Showing 501 - 520 results of 11,465 for search '"gene"', query time: 0.13s Refine Results
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    The role of isoniazid dosage and NAT2 gene polymorphism in the treatment of tuberculous meningitis by Yi Jian, Yuhang Bao, Fashuang Yang, Mei Zhu

    Published 2025-01-01
    “…This study seeks to explore the impact of varying INH dosages and NAT2 gene polymorphisms on TBM treatment, contributing new insights to improve clinical management and patient prognosis.MethodsPatients with TBM hospitalized between July 2020 and December 2022 were categorized into two groups based on INH dosage: the standard-dose group (300 mg/day) and the high-dose group (600 mg/day). …”
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  3. 503

    Influence of MHC on genetic diversity and testicular expression of linked olfactory receptor genes by Mingue Kang, Byeongyong Ahn, Jae Yeol Shin, Hye-Sun Cho, Jongan Lee, Chankyu Park

    Published 2025-02-01
    “…To explore the genetic diversity of MHC-linked OR genes and their connection to MHC genes, we conducted a combined haplotype analysis of MHC-linked OR and MHC class I genes to determine the influence of MHC on OR diversity, which could be associated with MHC-based mate selection. …”
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    Case Report: Homozygous C677T MTHFR Gene Mutation in Male with Hypogonadism by Rami Salameh, Mumtaheena Miah, Catherine Anastasopoulou

    Published 2020-01-01
    “…Also, it shows possible association between MTHFR gene mutation and male hypogonadism.…”
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  7. 507

    Influence of AGTR1 and ABCB1 Gene Polymorphism on the Curative Effect of Irbesartan by Qiao Wang, Lingsen You, Zeyu Li, Leiyi Zhang, Xueqi Li, Xuesong Yang

    Published 2022-01-01
    “…The interindividual heterogeneity in response to the antihypertensive effect of irbesartan has received considerable attention because of gene polymorphism. In this study, we investigated the new combinational influences of AGTR1 and ABCB1 gene polymorphism on the therapeutic effect of irbesartan among Chinese hypertensive patients. …”
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    Suppressive Effect of Insulin on the Gene Expression and Plasma Concentrations of Mediators of Asthmatic Inflammation by Husam Ghanim, Kelly Green, Sanaa Abuaysheh, Manav Batra, Nitesh D. Kuhadiya, Reema Patel, Antoine Makdissi, Sandeep Dhindsa, Ajay Chaudhuri, Paresh Dandona

    Published 2015-01-01
    “…Insulin suppresses the expression of these genes and mediators related to asthma and may, therefore, have a potential role in the treatment of asthma.…”
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  10. 510

    Identification of Bacterial Lipopolysaccharide-Associated Genes and Molecular Subtypes in Autism Spectrum Disorder by He Y, He Y, Cheng B

    Published 2025-01-01
    “…A nomogram prediction model was developed based on these signatures, and we performed Gene Set Enrichment Analysis (GSEA), Gene Set Variation Analysis (GSVA), and immune cell infiltration analysis to assess the impact of BLI subtypes and their underlying mechanisms.Results: Our findings revealed 17 differentially expressed BLI genes in children with ASD, with BLNK, MAPK8, PRKCQ, and TNFSF12 identified as potential biomarkers. …”
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    Characterization of gene expression profiles in Alzheimer's disease and osteoarthritis: A bioinformatics study. by Nian Liu, Qian Deng, Zining Peng, Danning Mao, Yuanbo Huang, Fanyu Meng, Xiaoyu Zhang, Jiayan Shen, Zhaofu Li, Weitian Yan, Jiangyun Peng

    Published 2025-01-01
    “…In addition, the core genes were analyzed using gene set enrichment analysis and single-gene genome variation analysis.…”
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    Distribution of the arctic variant of the CPT1A gene in indigenous populations of Siberia by B. A. Malyarchuk, M. V. Derenko, G. A. Denisova, A. N. Litvinov

    Published 2016-12-01
    “…Population screening of the Arctic variant, which has arisen due to the G > A mutation at locus rs80356779 in the CPT1A gene, has been performed for the first time among indigenous peoples of Siberia (Chukchi, Koryaks, Evens, Evenks, Yakuts, Buryats and Altaians) and East Asia (Koreans). …”
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    The Identification and Validation of a Robust Immune-Associated Gene Signature in Cutaneous Melanoma by Le-Bin Song, Jiao-Chen Luan, Qi-Jie Zhang, Lin Chen, Hao-Yang Wang, Xue-Chen Cao, Ning-Hong Song, Yan Lu

    Published 2021-01-01
    “…In the multivariate Cox model, the gene signature was testified as a remarkable prognostic factor (HR=45.423, P<0.001). …”
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  19. 519

    Interferon-Stimulated Genes and Immune Metabolites as Broad-Spectrum Biomarkers for Viral Infections by Chien-Hsin Huang, Maudry Laurent-Rolle, Tyler L. Grove, Jack Chun-Chieh Hsu

    Published 2025-01-01
    “…The type I interferon (IFN-I) response is a critical component of the immune defense against various viral pathogens, triggering the expression of hundreds of interferon-stimulated genes (ISGs). These ISGs encode proteins with diverse antiviral functions, targeting various stages of viral replication and restricting infection spread. …”
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    Association Analysis of Reactive Oxygen Species-Hypertension Genes Discovered by Literature Mining by Ji Eun Lim, Kyung-Won Hong, Hyun-Seok Jin, Bermseok Oh

    Published 2012-12-01
    “…In this study, ROS-hypertension-related genes were collected by the biological literature-mining tools, such as SciMiner and gene2pubmed, in order to identify the genes that would cause hypertension through ROS. …”
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