Multinomial Regression with Elastic Net Penalty and Its Grouping Effect in Gene Selection by Liuyuan Chen, Jie Yang, Juntao Li, Xiaoyu Wang

“…By combining the multinomial likeliyhood loss and the multiclass elastic net penalty, the optimization model was constructed, which was proved to encourage a grouping effect in gene selection for multiclass classification.…”
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Reference Gene and Protein Expression Levels in Two Different NAFLD Mouse Models by Layanne C. C. Araujo, Silvana Bordin, Carla R. O. Carvalho

“…The expression levels of some reference genes and proteins are used for data normalization and quantification. …”
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The Ongoing Challenge of Hematopoietic Stem Cell-Based Gene Therapy for β-Thalassemia by Ekati Drakopoulou, Eleni Papanikolaou, Nicholas P. Anagnou

“…The major breakthrough in β-thalassemia gene therapy occurred a decade ago with the development of globin LVs. …”
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Comprehensive Bioinformatics Method to Explore Immune-Related Genes in the Pathogenesis of Myocardial Infarction by Xin Zhang, Yiren Yao, Ying Ding, Wenting Yan, Yang Gu, Xiwen Zhang, Xiaojin Xu

“…Objective: This study was aimed at exploring immune-related genes and their expression changes in myocardial infarction (MI) through comprehensive bioinformatics methods and validating these genes as potential diagnostic and therapeutic targets. …”
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Differential Gene Expression in Primary Breast Tumors Associated with Lymph Node Metastasis by Rachel E. Ellsworth, Lori A. Field, Brad Love, Jennifer L. Kane, Jeffrey A. Hooke, Craig D. Shriver

“…Primary breast tumors from women with negative (𝑛=41) and positive (𝑛=35) lymph node status matched for possible confounding factors were subjected to laser microdissection and gene expression data generated. Although ANOVA analysis (𝑃<.001, fold-change >1.5) revealed 13 differentially expressed genes, hierarchical clustering classified 90% of node-negative but only 66% of node-positive tumors correctly. …”
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The effect of sulfadiazine in manure on accumulation of sulfonamide resistance genes in freshly consumable plants by Leo van Overbeek, Björn Berendsen, Stefan Aanstoot, Alex Bossers, Els Nijhuis, Lina Russ, Beatriz Andreo Jimenez

Subjects: “…Sulfonamide resistance genes…”
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Aberrant Hepatic Methionine Metabolism and Gene Methylation in the Pathogenesis and Treatment of Alcoholic Steatohepatitis by Charles H. Halsted, Valentina Medici

“…The pathogenesis of alcoholic steatohepatitis (ASH) involves ethanol-induced aberrations in hepatic methionine metabolism that decrease levels of S-adenosylmethionine (SAM), a compound which regulates the synthesis of the antioxidant glutathione and is the principal methyl donor in the epigenetic regulation of genes relevant to liver injury. The present paper describes the effects of ethanol on the hepatic methionine cycle, followed by evidence for the central role of reduced SAM in the pathogenesis of ASH according to clinical data and experiments in ethanol-fed animals and in cell models. …”
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Modulation of first-passage time for bursty gene expression via random signals by Qiuying Li, Lifang Huang, Jianshe Yu

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Combined Parental Thrombophilia Gene Mutation Defects in Couples with Repeated Pregnancy Loss by Mehdi Kashifard, Zahra Basirat, Fatemeh Ramezani, Faeze Ghofrani, Masoumeh Golsorkhtabaramiri

“…Aims: In this study, the prevalence of some combined parental thrombophilia gene mutation defects was studied in couples with RPL. …”
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A Primer for Disease Gene Prioritization Using Next-Generation Sequencing Data by Shuoguo Wang, Jinchuan Xing

Subjects: “…disease gene prioritization…”
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A multi-trait approach identified 7 novel genes for back pain by Nadezhda M. Belonogova, Elizaveta E. Elgaeva, Irina V. Zorkoltseva, Anatoliy V. Kirichenko, Gulnara R. Svishcheva, Maxim B. Freidin, Frances M. K. Williams, Pradeep Suri, Tatiana I. Axenovich, Yakov A. Tsepilov

“…We applied a powerful multi-trait and gene-based approach to association analysis of BP to identify novel genes associated with BP. …”
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Publication of a Special Issue: Gene Dosage Effect During Embryonic Development by Claire Redhead

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Neuroimmunology of psoriasis: Possible roles for calcitonin gene-related peptide in its pathogenesis by Joshua Kotlyar, Richard D. Granstein

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Identification and Functional Analysis of PANoptosis‐Associated Genes in the Progression From Sepsis to ARDS by Zhong‐Hua Lu, Yan Tang, Hu Chen, Feng Liu, Mei Liu, Lu Fu, Xian‐Kai Wang, Ming‐Juan Li, Wei‐Li Yu, Yun Sun

“…This study aims to elucidate the PANoptosis‐related genes (PRGs) and their involvement in the progression of sepsis to ARDS. …”
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Multiomics identify the gene expression signature of the spinal cord during aging process by Lintao Xu, Jingyu Wang, Jinjie Zhong, Weiwei Lin, Gerong Shen, Ning He, Xingjia Mao, Chunyan Fu, Zhaobo Huang, Fengdong Zhao, Xin Ye, Yongjian Zhu, Mingzhi Zheng, Hui Li, Lin-lin Wang, Kai Zhong, Lijun Zhu, Ying-ying Chen

“…Bulk RNA sequencing reveals that 526 genes are upregulated and 300 genes are downregulated in senescent spinal cords. …”
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Proposal of a new nomenclature for introns in protein-coding genes in fungal mitogenomes by Shu Zhang, Yong-Jie Zhang

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Expression of Tropomyosin 1 Gene Isoforms in Human Breast Cancer Cell Lines by Syamalima Dube, Santhi Yalamanchili, Joseph Lachant, Lynn Abbott, Patricia Benz, Charles Mitschow, Dipak K. Dube, Bernard J. Poiesz

“…Four novel human TPM1 gene RNA isoforms were discovered (λ, μ, ν, and ξ), which were not identified in adult and fetal human cardiac tissues. …”
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Analysis of QTLs Associated with the Rice Quality Related Gene by Double Haploid Populations by Gyu-Ho Lee, Byung-Wook Yun, Kyung-Min Kim

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Interactions between ABC gene polymorphisms and processing speed in predicting depression severity by Meijiang Jin, Lei Ji, Maojia Ran, Yan Bi, Hang Zhang, Yuanmei Tao, Hanmei Xu, Shoukang Zou, Hong Zhang, Tao Yu, Li Yin

“…Therefore, this study aimed to investigate whether ABC family genes are associated with cognitive function, and the combined effects of genes and cognitive function on the severity of depression. …”
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Prognostic values of intracellular cell-related genes in esophageal cancer and their regulatory mechanisms by Wei Cao, Dacheng Jin, Weirun Min, Haochi Li, Rong Wang, Jinlong Zhang, Yunjiu Gou

“…Differentially expressed genes (DEGs) in ESCA samples were identified, with those related to intercellular structures designated cell-in-cell-related differential expression genes (CIC-related DEGs). …”
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