Behavioral, biochemical, immune, and histological responses of Nile tilapia (Oreochromis niloticus Linnaeus, 1758) to lead, mercury, and pendimethalin exposure: individual and comb... by Rasha M. Reda, Eman M. Zaki, Ahmed A. A. Aioub, Mohamed M. M. Metwally, Aya M. Yassin, Fatma Mahsoub

“…In all experimental groups, especially the MIX group, the levels of spleen pro-inflammatory cytokine genes were higher. The histopathological examination revealed marked lesions in the gills, liver, and brains in the form of inflammation, necrosis, and circulatory alterations. …”
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Importance of OsRac1 in Signalling of Pigm-1 Mediated Resistance to Rice Blast Disease by Dewei Yang, Niqing He, Fenghuang Huang, Jialin Chen, Minxiang Yu, Yidan Jin, Shaojun Lin, Shengping Li

“…This study offers crucial insights into how Pigm-1 protein activates downstream molecules and serves as a valuable reference for the molecular breeding of rice blast resistance genes, particularly <i>Pigm-1</i>.…”
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The biological control agent for bacterial canker of kiwifruit, in Aureo® Gold, is a strain of Aureobasidium pullulans identifiable by novel SCAR marker primers by Deirdre A. Cornish, Magan M. Schipper, Jenny M. Oldham, Janet Yu, Joel L. Vanneste

“…Analysis of the whole genome sequence of CG163 as well as a multi locus sequence analysis based on the ITS, ELO, EF-1α and β-tubulin genes indicate that CG163 is a strain of Aureobasidium pullulans. …”
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Single Nucleotide Polymorphisms in TLR4 Affect Susceptibility to Tuberculosis in Mexican Population from the State of Veracruz by Enrique Ortega, Sujhey Hernández-Bazán, Beatriz Sánchez-Hernández, Ileana Licona-Limón, Javier Fuentes-Dominguez

“…In this work, we performed a case-control study to determine if common single nucleotide polymorphisms (SNPs) in genes encoding TLRs 1, 2, 4, 6, and 10 are associated with susceptibility to develop active tuberculosis in population from the state of Veracruz, Mexico. …”
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Potential of emodepside for vector-borne disease control by Pattarapon Khemrattrakool, Thitipong Hongsuwong, Theerawit Phanphoowong, Patchara Sriwichai, Kittiyod Poovorawan, Joel Tarning, Kevin C. Kobylinski

“…Emodepside also has activity against Drosophila melanogaster SLO-1 channels. Orthologous SLO-1 genes are present in Anopheles gambiae and Aedes aegypti, suggesting that emodepside may have activity against mosquitoes. …”
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HBV DNA integration and somatic mutations in HCC patients with HBV-HCV dual infection reveals profiles intermediate between HBV- and HCV-related HCC by Chiao-Ling Li, Chia-Lang Hsu, You-Yu Lin, Ming-Chih Ho, Rey-Heng Hu, Sheng-Tai Tzeng, Ya-Chun Wang, Yasuhito Tanaka, Pei-Jer Chen, Shiou-Hwei Yeh

“…Common HCC somatic mutation analysis indicated HCV superinfection in HBCV-HCCs correlated with increased mutation rates in the telomerase reverse transcriptase (TERT) promoter and beta-catenin genes. Transcriptome analysis showed a prevalence of replicating HCV over HBV in HBCV-HCCs, with preexisting HBV exerting a proliferative role. …”
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Immortalized Mesenchymal Stem Cells: A Safe Cell Source for Cellular or Cell Membrane-Based Treatment of Glioma by Yuxuan Zhang, Jie Liu, Yunzhao Mo, Zetao Chen, Taoliang Chen, Yan Li, Yaofeng Zheng, Shaokang Deng, Xiangdong Xu, Huajian Chen, Haoqi He, Jiansheng Chen, Tao Jin, Xinlin Sun, Yiquan Ke, Jihui Wang

“…The im-MSCs were constructed by lentiviral transfection of genes. The proliferative capacity of im-MSCs and the proliferative phenotype of MSCs and MSCs co-cultured with glioma cells (U87) were measured using CCK-8 or EdU assays. …”
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Sinomenine attenuates uremia vascular calcification by miR-143-5p by Fengyi Yu, Zhong Peng, Ning Gao, Zixu Tang, Zihao Liao, Song Zhao, Shuzhu Zhong, Gloria Umwiza, Hong Huang, Wei Long, Zhangxiu He

“…We screened 9 differential expressed miRNAs and their predicted target genes. By qRT-PCR, we validated that the expression of rno-miR-143-5p was corresponding to our prediction. …”
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Diagnostic potential of CDK1 and STAT1 in acute kidney injury associated with gastrointestinal cancers: a bioinformatics-based study by Qiuwan Wei, Yiqing Shen, Yiren Tian, Yunzhi Ling

“…Differentially expressed genes (DEGs) associated with gastrointestinal cancer and kidney injury were identified through bioinformatics analysis. …”
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Antibiotic Resistance of Enterobacteriaceae in Microbiomes Associated with Poultry Farming by Anna S. Krivonogova, Irina M. Donnik, Albina G. Isaeva, Egor A. Loginov, Maxim V. Petropavlovskiy, Elisey N. Bespamyatnykh

“…Litter samples from both experimental and control groups demonstrated K. pneumoniae with severe phenotypic resistance to ciprofloxacin, as well as blaDHA genes. In broiler farming, maintenance and circulation of resistance agents depends on litter microbiota. …”
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Variability of daily feed intake as an indicator of resilience in Pietrain pigs by C. Casto-Rebollo, P. Nuñez, S. Gol, J. Reixach, N. Ibáñez-Escriche

“…Overlapping genomic regions were found for RIs and feed conversion ratio, highlighting DOCK1, SYK and SPTLC1 genes for their potential roles in modulating immune responses and/or metabolism. …”
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Assessing the success of breeding maize inbred lines with contrasting diferulate concentrations by Ana López-Malvar, Rosa Ana Malvar, Ana Butrón, Xose Carlos Souto, Rogelio Santiago

“…Conclusions Overall, we have obtained contrasting inbred lines with diferulates concentration, which could be uselful in further studies focussing in the identification of regions/genes predominantly involved in the hydroxycinnamate biosynthesis pathway and cell wall crosslinking network.…”
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Developing climate-resilient rice varieties (BRRI dhan97 and BRRI dhan99) suitable for salt-stress environments in Bangladesh. by Sanjoy K Debsharma, M Akhlasur Rahman, Mahmuda Khatun, Ribed F Disha, Nusrat Jahan, Md Ruhul Quddus, Hasina Khatun, Sharifa S Dipti, Md Ibrahim, K M Iftekharuddaula, Md Shahjahan Kabir

“…Among them, HHZ5-DT20-DT2-DT1 and IR83484-3-B-7-1-1-1 harbored eight and four QTL/genes that regulate the valuable traits revealed through 20 SNP genotyping. …”
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Kojic Acid Derivative as an Antimitotic Agent That Selectively Kills Tumour Cells by Giuseppina Pichiri, Marco Piludu, Terenzio Congiu, Nicole Grandi, Pierpaolo Coni, Monica Piras, Mariusz Jaremko, Joanna Izabela Lachowicz

“…NGS investigation showed differentiated expressions of genes involved in mitosis and apoptosis processes. …”
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Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Deliver miR-21 to Promote Corneal Epithelial Wound Healing through PTEN/PI3K/Akt Pathway by Xiaolong Liu, Xuran Li, Guangyuan Wu, Pengfei Qi, Yanyan Zhang, Zhiyu Liu, Xinyue Li, Yu Yu, Xiangmei Ye, Yang Li, Dongguang Yang, Yueqiu Teng, Ce Shi, Xin Jin, Sen Qi, Yuting Liu, Shudan Wang, Ying Liu, Fenglin Cao, Qingran Kong, Zhenkun Wang, Hong Zhang

“…Full-length transcriptome sequencing was performed to identify the differentially expressed genes associated with HUMSC-sEVs treatment, followed by validation via real-time PCR and Western blot. …”
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Untargeted metabolomics analysis of glycerophospholipid metabolism in very low birth weight infants administered multiple oil lipid emulsions by Xiaoyan Zeng, Tao Yu, Luping Xia, Zhiqiang Ruan

“…Functional annotation of the top 30 differential metabolites, ranked by VIP value, was conducted using the Kyoto Encyclopedia of Genes and Genomes (KEGG) database. Subsequently, enrichment and topological analyses were conducted with MetaboAnalyst software to identify key metabolic pathways. …”
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Blast‐Overpressure Induced Modulation of PARP‐SIRT‐NRF2 Axis in Stress Signaling of Astrocytes and Microglia by Vijaya Prakash Krishnan Muthaiah, Kathiravan Kaliyappan, Ramkumar Thiayagarajan, Supriya Mahajan, Krishnamoorthy Gunasekaran

“…Results As a result of NAD+ being a common substrate for PARP1 and Sirtuins, we found the decreased expression of SIRT1, SIRT3, and NRF2, a central transcriptional regulator for the expression of antioxidant genes. We found that ATP levels were elevated post‐BOP from both glycolysis and oxidative phosphorylation (OXPHOS), an increase of ATP by glycolysis more significant than OXPHOS source, indicating the proinflammation post‐BOP. …”
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Enfermedad cerebrovascular y aterosclerosis en pacientes angolanos by Marelys Castro Iglesias, Danay Castro Iglesias, Janet de las Mercedes Seoane Piedra, Loida Torres Pérez, Claudia Aguirre Castro

“…Se han identificado un número considerable de genes involucrados en la inflamación, el sistema renina-angiotensina y el metabolismo lipídico. …”
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Pheochromocytoma in Congenital Cyanotic Heart Disease by Carmen Aresta, Gianfranco Butera, Antonietta Tufano, Giorgia Grassi, Livio Luzi, Stefano Benedini

“…Screening for germline mutations did not show any genes mutation (investigated mutations: RET, TMEM127, MAX, SDHD, SDHC, SDHB, SDHAF2, SDHA, and VHL). …”
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Insights into incompatible plasmids in multidrug-resistant Raoultella superbugs by Jiao Feng, Changxin Wu, Dongsheng Zhou, Lingfei Hu, Kai Mu, Zhe Yin

“…Abstract The emergence of multidrug-resistant (MDR) Raoultella isolates is linked to the acquisition of antibiotic resistance genes (ARGs) with plasmids playing a pivotal role in this process. …”
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