Differential Impact of Stress Reduction Programs upon Ambulatory Blood Pressure among African American Adolescents: Influences of Endothelin-1 Gene and Chronic Stress Exposure by Mathew J. Gregoski, Vernon A. Barnes, Martha S. Tingen, Yanbin Dong, Haidong Zhu, Frank A. Treiber

“…Stress-activated gene × environment interactions may contribute to individual variability in blood pressure reductions from behavioral interventions. …”
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Clinical characteristics of and growth hormone treatment effects on short stature with type 1 insulin-like growth factor receptor (IGF1R) gene alteration by Yuki Kawashima-Sonoyama, Keisuke Wada, Kei Yamamoto, Masanobu Fujimoto, Noriyuki Namba, Takeshi Taketani

“…Short stature with IGF-1 receptor (IGF1R) gene alteration is known as small-for-gestational-age (SGA) short stature with elevated serum IGF1 levels. …”
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Identification and Characterization of the <i>ROP GTPase</i> Gene Family in Strawberry and the Positive Role of <i>FveROP4</i> in Fruit Resistance to Gray Mold by Shuai Zhao, Baode Zhu, Zhijun Zou, Yushan Zhai, Sufeng Liao, Ming Xu, Kunyang Li, Nasir Mehmood, Xiong Liao

“…In this study, we identified 53 <i>ROP</i> genes across the genomes of six Rosaceae species. …”
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Single dose of recombinant baculovirus vaccine expressing sigma B and sigma C genes provides good protection against novel duck reovirus challenge in ducks by Yufei Wang, Siyi Xu, Xia Chen, Yunlong Dou, Xingzhu Yang, Zenglei Hu, Shuang Wu, Xiaoquan Wang, Jiao Hu, Xiufan Liu

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Glucocorticoid receptor gene (NR3C1) methylation, childhood maltreatment, multilevel reward responsiveness and depressive and anxiety symptoms: A neuroimaging epigenetic study by Yajing Xu, Shan Yang, Cong Cao

“…We conducted the first longitudinal study to investigate the extent to which DNA methylation of a stress-related gene—NR3C1—interacts with childhood maltreatment in association with young adult reward responsiveness (RR) and the downstream risk of depressive (anhedonia dimension in particular) and anxiety symptoms. …”
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Intricate interplay of CRISPR-Cas systems, anti-CRISPR proteins, and antimicrobial resistance genes in a globally successful multi-drug resistant Klebsiella pneumoniae clone by Jianping Jiang, Astrid V. Cienfuegos-Galletd, Tengfei Long, Gisele Peirano, Tingyu Chu, Johann D. D. Pitout, Barry N. Kreiswirth, Liang Chen

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A Comparative Transcriptome Analysis Reveals the Effects of Letrozole and 17α-Methyltestosterone on the Expression of Reproductive-Related Genes in Golden Pompano (<i>Trachinotus ovatus</i>) by Qi Zhou, Yan Wang, Yuwen Guo, Guangli Li, Tao Wang, Huapu Chen

“…Following LZ treatment, the transcriptome data identified 156, 890, and 1286 different expression genes (DEGs) in the hypothalamus, the liver, and the gonad, respectively. …”
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Screening of potential GCMS derived antimigraine compound from the leaves of Abrus precatorius Linn to target “calcitonin gene related peptide” receptor using in silico analysis by Parthasarathy V., Ajay Kumar T.V

“…Calcitonin receptor-like receptor (CRLR) is a human protein, that produces a calcitonin gene-related peptide receptor (CGRP) when associates with human receptor activity-modifying protein-1 (HRAMP1). …”
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Computational analysis of spliced leader trans-splicing in the regenerative flatworm <i>Macrostomum lignano</i> reveals its prevalence in conserved and stem cell related genes by K. V. Ustyantsev, E. V. Berezikov

“…Finally, we found that a majority of SL trans-spliced genes are evolutionarily conserved and signif icantly over-represented in neoblast-specific genes. …”
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Molecular Study of Acinetobacter baumannii Isolates for Metallo-β-Lactamases and Extended-Spectrum-β-Lactamases Genes in Intensive Care Unit, Mansoura University Hospital, Egypt by Nashwa M. Alkasaby, Maysaa El Sayed Zaki

“…MBLs genes were positive in 266 isolates (95%) and ESBLs genes were positive in 8 isolates (2.9%). …”
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Clinical Specimens are the Pool of Multidrug- resistant Pseudomonas aeruginosa Harbouring oprL and toxA Virulence Genes: Findings from a Tertiary Hospital of Nepal by Yamuna Chand, Sujan Khadka, Sanjeep Sapkota, Suprina Sharma, Santosh Khanal, Alina Thapa, Binod Rayamajhee, Dhruba Kumar Khadka, Om Prakash Panta, Dipendra Shrestha, Pramod Poudel

“…The multidrug- or extensively drug-resistant (MDR/XDR) Pseudomonas aeruginosa carrying some virulence genes has become a global public health threat. However, in Nepal, there is no existing report showing the prevalence of oprL and toxA virulence genes among the clinical isolates of P. aeruginosa. …”
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Discovery of mutated oncodriver genes associated with glioblastoma originated from stem cells of subventricular zone through whole exome sequence profile analysis, and drug repurposing by Arnob Sarker, Burhan Uddin, Reaz Ahmmed, Sabkat Mahmud, Alvira Ajadee, Md. Al Amin Pappu, Md. Abdul Aziz, Md. Nurul Haque Mollah

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Association of β-Catenin, APC, SMAD3/4, Tp53, and Cyclin D1 Genes in Colorectal Cancer: A Systematic Review and Meta-Analysis by Hongfeng Yan, Fuquan Jiang, Jianwu Yang

“…Accumulating evidence indicates that the expression and/or variants of several genes play an essential role in the progress of colorectal cancer (CRC). …”
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5,10-methylenetetrahydrofolate reductase C677T gene polymorphism as a risk factor for premature coronary artery disease in patients with type 2 diabetes mellitus by Nisreen O. Mohammed, Ibtisam A. Ali, Bahaelddin K. Elamin, Bakri Osman Saeed

“…Homocysteine levels showed a significant association with CAD, p&lt;0.001, OR 3.2, 95% CI (1.9—5.5).ConclusionsOur study suggests that C677T polymorphism of MTHFR gene and hyperhomocysteinemia are risk factors for PCAD in Sudanese population with T2DM.…”
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Efficient Acquisition of Fully Human Antibody Genes against Self-Proteins by Sorting Single B Cells Stimulated with Vaccines Based on Nitrated T Helper Cell Epitopes by Liangliang Jiang, Tao Jiang, Jianhua Luo, Yanliang Kang, Yue Tong, Xiaoda Song, Xiangdong Gao, Wenbing Yao, Hong Tian

“…The analysis of antibody genes showed that sorted B cells underwent the extensive somatic mutation of the antibody genes. …”
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Systematic analysis of co-expression network and gene expression profile of differentially expressed lncRNA-mRNA one week after spinal cord injury by Yi Kang, Yijie Song, Zhongju Shi, Qiang Li, Yigang Lv, Mengfan Hou, Cui Ding, Jing Xie, Yongfu Lou, Chi Zhang, Huan Jian, Xueying Li, Hengxing Zhou, Shiqing Feng

“…Abbreviations: SCI: spinal cord injury; CNS: central nervous system; YLDs: years of life lived with disability; lncRNAs: long noncoding RNAs; mRNAs: messenger RNAs; DE: differentially expressed; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; GSEA: gene set enrichment analysis; RIN: Renewable Identification Number; PCA: principal component analysis; PPI: protein–protein interaction; MF, molecular function; BP: biological process; CC: cellular component; MCODE: molecular complex detection…”
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Polymorphic Single‐Nucleotide Variants in miRNA Genes and the Susceptibility to Colorectal Cancer: Combined Evaluation by Pairwise and Network Meta‐Analysis, Thakkinstian's Algorithm and FPRP Criterium by Qing Liu, Ivan Archilla, Sandra Lopez‐Prades, Ferran Torres, Jordi Camps, Miriam Cuatrecasas

“…ABSTRACT Background Considerable epidemiological studies have examined the correlation between polymorphic single‐nucleotide variants (SNPs) in miRNA genes and colorectal carcinoma (CRC) risk, yielding inconsistent results. …”
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An induced pluripotent stem cell line, NIMHi014-A, generated from PBMCs of an epileptic patient harbouring a variant of the SCN1A gene by Madhura Milind Nimonkar, Gautham Arunachal, Ananthapadmanabha Kotambail, Ramya Sukrutha, Kenchaiah Raghavendra, Ghati K Chetan, Bhupesh Mehta, Yogananda S. Markandeya

“…The proband harbours a de novo, pathogenic variant of the SCN1A gene, which encodes the NaV1.1 subtype of the voltage gated sodium channel. …”
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The Polymorphism of the ACE Gene Affects Left Ventricular Hypertrophy and Causes Disturbances in Left Ventricular Systolic/Diastolic Function in Patients with Autosomal Dominant Polycystic Kidney Disease by Maria Wanic-Kossowska, Bartlomiej Posnik, Mikolaj Kobelski, Elzbieta Pawliczak, Krzysztof Pawlaczyk, Krzysztof Hoppe, Krzysztof Schwermer, Dorota Sikorska

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Dim blue light at night worsens high-fat diet-induced kidney damage via increasing corticosterone levels and modulating the expression of circadian clock genes by Wenji Ren, Zixu Wang, Yulan Dong, Jing Cao, Ting Gao, Qingyun Guo, Yaoxing Chen

“…We were surprised to find that dBL altered the expression of the circadian clock genes, resulting in a decrease in the positively regulated genes Bmal1, Clock, and an increase in the negatively regulated genes Per1, Per2, Per3. …”
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