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10921
Investigation of Intestinal Microbes of Five Zokor Species Based on 16S rRNA Sequences
Published 2024-12-01“…PICRUSt metagenome predictions revealed enriched microbial genes for carbohydrate and amino acid metabolism in <i>E. cansus</i> and <i>E. smithi</i>, and for cofactor and vitamin metabolism as well as glycan biosynthesis and metabolism in <i>E. rothschildi</i>, <i>M. aspalax</i>, and <i>M. psilurus</i>. …”
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10922
The beneficial effects of curcumin on aging and age-related diseases: from oxidative stress to antioxidant mechanisms, brain health and apoptosis
Published 2025-01-01“…Furthermore, curcumin has a potent inhibitory effect on the activity of nuclear factor kappa B (NF-κB) and cyclooxygenase-2 (COX-2), which are involved in the overexpression of antiapoptosis genes such as Bcl-2. It can also attenuate the regulation of antiapoptosis phosphoinositide 3-kinases (PI3K) signaling and increase the expression of mitogen-activated protein kinases (MAPKs) to induce endogenous production of ROS. …”
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10923
Localization of the quantitative trait loci related to lodging resistance in spring bread wheat (<i>Triticum aestivum</i> L.)
Published 2022-11-01“…The results obtained suggest that the regions of 700–711 and 597–618 Mb in chromosomes 3A and 6A, respectively, may contain clusters of genes that affect lodging resistance and plant height. …”
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10924
KAI2-dependent signaling controls vegetative reproduction in Marchantia polymorpha through activation of LOG-mediated cytokinin synthesis (14)
Published 2025-02-01“…In this study, we identify genes working downstream of KAI2-dependent signaling in M. polymorpha. …”
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10925
Long non-coding RNA TINCR suppresses growth and epithelial-mesenchymal transition by inhibiting Wnt/β-catenin signaling pathway in human pancreatic cancer PANC-1 cells: Insights fr...
Published 2024-03-01“…Ectopic expression of TINCR in PANC-1 cells was induced to evaluate the effects on cell viability and apoptosis, examining the apoptotic genes Bax and Bcl-2. Migration and invasion assays were used to measure the impact of TINCR on these cellular processes. …”
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10926
Preliminary In Vitro Evaluation of the Probiotic Potential of the Bacteriocinogenic Strain Enterococcus lactis PMD74 Isolated from Ezine Cheese
Published 2019-01-01“…The antimicrobial activity of the proteinaceous compound was calculated as 6400 AU·mL−1 by the critical dilution method against E. faecalis ATTC 29212. γ-Hemolytic PMD74 was observed to be sensitive to vancomycin, ampicillin, penicillin, gentamicin, tetracycline, chloramphenicol, and tylosin. Among the four genes tested, E. lactis PMD74 was observed to be positive for three virulence determinants, ace, sprE, and gelE, and negative for esp. …”
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10927
Testing Phylogenetic Placement Accuracy of DNA Barcode Sequences on a Fish Backbone Tree: Implications of Backbone Tree Completeness and Species Representation
Published 2025-01-01“…Using a dataset comprising 27 genes and 4520 species of bony fishes, we assessed the accuracy of phylogenetic inference by “placing” COI sequences onto backbone trees. …”
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10928
Significant abundance of bacterial flagellin and expression of its surface localized receptor toll-like receptor 5 and cytokine interleukin-22 in South African infants with poor or...
Published 2025-01-01“…The abundance of flagellin and expression of flagellin-encoding fliC, TLR5 and NLRC4, IL-22 and IL-18 genes was determined by qPCR. There were no differences in the abundance of flagellin between vaccine shedders and non-shedders (p = 0.15). …”
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10929
Comparative Analysis on Single- and Multiherb Strategies in Coronary Artery Atherosclerosis Therapy
Published 2021-01-01“…Nitric oxide-associated carbonate dehydratase activity and nitrogen metabolism are tacitly enriched by target corresponding genes with statistical significance in four strategies. …”
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10930
Distribution and frequency of genetic mutations in three insecticide targets in field populations of Culex tritaeniorhynchus in Mianyang City, Sichuan Province, China
Published 2025-02-01“…In the study, a total of 314 adults of Cx. tritaeniorhynchus, collected from 6 sites across Mianyang City, were inspected for resistance-conferring mutations in three genes encoding voltage-gated sodium channel (VGSC), Gamma-aminobutyric acid (GABA) receptor Rdl subunit (Rdl), and acetylcholinesterase (AChE) by DNA Sanger sequencing. …”
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10931
Predominance of OXA-48 Carbapenemase-Producing Enterobacterales in a Moroccan Hospital
Published 2023-01-01“…Molecular screening of carbapenemases genes (OXA-48, NDM, blaKPC, blaIMP, blaVIM, and blaOXA-24, blaOXA-23, OXA-51, OXA-58) using conventional multiplex PCR assays was also performed on 143 isolates. …”
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10932
A Novel Rat Infant Model of Medial Temporal Lobe Epilepsy Reveals New Insight into the Molecular Biology and Epileptogenesis in the Developing Brain
Published 2024-01-01“…We further analyzed selected candidate genes potentially relevant to epileptogenesis using a RT-qPCR approach. …”
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10933
The effect of the <i>Ant25</i>, <i>Ant26</i> and <i>Ant27</i> loci controlling proanthocyanidin synthesis in barley (<i>Hordeum vulgare</i> L.) grain on plant growth and developmen...
Published 2024-07-01“…Mutants at the Ant25, Ant26 and Ant27 loci with unknown molecular functions can be used as donors of recessive alleles of the genes specifically controlling proanthocyanidin synthesis in barley grain. …”
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10934
Identification of KIFC1 as an independent prognostic marker in renal clear cell carcinoma correlates with tumor proliferation and immune infiltration
Published 2023-10-01“…However, there was a significant positive relationship between CD8 + T cells and numerous immune checkpoint genes. CD8 + T cells in tumors from the KIFC1 high expression group were at the dysregulated state. …”
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10935
Genetics and pathophysiology of low-renin arterial hypertension
Published 2019-01-01“…Also, several oligogenic forms of low-renin hypertension were studied, some of which are associated with the hyperproduction of aldosterone, but in the others the development of low-renin hypertension was associated with mutations of genes involved in regulation of the functioning of the kidney ion channels. …”
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10936
Clinical considerations on antimicrobial resistance potential of complex microbiological samples
Published 2025-01-01“…Next and third generation sequencing technologies allow the identification of antimicrobial resistance genes (ARGs) present in a bacterial community. Using this metagenomic approach, we can map the antimicrobial resistance potential (AMRP) of a complex, multi-bacterial microbial sample. …”
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10937
Insights into the toxic impact of long-term exposure to diethyl phthalate on commercially important species Catla (Labeo catla)
Published 2025-01-01“…Results DEP exposure to 1/10th (1.62 mg/L) and 1/50th (0.32 mg/L) LC50 dose for 30 days to Catla revealed that it stimulated the expression of kisspeptin (Kiss 1 and Kiss 2) genes in the hypothalamus, leading to an increased GnRH concentration (36.75%) in the higher dose. …”
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10938
A Survey of SNP Data Analysis
Published 2018-09-01“…SNPs have been used to successfully identify defective genes that cause Mendelian diseases. However, most common human diseases are complex and are caused by multiple SNPs. …”
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10939
Exploring genetic structures and shared sites between alcohol, cheese intake, and inflammatory bowel disease
Published 2025-01-01“…Furthermore, both conjFDR and MTAG analyses identified multiple shared genetic loci, with nine genes (Y_RNA, DENND1B, GCKR, KPNA7, CLN3, SLC39A8, FUT2, ERAP2, and SMAD3) being.ConclusionThe present study provides genetic evidence supporting the comorbidity of alcohol and cheese intake with IBD, offering novel insights into potential strategies for the prevention and treatment of IBD through the modulation of alcohol and cheese consumption.…”
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10940
Assessment of microbial diversity and antimicrobial resistance in raw camel milk: Genomic and phenotypic analysis of Kharai and Kutchi breeds of Gujarat, India
Published 2025-03-01“…The genotypic analysis, performed via nanopore metagenomic sequencing, revealed the presence of various antimicrobial resistance genes (ARGs). In the Kharai breed 58 ARGs were detected, majority of them conferring resistance to fluoroquinolones, tetracycline, macrolides, and colistin. …”
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