Infectious bursal disease virus: identification of the novel genetic group and reassortant viruses by L. O. Scherbakova, Ye. V. Ovchinnikova, T. N. Zybina, S. N. Kolosov, N. G. Zinyakov, Z. B. Nikonova, D. B. Andreychuk, I. A. Chvala

“…This is related to the fact that the virulence is determined not only based on the characteristics of the VP2 gene (A segment) but on the characteristics of the VP1 gene (B segment) as well. …”
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Comprehensive analysis of 111 Pleuronectiformes mitochondrial genomes: insights into structure, conservation, variation and evolution by Suxu Tan, Wenwen Wang, Jinjiang Li, Zhenxia Sha

“…Results Our analysis revealed a conserved gene content of protein-coding genes and rRNA genes, but varying numbers of tRNA genes and control regions across species. …”
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Creation of transgenic mice susceptible to coronaviruses: a platform for studying viral pathogenesis and testing vaccines by N. R. Battulin, O. L. Serov

“…In addition, the use of the technology of targeted genome modification using CRISPR/Cas9 made it possible to create lines of transgenic animals with the insertion of the human ACE2 gene under the control of the endogenous murine Ace2 gene promoter. …”
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Virulence Genotyping of Pasteurella multocida Isolated from Multiple Hosts from India by Laxmi Narayan Sarangi, Adyasha Priyadarshini, Santosh Kumar, Prasad Thomas, Santosh Kumar Gupta, Viswas Konasagara Nagaleekar, Vijendra Pal Singh

“…With the exception of toxA gene, all other virulence associated genes were found to be regularly distributed among host species. …”
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Heterologous Ectoine Production in Escherichia coli: Optimization Using Response Surface Methodology by I Putu Parwata, Deana Wahyuningrum, Sony Suhandono, Rukman Hertadi

“…The recombinant E. coli successfully expressed the ectoine gene cluster of Halomonas elongata BK-AG25 under the control of the T7 promoter. …”
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IL1RN and PRRX1 as a Prognostic Biomarker Correlated with Immune Infiltrates in Colorectal Cancer: Evidence from Bioinformatic Analysis by Qi Wang, Xufeng Huang, Shujing Zhou, Yuntao Ding, Huizhi Wang, Weiye Jiang, Min Xu

“…For this, we identified 704 differentially expressed genes (DEGs) by intersecting three datasets, GSE41328, GSE37364, and GSE15960 from Gene Expression Omnibus database, to maximize the accuracy of the results. …”
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Multigene Panel Testing in Turkish Hereditary Cancer Syndrome Patients by Esra ARSLAN ATES, Ayberk TURKYILMAZ, Ceren ALAVANDA, Ozlem YILDIRIM, Ahmet Ilter GUNEY

“…Objective: Hereditary cancer syndromes (HCSs) are a heterogenous group of disorders caused by germline pathogenic variations in various genes that function in cell growth and proliferation. …”
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Occurrence, Antimicrobial Resistance, and Virulence Profiles of Salmonella Serovars Isolated from Wild Reptiles in South Africa by Lungile N. Mlangeni, Tsepo Ramatla, Kgaugelo E. Lekota, Cormac Price, Oriel Thekisoe, Che Weldon

“…The isolates were identified using polymerase chain reaction (PCR) by amplifying the invA gene and were further confirmed by 16S rRNA gene sequencing. …”
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Pengaruh Pemberian Mesenchymal Stem Cells Wharton's Jelly terhadap Ekspresi Gen Sirtuin 1 pada Tikus Model Alzheimer by Havina Nurul Aizah, Amel Yanis, Hirowati Ali, Tofrizal Tofrizal, Cimi Ilmiawati, Dessy Arisanty

“…Objective: To observe the Sirtuin-1 gene in Alzheimer's disease rat models that AlCl3 was inducing after being given MSC-WJ. …”
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Analysis of the circadian rhythm of biological processes in mouse liver and kidney by I. N. Podkolodnyy, N. N. Tverdokhleb, O. A. Podkolodnaya

“…Genes with a pronounced daily dynamics of translation were revealed (3 358 genes in the liver and 2 938 in the kidneys). …”
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Novel Treatment of Small-Cell Neuroendocrine of the Vagina by Kathryn Kostamo, Mishka Peart, Nathalie McKenzie, Conisha Holloman, S. J. Carlan, Li Ge, John Maksem

“…Eighty-five percent of patients die within one year of diagnosis from metastatic disease despite multimodal therapy. Gene expression profiling of tumor tissue may be useful for treatment options for various malignancies. …”
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ANALYSIS OF THE INTERACTION OF LIPID METABOLISM ALLELES IN DYSLIPIDEMIA by I. V. Nikolaev, R. V. Mulyukova, L. R. Kayumova, E. V. Vorobievа, V. Yu. Gorbunova

“…Associations of certain SNPs (G-2548A in the promoter region of the leptin gene (LEP), A223G in exon 4 of the leptin receptor gene (LEPR), T495G in intron 8 in the lipoprotein lipase gene (LPL), and C34G in exon 8 of a nuclear receptor (PPARG)) with disturbed lipid metabolism have been investigated, and their cumulative contribution to the development of dyslipidemia is demonstrated.…”
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Novel Genetic Findings in a Chinese Family with Axenfeld-Rieger Syndrome by Kuanshu Li, Liu Yang, Ying Liu, Ding Lin

“…Conclusions. We found novel gene mutations in a Chinese family with ARS, which provides us with a better understanding of the gene mutation spectrum of ARS and the assistance for the genetic counseling and gene-specific therapy in the future.…”
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Human-Specific Endogenous Retroviruses by Anton Buzdin

“…A total of 134 potential promoters and enhancers have been added to the human DNA, about 50% of them in the close gene vicinity and 22% in gene introns. For 60 such human-specific promoters, their activity was confirmed by in vivo assays, with the transcriptional level varying ~1000-fold from hardly detectable to as high as ~3% of β-actin transcript level. …”
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The Domestic Cat as a Large Animal Model for Characterization of Disease and Therapeutic Intervention in Hereditary Retinal Blindness by Kristina Narfström, Koren Holland Deckman, Marilyn Menotti-Raymond

“…The first model is the autosomal recessive, slowly progressive, late-onset, rod-cone degenerative disease caused by a mutation in the CEP290 gene. The second model addressed in this paper is the autosomal dominant early onset rod cone dysplasia, putatively caused by the mutation found in the CRX gene. …”
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Pseudomonas Aeruginosa and Cystic Fibrosis: Antibiotic Therapy and the Science behind the Magic by Noni E MacDonald

“…Research that stemmed from the discovery of the CF gene has shed new light on the inter-relationship of these microbes and the respiratory epithelial lung changes secondary to the CF gene. …”
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The Challenges and Opportunities in the Clinical Application of Noncoding RNAs: The Road Map for miRNAs and piRNAs in Cancer Diagnostics and Prognostics by Preethi Krishnan, Sambasivarao Damaraju

“…These RNAs perform diverse functions—gene regulation, splicing, translation, and posttranscriptional modifications. …”
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Successful Pallidal Deep Brain Stimulation Treatment in a Case of Generalized Dystonia due to a Novel ANO3 Mutation by Lizl Lasky, Lindsay Bliss, Christos Sidiropoulos

“…Dystonia is a ubiquitous syndrome, with a growing number of genes being continually identified. Mutations in the anoctamin-3 gene have been described to cause dystonia but the management and long-term outcomes are still largely unknown. …”
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miR-212 Promotes Cardiomyocyte Hypertrophy through Regulating Transcription Factor 7 Like 2 by Jinxia Yuan, Guoliang Yuan

“…In addition, miR-212 targets TCF7L2 and inhibits the expression of this gene. miRNA-212 targets TCF7L2 and inhibits the expression of this gene, possibly through this pathway to promote cardiomyocyte hypertrophy.…”
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Research Status of Clustered Regulary Interspaced Short Palindromic Repeats Technology in the Treatment of Human Papillomavirus (HPV) Infection Related Diseases by Minxue Tang MD

“…This approach offers a refined methodology for the rapid detection of viral infections and provides a robust platform for the safe and effective treatment of diseases associated with viral infections through gene therapy. Purpose: Gene therapy, within this context, involves the strategic delivery of genetic material into target cells via a vector. …”
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