Fifteen-second bouts of hyperoxia improve 5-minute time-trial performance in acute hypoxic conditions by Martin Faulhaber, Sina Schneider, Linda K. Rausch, Tobias Dünnwald, Verena Menz, Hannes Gatterer, Michael D. Kennedy, Wolfgang Schobersberger

“…Conclusion Repeated 15-second bouts of hyperoxia, applied during high-intensity exercise in hypoxia, are sufficient to increase power output. Future studies should focus on potential dose-response effects and the involved mechanisms. …”
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Analysis of early effects of human APOE isoforms on Alzheimer’s disease and type III hyperlipoproteinemia pathways using knock-in rat models with humanized APP and APOE by Metin Yesiltepe, Tao Yin, Marc Tambini, Hanmei Bao, Meixia Pan, Cristina d’Abramo, Luca Giliberto, Xianlin Han, Luciano D’Adamio

“…Minimal differences in lipid profiles between APOE3 hAβ and APOE4 hAβ rats reflect findings from mouse models. Future studies will include comprehensive lipidomic analyses in various CNS regions and at older ages to further validate these models and explore the effects of APOE isoforms on lipid metabolism in relation to AD pathology.…”
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Distribution of Airway Findings in ANCA-Associated Vasculitis: A 20-Year Observational Analysis by Megan M. Sullivan, Maximiliano Diaz Menindez, Hassan Baig, Anushka Irani, Ronald Butendieck, Benjamin Wang, Florentina Berianu, Carolyn Mead-Harvey, Andy Abril, Vikas Majithia

“…<b>Conclusion:</b> LCA shows promise in subtype stratification of AAV patients, yet its utility in predicting outcomes and guiding treatment remains limited based on our analysis. Future studies with enhanced phenotypic data and larger cohorts are warranted to improve predictive accuracy.…”
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Performance of a hybrid capture-based target enrichment next-generation sequencing for the identification of respiratory pathogens and resistance-associated genes in patients with... by Wei-Yu Hsu, Ting-Wei Kao, Hsin-Ching Cho, Sheng-Yuan Ruan, Tai-Fen Lee, Yu-Tsung Huang, Jung-Yien Chien

“…The study facilitated the implementation of molecular diagnosis by presenting real-world data, whereas future studies are mandated to generalize such an approach toward different clinical settings.…”
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Modeling Portfolio Optimization based on behavioral Preferences and Investor’s Memory by vahideh mousavi kakhki, Sanaz Khatabi

“…This study provides a foundation for future research on portfolio optimization. Future studies can explore other factors that influence investor behavior, such as social media sentiment and news sentiment. …”
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Long-Term Impact of Using Mobile Phones and Playing Computer Games on the Brain Structure and the Risk of Neurodegenerative Diseases: Large Population-Based Study by Yi Xiao, Sirui Zhang, Yuanzheng Ma, Shichan Wang, Chunyu Li, Yan Liang, Huifang Shang

“…Our research provides valuable background knowledge for future studies on the impact of modern electronic devices on brain health.…”
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The measurement of microplastics in surface water and their impact on histopathological structures in wading birds of district Lahore by Shaza Mehboob, Khalid Mahmood Anjum, Hamda Azmat, Muhammad Imran

“…The frequency and prevalence percentages followed the order: 0.5 mm &gt; 0.5–1 mm &gt; 1–2 mm &gt; 2–3 mm &gt; 3–4 mm &gt; 4–5 mm &gt; 0 mm (0 mm as control).This investigation contributes to the growing documentation of MPs abundance in freshwater ecosystems and provides a baseline for future studies on MPs pollution in the Ravi River.…”
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Triceps insertion violation from commonly applied olecranon plating system: a comparison by Ahmed A. Habis, MD, MSc, FRCSC, Kevin Nguyen, MASc, Julie Chan, MD, MHSc, FRCSC, Emad Anam, MD, MSc, FRCSC, Ryan T. Bicknell, MD, MSc, FRCSC, Heidi-Lynn Ploeg, PhD, PEng, FASME, FORS, Parham Daneshvar, MD, FRCSC

“…A better understanding of the triceps insertion footprint, olecranon anatomy, and clinical implications of triceps footprint disruption may lead to improvements in olecranon plate design and postoperative outcomes. Future studies should assess the possibility of any clinical implications of triceps insertion disruption.…”
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Hepatitis D virus infection triggers CXCL9-11 upregulation in hepatocytes and liver infiltration of CXCR3+ CD4 T cells by Jan-Hendrik Bockmann, Lena Allweiss, Annika Volmari, David da Fonseca Araújo, Matin Kohsar, Anastasia Hyrina, Janine Kah, Zhijuan Song, Josolyn Chan, Katja Giersch, Tassilo Volz, Marc Lütgehetmann, Jeffrey J. Wallin, Dmitry Manuilov, Meghan M. Holdorf, Simon P. Fletcher, Ansgar W. Lohse, Antonio Bertoletti, Julian Schulze zur Wiesch, Maura Dandri

“…The data of this study set hereby the basis for future studies analysing phenotype and function of intrahepatic T cells in CHD.…”
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Anti-LAG-3 antibody LBL-007 plus anti-PD-1 antibody toripalimab in advanced nasopharyngeal carcinoma and other solid tumors: an open-label, multicenter, phase Ib/II trial by Gang Chen, Dong-Chen Sun, Yi Ba, Ya-Xiong Zhang, Ting Zhou, Yuan-Yuan Zhao, Hong-Yun Zhao, Wen-Feng Fang, Yan Huang, Zhen Wang, Chao Deng, De-Sheng Hu, Wei Wang, Jin-Guan Lin, Gui-Ling Li, Su-Xia Luo, Zhi-Chao Fu, Hai-Sheng Zhu, Hui-Li Wang, Sheng-Li Cai, Xiao-Qiang Kang, Li Zhang, Yun-Peng Yang

“…These findings warrant further validation in future studies.…”
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Utilization of patient-reported outcomes to assess adherence to relugolix when combined with stereotactic body radiation therapy for intermediate to high-risk prostate cancer by Kelly Gaudian, Min Jung Koh, Min Ji Koh, Ryan R. Collins, Shaine Eden, Zoya Zwart, Malika Danner, Alan Zwart, Mark Fallick, Deepak Kumar, Paul Leger, Nancy A. Dawson, Simeng Suy, Sean P. Collins

“…Monitoring drug adherence during treatment allows for prompt detection of non-adherence and timely intervention. Future studies should focus on how to optimally incorporate this questionnaire into patient management.…”
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Transcriptomic Profiling and Tumor Microenvironment Classification Reveal Unique and Dynamic Immune Biology in HIV-Associated Kaposi Sarcoma by Jihua Yang, Ayse Ece Cali Daylan, Aleksei Shevkoplias, Ekaterina Postovalova, Meng Wang, Andrey Tyshevich, Matthew Lee, Hiba Narvel, Ksenia Zornikova, Nara Shin, Nikita Kotlov, Luca Paoluzzi, Changcheng Zhu, Balazs Halmos, Xingxing Zang, Haiying Cheng

“…The identification of a shared TCRβ chain suggests that immune T cells in KS patients may target a common antigen. Future studies should further explore the immune microenvironment and unique T cell clonotypes, which could pave the way for the development of novel therapeutic strategies for KS patients.…”
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Unveiling chemical industry secrets: Insights gleaned from scientific literatures that examine internal chemical corporate documents-A scoping review. by Miaoran Dong, Marc-André Gagnon

“…We shared our research findings on the Dataverse/ Borealis platform (https://doi.org/10.5683/SP3/EOIOAU), making them accessible for future studies to apply the same analytical framework seamlessly.…”
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Middle-age cerebral small vessel disease and cognitive function in later life: a population-based prospective cohort studyResearch in context by Ali Tanweer Siddiquee, Yoon Ho Hwang, Soriul Kim, Sung Jin Shin, Ji Soo Lee, June Christoph Kang, Min-Hee Lee, Hyeon Jin Kim, Seung Ku Lee, Chol Shin

“…Interpretation: Silent cSVD was independently associated with decline in executive functioning over 8-year follow-up period in this Korean middle-aged through elderly general population. Future studies considering wider spectrum of cSVD and longer follow-up durations may help predict further cognitive outcomes. …”
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Frailty Assessment Tools in Chronic Kidney Disease: A Systematic Review and Meta-analysis by Alisha Puri, Anita M. Lloyd, Aminu K. Bello, Marcello Tonelli, Sandra M. Campbell, Karthik Tennankore, Sara N. Davison, Stephanie Thompson

“…In order to make recommendations for frailty tools across measurement domains, future studies should compare the diagnostic accuracy to the clinical standard, geriatric assessment, and examine responsiveness to change.…”
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FERN: is it possible to conduct a randomised controlled trial of intervention or expectant management for early-onset selective fetal growth restriction in monochorionic twin pregn... by Kerry Woolfall, Jamie J Kirkham, Jane Sandall, Mariana Popa, Enrico Lopriore, Mark Turner, Shakila Thangaratinam, Aris T Papageorghiou, Andrew Sharp, Lawrence Impey, Andy Healey, Jessica Mendoza, Asma Khalil, Dharmintra Pasupathy, Brigitte Vollmer, Zarko Alfirevic, Rajeswari Parasuraman, Jan Deprest, Richard Edmund Ashcroft, Kurt Hecher, Smriti Prasad, Baskaran Thilaganathan, Richard J Jackson, Tracy Karen Mitchell, Natasha Fenwick, Monique C Haak, Liesbeth Lewi, Shauna Leven, Fabricio Da Silva Costa, Odai Yaghi, Tracey Ricketts, George Attilakos, Carolyn Bailie, Christine Cornforth, Mark Denbow, Louise Hardman, Jane Harrold, Joel Marsden, Tommy Mousa, Surabhi Nanda, Michelle Watson, Karen Wilding, Dilly Anumba, Edward D Johnstone, Yoav Yinon, Ahmet Baschat

“…The results from the FERN project will be used to inform future studies.Trial registration number This study is included in the ISRCTN Registry (ISRCTN16879394) and the NIHR Central Portfolio Management System (CPMS), CRN: Reproductive Health and Childbirth Specialty (UKCRN reference 47201).…”
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Evaluation of a 2-day First Aid Course Including Basic Resuscitation With 1,268 Primary School Children Aged 6–13 Years – A Multicenter Intervention Study

“…Conclusions: A 2-day course in a primary school setting showed considerable improvement in first aid and resuscitation skills of children aged 6–13 years. Future studies should examine these effects’ sustainability and the appropriate timing for refresher courses.   …”
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The intellectual paradigm and scientific mapping of brand image in International Researches by Maryam Najafi Yazdi, Seyed Hassan Hataminasab, Shahnaz Nayebzadeh

“…By collecting studies, the current research identifies important areas in the field of brand image, and provides solutions for future studies. Research method The current research was conducted with the aim of analyzing the intellectual paradigm and providing a scientific mapping of international research in the field of brand image. …”
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戶外冒險教育課程對大學生心理賦能之 成效研究 Effects of Integrating Psychological Empowerment Into an Outdoor Adventure Education Curriculum for College Students... by 蕭如軒 Ru-Syuan Hsia, 吳崇旗 Chung-Chi Wu

“…This suggests that gratitude and thankfulness are linked to psychological empowerment and should be explored in future studies. …”
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