Fifteen-second bouts of hyperoxia improve 5-minute time-trial performance in acute hypoxic conditions by Martin Faulhaber, Sina Schneider, Linda K. Rausch, Tobias Dünnwald, Verena Menz, Hannes Gatterer, Michael D. Kennedy, Wolfgang Schobersberger

“…Conclusion Repeated 15-second bouts of hyperoxia, applied during high-intensity exercise in hypoxia, are sufficient to increase power output. Future studies should focus on potential dose-response effects and the involved mechanisms. …”
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Maximum ozone concentrations in the southwestern US and Texas: implications of the growing predominance of the background contribution by D. D. Parrish, I. C. Faloona, I. C. Faloona, R. G. Derwent

“…Second, the predominant contribution of US background ozone across the southwestern US presents a profound challenge for air quality modeling, as a manifold of stratospheric and tropospheric processes occurring at small spatial scales but over hemisphere-wide distances must be accurately treated in detail to predict present and future background contributions to daily maximum ozone concentrations at local scales.…”
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Development of a clinical prediction model for benign and malignant pulmonary nodules with a CTR ≥ 50% utilizing artificial intelligence-driven radiomics analysis by Wensong Shi, Yuzhui Hu, Guotao Chang, He Qian, Yulun Yang, Yinsen Song, Zhengpan Wei, Liang Gao, Hang Yi, Sikai Wu, Kun Wang, Huandong Huo, Shuaibo Wang, Yousheng Mao, Siyuan Ai, Liang Zhao, Xiangnan Li, Huiyu Zheng

“…Conclusion The model has moderate accuracy in differentiating benign from malignant 3D CTR ≥ 50% nodules, holding clinical potential. Future efforts could explore more to improve its precision and value. …”
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Mountain sentinels in a changing world: Review and conservation implications of weather and climate effects on mountain goats (Oreamnos americanus) by Kevin S. White, Becky Cadsand, Steeve D. Côté, Tabitha Graves, Sandra Hamel, Richard B. Harris, Forest P. Hayes, Eran Hood, Kevin Hurley, Tyler Jessen, Bill Jex, Erich Peitzsch, Wesley Sarmento, Helen Schwantje, Joel Berger

“…Cold-adapted, mountain species are at risk due to forecasted change and knowledge is needed to respond to current and future conservation challenges. Mountain goats (Oreamnos americanus) are an iconic species of North American mountain cultures and landscapes, and due to specialized adaptations for life in cold, mountainous environments they are particularly sensitive to changes in weather and climate. …”
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Reproduction performance of climbing perch Anabas testudineus F1 and F2 broodstock with different dietary supplementation by Helmizuryani, Helmizuryani, Boby Muslimin, Khusnul Khotimah

“…This species is potential to create the sustainability production in the future because they offer a promising price, so it needs a further study for optimizing the quality of broodstock and its offsprings. …”
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Phenotypic Trajectories From Acute to Stable Phase in Heart Failure With Preserved Ejection Fraction: Insights From the PURSUIT‐HFpEF Study by Yuki Matsuoka, Yohei Sotomi, Daisaku Nakatani, Katsuki Okada, Akihiro Sunaga, Hirota Kida, Taiki Sato, Daisuke Sakamoto, Tetsuhisa Kitamura, Sho Komukai, Masahiro Seo, Masamichi Yano, Takaharu Hayashi, Akito Nakagawa, Yusuke Nakagawa, Shunsuke Tamaki, Yoshio Yasumura, Takahisa Yamada, Shungo Hikoso, Yasushi Sakata

“…This grouping can be a basis for future precision medicine of patients with HFpEF. …”
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Imaging Spectroscopy: Earth and Planetary Remote Sensing with the PSI Tetracorder and Expert Systems from Rovers to EMIT and Beyond by Roger N. Clark, Gregg A. Swayze, K. Eric Livo, Philip G. Brodrick, Eldar Noe Dobrea, Srinivasan Vijayarangan, Robert O. Green, David Wettergreen, Alberto Candela, Amanda Hendrix, Carlos Pérez García-Pando, Neil C. Pearson, Melissa D. Lane, Adolfo González-Romero, Xavier Querol, the EMIT and TREX teams

“…The system is operational analyzing real-time data on a new generation of rovers for future planetary missions, as well as identifying materials using an imaging spectrometer on the International Space Station. …”
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Cohort profile: the Viral load Cohort North-East Lesotho (VICONEL) from 2016 to 2023 – cohort description, test volumes, predictors of viraemia and the road ahead by Tracy Glass, Frédérique Chammartin, Jochen Ehmer, Thomas Klimkait, Alain Amstutz, Josephine Muhairwe, Irene Ayakaka, Blaise Lukau, Jennifer Anne Brown, Lipontso Motaboli, Malebanye Lerotholi, Maurus Kohler, Kathrin Haenggi, Moliehi Mokete, Makobefo Gladys Chakela, Mpho Kao, Mathebe Kopo, Moleboheng Mokebe, Lorena Urda, Bienvenu Lengo Nsakala, Anna Klicpera, Nadine Tschumi, Niklaus Daniel Labhardt

“…Sex, age category/ART regimen core agent (combined variable), time since ART initiation and district were independently associated with viraemia.Future plans VICONEL offers potential for (1) further digitalisation and automation of results sharing at the client, facility and district/national level, (2) integration of additional clinical and diagnostic data, including comorbidities and drug resistance and (3) embedding randomised trials.…”
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Feasibility and safety evaluation of ultra-remote robot-assisted laparoscopic hysterectomy by Juyuan Huang, Li'an Li, Jing Cheng, Jing Liao, Yurou Chen, Yi Peng, Sha Wang, Qiongyan Zou, Guoyan Zhao, Wei Zhao, Mengya You, Jingying Yang, Yan Xiong, Kunxian Zhang, Chang Chen, Jiaqiang Xiong, Haotong Guan, Renjie Liu, Peng Zhou, Wuyi Zhao, Yangyang Dong, Xiuli Sun, Sichen Liang, Wei Zhang, Jianliu Wang, Yuanguang Meng

“…Remote robotic surgery is expected to be widely promoted in the future, providing services to patients in areas with limited medical resources.…”
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The association of physical activity and carotid intima-media-thickness in adolescents—data of the prospective early vascular ageing-tyrol cohort study by Bernhard Winder, Bernhard Winder, Bernhard Winder, Sophia J. Kiechl, Sophia J. Kiechl, Benoît Bernar, Benoît Bernar, Nina Gande, Anna Staudt, Anna K. Stock, Anna K. Stock, Christoph Hochmayr, Ralf Geiger, Andrea Griesmacher, Stefan Kiechl, Stefan Kiechl, Ursula Kiechl-Kohlendorfer, Michael Knoflach, Michael Knoflach, the Early Vascular Ageing (EVA)-Tyrol Study Group, Carmen Reiter, Christina Schreiner Julia Klingenschmid, Julia Marxer, Martina Kothmayer, Maximilian Pircher, Manuela Bock-Bartl, Mandy Asare, Maximilian Bohl, Raimund Pechlaner

“…However, previous research has shown that high PA is associated with an increased carotid intima-media-thickness (cIMT), an independent predictor for future cardiovascular disease. Our aim was to further investigate this unexpected association with two different measurement methods of PA and two established markers for Early Vascular Ageing: cIMT and carotid-femoral pulse-wave velocity (cfPWV).MethodsThe community-based Early Vascular Ageing-Tyrol cohort study included adolescents in western Austria and northern Italy. …”
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Harnessing Big Heterogeneous Data to Evaluate the Potential Impact of HIV Responses Among Key Populations in Sub-Saharan Africa: Protocol for the Boloka Data Repository Initiative by Refilwe Nancy Phaswana Mafuya, Edith Phalane, Amrita Rao, Kalai Willis, Katherine Rucinski, K Alida Voet, Amal Abdulrahman, Claris Siyamayambo, Betty Sebati, Mohlago Seloka, Musa Jaiteh, Lerato Lucia Olifant, Katharine Journeay, Haley Sisel, Xiaoming Li, Bankole Olatosi, Neset Hikmet, Prashant Duhoon, Francois Wolmarans, Yegnanew A Shiferaw, Lifutso Motsieloa, Mashudu Rampilo, Stefan Baral

“…Furthermore, it will inform future research directions and become an incredible institutional mechanism for epidemiological and public health training in South Africa and Sub-Saharan Africa. …”
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Mapping the Distribution and Population Status of <i>Alosa immaculata</i> and <i>Alosa tanaica</i> (Teleostei, Clupeidae) in the Bulgarian Black Sea Area by Desislava Rozdina, Yana Stoyanova, Georgi Terziyski, Slavi Studenkov, Boris Karakushev, Venceslav Delov, Konstantin Mihaylov, Dimitar Kozhuharov, Yordan Kutsarov, Nikolay Kolev, Nikolay Nedyalkov, Nikolay Natchev

“…The results of this study should be used to develop management plans for marine protected areas, and future monitoring projects should follow the sampling protocol.…”
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Causal role of plasma liposome in diabetic retinopathy: mendelian randomization (MR) study by Kai Yin, Lu Ding, Xueyan Li, Yuqi Zhang, Siyu Song, Liyuan Cao, Ruixue Deng, Min Li, Zirui Li, Qinjing Xia, Daqing Zhao, Xiangyan Li, Zeyu Wang

“…These findings may provide valuable insights into the causal relationships between lipid levels and DR, potentially informing future prevention and treatment strategies.…”
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Utilizing wastewater surveillance to model behavioural responses and prevent healthcare overload during “Disease X” outbreaks by Wenxiu Chen, Wei An, Chen Wang, Qun Gao, Chunzhen Wang, Lan Zhang, Xiao Zhang, Song Tang, Jianxin Zhang, Lixin Yu, Peng Wang, Dan Gao, Zhe Wang, Wenhui Gao, Zhe Tian, Yu Zhang, Wai-yin Ng, Tong Zhang, Ho-kwong Chui, Jianying Hu, Min Yang

“…Additionally, this approach can be applied to managing future outbreaks of unknown viruses or “Disease X”.…”
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RETRACTED ARTICLE: Extracorporeal membrane oxygenation support for SARS-CoV-2: a multi-centered, prospective, observational study in critically ill 92 patients in Saudi Arabia by Saad Alhumaid, Abbas Al Mutair, Header A. Alghazal, Ali J. Alhaddad, Hassan Al-Helal, Sadiq A. Al Salman, Jalal Alali, Sana Almahmoud, Zulfa M. Alhejy, Ahmad A. Albagshi, Javed Muhammad, Amjad Khan, Tarek Sulaiman, Maha Al-Mozaini, Kuldeep Dhama, Jaffar A. Al-Tawfiq, Ali A. Rabaan

“…However, these findings need to be carefully interpreted, as most of our cohort patients were relatively old and had multiple severe comorbidities. Future randomized trials, although challenging to conduct, are highly needed to confirm or dispute reported observations.…”
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Auditory confounds can drive online effects of transcranial ultrasonic stimulation in humans by Benjamin R Kop, Yazan Shamli Oghli, Talyta C Grippe, Tulika Nandi, Judith Lefkes, Sjoerd W Meijer, Soha Farboud, Marwan Engels, Michelle Hamani, Melissa Null, Angela Radetz, Umair Hassan, Ghazaleh Darmani, Andrey Chetverikov, Hanneke EM den Ouden, Til Ole Bergmann, Robert Chen, Lennart Verhagen

“…Furthermore, rigorous experimental design via (in)active control conditions is required to make substantiated claims in future TUS studies. Only when direct effects are disentangled from those driven by peripheral confounds can TUS fully realize its potential for research and clinical applications.…”
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Prevalence and temporal trends in myopia and high myopia children in China: a systematic review and meta-analysis with projections from 2020 to 2050Research in context by Wei Pan, Seang-Mei Saw, Tien Yin Wong, Ian Morgan, Zhikuan Yang, Weizhong Lan

“…New strategies for the prevention and control of myopia are now available, and understanding the prevalence and future trends in myopia and high myopia in children and adolescents in China may provide insights into the impact of implementing these measures. …”
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Small Extracellular Vesicles from Young Healthy Human Plasma Inhibit Cardiac Fibrosis After Myocardial Infarction via miR-664a-3p Targeting SMAD4 by Wang W, Li Y, Zhang C, Zhou H, Li C, Cheng R, Chen X, Pu Y, Chen Y

“…Considering the ease of obtaining plasma-derived sEVs, our study offers a promising therapeutic strategy for heart failure, with the potential for rapid clinical translation in the near future. Keywords: extracellular vesicles, young human plasma, cardiac fibrosis, MiR-664a-3p, SMAD4…”
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Safety of influenza vaccination during pregnancy: a systematic review by Brian Hutton, David Moher, Danielle B Rice, Claire Butler, Andrea C Tricco, Becky Skidmore, Candyce Hamel, Chantelle Garritty, Paul A Khan, Marco Ghassemi, Charlene Soobiah, Leila Esmaeilisaraji, Dianna M Wolfe, Deshayne Fell, Mona Hersi, Nadera Ahmadzai, Alan Michaud, Angela Sinilaite

“…Appropriate control of confounding and temporal biases in future studies would improve the evidence base.…”
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Geopolitical (non) opportunities vs. "late" response of the foreign political service of North Macedonia in the process of European integration by Jelisavac-Trošić Sanja, Arnaudov Mitko

“…However, the consequences for North Macedonia itself remained and only in the following period did the circumstances worsen and lead this country to a longer and more difficult path to accession. The future policy should be based on strong tactical tools, which are sufficiently flexible in relation to regional and international trends. …”
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