Melatonin as an Anti-Inflammatory Agent Modulating Inflammasome Activation by Gaia Favero, Lorenzo Franceschetti, Francesca Bonomini, Luigi Fabrizio Rodella, Rita Rezzani

“…Melatonin, an endogenous indoleamine, is considered an important multitasking molecule with fundamental clinical applications. It is involved in mood modulation, sexual behavior, vasomotor control, and immunomodulation and influences energy metabolism; moreover, it acts as an oncostatic and antiaging molecule. …”
Get full text

Incremental accumulation of linguistic context in artificial and biological neural networks by Refael Tikochinski, Ariel Goldstein, Yoav Meiri, Uri Hasson, Roi Reichart

“…Abstract Large Language Models (LLMs) have shown success in predicting neural signals associated with narrative processing, but their approach to integrating context over large timescales differs fundamentally from that of the human brain. In this study, we show how the brain, unlike LLMs that process large text windows in parallel, integrates short-term and long-term contextual information through an incremental mechanism. …”
Get full text

City, cholera, and COVID: A reading mediated by religiosity and science by Carlos E. Flores-Rodríguez, Luis Fajardo-Velázquez, Rosa María López-Nanco

“…On its way to liberalism and, above all, in relation to the difficulties that characterized this moment, the 19th century was fundamental in the configuration of the societies of Mexican cities and, in particular, of peripheral neighborhoods. …”
Get full text

A comprehensive survey of scoring functions for protein docking models by Azam Shirali, Vitalii Stebliankin, Ukesh Karki, Jimeng Shi, Prem Chapagain, Giri Narasimhan

“…Abstract Background While protein-protein docking is fundamental to our understanding of how proteins interact, scoring protein-protein complex conformations is a critical component of successful docking programs. …”
Get full text

Macroscopic perspective on phase transition behavior of natural single-crystal graphite under different pressure environments by Xiaoshuang Yin, Songyang Li, Lijuan Wang, Peiyuan Liu, Zhihai Cheng, Huiyang Gou, Liuxiang Yang

“…Comprehensive understanding of the direct transformation pathway from graphite to diamond under high temperature and high pressure has long been one of the fundamental goals in materials science. Despite considerable experimental and theoretical progress, current experimental studies have mainly focused on the local microstructural characterizations of recovered samples, which has certain limitations for high-temperature and high-pressure products, which often exhibit diversity. …”
Get full text

Proliferative Vitreoretinopathy after Eye Injuries: An Overexpression of Growth Factors and Cytokines Leading to a Retinal Keloid by Francesco Morescalchi, Sarah Duse, Elena Gambicorti, Mario R. Romano, Ciro Costagliola, Francesco Semeraro

“…This paper reviews the current literature and clinical trial data on the pathogenesis of PVR and its correlation with ocular trauma and describes the biochemical/molecular events that will be fundamental for the development of novel treatment strategies. …”
Get full text

Applications of ultrafast nano-spectroscopy and nano-imaging with tip-based microscopy by Zhichen Zhao, Vasily Kravtsov, Zerui Wang, Zhou Zhou, Linyuan Dou, Di Huang, Zhanshan Wang, Xinbin Cheng, Markus B. Raschke, Tao Jiang

“…Abstract Innovation in microscopy has often been critical in advancing both fundamental science and technological progress. Notably, the evolution of ultrafast near-field optical nano-spectroscopy and nano-imaging has unlocked the ability to image at spatial scales from nanometers to ångströms and temporal scales from nanoseconds to femtoseconds. …”
Get full text

Training of Competitive Graduates Based on the Educational Standard of the ITMO University by A. A. Shekhonin, A. O. Voznesenskaya, A. V. Bakholdin, O. A. Gavrilina

“…The authors propose the design and implementation system of the educational programs based on integration of the fundamental classical technical education, enhanced development of the universal, common and professional competencies, and extended implementation of the modern theoretical and applied practice-oriented researches, which are supported an active participation of industrial companies and research organizations in educational activities. …”
Get full text

Criatividade infantil: um estudo sobre o ponto de vista da própria criança by Rayanne Linhares Azevedo, Regina Lúcia Sucupira Pedroza, Asdrúbal Borges Formiga Sobrinho

“…Participaram do estudo 30 crianças, com idade entre 6 e 7 anos, do 1º ano do Ensino Fundamental I, em uma escola com metodologia montessoriana, fator ambiental capaz de influenciar a criatividade infantil. …”
Get full text

A comparison of the alterations of oral microbiome with fixed orthodontic therapy and clear aligners: a systematic review by Alessandra Lucchese, Marta Marcolina, Nicasio Mancini, Roberto Ferrarese, Serena Acconciaioco, Enrico Gherlone, Chiara Bonini, Maurizio Manuelli, Antonella Polimeni

“…Aim The oral microbiome plays a fundamental role in maintaining homeostasis of the oral cavity. …”
Get full text

O que Dizem as Diretrizes Curriculares Nacionais de Formação de Professores sobre o Desenvolvimento Profissional Docente no Brasil by Clenya Ruth Alves Vasconcelos, Solange Helena Ximenes Rocha

“…Nesse contexto, sublinhamos a abordagem colaborativa como uma estratégia fundamental para o Desenvolvimento Profissional Docente. …”
Get full text

Scientific challenges faced by Mn‐based layered oxide cathodes with anionic redox for sodium‐ion batteries by Chao Zheng, Shengnan He, Jiantuo Gan, Zhijun Wu, Liaona She, Yong Gao, YaXiong Yang, Jiatao Lou, Zhijin Ju, Hongge Pan

“…Finally, this review provides new insights for future direction, encompassing both fundamental research, such as novel cathode types, interface optimization, and interdisciplinary research, and considerations from an industrialization perspective, including scalability, stability, and safety.…”
Get full text

Bone Regeneration: Mini-Review and Appealing Perspectives by Sylvain Le Grill, Fabien Brouillet, Christophe Drouet

“…In this mini-review, the fundamentals of bone healing materials and clinical challenges are summarized and commented on with regard to progressing scientific discoveries. …”
Get full text

Beyond Crisis Talk: Making Time for Re-Searching New Narratives of Human Relations With Soil by Rita Giuffredi, Christian Colella, Laura Colucci-Gray, Andrea Caretto, Raffaella Spagna, Alba L'Astorina

“…Findings point to the need to address the fundamental questions that such an approach poses for all research communities. …”
Get full text

Deformation of socio-ecological and economic space and interterritorial cooperation in modern conditions by R. F. Gataullin, E. R. Chuvashaeva

“…Moreover, this activity can be aimed at creating a fundamentally new space architecture or improving its elements.…”
Get full text

Estimation of Sine Inverse Exponential Model under Censored Schemes by M. Shrahili, I. Elbatal, Waleed Almutiry, Mohammed Elgarhy

“…We investigated some fundamental statistical properties such as quantile function (QFu), moments (Mo), moment generating function (MGFu), incomplete moments (ICMo), conditional moments (CMo), and the SIE distribution parameters were estimated using the maximum likelihood (ML) method for estimation under censored samples (CS). …”
Get full text

One-step solvothermal preparation of Fe-doped Ni0.85Se/NF: An efficient catalyst for the oxygen evolution reaction by Longqi Zhu, Runze Wang, Chen Wang, Shuhan Yang, Haizhen Liu, Bo Xing, Honghui Cheng, Kuikui Wang

“…Metal–cation doping is a fundamental strategy for enhancing catalyst performance. …”
Get full text

Altered Autophagy-Associated Genes Expression in T Cells of Oral Lichen Planus Correlated with Clinical Features by Ya-Qin Tan, Jing Zhang, Ge-Fei Du, Rui Lu, Guan-Ying Chen, Gang Zhou

“…Autophagy has emerged as a fundamental trafficking event in mediating T cell response, which plays crucial roles in innate and adaptive immunity. …”
Get full text

Scanless laser waveform measurement in the near-infrared by Tran-Chau Truong, Yangyang Liu, Dipendra Khatri, Yuxuan Zhang, Bonggu Shim, Michael Chini

“…Here, we demonstrate an all-optical sampling technique for near-infrared laser fields, wherein an intense fundamental field generates a sub-cycle gate through nonlinear excitation of a wide-bandgap crystal, in this case, ZnO, which can sample the electric field of a weak perturbing pulse. …”
Get full text

Effect of aluminizing coating on fatigue properties of DD6 single crystal superalloy by DONG Jianmin, LI Jiarong, ZHEN Zhen, XU Zhenhua

“…The coupling effect of surface roughness， oxidation damage， and element interdiffusion is the fundamental reason for the difference in fatigue life between uncoated and coated samples.…”
Get full text