Enhancement of CD8+T cell cytotoxicity activity by IFN-α implies alternative pathologic role in systemic lupus erythematosus by Chen-xing Zhang, You-ying Mao, Yu-pin Tan, Mei-yu Zhang, Kang Shao, Shu-jun Wang, Ping Ji, Jia-yuan Wang, Lei Yin, Ying Wang

“…Relevant molecules and mechanism remains to be explored in the future.…”
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Positive associations between mean ambient temperature and involuntary admissions to psychiatric facilities by Noah L. Joore, Marte Z. van der Horst, Eric O. Noorthoorn, Jurriaan F.M. Strous, Fleur J. Vruwink, Sinan Guloksuz, Peter C. Siegmund, Jurjen J. Luykx

“…Our findings set the stage for further epidemiological and mechanistic studies into this topic, as well as for modeling studies examining future involuntary psychiatric admissions. …”
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Exploring dental students' knowledge on oral cancer prevention: a cross-sectional study in Moldova, Armenia, and Belarus by Olga Golburean, Diana Uncuta, Gayane Manrikyan, Natalia Shakavets, Izabella Vardanyan, Marina Markaryan, Ferda Özkaya, Daniela-Elena Costea, Tarig Al-Hadi Osman

“…By providing comprehensive education on risk factors and addressing personal habits, dental schools can better prepare future professionals to play a critical role in OC prevention and management.…”
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The effects of maternal health literacy, family functioning and self-efficacy on antepartum depression in pregnant women in China: a moderated mediation model by Ling Zhang, Li Ren, Hongyu Li, Haiyan Qiu, Hong Yang, Xiaolan Shi, Honghui Rong, Chuanfen Zheng, Fengju Li, Ting Luo, Lu Lu, Enyu Lei, Dali Yi, Ji-an Chen

“…MHL and FF can directly affect AD and mediate AD through SE. Future programs should consider MHL promotion, FF improvement and SE strengthening as breakthrough points when planning educational programs.…”
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Advancements in Nanotechnology for Enhanced Food Safety and Hygiene: Pathogen Detection, Smart Packaging, and Preservation Applications by Farhang Hameed Awlqadr, Ammar B. Altemimi, Qausar Hamed AlKaisy, Syamand Ahmed Qadir, Aryan Mahmood Faraj, Tablo Azad H.Slih, Rawaa H. Tlay, Tarek Gamal Mohamed Abd El-Maksoud, Franscesco Cacciola

“…By integrating cutting-edge detection methods, improving packaging solutions, and addressing safety and sustainability challenges, nanotechnology has the potential to transform food safety and hygiene practices. Future research should focus on advancing nanosensor sensitivity, developing sustainable materials, and fostering consumer trust through transparency and education, ensuring a safer and more sustainable food supply chain. …”
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Cutting-edge Bioinformatics strategies for synthesizing Cyclotriazadisulfonamide (CADA) analogs in next-Generation HIV therapies by Jay Gabriel B. Larga, Wrynan T. Munabirul, Abu Tayab Moin, Md Maisum Sarwar Jyoti, Mst Sanjida Nasrin, Minhaz Abdullah Al Mueid, Abdul Ahad, Anwar Parvez, Mst Sabrina Yeasmin, Rupali M. Barhate, Rajesh B. Patil, Margel C. Bonifacio

“…Synthetic routes for these four analogs were proposed for future studies. The results of this study offer a new perspective on developing drugs to inhibit HIV entry.…”
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Prognostic significance of p27 in colorectal cancer: a meta-analysis and bioinformatics analysis by Jing Zou, Dong Wang, Gaoping Yin, Kexiang Lu, Kaibin Chang, He Li

“…The findings from the HPA indicated that there was lower expression of p27 in tumor tissues compared with normal tissues.ConclusionAlthough inconsistent results were reached with the bioinformatics analysis from this meta-analysis, it was confirmed that a low expression of p27 can adversely affect the prognosis of patients with CRC and make a meaningful impact on a part of the clinicopathological features in the meta-analysis with abundant data. In the future, predicting the prognosis of patients with CRC and guiding treatment might emerge as a significant objective.…”
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Analytical Accuracy of a Continuous Glucose Monitor in Adult Diabetic KetoacidosisTake-Home Points by Nathan L. Haas, MD, Lynn Ang, MD, Nazanene H. Esfandiari, MD, Ahsan M. Khan, MBBS, James A. Cranford, PhD, Ashley Cohen, MD, Jordan Sell, MD, Mostafa Abdel-Hamid, MD, Kevin E. Romanchik, BSN, RN, Frederick K. Korley, MD, PhD

“…Interpretation: In this study, CGM provided accurate measurements of blood glucose and identified missed opportunities for earlier intervention in adults with DKA. Future interventional trials can assess the impact of CGM-guided DKA management on patient outcomes, patient experience, and resource use.…”
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Water, Sanitation and Hygiene in a Conflict Area: A Cross-Sectional Study in South Kordofan, Sudan by Rofida Asmally, Abdelmalik A. Imam, Abdullatif Eissa, Abubakr Saeed, Ahmed Mohamed, Eahaa Abdalla, Mariam Alazraa M. Esmaeel, Mariam Elbashir, Mohamed H. Elbadawi, Mohammed Omer, Raghad Eltayeb, Ranya Mohammed, Tibyan Abdalhamed, Tina Merghani

“…It also sought to identify factors affecting community satisfaction with WASH services and to establish a data-driven basis for future interventions addressing these issues. Methods A cross-sectional study accompanied a medical mission to South Kordofan, selecting 33 villages from South Kordofan based on healthcare, population, and accessibility. …”
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Use of Augmented Reality for Training Assistance in Laparoscopic Surgery: Scoping Literature Review by Francisco Javier Celdrán, Javier Jiménez-Ruescas, Carlos Lobato, Lucía Salazar, Juan Alberto Sánchez-Margallo, Francisco M Sánchez-Margallo, Pascual González

“…Moreover, the need for standardized evaluation metrics is emphasized, paving the way for future research into AR’s full potential in laparoscopic skill acquisition.…”
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An Explainable Artificial Intelligence Text Classifier for Suicidality Prediction in Youth Crisis Text Line Users: Development and Validation Study by Julia Thomas, Antonia Lucht, Jacob Segler, Richard Wundrack, Marcel Miché, Roselind Lieb, Lars Kuchinke, Gunther Meinlschmidt

“…Such models may potentially support clinical decision-making in suicide prevention services. Future research should explore multimodal input features and temporal aspects of suicide risk.…”
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The interplay between persistent pathogen infections with tumor microenvironment and immunotherapy in cancer by Si Chen, Caihong Yao, Na Tian, Chunying Zhang, Yuemei Chen, Xuting Wang, Yue Jiang, Tonghao Zhang, Tingting Zeng, Yali Song

“…Unraveling the underlying mechanisms can unveil potential targets for immunotherapy, improving our comprehension of the immune response to cancer and potentially leading to more effective cancer treatments in the future.…”
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Utilization of Blood Flow Restriction Therapy with a Former Triathlete After Total Knee Arthroplasty: A Case Report by Christopher Keating, Stephanie Muth, Cameron Hui, Lisa T Hoglund

“…The purpose of this case report is to describe the impact of BFR use in an individual after TKA, employing pain measurements, quantitative sensory testing, patient-reported outcome measures, physical performance tests, and muscle strength and power testing to explore potential treatment effects and identify potential predictors of response for future studies. # Case Description A 49-year-old former female triathlete with a history of knee injury and arthroscopic surgery underwent a right TKA and sought physical therapy (PT) due to pain, limited range of motion (ROM), and knee instability during weight bearing activity. …”
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Implementing a General Practice-Based Link Worker Intervention for People with Multimorbidity During the Covid-19 Pandemic- a Mixed Methods Process Evaluation of the LinkMM RCT by Bridget Kiely, Ivana Keenan, Sonali Loomba, Natalie Mack, Vivienne Byers, Emer Galvin, Muireann O’Shea, Patrick O’Donnell, Fiona Boland, Barbara Clyne, Eamon O’Shea, Susan M. Smith, Deirdre Connolly

“…Timing of the referral, location within general practice and link workers’ person-centred approach facilitated the intervention. Conclusions: For future evaluations, recruitment procedures need to be simplified and integrated into everyday practice. …”
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Health Economic Evaluation of Patients With Colorectal Liver Metastases Randomized to ALPPS or TSH: Analysis From the LIGRO Trial by Kristina Hasselgren, MD, PhD, Martin Henriksson, PhD, Bård I. Røsok, MD, PhD, Peter N. Larsen, MD, PhD, Ernesto Sparrelid, MD, PhD, Gert Lindell, MD, PhD, Nicolai A. Schultz, MD, PhD, Bjorn A. Bjørnbeth, MD, PhD, Bengt Isaksson, MD, PhD, Magnus Rizell, MD, PhD, Anna Lindhoff Larsson, RN, Per Sandström, MD, PhD, Bergthor Björnsson, MD, PhD

“…One hundred patients with colorectal liver metastases (CRLM) and standardized future liver remnant <30% were randomized to associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) or two-staged hepatectomy (TSH). …”
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Training for Sustainable and Healthy Building for 2050: New Methodologies for an Integrated and Transnational Education Approach Targeting Skills Development for the Transition Tow... by Maria K. Koukou, Susana Lucas, Julia Justino, Silviano Rafael, Antonios D. Livieratos, Nelson Carriço, John Konstantaras, Michail Gr. Vrachopoulos, Anna Chiara Benedetti, Cecilia Mazzoli, Annarita Ferrante, Mohammad Abdollah Fadel Abdollah, Rossano Scoccia, Jacopo Famiglietti, Tomasz Bakoń, Joanna Aleksiejuk-Gawron

“…However, based on the feedback of students and teachers, some improvements for future editions of the courses are required.…”
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CHI study: protocol for an observational cohort study on ageing and mental health in community-dwelling older adults by Lei Feng, Lieng Hsi Ling, Qiushi Feng, Rachael Zhi Yi Lee, Junhong Yu, Iris Rawtaer, Patrick Finbarr Allen, Zhiming Bao, Jeong Kyu Lee, Chin Tat Lim, Leng Leng Thang, Thet Naing, D Y Wang, Kai Zhen Yap, EH Kua, Rathi Mahendran

“…Results from the cohort will enable future studies to identify at-risk groups and develop interventions to improve the physical and mental health and quality of life of older adults.Ethics and dissemination Approval of the cohort study by the National University of Singapore Institutional Review Board (NUS-IRB Reference code: H-17-047) was obtained on 12 October 2017. …”
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Frictional heat-assisted performance enhancement in dynamic Schottky contact of Al/Ag2Se-based tribovoltaic nanogenerator by Supakarn Worathat, Utchawadee Pharino, Phakkhananan Pakawanit, Arunothai Rattanachata, Rangson Muanghlua, Sugato Hajra, Hoe Joon Kim, Saichon Sriphan, Naratip Vittayakorn

“…The concepts given in this study establish the basis for the progress of effective energy collection employing semiconducting materials and the advancement of flexible harvesting and sensing device development in the future.…”
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Peningkatan Akurasi Metode Weighted Fuzzy Time Series Forecasting Menggunakan Algoritma Evolusi Differensial dan Fuzzy C-Means by Agus Fachrur Rozy, Solimun Solimun, Ni Wayan Surya Wardhani

“…Abstract Prediction is a form of approach in anticipating future uncertainties. Conventional prediction methods encounter difficulties in adapting data with the assumptions used, necessitating the application of the Weighted Fuzzy Time Series (WFTS) method. …”
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Do continuous glucose monitoring (CGM) metrics predict macrovascular and microvascular complications in diabetes? The FACULTY protocol of a retrospective real-world cohort study by Eric Vicaut, Ramzi A Ajjan, J Seufert, Gérard de Pouvourville, Emmanuel Cosson, Laure Carcaillon-Bentata, Tadej Battelino, Patrick Blin, Fleur Levrat-Guillen, Michael Joubert

“…Continuous glucose monitoring (CGM)-derived glucose metrics provide a more comprehensive assessment of glycaemia, but their role in predicting future vascular complications remains unclear. Here, we present the protocol for a real-world cohort study, aiming to establish the relationship between CGM-derived glycaemic metrics and the incidence of macrovascular and/or microvascular complications in people with diabetes.Methods and analysis This cohort study will use data from all CGM new users (FreeStyle Libre system) in France who uploaded their glycaemic values onto the LibreView cloud-based system, linked with data from the French nationwide Système National des Données de Santé claims database. …”
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