Cancer as an Embryological Phenomenon and Its Developmental Pathways: A Hypothesis regarding the Contribution of the Noncanonical Wnt Pathway by Jaime Cofre, Kay Saalfeld, Eliana Abdelhay

“…The striking similarities in the processes of cancer and gastrulation have prompted speculation regarding the developmental pathways involved in their regulation. One of the fundamental requirements for the developmental pathways in gastrulation and cancer is the ability to respond to environmental stimuli, and it has been proposed that the Kaiso and noncanonical Wnt pathways participate in the mechanisms regulating these developmental pathways. …”
Get full text

microRNAs as a New Mechanism Regulating Adipose Tissue Inflammation in Obesity and as a Novel Therapeutic Strategy in the Metabolic Syndrome by Qian Ge, Sonia Brichard, Xu Yi, QiFu Li

“…It is well known that obesity-induced chronic inflammation plays a fundamental role in the pathogenesis of MS. White adipose tissue (AT) is the primary site for the initiation and exacerbation of obesity-associated inflammation. …”
Get full text

A Case of Congenitally Corrected Transposition of the Great Arteries Discovered on Coronary Computed Tomography by Adam T. Marler, Jennifer N. Slim, Travis Batts, James Watts, Ahmad M. Slim

“…Congenitally corrected transposition of the great arteries is a rare condition accounting for less than 1% of all congenital cardiac diseases. The fundamental nature of this condition involves a blend of atrioventricular as well as ventriculoarterial discordance. …”
Get full text

A theoretical context for (θ,β)-convexity and (θ,β)-concavity with hypersoft settings by Atiqe Ur Rahman

“…This paper examines the traditional concepts of -convex and -concave sets in a hypersoft set context, discussing their fundamental inclusive features and set-theoretic operations. …”
Get full text

CHANGES TO RETAIL BUSINESS MODELS - OVERVIEW OF THE DETERMINING FACTORS by Maria Sławińska

“…This paper outlines the essence and fundamental components of retail business models, indicates the probable directions in which those models may evolve and identifies the determining factors and trends that shape the business models applied by retailers. …”
Get full text

Alunos analisando suas próprias soluções: Adição de frações by Rafael Filipe Novoa Vaz, Lilian Nasser, Elizabeth Belfort

“…O experimento foi desenvolvido em escola pública no Estado do Rio de Janeiro, como parte  da  revisão  de  frações usualmente realizada  no  sétimo  ano  do Ensino  Fundamental.  São apresentadas resoluções desenvolvidas por  alunos,  quando  solicitados a  analisar soluções para questões relativas à adição e subtração de frações desenvolvidas por seus colegas. …”
Get full text

Coronavirus pandemic: yesterday, today, tomorrow of the Russian economy by O. M. Makhalina, V. N. Makhalin, A. B. Yaroshchuk

“…In conclusion, the main challenges and risks in the implementation of the “National Action Plan” are formulated, which provides both an increase in employment, an increase in citizens’ incomes, the restoration of economic growth and a fundamental changes in the structure of the economy.…”
Get full text

AS MÃOS QUE EMBALAM O BERÇO: um estudo sobre redes informais de apoio à maternidade by Sílvia Portugal

“…Sublinhando a importância fundamental das solidariedades femininas, conclui-se pelo papel fulcral do "parentesco restrito" e pela fone matrilinearidade das redes de apoio. …”
Get full text

Reclassificando o DF by João Phillip Tilopa Barbosa de Oliveira Neuen

“…Para tanto, o conceito de “vazio” é fundamental, já que se mostra como ferramenta estratégica para a organização e a classificação do espaço urbano nesta localidade. …”
Get full text

The Anthropocene is shifting the paradigm of geosciences and science by Coudrain, Anne, Le Duff, Matthieu, Mitja, Danielle

“…Noting that humans are affecting the Earth’s envelopes, with geosciences becoming inseparable from social sciences and humanities, and acknowledging the increasing use of the word Anthropocene, the authors of this paper explore the possibility of a scientific paradigm shift. (1) Since the 17th century, modern science has developed in a context of naturalist worlding that favors its hegemony over other modes of existence and its paradigm of a quest to define the laws of nature. (2) Various manifestations attest to the emergence of a paradigm of knowledge diversity and the unravelling of the naturalist worlding. (3) The current boom in participatory science is a sign of this paradigm shift: through the fundamental changes to the Earth System that refer to it, the Anthropocene forces science to move towards action and interact with a society involved in adapting to changes and concerned with the threats to its territory’s habitability.…”
Get full text

The relationship of spatial visualization ability and number representation: evidence from multiple tasks by Mengxia Li, Yuning Chen, Jiahui Yang, Qiangqiang Wang, Xiaolin Ye

“…These findings are consistent with the view that spatial visualization is recognized for its potential to enhance numerical skills, encompassing competencies associated with fundamental number. Therefore, developing children’s spatial visualization ability may be an effective way to enhance their number representation skills. …”
Get full text

Investigations on Shaped Mirror Systems in Quasi-Optical Mode Converters Based on Irradiance Moments Method by Hai Wang, Zejian Lu, Xiaoming Liu, Junsheng Yu, Yuan Yao, Xiaodong Chen, Limei Qi, Zhijiao Chen

“…A method of transforming high-order Gaussian beams (GBs) mode into circular symmetry fundamental Gaussian beam (FGB) mode with arbitrary waist size is presented using irradiance moments method in quasi-optical (QO) mode converters. …”
Get full text

Rights of nature and the indigenous Peoples in Bolivia and Ecuador: a Straitjacket for Progressive development Politics? by Rickard LALANDER

“…The Indigenous concept of Sumak Kawsay on human beings living in harmony with each other and the environment is the fundamental framing of the new constitutions of Ecuador and Bolivia. …”
Get full text

Pepper Production in Miami-Dade County, Florida by Qingren Wang, Shouan Zhang, Yuncong Li, Dakshina R. Seal, Waldemar Klassen, Teresa Olczyk

“…This revised 7-page fact sheet provides general information and guidelines for pepper growers in Miami-Dade County, including major pepper varieties, and their horticultural traits, and fundamental soil and water management requirements. …”
Get full text

Connectivity Index in Vague Graphs with Application in Construction by Huiqin Jiang, Yongsheng Rao

“…Connectivity index (CI) in graphs is a fundamental issue in fuzzy graph theory that has wide applications in the real world. …”
Get full text

2003 Handbook of Employment Regulations Affecting Florida Farm Employers and Workers: Introduction by Leo C. Polopolus, Michael T. Olexa, Fritz Roka, Carol Fountain

“…Its purpose is simply to focus employers and employees on the fundamental provisions of the laws which govern their relationships. …”
Get full text

High-Field Growth of Semiconducting Anodic Oxide Films on Metal Surfaces for Photocatalytic Application by Ronald Vargas, David Carvajal, Brunella Galavis, Alberto Maimone, Lorean Madriz, Benjamín R. Scharifker

“…We discuss the scope and mechanisms for anodic oxide growth, describing the development of kinetic models and the correlations between theory and kinetic data, leading to fundamental information to characterize the primary processes occurring during the anodization of valve metals under high fields. …”
Get full text

Cultural heritage and energy transition – A lesson from the past by Xavier Casanovas, José A. Alonso Campanero, Tiziana Campisi

“… In the complex landscape of energy transition, Cultural Heritage emerges as a fundamental pillar of ‘innovability’, suggesting a lesson from the past. …”
Get full text

Micropenis by Jeremy Wiygul, Lane S. Palmer

“…Micropenis is part of a larger group of conditions broadly known as inconspicuous penis; however, it is fundamentally different from the other diagnoses in this group, such as webbed penis and buried penis, in that the underlying problem is the size of the penis itself, not with the surrounding and overlying skin. …”
Get full text

On the ethics of multilevel marketing based on dietary supplements by Edgar Manuel Cambaza, Filipe Francisco Gerente Gustavo, Sebastião Job Cuata, Rajabo Victorino Jamal

“…The conclusion highlights that as it currently operates, MLM does not meet fundamental ethical principles and requires significant adjustments. …”
Get full text