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601
ELOE: A WEB APPLICATION FOR ESTIMATION OF GENE TRANSLATION ELONGATION EFFICIENCY
Published 2015-01-01“…It is known that gene expression efficiency in an organism is regulated at many stages: transcription, translation, posttranslational protein modification, and others. …”
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602
Protein Profiling and Histone Deacetylation Activities in Somaclonal Variants of Oil Palm (Elaeis guineensis Jacq.)
Published 2013-01-01“…Higher HDAC activity was found in mantled leaf samples than in the phenotypically normal leaf samples, leading to a preliminary conclusion that histone deacetylation suppressed gene expression and contributed to the development of somaclonal variants.…”
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603
Mechanisms of miRNA-Mediated Gene Regulation from Common Downregulation to mRNA-Specific Upregulation
Published 2014-01-01“…Nevertheless, some studies revealed that miRNAs have the capability of activating gene expression directly or indirectly in respond to different cell types and conditions and in the presence of distinct cofactors. …”
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604
The Role of Epigenetic in Dental and Oral Regenerative Medicine by Different Types of Dental Stem Cells: A Comprehensive Overview
Published 2022-01-01“…Epigenetics describes changes in gene expression rather than changes in DNA and broadly happens in bone homeostasis, embryogenesis, stem cell fate, and disease development. …”
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605
The Interaction between Bmal1 and Per2 in Mouse BMSC Osteogenic Differentiation
Published 2018-01-01“…We also suppressed Per2 gene expression using an adenovirus vector harboring RNAi sequences, and similarly, the osteogenic differentiation ability of BMSCs was enhanced. …”
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606
Enrichment of rare alleles within epigenetic chromatin marks in the first intron
Published 2019-03-01“…In previous studies, we demonstrated that some sites in the first intron likely regulate gene expression. In the present work, we sought to further confirm the functional relevance of first intron sites by estimating the quantity of rare alleles in the first intron. …”
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607
Epigenome-wide association study of Chinese monozygotic twins identifies DNA methylation loci associated with estimated glomerular filtration rate
Published 2025-01-01“…The Genomic Regions Enrichment of Annotations Tool enriched biological functions and pathways. Gene expression profiling sequencing was employed to measure mRNA expression levels, and the GEE model was used to investigate the association between gene expression and eGFR. …”
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608
Human_SNP_TATAdb: a database of SNPs that statistically significantly change the affinity of the TATA-binding protein to human gene promoters: genome-wide analysis and use cases
Published 2023-12-01“…The results of the genome-wide analysis showed that the affinity of TBP for the promoter and the specificity of its binding site are statistically related to other characteristics of promoters important for the functional classification of promoters and the study of the features of differential gene expression.…”
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609
Induced Pluripotent Stem Cells Reduce Progression of Experimental Chronic Kidney Disease but Develop Wilms’ Tumors
Published 2017-01-01“…Renal function, histology, immunohistochemistry, and gene expression were studied. Implanted iPSs were tracked by the SRY gene expression analysis. …”
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610
Identification of core biomarkers for tuberculosis progression through bioinformatics analysis and in vitro research
Published 2025-01-01“…We define genes with a P-value less than 0.05 for the combined effect of infection and time on gene expression as those with altered expression patterns. …”
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611
Health effects of astaxanthin in the intestinal tract of yellow-feathered broilers
Published 2025-03-01“…In addition, IL-1β content and gene expression in broiler jejunal mucosa decreased, IL-6 gene expression decreased, and IL-4 content and gene expression increased (P < 0.05). …”
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612
Functional Analysis of Monkeypox and Interrelationship between Monkeypox and COVID-19 by Bioinformatic Analysis
Published 2023-01-01“…Based on the Gene Expression Omnibus database, we obtained 212 differentially expressed genes (DEGs) of GSE36854 and GSE21001 of monkeypox datasets. …”
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613
Small Molecule, Big Prospects: MicroRNA in Pregnancy and Its Complications
Published 2017-01-01“…MicroRNAs are small, noncoding RNA molecules that regulate target gene expression in the posttranscriptional level. Unlike siRNA, microRNAs are “fine-tuners” rather than “switches” in the regulation of gene expression; thus they play key roles in maintaining tissue homeostasis. …”
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614
Where Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability Disorders
Published 2016-01-01“…One of the most challenging questions in neuroscience is to dissect how learning and memory, the foundational pillars of cognition, are grounded in stable, yet plastic, gene expression states. All known epigenetic mechanisms such as DNA methylation and hydroxymethylation, histone modifications, chromatin remodelling, and noncoding RNAs regulate brain gene expression, both during neurodevelopment and in the adult brain in processes related to cognition. …”
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615
Association of Low Expression of NUMB in Peripheral Blood with Acute Myocardial Infarction
Published 2022-01-01“…Our study’s goal was to find out acute myocardial infarction (AMI) patients’ NUMB gene expression patterns and to evaluate its role as a diagnostic marker for AMI detection. …”
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616
Polysaccharides of St. John’s Wort Herb Stimulate NHDF Proliferation and NEHK Differentiation via Influence on Extracellular Structures and Signal Pathways
Published 2012-01-01“…The underlying mechanisms were investigated in gene expression studies. Polysaccharide fraction Hp1 was mainly composed of β-D-glucose. …”
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617
Comparative Neuroprotective Effects of Dexamethasone and Minocycline during Hepatic Encephalopathy
Published 2014-01-01“…ALI was associated with significant increases in all measured inflammatory mediators, oxidative stress, iNOS gene expression, and nitrite/nitrate. Both minocycline and dexamethasone significantly modulated the inflammatory changes and the oxidative/nitrosative stress associated with ALI. …”
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618
Optimum Combination of Insulin-Transferrin-Selenium and Fetal Bovine Serum for Culture of Rabbit Articular Chondrocytes in Three-Dimensional Alginate Scaffolds
Published 2009-01-01“…For a total culture of 3 weeks, phenotypic gene expression in chondrocyte-seeded hydrogels was maintained at high levels in medium with 1% ITS plus 2% FBS, while it was decreased to varying degrees in the other groups. …”
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619
Data Mining Mycobacterium tuberculosis Pathogenic Gene Transcription Factors and Their Regulatory Network Nodes
Published 2018-01-01“…In Mycobacterium tuberculosis, changes in gene expression are highly variable and involve many genes, so traditional single-gene screening of M. tuberculosis targets has been unable to meet the needs of clinical diagnosis. …”
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620
Collagen Modulates the Biological Characteristics of WJ-MSCs in Basal and Osteoinduced Conditions
Published 2022-01-01“…Gene expression profiles showed that COL not only maintained the pluripotency, self-renewal, and immunophenotype of WJ-MSCs but also primed cells toward lineage differentiations by upregulating BMP2 and TGFB1 genes. …”
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