The association between TyG index and cardiovascular mortality is modified by antidiabetic or lipid-lowering agent: a prospective cohort study by Changchang Fang, Nanqin Peng, Jiang Cheng, Xiyu Zhang, Wenli Gu, Zicheng Zhu, Xiaoping Yin, Zhiwei Yan, Jing Zhang, Peng Yu, Xiao Liu

“…These findings suggest that future studies on the TyG index and its relationship with CVD and mortality should account for the modifying effects of these agents. …”
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Smartphone apps for mental health: systematic review of the literature and five recommendations for clinical translation by Aljawharah Almuqrin, Ryan Hammoud, Ilham Terbagou, Stefania Tognin, Andrea Mechelli

“…This review proposes five recommendations for improving clinical translation in future studies.…”
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Fingerprinting of ruby and sapphire gemstones through Fourier-transform infrared (FTIR) methodologies by A. Soares de Sousa, E. M. C. Gomes, L. Bayés-García, A. Di Mariano, M. Garcia-Valles

“…These spectral fingerprints can be used to distinguish between natural, synthetic, and treated rubies and sapphires and contribute to existing databases, allowing for simpler and faster gemological analysis in future studies.</p>…”
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How defensive medicine is defined in European medical literature: a systematic review by Nathalie Baungaard, Elisabeth Assing Hvidt, Helle Gerbild, Merethe Kirstine Andersen, Jesper Lykkegaard, Pia Ladeby Skovvang

“…In order to compare results pertaining to defensive medicine across countries, future studies are recommended to specify whether they are using the narrow or broad definition of defensive medicine.PROSPERO registration number CRD42020167215.…”
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Evaluation of Treatment Patterns and Maintenance Dose Titration Among Patients With Crohn’s Disease Initiating Biologics With 3 Years of Follow-Up by Ruizhi Zhao, Zhijie Ding, Parul Gupta, Laurence Gozalo, Robert Bruette, Victor M. Johnson, Keshia Maughn, Yihang Liu, Sumesh Kachroo

“…**Conclusions:** Patients with CD on UST had the highest persistence and lowest dose escalation across different biologic users over the 3-year follow-up period, possibly suggesting a better clinical response of UST. Future studies with longer follow-up adjusting for confounders are needed to better understand treatment patterns among biologics users.…”
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The Effects of Soft Tissue Flossing on Hamstring Range of Motion and Lower Extremity Power by Zachary Maust, Debbie Bradney, Sean M Collins, Caroline Wesley, Thomas G Bowman

“…Flossing could be beneficial when treatment or performance preparation goals are increased flexibility without decreased power. Future studies should continue to examine the clinical effectiveness of flossing on an injured population.…”
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3D-augmentation of 2D ultrasound for appendicitis diagnosis: A cross-sectional pilot study by Rebecca G. Theophanous, Elias Jaffa, Matthew R. Morgan, Carl D. Herickhoff, Erica Peethumnongsin, Joao Ricardo Nickenig Vissoci, Joshua S. Broder

“…We presented 3DUS images of acute appendicitis comparable to 2DUS and CT as visual demonstrations of feasibility. Future studies with larger cohorts are needed to assess diagnostic accuracy.…”
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Mt or not Mt: Temporal variation in detection probability in spatial capture-recapture and occupancy models by Sollmann, Rahel

“…There are cases where we cannot or may not want to ignore temporal variation in detection: a behavioral response to detection and certain SCR observation models do not allow collapsing data across sampling occasions; and temporal variation in detection may be informative of species phenology/behavior or for future study planning. But this study shows that it can be safely ignored under a range of conditions when analyzing SCR or occupancy data. …”
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Combined analysis of 16S rRNA gene sequencing data reveals core vaginal bacteria across livestock species by Lucille C. Jonas, Lucille C. Jonas, Curtis R. Youngs, Stephan Schmitz-Esser, Stephan Schmitz-Esser

“…A better understanding of the livestock vaginal microbiota is required for future studies aimed at elucidation of the functional significance of individual microbes with respect to livestock reproductive efficiency. …”
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Reliability of an Observational Biomechanical Analysis Tool in Adolescent Baseball Pitchers by Steven F DeFroda, Dai Sugimoto, Steven J Staffa, Donald S Bae, Ellen Shanley, Charles A Thigpen, Peter K Kriz

“… # Conclusions The 20-item ACES scoring tool with 2D video analysis demonstrated excellent intra- and interrater reliability when utilized by raters of different musculoskeletal disciplines. Future studies validating 2D vs. 3D methodology are warranted before ACES is widely disseminated and utilized for adolescent pitchers. …”
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Accuracy of Lung Ultrasonography for Diagnosis of Heart Failure; a Systematic Review and Meta-analysis by Erfan Rahmani, Masoud Farrokhi, Mehrdad Farrokhi, Shadi Nouri, Atousa Moghadam Fard, Behnam Hoorshad, Ramin Atighi, Erfan Ghadirzadeh, Michael Tajik, Habibollah Afshang, Aida Naseri, Mohadeseh Asoudehfard, Shiva Samami Kojidi, Arsham Ebnemehdi, Mehdi Rezaei, Maziar Daneshvar, Amirali Makhmalbaf, Sepideh Hassanpour Khodaei, Shirin Farsi, Saber Barazandeh Rad, Fateme Nozari, Pouya Rezaei, Negar Babapour, Salman Delavar, Babak Goodarzy, Lida Zare Lahijan, Sanam Mohammadzadeh, Helena Mehran, Fatemeh Gheibi, Ramtin Shemshadigolafzani, Behnaz Dalvandi, Amir Abderam

“…However, the influence of outlier and influential studies warrants caution, and future studies should aim to further validate these findings in diverse clinical contexts. …”
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Prevalence of childhood overweight and obesity in Malaysia: a systematic review and meta-analysis by Ker Yang Chua, Ker Yung Chua, Karuthan Chinna, Chooi Ling Lim, Maheeka Seneviwickrama

“…In conclusion, the prevalence of childhood overweight, obesity, and excess weight in Malaysia doubled over 26 years. Future studies of the prevalence of childhood excess weight should follow a standardized reference for body mass index by age to ease interstudy comparisons.…”
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Psychosocial distress, perceived need and utilization of psycho- social support services in patients in the early phase after the first cancer diagnosis by Hannah Zingler, Diana Steinmann, Jochen Ernst, Ute Goerling, Myriel Hermann, Beate Hornemann, Anja Mehnert-Theuerkauf, Tanja Zimmermann

“…These should be investigated in more detail in future studies.…”
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Machine Learning in the Management of Patients Undergoing Catheter Ablation for Atrial Fibrillation: Scoping Review by Aijing Luo, Wei Chen, Hongtao Zhu, Wenzhao Xie, Xi Chen, Zhenjiang Liu, Zirui Xin

“…While guiding data preparation and model selection for future studies, this review highlights the need to address prevalent limitations, including lack of external validation, and to further explore model generalization and interpretability.…”
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Pre- and Post-Operative Pain Intensity and Physical Activity Levels in Individuals with Acetabular Dysplasia Undergoing Periacetabular Osteotomy: A Prospective Cohort Study by Naif Alrashdi, Robert Motl, Elroy Aguiar, Donald Lein Jr, Suzanne Perumean-Chaney, Michael Ryan, Matthew Ithurburn

“… # Conclusions Individuals with AD reported significant pain reduction at one month and up to six months after PAO, but PA levels did not change six months after PAO compared to baseline testing. Future studies should consider examining longitudinal pain recovery and PA improvements over longer periods of time with larger samples of individuals with AD undergoing PAO and identifying modifiable factors to minimize pain and increase PA participation…”
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Agreement Between Provider-Completed and Patient-Completed Preoperative Frailty Screening Using the Clinical Risk Analysis Index: Cross-Sectional Questionnaire Study by Mehraneh Khalighi, Amy C Thomas, Karl J Brown, Katherine C Ritchey

“…ConclusionsRAI-C had moderate agreement when completed by providers versus the participants themselves, with more than a third of patient-completed screens resulting in a higher frailty classification. Future studies will need to explore the differences between and accuracy of RAI-C screening approaches to inform best practices for preoperative RAI-C assessment implementation.…”
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Can muscle synergies shed light on the mechanisms underlying motor gains in response to robot-assisted gait training in children with cerebral palsy? by Gloria P. Vergara-Diaz, Stefano Sapienza, Jean-François Daneault, Eric Fabara, Catherine Adans-Dester, Giacomo Severini, Vincent C. K. Cheung, Carmen Echevarría Ruiz de Vargas, Donna Nimec, Paolo Bonato

“…However, no statistically significant correlations were identified at the group level. Future studies relying on larger datasets are needed to further investigate this observation and potential underlying mechanisms.…”
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Research trends in glioma chemoradiotherapy resistance: a bibliometric analysis (2003–2023) by Shishi Yu, Jinya Wu, Yuan Jing, Ping Lin, Lang Lang, Yifan Xiong, Wangzhong Chen, Wenhua Liu, Changpeng Sun, Yuntao Lu

“…This study represents the first comprehensive bibliometric analysis of this field, providing a detailed overview of research trends and potential directions for future studies. The findings highlight the need for strengthened international collaboration and multidisciplinary approaches to address the challenges of therapeutic resistance in glioma.…”
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Biological subphenotypes in patients hospitalized with suspected infection in Thailand: a secondary analysis of a prospective observational studyResearch in context by Prapassorn Poolchanuan, Taylor D. Coston, Viriya Hantrakun, Parinya Chamnan, Gumphol Wongsuvan, Pavan K. Bhatraju, Narisara Chantratita, Direk Limmathurotsakul, T. Eoin West, Shelton W. Wright

“…Patient subphenotype assignment was characterized by distinct clinical outcomes and biological profiles which could inform contextualized future study design. Funding: The US National Institutes of Health, the Wellcome Trust, and the Firland Foundation.…”
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The causal relationship of cigarette smoking to metabolic disease risk and the possible mediating role of gut microbiota by Jingda Zhang, Lin Hou, Shanxiang Lei, Yan Li, Guogang Xu

“…Conclusion: This work offered genetic evidence linking cigarette smoke to metabolic diseases, suggesting that the gut microbiota, particularly paraprevotella_clara, might be a crucial mediator in the development of type 2 diabetes caused by cigarette smoke. Our future studies should consider conducting other ethnic groups MR analyses, particularly with larger sample sizes. …”
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