Anti-diabetic effect of aloin via JNK-IRS1/PI3K pathways and regulation of gut microbiota by Ruting Zhong, Lanbin Chen, Yuanyuan Liu, Shouxia Xie, Sumei Li, Bin Liu, Chao Zhao

“…Thus, aloin ameliorated IR via activating IRS1/PI3K/Akt signaling pathway and regulating the gut microbiota, and it may be promising candidate as functional food for diabetic therapy.…”
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Principles of Rational Nutrition for Managing Constipation by Yu. O. Shulpekova, D. A. Sheptulin, N. V. Shulpekova

“…For the prevention and management of constipation, functional food products enriched with oligo-, polysaccharides and probiotics are developed. …”
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Ameliorative Effects of Polygonatum kingianum Polysaccharides on Lipid Metabolism Disorders and Brain Function Impairments in Obese Mice by XU Yuncong, YAN Qiaojuan, ZHU Chunhua, YANG Shaoqing, LI Houjiang, JIANG Zhengqiang

“…PKP mitigate obesity-induced lipid disorders and brain damages, indicating their potential as a functional food ingredient for obesity and suppressing obesity-induced brain damage.…”
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Quality Evaluation of Herbal Yoghurt Produced Using Cinnamon (Cinnamon cassia), Garlic (Allium sativum) and Ginger (Zingiber officinale) by Ifeoma Elizabeth Mbaeyi-Nwaoha, Augustina Chinechendu Uzoigwe, Helen Onyeaka

“…From the results obtained, herbal yoghurt can serve as a highly nutritional functional food enriched with a variety of health benefits.…”
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Stevenleaf from Gynostemma Pentaphyllum inhibits human hepatoma cell (HepG2) through cell cycle arrest and apoptotic induction by Sayed Sajid Hussain, Fan Zhang, Yuanyuan Zhang, Kiran Thakur, Mahrukh Naudhani, Carlos L. Cespedes-Acuña, Zhaojun Wei

“…The mechanistic explanation for the anticancer activity of SV as functional food can be derived from above results.…”
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Drying kinetic models, thermodynamics, physicochemical qualities, and bioactive compounds of avocado (Persea americana Mill. Hass variety) seeds dried using various drying methods by Desta Dugassa Fufa, Tilahun Bekele, Aynadis Tamene, Geremew Bultosa

“…Avocado seeds can be used in many functional food and non-food applications, due to their nutritional and health-promoting properties. …”
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Development of Nutrient-Rich Injera Using Amaranthus Leaf/Grain and Teff Flours: A Study on Nutritional Value, Sensory Characteristics, and Storage Stability by Betelhem Abera, Ramesh Duraisamy, Tewodros Birhanu, Beyene Gurbo, Ketemaw Salelign

“…It has substantial national and global recognition due to its nutraceutical benefits and its gluten-free nature. Flatbread, a functional food for health promotion, can be enhanced with less mineral-rich crops like Amaranthus, which are often underutilized, to increase its nutritional and mineral content. …”
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Supercritical Extraction and Compound Profiling of Diverse Edible Mushroom Species by Slađana Krivošija, Nataša Nastić, Milica Karadžić Banjac, Strahinja Kovačević, Sanja Podunavac-Kuzmanović, Senka Vidović

“…Mushrooms are a raw material rich in many nutritional compounds, and that is why a number of them are widely known as functional food. They contain fatty acids, carbohydrates, lycopene, sterols, lovastatin, trace elements, and other valuable compounds that show a wide range of properties, such as hepatoprotective, anticancer, antiviral, etc. …”
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Caffeic Acid Phenethyl Ester Regulates PPAR’s Levels in Stem Cells-Derived Adipocytes by Luca Vanella, Daniele Tibullo, Justyna Godos, Francesca Romana Pluchinotta, Claudia Di Giacomo, Valeria Sorrenti, Rosaria Acquaviva, Alessandra Russo, Giovanni Li Volti, Ignazio Barbagallo

“…As there is now substantial interest in functional food and nutraceutical products, the observed therapeutic value of Cape in insulin-resistance related diseases should be taken into consideration.…”
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Immunomodulatory effects of fucoidan extracted from Sargassum fusiforme in RAW 264.7 macrophages by Serim Park, Yunjin Choi, Seonmi Ji, Seonghui Kim, Seon Yeong Ji, Yung Hyun Choi, You-Jin Jeon, Bomi Ryu, Jun-Geon Je, Suengmok Cho

“…These findings suggest that SFF exhibits potent immunomodulatory activity in the RAW 264.7 macrophage model and holds potential as a functional food to support immune health. …”
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Characterization of Nutritional Composition, Antioxidative Capacity, and Sensory Attributes of Seomae Mugwort, a Native Korean Variety of Artemisia argyi H. Lév. & Vaniot by Jae Kyeom Kim, Eui-Cheol Shin, Ho-Jeong Lim, Soo Jung Choi, Cho Rong Kim, Soo Hwan Suh, Chang-Ju Kim, Gwi Gun Park, Cheung-Seog Park, Hye Kyung Kim, Jong Hun Choi, Sang-Wook Song, Dong-Hoon Shin

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Andrias davidianus bone peptides alleviates hyperuricemia-induced kidney damage in vitro and in vivo by Wei Li, Haihong Chen, Hongliang Chen, Ziyin Li, Wei Hu, Qinxuan Zhou, Bing Xu, Yi Wang, Xinhui Xing

“…Hyperuricemia (HUA) is a vital risk factor for chronic kidney diseases (CKD) and development of functional foods capable of protecting CKD is of importance. …”
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Composition of Anthocyanins in Colored Grains and the Relationship of Their Non-Acylated and Acylated Derivatives by Sladjana Zilic, Dejan Dodig, Jelena Vancetovic, Nikola Grcic, Vesna Peric, Primoz Titan, Vuk Maksimovic

“…Bearing in mind that cereals are widely grown crops, anthocyanins-rich colored grains could be used as a functional food ingredient that provide health benefits to a large part of human world's population. …”
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A randomized double-blind active-controlled clinical trial on the efficacy of topical basil (Ocimum basilicum) oil in knee osteoarthritis by Alireza Askari, Fatemeh Sadat Hasheminasab, Fatemeh Sadat Hasheminasab, Omid Sadeghpour, Mohammad Mehdi Naghizadehd, Seyed Ali Ravansalar, Aida Iraji, Mohammad Hashem Hashempur

“…BackgroundBasil is a widely used herb in Persian medicine and is gaining recognition as a functional food worldwide.Aim of the studyThis trial aimed to assess the effectiveness of a traditional formulation of basil oil in comparison with diclofenac gel in treating knee osteoarthritis, considering its established anti-inflammatory, anti-nociceptive, and anti-oxidative properties.Materials and methodsOne hundred eligible patients were equally randomized to the traditional basil oil (containing sesame oil) and diclofenac gel groups. …”
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Klanceng Honey (Tetragonula laeviceps): Its effect on fasting blood glucose, lipid and hematological profiles, and pancreatic histopathology of diabetic rats by Agussalim, Nafiatul Umami, Nurliyani, Wan Iryani Wan Ismail, Dewi Masyithoh, Ustadi, Ali Agus

“…T. laeviceps honey can potentially be used as a functional food for therapy of DM patients.…”
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Soluble fibres modulate dough rheology and gluten structure via hydrogen bond density and Flory-Huggins water interaction parameter by Stefano Renzetti, Lisa Lambertini, Helene C.M. Mocking-Bode, Ruud G.M. van der Sman

“…Soluble fibres are gaining increasing interest for functional food applications like bread, but their interaction with gluten and effects on dough rheology are not fully elucidated. …”
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Expressed Sequence Tags Analysis and Design of Simple Sequence Repeats Markers from a Full-Length cDNA Library in Perilla frutescens (L.) by Eun Soo Seong, Ji Hye Yoo, Jae Hoo Choi, Chang Heum Kim, Mi Ran Jeon, Byeong Ju Kang, Jae Geun Lee, Seon Kang Choi, Bimal Kumar Ghimire, Chang Yeon Yu

“…Perilla frutescens is valuable as a medicinal plant as well as a natural medicine and functional food. However, comparative genomics analyses of P. frutescens are limited due to a lack of gene annotations and characterization. …”
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3-Epi-betulinic acid 3-O-β-D-glucopyranoside (eBAG) induces autophagy by activation of AMP-activated protein kinase in hepatocellular carcinoma by Mengjie Liu, Xuqiang Liu, Kaiyue He, Yongping Jian, Yujia Li, Jinrong Guo, Jingyu Yang, Zhixiang Xu, Wenyi Kang

“…We further validated the anti-tumor effect of eBAG in the murine xenograft model of hepatocellular carcinoma and found that eBAG treatment promoted the induction of autophagy and reduction of tumor growth in mice. As a functional food ingredient, eBAG is a potential therapeutic agent for the treatment of hepatocellular carcinoma and esophageal cancer.…”
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A bibliometric review of functional ingredients and their efficacy in developing functional biscuits [version 3; peer review: 1 approved, 2 approved with reservations] by Kshama Vishwakarma, Varalakshmi Chandra Sekaran, Vidya Patwardhan, Asha Kamath

“…Similarly, present times have seen exponential growth in functional food in bakery product segments like breads and biscuits. …”
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Anti-obesity effects of fucoidan from Sargassum thunbergii in adipocytes and high fat diet induced obese mice through inhibiting adipogenic specific transcription factor by Hyo-Geun Lee, H.H.A.C.K. Jayawardhana, Fengqi Yang, D.P. Nagahawaththa, N.M. Liyanage, Kyung-Mo Song, Yun-Sang Choi, Seung-Hong Lee, You-Jin Jeon, Min-Cheol Kang

“…Together, these results indicate that STAC and purified STAF3 from Sargassum thunbergia is a potent source to develop as ananti-obesity agents or functional food products to counter obesity.…”
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