A novel roseosiphovirus infecting dinoroseobacter shibae DFL12T represents a new genus by Nana Wei, Longfei Lu, Yingying Li, Bo Ding, Lanlan Cai, Yunlan Yang

“…Notably, seven auxiliary metabolic genes (AMGs), including those related to phosphate metabolism and queuosine biosynthesis, were identified. …”
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Promiscuous Chemokine Antagonist (BKT130) Suppresses Laser-Induced Choroidal Neovascularization by Inhibition of Monocyte Recruitment by Shira Hagbi-Levi, Michal Abraham, Liran Tiosano, Batya Rinsky, Michelle Grunin, Orly Eizenberg, Amnon Peled, Itay Chowers

“…Quantification of CD11b+ cell in the CNV area was performed, and mRNA levels of genes implicated in CNV growth were measured in the retina and RPE-choroid. …”
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NF-κB-Inducing Kinase Is Essential for Effective c-Rel Transactivation and Binding to the <i>Il12b</i> Promoter in Macrophages by Natalia Cuesta, Anna D. Staniszewska, Cristóbal Moreno, Carmen Punzón, Manuel Fresno

“…This study investigates the role of NIK in activating specific inflammatory genes in macrophages, focusing on the effect of a mutation in NIK found in alymphoplasia (<i>aly</i>/<i>aly</i>) mice. …”
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Combined therapy of human amnion-derived mesenchymal stem cells and scalp acupuncture alleviates brain damage in a rat model of cerebral palsy by Yu Zhou, Xu-Huan Li, Lu-Na He, Li-Na Wang, Jing Zang, Dong-Ming Wang, Jing Gao, Xue-feng Yu

“…Neurobehavioral function was assessed using the Bederson score, and brain tissues were analyzed using hematoxylin and eosin (H&E) staining, TUNEL staining, and RT-qPCR for apoptosis-related genes. Results: The CP group exhibited significant neurobehavioral deficits and increased apoptosis. …”
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Endothelial cell Piezo1 promotes vascular smooth muscle cell differentiation on large arteries by Javier Abello, Ying Yin, Yonghui Zhao, Josh Maurer, Jihui Lee, Cherokee Bodell, Jahmiera Richee, Abigail J. Clevenger, Zarek Burton, Megan E. Goeckel, Michelle Lin, Stephanie Grainger, Carmen M. Halabi, Shreya A. Raghavan, Rajan Sah, Amber N. Stratman

“…To determine the underlying mechanism, we used in vitro modeling assays to demonstrate that differential sensing of pulsatile versus laminar flow forces across endothelial cells changes the expression of mural cell differentiation genes. Together, our findings suggest a crucial role for EC Piezo1 in sensing force within large arteries to mediate mural cell differentiation and stabilization of the arterial vasculature.…”
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Diversity and Plant Growth-Promoting Properties of <i>Rhodiola rosea</i> Root Endophytic Bacteria by Inga Tamošiūnė, Muhammad Fahad Hakim, Odeta Buzaitė, Vidmantas Stanys, Jurgita Vinskienė, Elena Andriūnaitė, Danas Baniulis

“…Screening for functional genes related to the nitrogen cycle, phosphorus mineralisation or dissolution, and traits associated with nitrogen fixation (56% of isolates), siderophore production (40%), inorganic phosphorus solubilisation (30%), and production of indole-related compounds (51%) led to the classification of the isolates into 16 distinct clusters. …”
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Human Chorionic Plate-Derived Mesenchymal Stem Cells Restore Hepatic Lipid Metabolism in a Rat Model of Bile Duct Ligation by Yun Bin Lee, Jong Ho Choi, Eun Nam Kim, Jin Seok, Hyun-Jung Lee, Jung-Hwan Yoon, Gi Jin Kim

“…The expression levels of genes involved in intracellular lipid uptake, including long-chain fatty acyl-CoA synthetases and fatty acid transport proteins, were decreased in rats after BDL; however, they were not significantly changed by subsequent CP-MSC transplantation. …”
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Wheat Leaf Rust Effector Pt48115 Localized in the Chloroplasts and Suppressed Wheat Immunity by Lulu Song, Liping Cui, Hao Li, Na Zhang, Wenxiang Yang

“…<i>Pt</i> acquires nutrients from host cells via haustoria and secretes effector proteins to modify and regulate the expression of host disease resistance genes, thereby facilitating pathogen growth and reproduction. …”
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Expanding the clinical spectrum of 19p13.3 microduplication syndrome: a case report highlighting nephrotic syndrome and literature review by Wenjie Sun, Hong Yan, Mengxin Sun, Jie Wang, Kunxia Li

“…CMA results showed a 3.6 Mb fragment duplication (copy number: 3) in the chr19p13.3 region, containing 127 protein-coding genes (including CELF5, NFIC, SMIM24, PIAS4, ATCAY, MAP2K2, and ZBTB7A). …”
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Propofol Regulates ER Stress to Inhibit Tumour Growth and Sensitize Osteosarcoma to Doxorubicin by Hua Wei, Xinhui Du, Huaping Zhao, Peipei Sun, Jianjun Yang

“…Differential expressed genes after propofol treatment were obtained and functionally assessed with bioinformatic tools. …”
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Effective sources of powdery mildew resistance among spring bread wheat for the northwest of the Russian Federation by T. V. Lebedeva, A. N. Brykova, E. V. Zuev

“…Its progress is determined by new sources of effective resistance genes and their incorporation into promising spring bread wheat cultivars. …”
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Long noncoding RNAs predict the survival of patients with colorectal cancer as revealed by constructing an endogenous RNA network using bioinformation analysis by Hui Zhang, Zhuo Wang, Jianzhong Wu, Rong Ma, Jifeng Feng

“…Functional enrichment analysis suggested that the target genes of the ceRNA network may be involved in the pathways related to cancer, including the signaling pathway that regulates the pluripotency of stem cells, wnt signaling pathway, hippo signaling pathway, basal cell carcinoma, and colorectal cancer. …”
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Factors associated with early-onset androgenetic alopecia: A scoping review. by Li-Ping Liu, Mary Adumo Wariboko, Xiao Hu, Zi-Han Wang, Qian Wu, Yu-Mei Li

“…Early-onset AGA may also be associated with hormonal profiles, 5α-reductase enzyme activity, androgen receptor genes, and some susceptibility loci. Comorbidities investigated included MetS, cardiovascular disease, insulin resistance, dyslipidemia, and Parkinson's disease. …”
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Multiomic quantification of the KRAS mutation dosage improves the preoperative prediction of survival and recurrence in patients with pancreatic ductal adenocarcinoma by Won-Gun Yun, Daeun Kim, Youngmin Han, Wooil Kwon, Seong-Geun Lee, Jin-Young Jang, Daechan Park

“…For clinical use, it is necessary to focus on key genes and integrate them with relevant clinical variables. …”
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Progress in the Management of Retinal Detachment Associated With Morning Glory Syndrome by Wu S, Wang W, Liu L, Wang W, Jiang K, Peng C, Sun H, Zhang J

“…The etiology of MGS is not fully understood but has been associated with genetic factors, particularly mutations in the PAX6 and PAX2 genes, which play critical roles in eye development. …”
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Introgression of common wheat lines with genetic material of Agropyron glaucum by R. O. Davoyan, I. V. Bebyakina, E. R. Davoyan, A. N. Zinchenco, Y. S. Zubanova, D. S. Mikov

“…&amp; Schult is a valuable source of genes for resistance to diseases, frost resistance, and salt tolerance. …”
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The collaborative cross mouse for studying the effect of host genetic background on memory impairments due to obesity and diabetes by Avia Paz, Kareem Midlej, Osayd Zohud, Iqbal M. Lone, Fuad A. Iraqi

“…Conclusions Our study establishes a foundation for future quantitative trait loci mapping using CC lines and identifying genes underlying the comorbidity of Alzheimer's disease (AD), caused by obesity and T2D. …”
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Evaluation of genetic differences between two autochthonous Spanish cattle breeds by Paola E. Milia, Alberto Cesarani, Clara Diaz, Cristina Meneses, Juan Carlos Parejo, Laura Falchi, Nicolò P. P. Macciotta, Corrado Dimauro

“…Among markers selected by both FST and CDA, the top 10 discriminant SNPs were mapped to genomic regions harbouring genes involved in coat colour, behaviour, and morphological traits. …”
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The left amygdala is genetically sexually-dimorphic: multi-omics analysis of structural MRI volumes by Yuanyuan Gui, Geyu Zhou, Shuya Cui, Hongyu Li, Hui Lu, Hongyu Zhao

“…We also found several sex-differentially expressed genes in the amygdala. These findings not only advanced the current knowledge of genetic basis of sex differences in brain anatomy, but also presented an important clue for future research on the mechanism of sex differences in mental disorders and targeted treatments.…”
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Exploring the Hepatoprotective Effect of Agaricus bisporus Based on Network Pharmacology by WANG Jie, WANG Jinmei, LIU Hui, LIU Xuguang, GUO Wenjing, HE Hongping

“…Detection of the mRNA and protein expression levels of relevant genes was performed using real-time quantitative polymerase chain reaction (PCR) and Western blot techniques, showing that compared with the model group, the expression of the Bcl-2 in the high-dose group significantly increased (P < 0.001), while the expression of MYC, NF-κB1, RELA and MMP9 significantly decreased (P < 0.01). …”
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