Prognostic Implications of the Number of Lymph Node Metastases in Oral Tongue Squamous Cell Carcinoma: A Population Study of the SEER Database and an Institutional Registry by Wenjie Huang, Yu Zhang, Hao Li, Zhiying Liang, Shumin Zhou, Jie Pan, Hui Xie, Chao Luo, Shuqi Li, Guangying Ruan, Fei Ai, Yanfeng Chen

“…Conclusion The number of PLNs is a better predictor of overall tumor burden for OTSCC and could be a more accurate metric for survival estimation, which should be considered in future simplified pathological nodal staging for better risk stratification and decision‐making in subsites of the oral cavity.…”
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Assessing Knowledge and Preventive Practices Regarding Infectious Diseases Among Healthcare Workers in Hail City, Saudi Arabia by Sandro Costanilla Villareal

“…However, ongoing education and training are crucial to ensure that all healthcare workers possess the necessary knowledge and skills to respond effectively to future health crises. Keywords: COVID-19, healthcare workers, impact, pandemic, precautionary health behaviors   Abstrak Menilai Pengetahuan dan Praktik Pencegahan Penyakit Menular pada Petugas Kesehatan di Kota Hail, Arab Saudi. …”
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Microsatellite analyses reveal genetic diversity and population structure of Cipangopaludina chinensis in Guangxi, China by Xiao-kai Wei, Kang-qi Zhou, Xin-xi Zou, Xue-ling Zhang, Yu-Sen Li, Hui Luo, Yin Huang, Xue-song Du, Jun-qi Qin, Zhong Chen, Yong Lin, Xian-hui Pan, Hua Ye

“…These findings provide important genetic information for C. chinensis and a theoretical basis for future protection and selective breeding between different geographical populations.…”
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Implementation of a genotyped African population cohort, with virtual follow-up: A feasibility study in the Western Cape Province, South Africa [version 2; peer review: 2 approved,... by Robert J Wilkinson, Francisco Lakay, Nicki Tiffin, Joel A Dave, Catherine Riou, Peter Raubenheimer, Anna K Coussens, Tsaone Tamuhla, Melissa J Blumenthal, Maleeka Abrahams

“…Conclusions The results shown here are illustrative of what will be possible as the cohort expands in the future. Here we demonstrate the feasibility of this approach, recognising that the findings presented here are preliminary and require further validation once we have a sufficient sample size to improve statistical significance of findings. …”
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Integrating multi‐omics features enables non‐invasive early diagnosis and treatment response prediction of diffuse large B‐cell lymphoma by Weilong Zhang, Bangquan Ye, Yang Song, Ping Yang, Wenzhe Si, Hairong Jing, Fan Yang, Dan Yuan, Zhihong Wu, Jiahao Lyu, Kang Peng, Xu Zhang, Lingli Wang, Yan Li, Yan Liu, Chaoling Wu, Xiaoyu Hao, Yuqi Zhang, Wenxin Qi, Jing Wang, Fei Dong, Zijian Zhao, Hongmei Jing, Yanzhao Li

“…Conclusions Our study provides an effectively improved approach with high accuracy for the diagnosis and prognosis of DLBCL, showing great potential for future clinical application. Key points A comprehensive multi‐omics solution to specifically obtain an extensive fragmentomics landscape, presented by breakpoint characteristics of nucleosomes, CpG islands, DNase clusters and enhancers, besides typical methylation, copy number alteration of cfDNA. …”
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Advancing life cycle assessment of bioenergy crops with global land use models by Anders Arvesen, Florian Humpenöder, Tomás Navarrete Gutierrez, Thomas Gibon, Paul Baustert, Jan Philipp Dietrich, Konstantin Stadler, Cristina-Maria Iordan, Gunnar Luderer, Alexander Popp, Francesco Cherubini

“…Thanks to a global spatial coverage and temporal dimension, it facilitates a systematic and consistent inclusion of indirect effects in a global analysis framework. Future research can build on our open-source data/software to study different regions, bioenergy products or impacts.…”
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Global biogeography of N₂-fixing microbes: <i>nifH</i> amplicon database and analytics workflow by M. Morando, J. D. Magasin, S. Cheung, S. Cheung, M. M. Mills, J. P. Zehr, K. A. Turk-Kubo

“…The workflow and <i>nifH</i> ASV database provide a robust framework for studying marine <span class="inline-formula">N₂</span> fixation and diazotrophic diversity captured by <i>nifH</i> amplicon HTS. Future datasets that target understudied ocean regions can be added easily, and users can tune parameters and studies included for their specific focus. …”
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Effectiveness–implementation hybrid-2 randomised trial of a collaborative Shared Care Model for Detecting Neurodevelopmental Impairments after Critical Illness in Young Children (D... by Paula Lister, Kristen Gibbons, Zephanie Tyack, Luregn J Schlapbach, Samudragupta Bora, Maria Isabel Castillo, James Best, Debbie Long, Helen G Liley, Belinda Dow, Kerri-Lyn Webb, Christian Stocker, Debra Thoms, Carolyn Wharton, Lori Matuschka

“…The present study intends to pilot a combined multidisciplinary, online screening platform and general practitioner (GP) shared care neurodevelopmental follow-up model to determine feasibility of a larger, future study. We will also assess the difference between neurodevelopmental vulnerability and parental stress in two intervention groups and the impact of child, parent, sociodemographic and illness/treatment risk factors on child and parent outcomes.Methods and analysis Single-centre randomised effectiveness–implementation (hybrid-2 design) pilot trial for parents of children aged ≥2 months and &lt;4 years discharged from PICU after critical illness or injury. …”
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Coronary Heart Disease Risk Prediction Model Based on Machine Learning by YUE Haitao, HE Chanchan, CHENG Yuyou, ZHANG Sencheng, WU You, MA Jing

“…Among them, the XGBoost model exhibited superior performance and can be referenced for future optimization of CHD prediction models. Additionally, considering the excellent performance of the XGBoost model and the convenience and interpretability of stepwise logistic regression, a combined use of these approaches after data balancing is recommended in CHD risk prediction models.…”
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Inpatient dialectical behavior therapy combined with trauma-focused therapy for PTSD and borderline personality disorder symptoms: study design of the naturalistic trauma therapy s... by Annemieke C. Kamstra, Annemieke C. Kamstra, Sybolt O. de Vries, Maarten F. Brilman, Petty Vasilev, Manna A. Alma, Antoinette D. I. van Asselt, Antoinette D. I. van Asselt, Mia De Wolf, Robert A. Schoevers, Frederike Jörg

“…In addition, it provides insight into individual symptom trajectories and experiences, inspiring future treatment improvements for clients with severe psychopathology.Trial registrationMedical Ethical Committee approval (NL669060018, RTPO1044/01.10.2018). …”
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Vertical bacterial variability in oxidation ponds in the tropical zone by C. Tudsanaton, T. Pattamapitoon, O. Phewnil, W. Wararam, K. Chunkao, P. Maskulrath, M. Srichomphu

“…The knowledge gained from this study can be used as a reference in future works on natural wastewater treatment systems.…”
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Oral Administration of 17α-Methyltestosterone Increased Male Percentage of Freshwater Crayfish Cherax quadricarinatus by O. Carman, M.Y. Jamal, . Alimuddin

“… Cherax quadricarinatus is one of freshwater crayfish species that has enormous potential for expanding its farming in future.  Application of monosex male culture using steroid sex hormone administration method during the period of sex differentiation or early developmental stage might be increased efficiency in farming.  …”
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Evaluasi TKTI Puri Saron Hotel Seminyak dengan Framework Cobit 5 by Norsa Yudhi Arso, Made Wisnu Antara Kesiman, Dewa Gede Hendra Divayana

“…The findings of the analysis are centered on the COBIT Process, specifically the domains (EDM04) IT Resources, (APO01) Consistency Management, (APO03) IT Architecture, (APO04) IT Innovation, (APO07) Resource Management, (BAI04) Balancing Flows and Future Needs , (BAI09) Company Assets, (BAI10) Configuration Management, (DSS01) Operations Management, (DSS03) Managing Company Life Cycle Problems, and ( The process of planning, assessing and adjusting Puri Saron Hotel Seminyak for a better direction, and most of the domain activities have been executed, policies and norms have been written, and communication has improved. …”
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Concentration-dependent effects of immunomodulatory cocktails on the generation of leukemia-derived dendritic cells, DCleu mediated T-cell activation and on-target/off-tumor toxici... by Hazal Aslan Rejeski, Hazal Aslan Rejeski, Anne Hartz, Anne Hartz, Elias Rackl, Elias Rackl, Lin Li, Lin Li, Christoph Schwepcke, Christoph Schwepcke, Kai Rejeski, Kai Rejeski, Christoph Schmid, Christoph Schmid, Andreas Rank, Andreas Rank, Jörg Schmohl, Doris Kraemer, Peter Bojko, Helga Maria Schmetzer, Helga Maria Schmetzer

“…In conclusion, our results highlight that Kit-mediated DC/DCleu generation, immune cell activation and blast lysis are dependent on the concentration of response modifiers, which will guide future clinical development. Overall, DCleu-based immunotherapy represents a promising treatment strategy for AML patients.…”
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Hepatocellular carcinoma risk scores for non-viral liver disease: A systematic review and meta-analysis by Laura Burke, Alexander Hinkson, Vincent Haghnejad, Rebecca Jones, Richard Parker, Ian A. Rowe

“…This study highlights these critical issues that may hinder the implementation of risk models in clinical practice and offers key recommendations for future model development studies.…”
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HbA1c Cutoff Point of 5.9% Better Identifies High Risk of Progression to Diabetes among Chinese Adults: Results from a Retrospective Cohort Study by Kai Liang, Chuan Wang, Fei Yan, Lingshu Wang, Tianyi He, Xiuping Zhang, Chengqiao Li, Weifang Yang, Zeqiang Ma, Aixia Ma, Xinguo Hou, Li Chen

“…The HbA1c cutoff points were evaluated to predict the future risks of diabetes. Relative risk (RR) was calculated using the chi-square test. …”
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Unequal ageing: the quality of life of senior citizens in the EU before and after COVID-19. A multidimensional approach by Elżbieta Roszko-Wójtowicz, Klaudia Przybysz, Agnieszka Stanimir

“…The disparities underscore the need for more balanced and equitable policy interventions that can address the vulnerabilities of older populations, particularly in regions struggling with economic instability. Future research should focus on longitudinal studies that track the recovery trajectories of seniors post-pandemic and assess the effectiveness of policy measures aimed at mitigating these disparities.…”
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Travellers’ adherence to atovaquone/proguanil malaria chemoprophylaxis after return from endemic areas by Jenny Lea Schnyder, David Cornelis Birkhoff, Myrthe Celine Jarings, Sabine Margot Hermans, Martin Peter Grobusch, Hanna Katrien de Jong

“…Travellers preferred an alternative AP chemoprophylaxis regimen, allowing them to discontinue upon return. Future research shall be conducted to investigate whether AP could be discontinued upon return.…”
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Phthalates esters disrupt demersal fish behavior: Unveiling the brain-gut axis impact by Liuqingqing Liu, Xinyao Li, Xianxiang Luo, Xiao Wang, Linjia Liu, Zixi Yuan, Cuizhu Sun, Hao Zheng, Elvis Genbo Xu, Fengmin Li

“…We also stress the crucial need for further research on fish and other marine species beyond the laboratory scale to fully understand the broader implications of PAE exposure in marine ecosystems and to guide future conservation efforts.…”
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Research hotspots and trends in the field of quality of life of oral cancer patients: A visual analysis based on CiteSpace (基于CiteSpace口腔癌患者生活质量研究热点的可视化分析)... by YANG Ting (杨婷), CHEN Siyi (陈思忆), ZHENG Xiaodan (郑晓丹), YANG Yi (杨怡)

“…Conclusion It is recommended that researchers learn from the advanced theories and models of foreign countries to further develop a quality of life assessment scale more suitable for oral cancer patients in China. In the future, the main focus should be on personalized treatment plans, rehabilitation training methods and management, supportive care needs, and body imagery changes so as to better improve the quality of life of oral cancer patients. …”
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