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Reengineering of business processes in the context of application of new organizational schemes of construction management
Published 2024-08-01“…The research is based on the postulates of cybernetics, the logistics of regulatory influences, the organization of production systems, and structural and functional analysis. The scientific background of the authors was used, which was reflected in their publications on this problem. …”
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163
The Model of PPARγ-Downregulated Signaling in Psoriasis
Published 2020-01-01“…We combined experimental results and network functional analysis to reconstruct the model of PPARγ-downregulated signaling in psoriasis. …”
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164
Discovery of Evolutionary Loss of the Ubiquitin-like Autophagy-Related ATG12 System in a Lineage of Apicomplexa
Published 2025-01-01“…However, our in vitro functional analysis using recombinant proteins demonstrated that ATG3 retained the ability to interact with ATG8 in <i>Babesia bovis</i>, a model species in piroplasmida. …”
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165
Microarray Gene Expression Analysis of Murine Tumor Heterogeneity Defined by Dynamic Contrast-Enhanced MRI
Published 2002-07-01“…Using DCE-MRI in a murine subcutaneous tumor model, we were able to perform pharmacokinetic functional analysis of a tumor, coregistration of MRI images with histological cross-sections, immunohistochemistry, laser capture microdissection, and genetic profiling of tumor heterogeneity based on pharmacokinetic parameters. …”
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166
Impact of Investment on Labour Productivity in Azerbaijan's Chemical and Petrochemical Industry
Published 2024-06-01“…The research employed a combination of analytical methods, including statistical analysis of data from the State Statistical Committee of Azerbaijan on labour productivity and investment in the chemical and petrochemical sectors. Functional analysis was used to examine the role of labour productivity, while systematic analysis explored the factors influencing productivity. …”
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167
Screening key genes for intracranial aneurysm rupture using LASSO regression and the SVM-RFE algorithm
Published 2025-01-01“…ROC analysis was conducted to further verify the diagnostic value of the key genes.ResultsA total of 334 DEGs were screened, including 175 upregulated genes and 159 downregulated genes. Further functional analysis suggested that the DEGs were enriched in inflammation and immune response pathways. …”
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168
Construction and evaluation of Brassica rapa orphan genes overexpression library
Published 2025-01-01“…The findings of this study provide a comprehensive overview of the roles of BrOGs, emphasizing their significance as a resource for identifying positive genes associated with species-specific characteristics and stress responses and offering a solid foundation for the functional analysis of BrOGs.…”
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169
Postrecruitment Function of Yeast Med6 Protein during the Transcriptional Activation by Mediator Complex
Published 2018-01-01“…Med6 protein (Med6p) is a hallmark component of evolutionarily conserved Mediator complexes, and the genuine role of Med6p in Mediator functions remains elusive. For the functional analysis of Saccharomyces cerevisiae Med6p (scMed6p), we generated a series of scMed6p mutants harboring a small internal deletion. …”
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170
Fat-tail allele-specific expression genes may affect fat deposition in tail of sheep.
Published 2024-01-01“…Using a rigorous computational pipeline, 115 differential ASE genes were identified, which were narrowed down to four genes (LPL, SOD3, TCP1 and LRPAP1) for being detected in at least two studies. Functional analysis revealed that the ASE genes were mainly involved in fat metabolism. …”
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171
Comprehensive Analysis of Breast Cancer Cell Lines: Genome-wide Insights from ChIP-seq Analysis
Published 2024-12-01“…Materials and Methods: Galaxy server (https://usegalaxy.org/) was used for complete ChIP-seq data analysis; different tools such as fast-quality control (QC), multi-QC, Bowtie2, model-based analysis of ChIP-sequencing, and ChIPseeker tools were used for motif enrichment and functional analysis. Motif analysis was done through the Multiple Expectation maximizations for Motif Elicitation database (https://meme-suite.org/meme/db/motifs). …”
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172
Gut microbiota in the association between obesity and kidney function decline: a metagenomics-based study in a rat model
Published 2024-12-01“…Metagenomics analysis revealed a notable rise in the prevalence of the Firmicutes phylum within the HFD group, primarily comprising the Rumenococcus genus. Functional analysis indicated that the gut microbiota in the HFD group primarily correlated with infectious diseases, signal transduction, and signaling molecules and interactions.Conclusions This study provides evidence that the consumption of a HFD induces modifications in the composition and functionality of the gut microbiome in rats, which may serve as a potential mechanism underlying the relationship between obesity and the progression of kidney function decline.…”
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173
Professional Network Community for Training Youth Workers: Conceptual Framework and Prerequisites for the Creation
Published 2022-01-01“…The purpose of the article is to describe the conceptual framework of a professional network community for training personnel for working with youth in the context of social, educational and youth policy and identify the prerequisites for its creation.In the course of the work, we used such methods as structural and functional analysis, system synthesis, modeling and an online survey. …”
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174
Topology Unveiled: A New Horizon for Economic and Financial Modeling
Published 2025-01-01“…By collecting abundant literature indexed in SCOPUS/WoS and other famous databases, with a qualitative analysis to classify and summarize it, we found that topological methods were introduced to modern economics when dealing with dynamic optimization, functional analysis, and convex programming problems, including famous applications such as uncovering equilibrium with fixed-point theorems in Walrasian economics. …”
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In silico Analysis of Human Endothelial Cell-specific Molecule 1 and Interleukin-6 Genetic Variants Involved in Coronary Artery Disease
Published 2024-12-01“…The functional impact of the SNPs was analyzed using Functional Analysis through Hidden Markov Models, Combined Annotation Dependent Depletion, Protein Analysis through Evolutionary Relationships, PredictSNP, Multivariate Analysis of Protein Polymorphism, Screening for Nonacceptable Polymorphisms, Predictor of human Deleterious Single-nucleotide Polymorphisms, and SNP functional annotation. …”
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176
Characterisation of Drosophila UbxCPTI000601 and hthCPTI000378 Protein Trap Lines
Published 2014-01-01“…Here, we describe expression and functional analysis to evaluate new Ubx and hth protein trap lines generated by the Cambridge Protein Trap project. …”
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177
Transcriptomic analysis reinforces the implication of spatacsin in neuroinflammation and neurodevelopment
Published 2025-01-01“…To elucidate its function, we conducted an extensive RNA sequencing (RNAseq) experiment and transcriptomic analysis in three distinct neural structures (cerebellum, cortex and hippocampus) and at three different ages (6 weeks, 4 months and 8 months) in both wild type and Spg11 −/− mice. Our functional analysis of differentially expressed genes (DEGs) and Gene Set Enrichment Analysis (GSEA) revealed dysregulation in pathways related to inflammation, RNA metabolism and neuronal and neurite development, factors frequently implicated in neurodegenerative disorders. …”
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178
Bioinformatics Analysis, Prokaryotic Expression and Biological Activity of Lysin from Vibrio parahaemolyticus Phage vB_VpP_1
Published 2025-02-01“…To study the in vitro cleavage effect of a recombinant lysin from bacteriophage vB_VpP_1 on Vibrio parahaemolyticus, the gp32 gene fragment of vB_VpP_1 was identified as a lysin gene according to the results of whole-genome sequencing (WGS) and functional analysis. The amino acid sequence and structure of gp32 were analyzed by various tools such as Expasy. …”
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179
A literary-historical analysis of Daniel 2: two powers in opposition
Published 2002-06-01“…Firstly, the structural investigation uses Propp’s model for a functional analysis of the text, followed by a semiotic analysis to identify the functions and qualifications in the text. …”
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FABP6 Expression Correlates with Immune Infiltration and Immunogenicity in Colorectal Cancer Cells
Published 2022-01-01“…Differentially expressed genes (DEGs) between “hot” and “cold” tumors were used for functional analysis. A prediction model was constructed to explore the survival of CRC patients treated with and without immunotherapy. …”
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