Exome Sequencing: Mutilating Sensory Neuropathy with Spastic Paraplegia due to a Mutation in FAM134B Gene by Salma M. Wakil, Dorota Monies, Samya Hagos, Fahad Al-Ajlan, Josef Finsterer, Aisha Al Qahtani, Khushnooda Ramzan, Rawan Al Humaidy, Mohamed A. Al-Muhaizea, Brian Meyer, Saeed A. Bohlega

“…We employed homozygosity mapping and exome sequencing which is an efficient strategy to characterize the recessive genes, thus obtaining a rapid molecular diagnosis for genetically heterogeneous disorders like HSAN. …”
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MONet: cancer driver gene identification algorithm based on integrated analysis of multi-omics data and network models by Yingzan Ren, Tiantian Zhang, Jian Liu, Fubin Ma, Jiaxin Chen, Ponian Li, Guodong Xiao, Chuanqi Sun, Yusen Zhang

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Comprehensive Analysis of m5C RNA Methylation Regulator Genes in Clear Cell Renal Cell Carcinoma by Jiajin Wu, Chao Hou, Yuhao Wang, Zhongyuan Wang, Pu Li, Zengjun Wang

“…To reveal the relationships between the expression levels of m5C-related genes and the prognosis value in ccRCC, consensus clustering analysis was carried out. …”
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It Is All in the Genes: A Story of Unexpected Survival in a 67-Year-Old Male with Metastatic Pancreatic Cancer by Patsy W. P. Lee, Scott W. Strum, Elena Tsvetkova

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Influence of 16S Ribosomal RNA Gene Polymerase Chain Reaction and Sequencing on Antibiotic Management of Bone and Joint Infections by B Alraddadi, S Al-Azri, KR Forward

“…INTRODUCTION: Amplification of the 16S ribosomal RNA gene by polymerase chain reaction (PCR) followed by analysis of generated sequences can be an important adjunct to conventional cultures.…”
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INFORMATIONAL PORTAL «PLANT BIOTECHNOLOGY» – INTERNET RESOURCE TO SUPPORT EXPERIMENTS IN PLANT GENE ENGINEERING, GENETICS AND WHEAT BREEDING by A. V. Kochetov, O. G. Smirnova, S. M. Ibragimova, D. A. Rasskazov, D. A. Afonnikov, M. A. Genaev, A. V. Doroshkov, T. A. Pshenichnikova, A. V. Simonov, E. V. Morozova

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Clinical Diagnosis of X-Linked Spondyloepiphyseal Dysplasia Tarda and a Novel Missense Mutation in the Sedlin Gene (SEDL) by Lei Kong, Dongxu Wang, Shanshan Li, Chengsheng Zhang, Xiuyun Jiang, Qingbo Guan, Zhenlin Zhang, Fei Jing, Jin Xu

“…We identified the disease by gene sequencing in a Chinese pedigree with SEDT. …”
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Identification of tacrolimus-related genes in familial combined hyperlipidemia and development of a diagnostic model using bioinformatics analysis by Yuan Xu, Hongfei He, Haiyang Li

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Development of a marker panel for genotyping of domestic soybean cultivars for genes controlling the duration of vegetation and response to photoperiod by R. N. Perfil’ev, A. B. Shcherban, E. A. Salina

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Integration of transcriptomics and metabolomics data revealed role of insulin resistant SNW1 gene in the pathophysiology of gestational diabetes by Ravi Bhushan, Rimjhim Trivedi, Ritu Raj, Anjali Rani, Sangeeta Rai, Anima Tripathi, Shiv Govind Rawat, Ajay Kumar, Dinesh Kumar, Pawan K. Dubey

“…This study identified SNW1 as a novel insulin-resistant gene that induces hyperglycemia by elevating gluconeogenesis and decreasing glucose uptake. …”
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Seven Immune-Related Genes’ Prognostic Value and Correlation with Treatment Outcome in Head and Neck Squamous Cell Carcinoma by Rui Mu, Yuehong Shen, Chuanbin Guo, Xinyun Zhang, Hongyu Yang, Huijun Yang

“…The differentially expressed genes (DEGs) between HNSCC and normal samples were identified by multiple test corrections in TCGA database. …”
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Exploring potentially synthetic genes related to diarrhetic shellfish toxins production in Prorocentrum sp. via comparative transcriptomics by Danlin Zheng, Jingyi Cen, Peiliang Chen, Ligong Zou, Jian Zou, Qun Li, Songhui Lu

“…Additionally, we analyzed differential gene expression of PKSs in P. arenarium under nitrogen and phosphorus-limited conditions, revealing a correlation between specific PKSs gene expression patterns and okadaic acid (OA) content variations. …”
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VARIABILITY OF MITOCHONDRIAL CYTOCHROME OXYDASE SUBUNIT I GENE SEQUENCE IN SPECIES OF THE GENERA AEDES AND OCHLEROTATUS (DIPTERA: CULICIDAE) by N. V. Khrabrova, Yu. V. Andreeva, O. V. Vaulin, S. S. Alekseeva, A. K. Sibataev

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Utilizing bioinformatics and machine learning to identify CXCR4 gene-related therapeutic targets in diabetic foot ulcers by Hengyan Zhang, Ye Zhou, Heguo Yan, Changxing Huang, Licong Yang, Yangwen Liu

“…Finally, We analyzed the molecular pathways of CXCR4 in DFUs by Gene set enrichment analysis (GSEA).ResultsWe identified a total of 751 differential genes, of which 409 genes were significantly upregulated and 342 genes were downregulated in diabetic foot ulcer tissues. …”
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Genome-Wide Association and Transcriptome-Wide Association Studies Identify Novel Susceptibility Genes Contributing to Colorectal Cancer by Ruimin Yin, Binbin Song, Jingjing Wang, Chaodan Shao, Yufen Xu, HongGang Jiang

“…Transcriptome-wide association studies (TWAS) integrate summary statistics from CRC genome-wide association studies (GWAS) with gene expression data to prioritize these GWAS findings and uncover additional gene-trait correlations. …”
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Targeted correction of megabase-scale CNTN6 duplication in induced pluripotent stem cells and impacts on gene expression by Maria Gridina, Polina Orlova, Oleg Serov

“…Copy number variations of the human CNTN6 gene, resulting from megabase-scale microdeletions or microduplications in the 3p26.3 region, are frequently implicated in neurodevelopmental disorders such as intellectual disability and developmental delay. …”
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Comprehensive analysis reveals the tumor suppressor role of macrophage signature gene FCER1G in hepatocellular carcinoma by Deyu Kong, Yiping Zhang, Linxin Jiang, Nana Long, Chengcheng Wang, Min Qiu

“…Through principal component analysis and t-SNE dimensionality reduction, we identified 2,000 highly variable genes and per-formed clustering and annotation of 17 cell clusters, revealing 482 macrophage-related feature genes. …”
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Wnt/ β-catenin and CTNNB1 gene mutation in hepatocellular carcinoma, a case study in Egyptian patients by Ramy A. Abdelsalam, Ibrahim M. El-Shawaf, Azza Abdel-Aziz, Tarek A. Bismar, Shaimaa M. Yussif

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Genome-wide association scan and candidate gene analysis for seed coat color in sesame (Sesamum indicum L.) by Mohammed Elsafy, Wafa Badawi, Ahmed Ibrahim, Elamin Hafiz Baillo, Prabin Bajgain, Tilal Sayed Abdelhalim, Mahbubjon Rahmatov

“…GWAS identified significant SNPs associated with seed coat color traits, revealing key genomic regions on chromosomes 3, 6, 9, 12, and 13. Candidate gene analysis highlighted several genes, including DOF zinc finger proteins and WRKY transcription factors, which may play essential roles in pigment biosynthesis pathways. …”
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Mannose-Binding Lectin Promoter Polymorphisms and Gene Variants in Pulmonary Tuberculosis Patients from Cantabria (Northern Spain) by J.-Gonzalo Ocejo-Vinyals, Lucía Lavín-Alconero, Pablo Sánchez-Velasco, M.-Ángeles Guerrero-Alonso, Fernando Ausín, M.-Carmen Fariñas, Francisco Leyva-Cobián

“…We analysed the six promoter and structural mannose-binding lectin 2 gene variants in 107 patients with pulmonary tuberculosis and 441 healthy controls. …”
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