Evaluation of a Novel Water-Based Automated Endoscope Cleaning Process Compared to Conventional Manual Cleaning for Reducing Duodenoscope Contaminatio by Koen van der Ploeg, Juliëtte A. Severin, Margreet C. Vos, Nicole S Erler, Adriana J.C. Bulkmans, Marco Bruno, Bibi C.G.C. Mason-Slingerland

“…These results are promising. However, future studies should confirm these findings in larger samples and explore the other advantages of using the AT in duodenoscope cleaning. …”
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Assessing psychological health and reproductive function: Depression, anxiety, and stress in infertile men compared to controls: A case-control study by Seyedeh Narjes Roudbaraki, Maryam Ramezani, Bita Saifi, Mostafa Salimi, Massood Issapour Cheshani

“…Limitations included phone-based data collection and the depression, anxiety, and stress scale 21 questionnaire’s screening nature. Future studies should involve larger populations and consider economic status as a variable related to mental health. …”
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Exposure pathways (diet, dissolved or particulate substrate) of rare earth elements to aquatic organisms by Ashlyn Kernaghan, Duc Huy Dang

“…Nevertheless, our results confirming preferential uptake pathways of the six organisms can help select appropriate species in future studies to monitor REE exposure from vaious fractions: dissolved, particulate forms or in the food webs (i.e., diet).…”
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The Association between Ambient Fine Particulate Matter and Oral Neoplasm among Smokers and Betel Quids Chewers by Mei-Sheng Ku, Pallop Siewchaisakul, Amy Ming-Fang Yen, Chen-Yu Liu

“…Subjects from areas of higher PM2.5 levels were found to have greater risk of OPMD/OC in Taiwan. Future studies are warranted to investigate the effect of personal PM2.5 exposure on OPMD/OC risk.…”
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Individualized drug therapy and survival prediction in ICU patients with acute kidney injury: construction and validation of a nomogram by Rui Yang, Xiaozhe Su, Ziqi Liu, Shuai Shao, Yinhuai Wang, Hao Su, Haiqing He

“…Conclusions In summary, the developed prediction model demonstrated accuracy for AKI patients in the ICU and helped clinical decision-making. However, future studies will require external validation to confirm these findings.…”
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Optimal needle characteristics for classical inferior alveolar nerve block anesthesia: a systematic review by Mennat Allah Ashraf Abd-Elsabour, Ayat Gamal-AbdelNaser

“…Clinical relevance Thinner needles are favored for less pain during insertion; but standardized future studies are essentially needed for solid conclusions. …”
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An Electronic Frailty Index Based on Deficit Accumulation May Predict Glaucomatous Visual Field Progression by Duy W, Pajewski N, Williamson JD, Thompson AC

“…Notably, baseline IOP was not associated with MD at baseline or the change in MD in the multivariable models.Conclusion: Glaucoma patients who are frail may be at higher risk of experiencing visual field decline, independent of baseline IOP. Future studies should investigate whether interventions to improve frailty can decrease risk of glaucoma progression.Keywords: glaucoma, electronic frailty index, visual field…”
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Association of objective and subjective socioeconomic markers with cognitive impairment among older adults: cross-sectional evidence from a developing country by Shobhit Srivastava, T Muhammad, TV Sekher

“…Interaction analyses revealed that older adults who belonged to lower subjective and objective (poorest MPCE quintile, Scheduled Castes and lowest education) SES had 2.45 (CI: 1.77 to 3.39), 4.56 (CI: 2.97 to 6.98) and 54.41 (CI: 7.61 to 388.93) higher odds of cognitive impairment than those from higher subjective and objective SES, respectively.Conclusion Subjective measures of SES were linked to cognitive outcomes, even more strongly than objective measures of SES; considering the relative ease of obtaining such measures, subjective SES measures are a promising target for future study on socioeconomic indicators of cognitive impairment.…”
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Evaluating Mirror Therapy Protocols in Phantom Limb Pain Clinical Trials: A Scoping Review by Limakatso K, McGowan E, Ortiz-Catalan M

“…Establishing a standardized treatment protocol could enhance the reliability and reproducibility of treatment outcomes in future studies and ensure a meaningful comparison between mirror therapy and other treatments in clinical trials and meta-analyses.Keywords: amputation, phantom limb pain, mirror therapy, rehabilitation…”
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Zinc levels in severe eating disorders by Kara Leach, Dan V. Blalock, Judy Oakes, Melanie Hebert, Marina Foster, Philip S. Mehler

“…These characteristics make zinc an intriguing focus of future study that could impact the recidivism rate in severe ED. …”
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Effect of a Novel Training Program in Patients With Chronic Shoulder Pain Based on Implicit Motor Learning: Pilot and Feasibility Study. by Annelies Maenhout, Wieger Heijenk, Peter Glashouwer, Lore Quatacker, Luna Praet, Dorien Borms

“…Both feasibility and clinical effects of the program on pain and function was acceptable. Future studies should incorporate a control group, provide longer follow up and include objective measurements…”
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An exergy-based analysis for the synthesis of aromatics from biomass by Mohammed Usman, Joseph Akintola, Gabriel Umoh, Joseph Akpan, Ekpotu Wilson, Queen Moses, Philemon Udom, Edose Osagie

“…This study demonstrates the two process routes’ long-term economic viability and efficiency, which can be further optimised in future studies to achieve sustainable process implementation.…”
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Nurses retention: the impact of transformational leadership, career growth, work well-being, and work-life Balance by Eman Sameh AbdELhay, Samah Mohamed Taha, Mona Metwally El-Sayed, Sahar Hassan Helaly, Islam Sameh AbdELhay

“…Healthcare institutions should focus on transformational leadership and work-life balance to enhance nurse retention. Future studies should explore factors related to career growth and work well-being to determine their potential impact on retention.…”
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Impact of elexacaftor-tezacaftor-ivacaftor in lung transplantation for cystic fibrosis in the United States by Tahuanty A. Pena, MD, MS, Brittany Wright, PharmD, Kalpaj R. Parekh, MBBS, Julia Kleney-Tait, MD, PhD

“…These findings underscore the transformative impact of CFTR modulators like ETI on the natural history of CF, highlighting the importance of continued advancements in precision medicine for genetic disorders. Future studies should investigate long-term outcomes and sustained trends in lung transplantation needs among pwCF.…”
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Real-World Treatment Patterns in Men with Castration- Resistant Prostate Cancer Receiving Docetaxel by Keith L. Davis, Benjamin Gutierrez, Teresa Zyczynski, James A. Kaye

“…However, one quarter of patients did not initiate docetaxel until ≥6 months after CRPC diagnosis and total exposure varied considerably, with only 10% receiving ≥10 cycles. Future studies are needed to describe specific reasons explaining timing of docetaxel initiation and duration of exposure in some CRPC patients.…”
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Development of Predictive Models for Progression from Diabetic Kidney Disease to End-Stage Renal Disease in Type 2 Diabetes Mellitus: A Retrospective Cohort Study by Hu H, Mu X, Zhao S, Yang M, Zhou H

“…Additionally, the combined model of KFRE, IFTA, SII, and BMI demonstrates high predictive performance. Future studies should validate these models in larger cohorts and explore their integration into routine clinical practice to enhance personalized risk assessment and management.Keywords: diabetic kidney disease, end-stage renal disease, pathologies, risk assessment…”
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Successful management of refractory epilepsy in creatine transporter deficiency with cannabidiol and clobazam: A case report by Maria Borrell‐Pichot, Carmen Fons, Susana Boronat, Alba Sierra‐Marcos

“…This calls for more extensive research and suggests a possible role for CBD in cerebral creatine metabolism and transport and valuable option for future studies. Plain Language Summary Creatine transporter deficiency (CRTR‐D) is a rare genetic disorder causing mental, behavioral, and movement problems. …”
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Novel insights into palatal shelf elevation dynamics in normal mouse embryos by Jeremy P. Goering, Michael Moedritzer, Marta Stetsiv, Dona Greta Isai, Brittany M. Hufft-Martinez, An J. Tran, Zaid Umar, Madison K. Rickabaugh, Paul Keselman, Munish Chauhan, Pamela V. Tran, William M. Brooks, William M. Brooks, Kenneth J. Fischer, Andras Czirok, Andras Czirok, Irfan Saadi, Irfan Saadi

“…Thus, our data reveal novel insights into rapid dynamic changes during PS elevation, and lay the foundation for future studies of normal and abnormal palatogenesis.…”
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Does a Provider Contact Wristband Reduce Emergency Department Visit Rates Following Hip or Knee Arthroplasty? by David C. Hein, MD, Ajay K. Srivastava, MD, Seann E. Willson, MD, Paul M. Telehowski, MD, Patrick J. Atkinson, PhD, Theresa S. Atkinson, PhD

“…Conclusions: Patients utilized the wristband number, but this did not significantly reduce the number of ED visits within 3 years. Future studies should track ED visits and identify decision-making factors behind ED use in order to find ways to improve the intervention.…”
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Phytomedicinal armamentarium: A review of inula racemosa-derived alantolactones and isoalantolactones in anticancer therapy by Joshi Gaurav Santoshrao, Smriti Jamwal, Rakesh Kumar, Ekta Bisht, Bisen Harsh Krishnakumar, Shreya Katoch, R.K. Asrani

“…Their diverse mechanisms of action and minimal side effects position them as candidates for further research and development. Future studies should focus on clinical trials to establish their efficacy and safety in humans, paving the way for new cancer therapies.…”
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