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Comparative analysis of galectin-1, galectin-3, and galectin-8 signatures in normal and choriocarcinoma trophoblast cell lines
Published 2024-01-01Subjects: “…galectin-1…”
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Editorial: Galectins and hormones in health and disease
Published 2025-02-01Subjects: “…galectin…”
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The Role of Galectins as Modulators of Metabolism and Inflammation
Published 2018-01-01“…Galectins are β-galcotosid-binding lectins. The function of galectins varies with their tissue-specific and subcellular location, and their binding to carbohydrates makes them key players in several intra- and extracellular processes where they bind to glycosylated proteins and lipids. …”
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Galectin-3 Is a Potential Mediator for Atherosclerosis
Published 2020-01-01“…Numerous studies have implicated inflammation as a key player in the initiation and progression of atherosclerosis. Galectin-3 (Gal-3) is a 30 kDa β-galactose, highly conserved and widely distributed intracellularly and extracellularly. …”
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Galectin-1 as an Emerging Mediator of Cardiovascular Inflammation: Mechanisms and Therapeutic Opportunities
Published 2018-01-01“…Galectin-1 (Gal-1), an evolutionarily conserved β-galactoside-binding lectin, controls immune cell homeostasis and tempers acute and chronic inflammation by blunting proinflammatory cytokine synthesis, engaging T-cell apoptotic programs, promoting expansion of T regulatory (Treg) cells, and deactivating antigen-presenting cells. …”
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Mouse Thyroid Gland Changes in Aging: Implication of Galectin-3 and Sphingomyelinase
Published 2017-01-01“…A possible relationship between galectin-3, neutral sphingomyelinase, and aging has been discussed.…”
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mGBP2 engages Galectin-9 for immunity against Toxoplasma gondii.
Published 2025-01-01“…Here, to unravel mGBP2 functions, we report Galectin-9 (Gal9) as a critical mGBP2 interaction partner engaged for immunity to T. gondii. …”
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Serum Galectin-3 Predicts Mortality in Venoarterial Extracorporeal Membrane Oxygenation Patients
Published 2023-01-01“…We investigated the potential use of galectin-3 (Gal-3) as a prognostic indicator for patients with cardiogenic shock and developed a predictive mortality model for venoarterial extracorporeal membrane oxygenation (VA-ECMO). …”
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Plasma galectin-3 is associated with decreased glomerular filtration rate in chronic HIV
Published 2023-12-01“…We evaluated plasma galectin-3 (Gal-3), a circulating marker of fibrosis, and its association with renal function. …”
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IL-17 Is a Key Regulator of Mucin-Galectin-3 Interactions in Asthma
Published 2021-01-01“…We previously showed that the absence of tissue inhibitor of metalloproteinase 1 (TIMP-1) enhances lung inflammation, airway hyperreactivity, and lung remodeling in asthma in an ovalbumin (OVA) asthma model of TIMP-1 knockout (TIMPKO) mice as compared to wild-type (WT) controls and mediated by increased galectin-3 (Gal-3) levels. Additionally, we have shown that in the lung epithelial cell line A549, Gal-3 inhibition increases interleukin-17 (IL-17) levels, leading to increased mucin expression in the airway epithelium. …”
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Galectin-3: A Novel Marker for the Prediction of Stroke Incidence and Clinical Prognosis
Published 2022-01-01“…Among these proteins, a few studies investigated mainly the roles played by galectin-1 (Gal-1) and galectin-3 (Gal-3) in the molecular mechanisms of atherosclerosis and in brain tissue remodeling after a stroke event. …”
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Galectins as New Prognostic Markers and Potential Therapeutic Targets for Advanced Prostate Cancers
Published 2013-01-01“…This review both discusses whether the “galectin-signature” might serve as a reliable biomarker for the identification of patients with high risk of metastasis and assesses the galectin-glycan lattices as potential novel targets for anticancer therapies. …”
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Galectin-3 secreted by triple-negative breast cancer cells regulates T cell function
Published 2025-02-01Subjects: Get full text
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Anti-inflammatory Property of Galectin-1 in a Murine Model of Allergic Airway Inflammation
Published 2019-01-01“…Galectin-1 (Gal-1) has immunomodulatory activities in various allergic inflammatory disorders, but its potential anti-inflammatory properties on allergic airway diseases have not been confirmed. …”
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Galectin-10 Is Released in the Nasal Lavage Fluid of Patients with Aspirin-Sensitive Respiratory Disease
Published 2012-01-01“…Galectin-10 was evaluated in tissue of nasal polyps by western blot. …”
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Galectin-3 Inhibitors Suppress Anoikis Resistance and Invasive Capacity in Thyroid Cancer Cells
Published 2021-01-01“…Accumulating evidence suggests that galectin-3 is a histologic marker of thyroid cancer. …”
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Metformin dosage and galectin-3 levels: insights from PCOS patients preparing for IVF
Published 2025-01-01Subjects: Get full text
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Circulating Galectin-3 and Atrial Fibrillation Recurrence after Catheter Ablation: A Meta-Analysis
Published 2019-01-01“…Background. Galectin-3 (Gal-3) is involved in fibrosis and heart failure. …”
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Correlation between Galectin-3 and Adverse Outcomes in Myocardial Infarction Patients: A Meta-Analysis
Published 2020-01-01“…Trials included using galectin-3 to estimate prognosis in myocardial infarction (MI) patients. …”
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Circulating Galectin-3 and Aldosterone for Predicting Atrial Fibrillation Recurrence after Radiofrequency Catheter Ablation
Published 2022-01-01“…Background. Circulating galectin-3 (Gal-3) and aldosterone (ALD) are involved in fibrosis and inflammation. …”
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