Renin-Angiotensin System Gene Variants and Type 2 Diabetes Mellitus: Influence of Angiotensinogen by Siew Mei Joyce-Tan, Shamsul Mohd Zain, Munavvar Zubaid Abdul Sattar, Nor Azizan Abdullah

“…However, some variants are not included in the GWAS to avoid penalty in multiple hypothetic testing. Thus, candidate gene approach is still useful even at GWAS era. This study attempted to assess whether genetic variations in the renin-angiotensin system (RAS) and their gene interactions are associated with T2DM risk. …”
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Corrigendum to “Identification of Differentially Expressed Genes in Pituitary Adenomas by Integrating Analysis of Microarray Data” by Peng Zhao, Wei Hu, Hongyun Wang, Shengyuan Yu, Chuzhong Li, Jiwei Bai, Songbai Gui, Yazhuo Zhang

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Continuous and Discrete Similarity Coefficient for Identifying Essential Proteins Using Gene Expression Data by Jiancheng Zhong, Zuohang Qu, Ying Zhong, Chao Tang, Yi Pan

“…In this work, we discretized gene expression data and used the discrete similarities of the gene expression spectrum to eliminate noise fluctuation. …”
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Light-regulated microRNAs shape dynamic gene expression in the zebrafish circadian clock. by Zuo Wang, Shuang Wang, Yi Bi, Alessandra Boiti, Shengxiang Zhang, Daniela Vallone, Xianyong Lan, Nicholas S Foulkes, Haiyu Zhao

“…Importantly, we identified sets of light-regulated miRNAs, with many regulatory targets representing light-inducible mRNAs including circadian clock genes and genes involved in redox homeostasis. We subsequently focused on the light-responsive miR-204-3-3p and miR-430a-3p which are predicted to regulate the expression of cryptochrome genes (cry1a and cry1b). …”
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Cloning and Expression Characteristics of BhARF4 Gene in Wax Gourd (Benincasa hispida) by Xiaoxin CHENG, Xuling ZHAI, Jinqiang YAN, Baochen WANG, Renliang MO, Wenrui LIU, Zhiming WU, Biao JIANG

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RECONSTRUCTION OF MECHANISMS REGULATING THE EXPRESSION OF THE ESCHERICHIA COLI YFIA GENE UNDER STRESS CONDITIONS by T. M. Khlebodarova, D. Yu. Oshchepkov, N. V. Tikunova, I. V. Babkin, A. D. Gruzdev, V. A. Likhoshvai

“…The regulatory region of the Escherichia coli yfiA gene was reconstructed by using the SiteCon web resource and mathematical modeling, and its expression complexity under oxidative stress was assessed. …”
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Integrating representation learning, permutation, and optimization to detect lineage-related gene expression patterns by Hannah M. Schlüter, Caroline Uhler

“…Such datasets provide opportunities to compare gene expression memory maintenance through lineage branching and pinpoint critical genes in these processes. …”
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Nuclear talin-1 provides a bridge between cell adhesion and gene expression by Alejandro J. Da Silva, Hendrik S.E. Hästbacka, Mikael C. Puustinen, Jenny C. Pessa, Jens C. Luoto, Erika Sundström, Benjamin T. Goult, Guillaume Jacquemet, Eva Henriksson, Lea Sistonen

“…Our findings revealed that the accumulation of nuclear TLN1 alters the expression of a subset of genes and impairs the formation of cell-cell clusters. …”
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Corrigendum to “Two Mutations in Surfactant Protein C Gene Associated with Neonatal Respiratory Distress” by Anna Tarocco, Elisa Ballardini, Maria Raffaella Contiero, Giampaolo Garani, Silvia Fanaro

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Plant miRNAs for Improved Gene Regulation in a Wide Range of Human Cancers by Maksym Zoziuk, Vittorio Colizzi, Pavlo Krysenko, Maurizio Mattei, Roberta Bernardini, Fabio Massimo Zanzotto, Stefano Marini, Dmitri Koroliouk

“…Determining the relationships between miRNA expression, target genes, and cancer development is critical to cancer research. …”
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Data Mining Mycobacterium tuberculosis Pathogenic Gene Transcription Factors and Their Regulatory Network Nodes by Guangxin Yuan, Yu Bai, Yuhang Zhang, Guangyu Xu

“…In Mycobacterium tuberculosis, changes in gene expression are highly variable and involve many genes, so traditional single-gene screening of M. tuberculosis targets has been unable to meet the needs of clinical diagnosis. …”
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Statistical and machine learning based platform-independent key genes identification for hepatocellular carcinoma. by Md Al Mehedi Hasan, Md Maniruzzaman, Jie Huang, Jungpil Shin

“…Existing studies used genetic datasets, taken from various platforms, but focused only on common differentially expressed genes (DEGs) across platforms. Consequently, these studies may missed some important genes in the investigation of HCC. …”
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Bioinformatic Prediction of Novel microRNAs Encoded in Krüppel-like Factor 4 Gene by Mina Zahiri, Maryam Hassanlou, Amir-Reza Javanmard, Nooshin Bijari

“…MicroRNAs are small non-coding RNAs that can regulate gene expression that affects various cellular processes. …”
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Molecular detection of the hpmA and ureA genes in clinical Proteus mirabilis isolates by Rosa Kareem Shameel, Marwa Hameed M. Alkhafaji

“…The molecular technique showed that the ureA and hpmA genes associated with virulence factor hemolysin (hpmA) and urease (ureA) genes are necessary for causing urinary tract infections …”
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Identification and Development of Synovial B-Cell-Related Genes Diagnostic Signature for Rheumatoid Arthritis by Jifeng Tang, Jinfang Xia, Huiming Sheng, Jinpiao Lin

“…The aim of the study was to investigate the landscape of B-cell-related gene expression profiling in rheumatoid arthritis (RA) synovium and explore the biological and clinical significance of these genes in RA. …”
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Rat Sarcoma Virus Family Genes in Acute Myeloid Leukemia: Pathogenetic and Clinical Implications by Shaimaa Khattab, Adriatik Berisha, Natalia Baran, Pier Paolo Piccaluga

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Interleukin-18 Gene Polymorphisms and Rheumatoid Arthritis Susceptibility: An Umbrella Review of Meta-Analyses by Yuehong Chen, Yali Ye, Huan Liu, Zhongling Luo, Qianwei Li, Qibing Xie

“…This study systematically analyzes the association between interleukin-18 (IL-18) gene polymorphisms and rheumatoid arthritis (RA) susceptibility. …”
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Influence of N6-Methyladenosine Modification Gene HNRNPC on Cell Phenotype in Parkinson’s Disease by Wei Quan, Jia Li, Li Liu, Qinghui Zhang, Yidan Qin, Xiaochen Pei, Jiajun Chen

“…We analyzed the differentially expressed genes and function enrichment analysis of the two sets of data and found that the expression of the m6A-modification gene HNRNPC was significantly downregulated in the PD group, and it played an important role in DNA metabolism, RNA metabolism, and RNA processing and may be involved in PD. …”
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Gene Expression Profiling of the Sciatic Nerve in Streptozotocin-Induced Diabetic Rats with Peripheral Neuropathy by Yiji Tu, Zenggan Chen, Feng Zhang, Zhenglin Di, Junhui Zhang, Li Cai

“…Microarray was performed on the sciatic nerve tissues from control rats and DPN rats at then6th week after diabetes induction, and differentially expressed genes (DEGs) between them were identified and applied for further bioinformatic analyses. …”
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Correlation among blastocoel fluid DNA level, apoptotic genes expression and preimplantation aneuploidy by Fattaneh Khajehoseini, Zahra Noormohammadi, Poopak Eftekhari-Yazdi, Hamid Gourabi, Reza Pazhoomand, Shirzad Hosseinishenatal, Masood Bazrgar

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