Pilot study of a ketogenic diet in bipolar disorder: a process evaluation by Benjamin P. Rigby, Nicole Needham, Helen Grossi, Ivana Kamenska, Iain H. Campbell, Ben Meadowcroft, Frances Creasy, Cheryl Fisher, Pankaj Bahuguna, John Norrie, Gerard Thompson, Melissa C. Gibbs, Maja Mitchell-Grigorjeva, Ailsa McLellan, Tessa Moses, Karl Burgess, Rachel Brown, Michael J. Thrippleton, Harry Campbell, Daniel J. Smith, Sharon A. Simpson

“…Conclusion We provide novel insight into the experiences of people living with bipolar disorder initiating and following a ketogenic diet, as well as those of research clinicians who support the intervention. Future trials may benefit from increased clinical research capacity, better-defined entry and exit routes, additional interpersonal support, and greater understanding of how social and societal factors impact participation. …”
Get full text

Comparative microbial metagenomic analysis of drinking water plants and wastewater treatment plants in Istanbul by Mehmet Demirci, Cankut Çubuk, Ferhat Dasdemir, Abdulkerim Suat Saribas, Esra Billur Balcıoglu, Dogukan Ozbey, Dogu Yorulmaz, Tugba Olmez Hanci, Safak Basa, Bekir Sami Kocazeybek, Bekir Sami Kocazeybek

“…The data could serve as preliminary information for future research. More extensive studies are needed, with multiple sample tracking in these facilities and their feeding basins.…”
Get full text

Unambiguous identification of fungi: where do we stand and how accurate and precise is fungal DNA barcoding? by Robert Lücking, M. Catherine Aime, Barbara Robbertse, Andrew N. Miller, Hiran A. Ariyawansa, Takayuki Aoki, Gianluigi Cardinali, Pedro W. Crous, Irina S. Druzhinina, David M. Geiser, David L. Hawksworth, Kevin D. Hyde, Laszlo Irinyi, Rajesh Jeewon, Peter R. Johnston, Paul M. Kirk, Elaine Malosso, Tom W. May, Wieland Meyer, Maarja Öpik, Vincent Robert, Marc Stadler, Marco Thines, Duong Vu, Andrey M. Yurkov, Ning Zhang, Conrad L. Schoch

“…In parallel, technological improvements to genome sequencing offer promising alternatives to DNA barcoding in the future. Despite the prevalence of DNA-based fungal taxonomy, phenotype-based approaches remain an important strategy to catalog the global diversity of fungi and establish initial species hypotheses.…”
Get full text

Pengukuran Kapabilitas Tata Kelola TI Sistem Informasi Tiras dan Transaksi Bahan Ajar Universitas Terbuka Menggunakan Cobit 5 by Denisha Trihapningsari, Dewi Agushinta R., Lintang Yuniar Banowosari

“…This research produces measurement of IT process capability level in selected COBIT 5 domains, analysis of organizational conditions to achieve process capability level, improvement priority criteria, and recommendations for improvement for each process to achieve optimizing process capability level (level 5) in the near future. …”
Get full text

Persistent and emerging threats to Arctic biodiversity and ways to overcome them: a horizon scan by Tanya A. Lemieux, Jackson D.R. Coles, Anne L. Haley, Michelle L. LaFlamme, Sara K. Steel, Kara M. Scott, Jennifer F. Provencher, Courtney Price, Joseph R. Bennett, Isabel C. Barrio, Helen S. Findlay, Simon J. Goodman, Blake Matthews, Joacim Näslund, David. A. Pearce, Robert D. Hollister, Mark L. Mallory, Paul A. Smith, Gabriela Schaepman-Strub, Steven J. Cooke

“…., a lack of fundamental information regarding Arctic biodiversity) needing attention and is intended to guide future conservation action within the Arctic.…”
Get full text

Development of a latency model for HIV-1 subtype C and the impact of long terminal repeat element genetic variation on latency reversal by Shreyal Maikoo, Robert-Jan Palstra, Krista L. Dong, Tokameh Mahmoudi, Thumbi Ndung'u, Paradise Madlala

“…Our data suggests that genetic variation both within and between HIV-1 subtypes influences latency reversal. Future studies should investigate the specific role of variation in host cellular environment on reactivation differences.…”
Get full text

Nurses' self-efficacy and outcome expectancy in evidence-based practice: Translation, construct validity and internal consistency of the Dutch scales by Peter Hoegen, Michael Echteld, Cindy de Bot, Annemarie de Vos, Derya Demirçay, Mary-Anne Ramis, Lidwine Mokkink, Hester Vermeulen

“…Conclusions: Construct validity and internal consistency of the Dutch Self-efficacy and Outcome Expectancy in EBP Scales are good. Future research should prioritize responsiveness and test-retest reliability.…”
Get full text

Gut microbiota and inflammasome-mediated pyroptosis: a bibliometric analysis from 2014 to 2023 by Hang Zhang, Hang Zhang, Hang Zhang, Tian Zhao, Tian Zhao, Tian Zhao, Juan Gu, Juan Gu, Fushan Tang, Fushan Tang, Fushan Tang, Lei Zhu, Lei Zhu, Lei Zhu

“…Over the past decade, the exploration of how gut microbiota and NLRP3 or NLRP6 inflammasome-mediated pyroptosis has been an area of interest. Future investigations in this filed may primarily revolve around understanding the correlation between butyrate and NLRP3 inflammasome induced pyroptosis in relation to conditions. …”
Get full text

Analysis of early effects of human APOE isoforms on Alzheimer’s disease and type III hyperlipoproteinemia pathways using knock-in rat models with humanized APP and APOE by Metin Yesiltepe, Tao Yin, Marc Tambini, Hanmei Bao, Meixia Pan, Cristina d’Abramo, Luca Giliberto, Xianlin Han, Luciano D’Adamio

“…Minimal differences in lipid profiles between APOE3 hAβ and APOE4 hAβ rats reflect findings from mouse models. Future studies will include comprehensive lipidomic analyses in various CNS regions and at older ages to further validate these models and explore the effects of APOE isoforms on lipid metabolism in relation to AD pathology.…”
Get full text

The two-component system ArlRS is essential for wall teichoic acid glycoswitching in Staphylococcus aureus by Marieke M. Kuijk, Emma Tusveld, Esther Lehmann, Rob van Dalen, Iñigo Lasa, Hanne Ingmer, Yvonne Pannekoek, Nina M. van Sorge

“…Since WTA represents a promising target for future immune-based treatments and vaccines, our findings provide important insight to align strategies targeting S. aureus WTA glycosylation patterns during infection.IMPORTANCEStaphylococcus aureus is a common colonizer but can also cause severe infections in humans. …”
Get full text

Spatial Analysis of Building Density and Liquefaction Spread in Izmit Bay and its Surroundings by Arzu Erener, Metin Aşcı, Gül Gülsoy, Aydın Üstün, Muhammed Ali Güvenaltın, Erman Şentürk, Sefa Yalvaç, Fatma Canaslan Çomut, T. Serkan Irmak, Haluk Konak, Pakize Küreç Nehbit, Efdal Kaya, Burak Kotan, Selin Öye

“…The study is important in terms of taking sustainable precautions against future natural disasters, preparing precaution plans for the speed and density of construction, determining the current situation of building and ground liquefaction around Gölcük and Izmit Bay, taking engineering measures in risky areas and providing building and life safety and creating a basis for disaster assessments.…”
Get full text

Integrative deep immune profiling of the elderly reveals systems-level signatures of aging, sex, smoking, and clinical traitsResearch in context by Lennart Riemann, Rodrigo Gutierrez, Ivan Odak, Joana Barros-Martins, Lennart M. Roesner, Ximena Leon Lara, Christine Falk, Thomas F. Schulz, Gesine Hansen, Thomas Werfel, Reinhold Förster, Berislav Bošnjak, Felix Jenniches, Norman Klopp, Till Robin Lesker, Martin Stangel

“…Our findings highlight clinically relevant immune signatures that enhance our understanding of aging-related diseases and could guide future research into new treatments, offering translational insights into human health and aging. …”
Get full text

Diversity and seasonal variation of zooplankton community in a large deep-water reservoir of Eastern China using eDNA and morphological methods by Lei Hao, Lei Hao, Xinting Xu, Xinting Xu, Yan Zhou, Yan Zhou, Dan Liu, Dan Liu, Jianqiang Shao, Jiayong Pan, Guangxi He, Zhongjun Hu, Zhongjun Hu, Qigen Liu, Qigen Liu

“…Although eDNA cannot yet replace morphological methods, its efficiency and sensitivity make it a valuable complementary tool for zooplankton monitoring, with considerable potential for future applications.…”
Get full text

Effect of interface morphology on tensile response of Ti6Al4V alloy fabricated by laser hybrid additive manufacturing: Experiments & simulations by Wei Fan, Guang Hu, Yuguang Chen, Yue Du, Yijie Peng, Yongxia Wang, Yunlong Li, Hua Tan, Fengying Zhang, Xin Lin

“…The findings provide a framework for optimizing interface design to improve mechanical performance, offering insights for future advancements in additive manufacturing of components with inhomogeneous microstructure.…”
Get full text

Our Fascinating and Complex World by Jackson Kelly

“…Over the past two years, I have focused on documenting the ongoing wars in Gaza and Ukraine. I engage with my future major, Political Science, and career daily, preparing myself for the rigor of higher education. …”
Get full text

Advances of wearable silicone rubber-based triboelectric nanogenerators: from manufacturing to application by Dianlong Shen, Taili Du, Fangyang Dong, Hu Cai, Aziz Noor, Xiannan Du, Yongjiu Zou, Chengkuo Lee, Minyi Xu

“…Additionally, this article discusses the current challenges in the SR-TENG fabrication technology and potential future directions, aiming to promote the effective development of SR-TENGs in biomechanical energy harvesting and self-powered sensing applications.…”
Get full text

Large‐Vessel Occlusion Stroke Knowledge and Training for Stroke Severity Assessment Among Emergency Medical Services Personnel in the United States by Kaiz S. Asif, Robin Novakovic, Thanh N. Nguyen, Santiago Ortega‐Gutierrez, Youngran Kim, Amanda Jagolino‐Cole, Sushanth Aroor, Alicia Castonguay, Prateek Kumar, Ashutosh P. Jhadav, Dileep Yavagal, May Nour, Gabor Toth, Maxim Mokin, Sunil A. Sheth, Mouhammad A. Jumaa, Alhamza Al‐bayati, Mohamed Teleb, Ossama Y. Mansour, Shashvat M. Desai, Joshua Hartman, David S. Liebeskind, Ameer E. Hassan, Brijesh P. Mehta

“…We conducted a nationwide EMS survey across the United States to glean insights that can inform and customize future EMS educational efforts. Methods The Society of Vascular and Interventional Neurology, in collaboration with EMS World, created an online questionnaire for EMS personnel. …”
Get full text

Diabetes distress among immigrants of south Asian descent living in New York City: baseline results from the DREAM randomized control trial by Farhan Mohsin, Laura Wyatt, Hayley Belli, Shahmir Ali, Deborah Onakomaiya, Supriya Misra, Yousra Yusuf, Shinu Mammen, Jennifer Zanowiak, Sarah Hussain, Haroon Zafar, Sahnah Lim, Nadia Islam, Naheed Ahmed

“…Screening for DD in patients with prediabetes or diabetes should be integrated to address mental and physical health needs. Future research can benefit from a longitudinal analysis of the impact of DD on diabetes self-management and health outcomes. …”
Get full text

Effects of Mixing Tree Species on Soil Enzyme Activity and Carbon-Use Efficiency in Eroded Masson Pine Forest by WANG Man, JIANG Yongmeng, ZHANG Shiliang, ZHANG Jinxiu, ZHENG Linmin, ZENG Zhiwei, LYU Maokui, XIE Jinsheng

“…Therefore, the differences between pure forest and secondary forest should be considered in future management and research of P. massoniana forest.…”
Get full text

Laying the groundwork: Exploring pesticide exposure and genetic factors in south-eastern Brazilian farmers by Débora Dummer Meira, Victor Nogueira Da Gama Kohls, Matheus Correia Casotti, Luana Santos Louro, Gabriel Mendonça Santana, Thomas Erik Santos Louro, Adriana Madeira Alvares da Silva, Lorena Souza Castro Altoé, Raquel Reis Trabach, Sonia Groisman, Elizeu Fagundes de Carvalho, Jamila Alessandra Perini Machado, Stephanie Seneff, Iúri Drumond Louro

“…As an introductory effort, this study provides insights into the complex relationship between genetic variations and pesticide exposure, laying the groundwork for future research. This pioneering work on associations between specific genetic variations and health risks with pesticide exposure, emphasizes the importance of personalized medicine and stricter regulation of pesticide use for public health and occupational safety.…”
Get full text