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441
Identification and Analysis of Key Immune- and Inflammation-Related Genes in Idiopathic Pulmonary Fibrosis
Published 2025-02-01“…Two machine learning algorithms were used to further screen key genes. Genes with an area under curve (AUC) of > 0.7 in receiver operating characteristic (ROC) curves, significant expression and consistent trends across datasets were considered key genes. …”
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442
Sideroflexin family genes were dysregulated and associated with tumor progression in prostate cancers
Published 2025-02-01Subjects: Get full text
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443
FusionScan: accurate prediction of fusion genes from RNA-Seq data
Published 2019-07-01Subjects: Get full text
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444
Identification of Differentially Expressed Genes in Pituitary Adenomas by Integrating Analysis of Microarray Data
Published 2015-01-01“…Pituitary adenomas, monoclonal in origin, are the most common intracranial neoplasms. Altered gene expression as well as somatic mutations is detected frequently in pituitary adenomas. …”
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445
Gene therapy by hepatocyte growth factor results in regression of experimental liver fibrosis
Published 2010-08-01“…Obtained results allow to consider gene therapy by hepatocyte growth factor in composition of non-viral vectors as one of perspective methods of treatment of chronic liver diseases.…”
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446
Distribution and environmental dissemination of antibiotic resistance genes in poultry farms and surrounding ecosystems
Published 2025-01-01Subjects: Get full text
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447
NMD Microarray Analysis for Rapid Genome-Wide Screen of Mutated Genes in Cancer
Published 2005-01-01“…Finding genes undergoing mutations is challenging and slow, even in the post-genomic era. …”
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448
The BnaBPs gene regulates flowering time and leaf angle in Brassica napus
Published 2024-10-01“…We cloned two homologous BP genes, BnaBPA03 and BnaBPC03, from B. napus Xiaoyun. …”
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449
Polymorphism of the mannose-binding lectin gene in the Arctic indigenous populations of the Russian Federation
Published 2020-12-01Subjects: Get full text
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450
Correlation of Dynamic PET and Gene Array Data in Patients with Gastrointestinal Stromal Tumors
Published 2012-01-01“…The results obtained with dynamic PET (dPET) were compared to gene expression data obtained in patients with gastrointestinal stromal tumors (GIST). …”
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451
Low dose deltamethrin exposure affects gene expression in rat frontal cortex
Published 2025-02-01“…Our study investigates the impact of oral exposure to deltamethrin, a widely used Type II pyrethroid pesticide, on gene expression in the frontal cortex of rats. We used differential gene expression data from frontal cortex dissections from male Long-Evans rats exposed to a 3 mg/kg oral dose of deltamethrin (or vehicle) to perform a 3Pod analysis in R Studio, which included GSEA, Enrichr, and iLINCS analyses. …”
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452
Worldwide gene pool of fiber flax at VIR, and breeding of rust-resistant varieties
Published 2020-06-01Subjects: Get full text
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453
An In silico Approach towards Finding the Cancer-Causing Mutations in Human MET Gene
Published 2023-01-01“…The impact of mutations occurring in the MET gene is demonstrated by their detrimental effects on normal cellular functions. …”
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454
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455
Gene Polymorphisms and Susceptibility to Functional Dyspepsia: A Systematic Review and Meta-Analysis
Published 2019-01-01“…An additive model was adopted to determine whether previous studied genes are associated with FD susceptibility. Carriers of minor allele in GNB3 825C>T (OR=1.15, 95% CI 0.99-1.34, P=0.07), SCL6A4 5HTTLPR (OR=0.92, 95% CI 0.75-1.12, P=0.40), and CCK-1R 779T>C (OR=0.86, 95% CI 0.72-1.03, P=0.09) genes failed to demonstrate susceptibility to FD. …”
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456
Oct4 Gene Expression in Primary Colorectal Cancer Promotes Liver Metastasis
Published 2019-01-01“…Purpose. The Oct4 gene plays an important role in undifferentiated embryonic stem cells and regulates stem cell pluripotency. …”
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457
Expression of the Autoimmune Regulator Gene and Its Relevance to the Mechanisms of Central and Peripheral Tolerance
Published 2012-01-01“…The autoimmune polyendocrine syndrome type 1 (APS-1) is a monogenic disease due to pathogenic variants occurring in the autoimmune regulator (AIRE) gene. Its related protein, AIRE, activates the transcription of genes encoding for tissue-specific antigens (TsAgs) in a subset of medullary thymic epithelial cells: the presentation of TsAgs to the maturating thymocytes induces the apoptosis of the autoreactive clones and constitutes the main form of central tolerance. …”
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458
Synthetic Gene Drives in Plants: Development Strategies, Potential Applications, and Ethical Considerations
Published 2024-12-01“…Additionally, we discuss the biosafety concerns related to gene drive experiments and field releases, strategies to counteract unwanted gene drives, and the ethical implications, particularly considering the risk of the intentional misuse of gene drive technology and the need for robust regulatory and monitoring frameworks.…”
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459
Associations of CTLA4 Gene Polymorphisms with Graves’ Ophthalmopathy: A Meta-Analysis
Published 2014-01-01“…Our results showed that the SNP49 polymorphism of CTLA4 gene was related to increased risk of GO.…”
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460
Identification of Key Genes and Pathways Involved in Circulating Tumor Cells in Colorectal Cancer
Published 2022-01-01“…For identification of key genes and pathways, GSE31023, contained CTCs from six metastatic CRC patients and three controls, was retrieved for differentially expressed gene (DEG) analysis. …”
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