Strategic model for integrating biogas a framework for sustainable energy integration in agro-industries by Ahmad Nahwani, Soeprijanto Soeprijanto, Erwin Widodo

“…In this study, the technique of the system in functional analysis is shown systematically to translate various energy requirements in the factory as criteria for performance and functional design to be integrated, optimized, and energy efficient. …”
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Cigarette Smoke Exposure Inhibits Bacterial Killing via TFEB-Mediated Autophagy Impairment and Resulting Phagocytosis Defect by Garrett Pehote, Manish Bodas, Kathryn Brucia, Neeraj Vij

“…Briefly, RAW cells were treated with cigarette smoke extract (CSE), chloroquine (autophagy inhibitor), TFEB-shRNA, CFTR(inh)-172, and/or fisetin prior to bacterial infection for functional analysis. Results. Bacterial clearance of PA01-GFP was significantly impaired while its survival was promoted by CSE (p<0.01), autophagy inhibition (p<0.05; p<0.01), TFEB knockdown (p<0.01; p<0.001), and inhibition of CFTR function (p<0.001; p<0.01) in comparison to the control group(s) that was significantly recovered by autophagy-inducing antioxidant drug, fisetin, treatment (p<0.05; p<0.01; and p<0.001). …”
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Identification of the Active Compound of Liu Wei Di Huang Wan for Treatment of Gestational Diabetes Mellitus via Network Pharmacology and Molecular Docking by Yunqi Xiong, Qiutong Li, Xiuhui Chen, Ting Zhu, Qitian Lu, Guojing Jiang

“…Furthermore, gene functional analysis and protein–protein interaction (PPI) network construction were applied to investigate the function of potential targets and to evaluate hub genes. …”
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In silico Analysis of Human Endothelial Cell-specific Molecule 1 and Interleukin-6 Genetic Variants Involved in Coronary Artery Disease by Vineet Kulkarni, Sukanya Shetty, Roopa Bhandary, Yanglem Mary

“…The functional impact of the SNPs was analyzed using Functional Analysis through Hidden Markov Models, Combined Annotation Dependent Depletion, Protein Analysis through Evolutionary Relationships, PredictSNP, Multivariate Analysis of Protein Polymorphism, Screening for Nonacceptable Polymorphisms, Predictor of human Deleterious Single-nucleotide Polymorphisms, and SNP functional annotation. …”
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Identification and characterization of nine PAT1 genes subfamily in Medicago edgeworthii by Gaoping Tang, Tingting Ni, García-Caparrós Pedro, Li-Hua Meng, Xudong Sun

“…Additionally, we observed that members of the PAT1 subfamily were expressed in roots, stems, and leaves, indicating their broad involvement in the development of various tissues in M. edgeworthii. Furthermore, functional analysis indicated that PAT1 subfamily proteins in M. edgeworthii activated the expression of MeDOF3.4 gene, indicating that PAT1 subfamily proteins may be associated with the promotion of cell proliferation and graft fusion. …”
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Calculation of the main operational characteristics of a tethered high-altitude ship-based system by I. I. Dawlyud

“…The study used methods of systemic and functional analysis of tethered system parameters, as well as methods and models of the theory of relations and measurement.Results. …”
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METHODS OF APPROXIMATION OF SUMMABLE FUNCTIONS ON THE BASIS OF THE INTEGRAL OF STIELTJES WITH RESPECT TO APPLIED ANALYSIS by Igor Eduardovich Naats, Elena Pavlovna Yartseva

“…Difficulties associated with the use of conventional derivatives for the analysis of such functional dependencies require the development of such methods of functional analysis which would operirovat-whether the so-called generalized derivatives (also operators of generalized differentiation). …”
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RASGRP2 Suppresses Apoptosis via Inhibition of ROS Production in Vascular Endothelial Cells by Takuma Sato, Jun-ichi Takino, Kentaro Nagamine, Kazuto Nishio, Takamitsu Hori

“…Therefore, we performed functional analysis of RASGRP2 using immortalized HUVEC (TERT HUVEC). …”
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Differences in the proteomic profiles of the eutopic endometrium in patients with internal and external adenomyosis. by Marta Valdés-Bango, Mikel Azkargorta, Meritxell Gracia, Cristina Ros, Mariona Rius, María-Angeles Martínez-Zamora, Cristian De Guirior, Lara Quintas, Félix Elortza, Francisco Carmona

“…Gene Ontology and Ingenuity Pathway Analysis were employed for further functional analysis and network generation. The proteomic profiles of the eutopic endometrium differed significantly among women with internal adenomyosis, external adenomyosis, and controls. …”
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HarmGR13 mediates myo-inositol taste perception in Helicoverpa armigera larvae. by Yu-Sheng Tan, Bao-Tong Mo, Guo-Cheng Li, Yu-Ruo Guo, Jian-Zhen Zhang, Chen-Zhu Wang

“…Behavioral assays confirmed that larvae of HarmGR13 homozygous mutant lost the feeding preference to myo-inositol which the wild-type larvae had. Further functional analysis with Xenopus oocytes expressing system and two-electrode voltage-clamping demonstrated that myo-inositol and ribose specifically induced concentration-dependent currents in HarmGR13-expressing oocytes. …”
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Unraveling the pathogenomics of Rhizoctonia solani infecting proso millet (Panicum miliaceum L.): genomic perspective on ruthless virulence and adaptive evolution by Prasanna S. Koti, T. S. S. K. Patro, K. B. Palanna, B. Jeevan, Porapu Prasanth, G. V. Ramesh, N. Anuradha, Y. Sandhya Rani, Ungata Triveni, K. Lavanya Devi, T. Tharana Poonacha, Farooq Khan, Boda Praveen, M. Divya, D. Sabina Mary, V. Prasanna Kumari, T. E. Nagaraja, R. Madhusudhana, C. Tara Satyavathi

“…Notably, variations were observed in important secretory proteins, such as multiple base deletions in MFS proteins across strains infecting proso millet, rice, and sugar beet.DiscussionFunctional analysis of the VAP-1 genome has unveiled a wealth of insights, though we have only begun to scratch the surface. …”
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Pharmacologically inducing regenerative cardiac cells by small molecule drugs by Wei Zhou, Kezhang He, Chiyin Wang, Pengqi Wang, Dan Wang, Bowen Wang, Han Geng, Hong Lian, Tianhua Ma, Yu Nie, Sheng Ding

“…In this study, we demonstrate that a two-compound combination, CHIR99021 and A-485 (2C), effectively induces RCCs from human embryonic stem cell-derived TNNT2+ CMs in vitro, as evidenced by lineage tracing experiments. Functional analysis shows that these RCCs express a broad spectrum of cardiogenesis genes and have the potential to differentiate into functional CMs, endothelial cells, and smooth muscle cells. …”
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Screening and Evaluation of Deleterious SNPs in APOE Gene of Alzheimer’s Disease by Tariq Ahmad Masoodi, Sulaiman A. Al Shammari, May N. Al-Muammar, Adel A. Alhamdan

“…FASTSNP was used for functional analysis and estimation of risk score. The functional impact on the APOE protein was evaluated by using Swiss PDB viewer and NOMAD-Ref server. …”
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Characteristics and function of the gut microbiota in patients with IgA nephropathy via metagenomic sequencing technology by Yang Deng, Zhiqiang Nong, Meiju Wei, Yuanshan Xu, Yuzhen Luo, Xiaohua Li, Ruobei Zhao, Zhenhua Yang, Ling Pan

“…The characteristic microorganisms in the IgAN group with abnormal renal function were identified as Enterococcaceae, Moraxella, Moraxella, and Acinetobacter. KEGG functional analysis demonstrated that the functional pathways of the microbiota that differed between IgAN patients and healthy controls were related primarily to bile acid metabolism.Conclusions The status of the gut microbiota is closely associated not only with the onset of IgAN but also with the renal function of IgAN patients. …”
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Strategy for nitrogen fertilizer substitution: Co-composting of agricultural waste to regulate vegetable quality and rhizosphere microorganisms by Xiaoning Liu, Qiang Wang, Yupeng Wang, Shizhou Shen, Yihong Ge, Ke Pan, Xiaobo Guo, Yunhui Lei, Yi Gao

“…Proteobacteria and Ascomycota are important microbial families that affect the growth and quality indicators of pakchoi, respectively. Functional analysis showed that the compost mainly regulated the growth and quality of pakchoi by upregulating the relative abundance of functional genes related to carbohydrate metabolism, lipid metabolism, and exogenous biodegradation and metabolism, as well as by increasing the abundance of symbiotic and saprotrophic fungi while decreasing that of pathotrophic fungi. …”
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Deep learning-guided structural analysis of a novel bacteriophage KPP105 against multidrug-resistant Klebsiella pneumoniae by Seyoung Ko, Jaehyung Kim, Jae-Hyun Cho, Youngju Kim, Donghyuk Kim

“…Structure-based functional analysis provided comprehensive insights into cell wall degradation with various peptidoglycan fragments. …”
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The Impact of Fucoidan Extracts on Heat-Stress-Induced Loss of In Vitro Fast-Twitch Muscle Function in Mice by Samantha T. C. Kucewicz, Stefan Piantella, Jarrod E. Church, Caroline J. Taylor, Chris van der Poel

“…Subsequently, the in vitro muscle function of the fast-twitch extensor digitorum longus (EDL) was assessed at either 25 °C (control) or 43 °C (heat stress). Functional analysis was complemented with gene analysis and the C2C12 myoblast heat-stress assay. …”
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Reclassification of Two MLH1 Variants of Uncertain Significance Utilizing Clinical and Functional Data by Jane Hübertz Frederiksen, Ulf Birkedal, Sarah Bachmann, Elisabeth Victoria Eliesen, Lene Juel Rasmussen, Katja Venborg Pedersen, Lana Al‐Zehhawi, Susanne E. Boonen, Lotte Krogh, Karina Rønlund, Lise Graversen, Jannie Assenholt, Kjeld Schmiegelow, Karin Wadt, Anne‐Marie Gerdes, Thomas v. O. Hansen

“…Methods To reclassify the variants we collected clinical data, initiated tumor and co‐segregation analysis, and performed RNA splicing analysis, subcellular localization, and protein stability studies. Results The functional analysis revealed that the c.696_698del, p.(Cys233del) variant had an effect at the RNA level, on subcellular localization, and on protein stability, while the c.1919C > G, p.…”
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Integrating Near-Infrared Spectroscopy and Proteomics for Semen Quality Biosensing by Notsile H. Dlamini, Mariana Santos-Rivera, Carrie K. Vance-Kouba, Olga Pechanova, Tibor Pechan, Jean M. Feugang

“…Nexin-1 and seminal plasma protein pB1 were upregulated in Passed samples, while LGALS3BP was downregulated. The functional analysis highlighted pathways associated with single fertilization, filament organization, and glutathione metabolism in Passed samples. …”
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Salivary Proteome Insights: Evaluation of Saliva Preparation Methods in Mucopolysaccharidoses Research by Maria-Andreea Soporan, Ioana-Ecaterina Pralea, Maria Iacobescu, Radu Cristian Moldovan, Camelia Alkhzouz, Diana Miclea, Cristina-Adela Iuga

“…Both methods showed high digestion efficiency, particularly with Rapigest buffer, achieving over 80% full cleavage across conditions. Functional analysis revealed broad similarities, with protocol-specific impacts on protein classes and cellular components. …”
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