Metagenomics-based analysis of microbial community dynamics and flavor compound correlations during rice-flavor Baijiu brewing by Qun Li, Long Zhang, Long Zhang, Rui Li, Jie Tang, Bin Lin, Chunyu Qin, Wei Jiang, Longxu An, Fan Zhang, Xingxing Shi, Shengzhi Yang, Qiang Yang, Shenxi Chen

“…Six genera, Lichtheimia, Kluyveromyces, Lacticaseibacillus, Lactobacillus, Limosilactobacillus, and Schleiferilactobacillus were identified as primary contributors to flavor production during fermentation. Functional analysis revealed that microbial metabolism in fermented mash primarily involved amino acid and carbohydrate metabolism, with glycoside hydrolases (GHs) and glycosyl transferases (GTs) serving as key carbohydrate-active enzymes. …”
Get full text

Identification of the first plant caffeoyl-quinate esterases in Cichorium intybus by Antoine Mallavergne, David Mathiron, Roland Molinié, Jean-Louis Hilbert, David Gagneul

“…Biochemical characterization and functional analysis in tobacco revealed that both enzymes can hydrolyze 5-CQA and 3,5-DiCQA to release caffeic acid (CA) both in vitro and in planta. …”
Get full text

Enhancing Pea Flour Characteristics Through Radio Frequency Heating: Effects on Composition, Flavour, Anti‐Nutrients and Functionality by Praiya Asavajaru, Pabitra Chandra Das, Aarti Bhagwat, Darrin Klassen, Li Liu, Peng Gao, Yuping Lu, Prem Prakash Das, Nandhakishore Rajagopalan

“…Volatolomics studies revealed the generation of a number of new pyrazine class of volatile flavour compounds in situ, only in the RF treatment at the higher temperature of 115°C. Techno‐functional analysis of dehulled milled flours prepared from RF‐treated seeds showed an increase in water holding capacity, while the oil absorption capacity, foaming and emulsion properties decreased compared to untreated control. …”
Get full text

Inertial measurement units to evaluate the efficacity of Equino Varus Foot surgery in post stroke hemiparetic patients: a feasibility study by Nicolas de l’Escalopier, Cyril Voisard, Sylvain Jung, Mona Michaud, Albane Moreau, Nicolas Vayatis, Philippe Denormandie, Alix Verrando, Claire Verdaguer, Alain Moussu, Aliénor Jequier, Christophe Duret, Laurence Mailhan, Laure Gatin, Laurent Oudre, Damien Ricard

“…The follow-up duration was 6 months and included a functional analysis using Goal Attainment Scaling (GAS) and a Gait analysis using an innovative Multidimensional Gait Evaluation using IMU: the semiogram. …”
Get full text

Amyloid-induced mitochondrial network disruption in neurons monitored by STED super-resolution imaging by Iuliia Golovynska, Qinglin Chen, Yurii V. Stepanov, Danying Lin, Junle Qu

“…In the study, mitochondrial network analysis is performed using stimulated emission depletion (STED) super-resolution fluorescence microscopy to examine alterations in neurons exposed to Aβ in vitro.MethodsA detailed analysis of mitochondrial network in healthy neurons and those exposed to Aβ is performed using STED compared to conventional laser-scanning confocal fluorescence microscopy. The functional analysis is applied to mitochondrial volume, surface area, branch length, diameter, junctions, and endpoints. …”
Get full text

Exploring program-cell death patterns to predict prognosis and sensitivity of cervical cancer immunotherapy via multi-omics analysis and clinical samples by Chunhong Pang, Xianfeng Long, Yongjin Luo, Ying Luo

“…Real-time quantitative PCR (qRT-PCR) and immunohistochemistry were used to verify the expression of the model genes. Finally, functional analysis of low- and high-risk groups based on the median risk score was performed, including immune infiltration, genomic mutations, tumor mutational burden (TMB), and drug sensitivity. …”
Get full text

DEVELOPMENT OF THE CONCEPT OF SUBSIDIARY LIABILITY AS A TOOL TO INCREASE THE EFFECTIVENESS OF THE INSTITUTION OF BANKRUPTCY AND ENSURE THE ECONOMIC SECURITY OF THE COUNTRY by V. N. Alferov, M. M. Korigova

“…To achieve the goal, the following problems are solved in the article: the definition of theoretical and practical aspects, the generalization of processes for the formation and development of the concept of subsidiary liability of an unscrupulous controlling the debtor’s persons; the analysis of practical problems of realization of the concept of subsidiary responsibility of an unscrupulous controlling the debtor’s persons; a study of the Russian and foreign practice of implementing the institution of bankruptcy and subsidiary liability unscrupulous controlling the debtor’s persons; the formation of proposals on the development of the concept of subsidiary liability of an unscrupulous debtor controlling the debtor as a tool to increase the eficiency of the institution of bankruptcy and ensure economic security.Methods: methods the article is based on a systematic approach to the definition and formation of the concept of subsidiary responsibility, theoretical, economic and functional analysis of the complex interaction of the main participants of the institution of bankruptcy and the impact of their activities on the economic security of the country.Results: the increase in the number of illegal actions in bankruptcy cases led to the need in the last decade to strengthen the economic (subsidiary) responsibility of the debtor controlling the debtor. …”
Get full text

A cross-tissue transcriptome-wide association study identifies WDPCP as a potential susceptibility gene for coronary atherosclerosis by Xinyue Hu, Guanglei Chen, Xiaofang Yang, Jin Cui, Ning Zhang

“…While genome-wide association studies (GWAS) have pinpointed many risk loci, over 75 % are in non-coding regions, complicating functional analysis and understanding gene-disease mechanisms. …”
Get full text

ADMINISTRATIVE AND ORGANIZATIONAL ASPECTS OF FUNCTIONING OF THE SYSTEM OF AVAILABILITY NARCOTIC AND PSYCHOTROPIC MEDICINAL PREPARATIONS FOR PATIENTS WHO NEED THEM by I. A. Kaminskaya, I. N. Tyurenkov

“…The study employed the methods of content analysis, logical and functional analysis, etc.Results and Discussion. The system of narcotic and psychotropic drug (NPD) availability for patients who need them is currently going through reforms which have been conditioned by low accessibilty of these drugs when used for medical purposes. …”
Get full text

Exploring RNA cargo in extracellular vesicles for pleural mesothelioma detection by Agnieszka Kraft, Michaela B. Kirschner, Vanessa Orlowski, Manuel Ronner, Caroline Bodmer, Valentina Boeva, Isabelle Opitz, Mayura Meerang

“…Interestingly, 25 of them were the sarcomatoid and epithelioid marker genes. Finally, functional analysis revealed that the PM-EV RNA cargo was associated with Epithelial-Mesenchymal transition, glycolysis, and hypoxia. …”
Get full text

Improving the efficiency of the formation of professional competencies Masters in “Information Security” based on the use o CASE-technologies by A. V. Gavrilov, V. A. Sizov

“…Modern approaches to the formation of the register of enterprise information resources, according to the authors, do not offer an effective method of identifying resources and estimating their value.This paper considers an approach based on the use of structural and functional analysis methods and CASE-technologies in the formation of a register of information resources of the enterprise in the training of masters in the direction of “Information Security”. …”
Get full text

Deciphering the role of miR-71 in Echinococcus multilocularis early development in vitro. by Matías Gastón Pérez, Markus Spiliotis, Natalia Rego, Natalia Macchiaroli, Laura Kamenetzky, Nancy Holroyd, Marcela Alejandra Cucher, Klaus Brehm, Mara Cecilia Rosenzvit

“…To develop methodology for functional analysis of miRNAs in tapeworms, we performed miRNA knockdown experiments in primary cell cultures of Echinococcus multilocularis, which mimic the development of metacestode vesicles from parasite stem cells in vitro. …”
Get full text

The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation. by Federico Innocenti, Kouros Owzar, Chen Jiang, Amy S Etheridge, Raluca Gordân, Alexander B Sibley, Flora Mulkey, Donna Niedzwiecki, Dylan Glubb, Nicole Neel, Mark S Talamonti, David J Bentrem, Eric Seiser, Jen Jen Yeh, Katherine Van Loon, Howard McLeod, Mark J Ratain, Hedy L Kindler, Alan P Venook, Yusuke Nakamura, Michiaki Kubo, Gloria M Petersen, William R Bamlet, Robert R McWilliams

“…We aim also to support these findings with in vitro functional analysis.<h4>Patients and methods</h4>Genome-wide screens of germline DNA in two independent cohorts of pancreatic cancer patients (from the Cancer and Leukemia Group B (CALGB) 80303 and the Mayo Clinic) were used to select new genes associated with OS. …”
Get full text

Structural changes in the mechanism for managing the sustainable development of an organization by V. V. Kabanov

“…The study used methods of system, structural and functional analysis, and also a method of a grouping and methodical recommendations for the formation of program goals for sustainable development and the construction of a business model for sustainability. …”
Get full text

The influence of vaginal microbiota on ewe fertility: a metagenomic and functional genomic approach by Edgar L. Reinoso-Peláez, María Saura, Carmen González, Manuel Ramón, Jorge H. Calvo, Magdalena Serrano

“…The metagenomic approach used here enabled not only comprehensive taxonomic classification but also detailed functional analysis, providing deeper insights into the microbiome’s role in reproductive outcomes. …”
Get full text

The rise of online banks in Italy “WIDIBA Bank” Case Study by Alessio Faccia, Narcisa Roxana Moşteanu, Luigi Pio Leonardo Cavaliere, Gabriele De Santis

“…The theoretical researches were carried out in the work, in particular, in the following directions: definition of strategic actions of bank establishment according to a time lag of functioning; analysis of the budget of the banking institution (net profitability, interest margin, operating and administrative expenses, etc.); analysis of the income statement of the bank (the ratio of net profit and loss, interest margin and brokerage margin); work with financial report or balance sheet data on the structure of assets, liabilities and investments, retained earnings; study of trend dynamics of cash flows (operational, financial, investment and free cash flows). …”
Get full text

Phenome-wide association study and functional annotation of hemoglobin A1c-associated variants in African populations. by Chisom Soremekun, Oyesola Ojewunmi, Amarachukwu Nwagbata, Homa Bazireh, Sapna Sharma, Daudi Jjingo, David Patrick Kateete, Oyekanmi Nash, Harald Grallert, Chiara Batini, Annette Peters, Segun Fatumo

“…We also performed a functional analysis using the functional mapping and annotation (FUMA) tool. …”
Get full text

Effects of Solid-state Fermentation of Lactic Acid Bacteria on the Physical, Structural and Functional Properties of Soluble Dietary Fiber from Highland Barley Bran by Xuzhao WEI, Huicui LIU, Yuchen YANG, Xiaohai CAO

“…The results of functional analysis showed that SDF from highland barley bran after fermentation had strong lipid lowering activity, antioxidant ability and inhibition ability of sugar-digesting enzyme. …”
Get full text

Foundations of radar synthesis theory of phantom objects formation in SAR images by Volodymyr Pavlikov, Simeon Zhyla, Pavlo Pozdniakov, Denys Kolesnikov, Hlib Cherepnin, Olexandr Shmatko, Oleksii Odokiienko, Pavlo Malashta, Eduard Tserne

“…The solution to these tasks is based on the methods of the remote sensing system synthesis theory, radiophysics, coherent image formation, functional analysis, synthesis, and processing of spatiotemporal signals. …”
Get full text

Modeling and computational study of cancer treatment with radiotherapy using real data. by Parvaiz Ahmad Naik, Muhammad Farman, Saba Jamil, Muhammad Umer Saleem, Kottakkaran Sooppy Nisar, Zhengxin Huang

“…The model acquires stability strength through Lyapunov functions analysis to create a solid scientific foundation in oncology research.…”
Get full text