expression of Mitochondrial Morphology-Related Genes during the Differentiation of Murine Embryonic Stem Cells
Published 2020-01-01“…During embryonic development, cells undergo changes in gene expression, signaling pathway activation/inactivation, metabolism, and intracellular organelle structures, which are mediated by mitochondria. …”
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