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761
Molecular mechanisms and comparative transcriptomics of diapause in two corn rootworm species (Diabrotica spp.)
Published 2025-01-01“…Comparative transcriptomic analyses between WCR and NCR indicated that while many gene expression changes were conserved across species, overall gene expression profiles were distinct, indicating that many transcriptional changes are species-specific, despite the close phylogenetic relationship and phenotypic similarity between these species. …”
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762
Study of Bone Marrow Mesenchymal and Tendon-Derived Stem Cells Transplantation on the Regenerating Effect of Achilles Tendon Ruptures in Rats
Published 2015-01-01“…For possible mechanism in tendon repair/regeneration through TDSCs and BMSCs, we measured Collagen-I (Col-I), Col-III gene expression level by RT-PCR, and Tenascin-C expression via immunofluorescent assay. …”
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763
Transcript Profiles of Stria Vascularis in Models of Waardenburg Syndrome
Published 2020-01-01“…Our data suggests that there is a significant difference on the gene expression and function between these two models.…”
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764
All-Trans Retinoic Acid Inhibits Bone Marrow Mesenchymal Stem Cell Commitment to Adipocytes via Upregulating FRA1 Signaling
Published 2020-01-01“…Compared with that in the atRA group, the si-fra1 + atRA also upregulated adipogenic gene expression. However, compared with si-fra1, si-fra1 + atRA significantly inhibited adipogenic differentiation. …”
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765
Tissue-friendly dentin treatments as a potential element in revascularization protocol (ex-vivo study)
Published 2025-02-01“…HEDP exhibited substantial calcium deposition and significantly upregulated BMP-2, TGF-β1, VEGF, and DSPP gene expression, surpassing other materials. Curcumin moderately promoted calcified nodule formation. …”
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766
A bidirectional Mendelian randomization study integrating genome-wide association studies, expression quantitative trait locus, and methylation quantitative trait locus data reveal...
Published 2025-02-01“…By incorporating consistent summary data-based Mendelian randomization associations between DNA methylation and smoke/Barrett’s esophagus, gene expression and smoke/Barrett’s esophagus, and DNA methylation and gene expression, we identified that the genetic variant-cg00935895-RBM43 (ENSG00000184898)-smoke/Barrett’s esophagus axis exerted an effect on smoke/Barrett’s esophagus by altering the DNA methylation level, which regulated the expression level of RBM43. …”
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767
Feature Selection in Cancer Classification: Utilizing Explainable Artificial Intelligence to Uncover Influential Genes in Machine Learning Models
Published 2024-12-01“…Additionally, the results suggest that the SHAP method can be effectively used as a feature selector in gene expression data. This approach not only enhances model transparency but also maintains high classification performance, highlighting its potential in identifying biologically relevant features that may serve as biomarkers for cancer diagnostics and treatment planning.…”
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768
Integration of Mendelian Randomization to explore the genetic influences of pediatric sepsis: a focus on RGL4, ATP9A, MAP3K7CL, and DDX11L2
Published 2025-01-01“…Abstract Objective This study aims to explore the genetic characteristics of pediatric sepsis through a combined analysis of multiple methods, including Mendelian Randomization (MR), differential gene expression analysis, and immune cell infiltration assessment. …”
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769
CaGe: A Web-Based Cancer Gene Annotation System for Cancer Genomics
Published 2012-03-01“…High-throughput genomic technologies (HGTs), including next-generation DNA sequencing (NGS), microarray, and serial analysis of gene expression (SAGE), have become effective experimental tools for cancer genomics to identify cancer-associated somatic genomic alterations and genes. …”
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770
Novel insights into immunopathogenesis and crucial biomarkers between primary open‐angle glaucoma and systemic lupus erythematosus
Published 2024-12-01“…The RT‐qPCR results confirmed the trend in gene expression. This study uncovered a new link between SLE and primary open‐angle glaucoma, identifying biomarkers and mechanisms of immunopathogenesis for future research and treatment strategies.…”
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771
Transcriptome Analysis of Interspecific Hybrid between Brassica napus and B. rapa Reveals Heterosis for Oil Rape Improvement
Published 2015-01-01“…A comparative transcriptome analysis for B. napus (AnAnCC genome), B. rapa (ArAr genome), and its hybrid F1 (AnArC genome) was carried out to reveal the possible molecular mechanisms of heterosis at the gene expression level. A total of 40,320 nonredundant unigenes were identified using B. rapa (AA genome) and B. oleracea (CC genome) as reference genomes. …”
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772
Construction of cuproptosis-related genes risk model predicts the prognosis of Uterine Corpus Endometrial Carcinoma
Published 2025-01-01“…Differential gene expression was determined using LIMMA analysis, and functional enrichment analysis was conducted on identified cuproptosis-related genes. …”
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773
Genetic Comparison of Stemness of Human Umbilical Cord and Dental Pulp
Published 2016-01-01“…This study focuses on gene expression patterns and functions in human umbilical cord (UC) and dental pulp (DP) containing mesenchymal stem cells (MSCs). …”
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774
Effects of adipose allograft matrix on viability of humeral head cartilage and rotator cuff tendon
Published 2025-01-01“…After 48 h, the tissues and cells were measured for cell viability, cell proliferation, extracellular matrix (ECM) and metalloproteinase (MMP) gene expression and for MMP, inflammatory cytokine, and growth factor concentrations. …”
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775
Targeting Acinetobacter baumannii resistance-nodulation-division efflux pump transcriptional regulators to combat antimicrobial resistance
Published 2025-01-01“…Abstract Regulatory elements controlling gene expression fine-tune bacterial responses to environmental cues, including antimicrobials, to optimize survival. …”
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776
X-Chromosome Inactivation and Related Diseases
Published 2022-01-01“…X-chromosome inactivation (XCI) is the form of dosage compensation in mammalian female cells to balance X-linked gene expression levels of the two sexes. Many diseases are related to XCI due to inactivation escape and skewing, and the symptoms and severity of these diseases also largely depend on the status of XCI. …”
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777
Combined Effects of Estrogen and Mechanical Loading on Anterior Cruciate Ligament Fibroblast Biosynthesis
Published 2005-01-01“…In a recent study, our group demonstrated a negative combined effect of estrogen and mechanical loading on the gene expression of major extracellular matrix component molecules in ACL fibroblasts.…”
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778
Combining Innovative Bioink and Low Cell Density for the Production of 3D-Bioprinted Cartilage Substitutes: A Pilot Study
Published 2020-01-01“…The chondrogenic effect of TGF-β1 was verified within the substitute on D28 by measuring chondrogenic gene expression and ECM synthesis (glycosaminoglycans and type II collagen) on D28. …”
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779
A Metabolic Gene Signature to Predict Overall Survival in Head and Neck Squamous Cell Carcinoma
Published 2020-01-01“…The availability of high-throughput expression data has made it possible to use global gene expression data to analyze the relationship between metabolic-related gene expression and clinical outcomes in HNSCC patients. …”
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780
Exercise induces dynamic changes in intra-articular metabolism and inflammation associated with remodeling of the infrapatellar fat pad in mice
Published 2025-01-01“…Exercise transiently increased cytokine and chemokine gene expression in synovium-IFP tissue, resolving within the first 5 days of exercise. …”
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