Suggested Topics within your search.
Suggested Topics within your search.
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1041
Yeast for virus research
Published 2017-09-01“…Potential applications of using yeasts as hosts to carry out functional analysis of small viral genome and to develop high throughput drug screening platform for the discovery of antiviral drugs are presented.…”
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1042
Digitalization in public service: effectiveness analysis of information and communication platforms of government bodies in providing services to the population
Published 2025-07-01“…The relevance is substantiated by the fact that ICPs are becoming an integral part of management processes, allowing not only to simplify citizens' access to state and municipal services, but also to ensure transparency of decision-making, prompt feedback and strengthening trust in government institutions.The methods and materials used in the research are structural and functional analysis, content analysis – a study of Internet sites of government bodies at various levels, as well as a comparison method when comparing them according to various criteria.The Research results. …”
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1043
Construction of the Historical and Cultural Media Landscape in Regional Media
Published 2024-10-01“…The following research methods were used in the work: general scientific methods of observing the material and describing it, the method of historicism, the method of content analysis, the method of discourse analysis, the cultural method, the method of functional analysis. In the course of the study, the content of the concept “cultural space of the city” was outlined, the specifics of the media space and media images as factors of modern cultural identification were considered; the functions of the media are highlighted, with the help of which the cultural “face” of the region is formed. …”
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1044
Functional genomic approach to the study of biodiversitywithin Trichoderma
Published 2004-07-01“…The selected clone sequences were completed and cloned in appropriate vectors to initiate functional analysis by means of expression studies in homologous and heterologous systems.…”
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1045
MED8 is related to tumor immunity and has predictive value in the prognosis and treatment of glioma
Published 2025-07-01“…Cox regression analysis and survival analysis revealed that MED8 is an independent prognostic factor in gliomas, and patients with high expression of MED8 have a poor prognosis. Functional analysis revealed that there was a close relationship between MED8 expression and tumor immune features, and there was a correlation between MED8 expression and tumor-associated macrophages (TAMs) levels. …”
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1046
Genome-wide classification and evolutionary and expression analyses of citrus MYB transcription factor families in sweet orange.
Published 2014-01-01“…These results provide a useful reference for the selection of candidate MYB genes for cloning and further functional analysis forcitrus.…”
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1047
Identification of Genes Predicting Poor Response of Trastuzumab in Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer
Published 2022-01-01“…Fifty upregulated overlapping DEGs were identified by analyzing two trastuzumab resistance-related GEO databases. Functional analysis picked out ten hub genes enriched in mitochondrial function and metabolism pathways: ASCL1, CPT2, DLD, ELVOL7, GAMT, NQO1, SLC23A1, SPR, UQCRB, and UQCRQ. …”
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1048
An efficient method for transgenic callus induction from Vitis amurensis petiole.
Published 2017-01-01“…This efficient transformation system will facilitate the functional analysis of agronomic characteristics and related genes not only in V. amurensis but also in other grapevine species.…”
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1049
IGF1 and NRG1 Enhance Proliferation, Metabolic Maturity, and the Force-Frequency Response in hESC-Derived Engineered Cardiac Tissues
Published 2017-01-01“…Developmentally related processes were identified in engineered tissues as IGF1 increased hESC-cardiomyocyte proliferation 3-fold over untreated controls and NRG1 stimulated oxidative phosphorylation and promoted a positive force-frequency relationship in tissues up to 3 Hz. hESC-cardiomyocyte area increased significantly with NRG1 and IGF1 + NRG1 treatment in 2D culture and gene expression data suggested increased cardiac contractile components in engineered tissues, indicating the need for functional analysis in a 3D platform to accurately characterize engineered cardiac tissue response to biochemical stimulation. …”
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1050
Transcriptomic characterization of cancer-testis antigens identifies MAGEA3 as a driver of tumor progression in hepatocellular carcinoma.
Published 2021-06-01“…Further analysis of CTAs in larger patient cohorts revealed high CTA expression related to worse overall survival and several other markers of poor prognosis. Functional analysis of MAGEA3 was performed in human HCC cell lines by gene silencing and in a genetic mouse model by overexpression of MAGEA3 in the liver. …”
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1051
Effects of one-week intake of different edible oils on the urinary proteome of rats
Published 2025-07-01“…Differentially expressed proteins and differential post-translational modifications in the urinary proteome were screened for functional analysis.ResultsAll edible oil groups exhibited significant alterations in metabolic pathways, with distinct proteomic profiles observed across oil types, but there were few common differentially expressed proteins among different groups. …”
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1052
Reliability Analysis and Numerical Simulation of Industrial Robot Drive System with Vacation
Published 2025-04-01“…Using the supplementary variable method, a mathematical model of the system is constructed and formulated within an appropriate Banach space, leading to the derivation of the system’s abstract development equation. Leveraging functional analysis and the <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mi>C</mi><mn>0</mn></msub></semantics></math></inline-formula>-semigroup theory of bounded operators, the study examines the system’s adaptability, stability, and key reliability indices. …”
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1053
OPTIMIZATION OF INFRASTRUCTURE PROJECT PRODUCT PARAMETERS
Published 2020-12-01“…The following methods are used: system analysis, functional analysis, operations research. Results: it was found that the parameters of the product of infrastructure projects, on the one hand, ensure its commercial relevance, on the other hand, they determine the characteristics of the project (cost, risks, life cycle duration, etc.), which forms a complex system of requirements and restrictions for product parameters. …”
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1054
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1055
Effect of <i>Brassica rapa</i> L. Polysaccharide on Lewis Lung Cancer Mice by Inflammatory Regulation and Gut Microbiota Modulation
Published 2024-11-01“…A correlation analysis showed significant correlations among the gut microbiota, SCFAs, inflammatory factors, and tight junction proteins. A functional analysis indicated that BP promoted amino acid metabolism and fatty acid metabolism. …”
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1056
IMPACT OF THE STATE ON THE DEVELOPMENT OF INFRASTRUCTURE AN EXPOSITORY ANALYSIS OF ROAD, ELECTRICITY AND HEALTH
Published 2025-04-01“…Our methods of data collection was documentary which enabled us to use secondary sources of data like the documentary materials.The study was predicated on the structural functional analysis or structural functionalism as a theoretical framework. …”
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1057
The Taxonomic and Functional Diversity of Leaf-Litter Dwelling Ants in the Tropical Dry Forest of the Colombian Caribbean
Published 2024-11-01“…Our results highlight the importance of integrating a functional analysis with the taxonomic assessment of ants as an important contribution to understanding the organization and dynamics of this community of insects that inhabit the tropical dry forest.…”
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1058
Alternative splicing and nonsense-mediated RNA decay contribute to the regulation of SHOX expression.
Published 2011-03-01“…A bioinformatical analysis of the three novel 3'UTR exons yielded insights into the putative role of the different 3'UTRs as targets for miRNA binding. Functional analysis revealed that inclusion of exon 2a leads to nonsense-mediated RNA decay altering SHOX expression in a tissue and time specific manner. …”
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1059
The Role of Digitalization in Data-Driven Decision Making in Supply Chain Management
Published 2025-06-01“…Using structural-functional analysis and the case study method, the study examines management practices synthesizes a comprehensive approach to exploring the interrelation between technological and managerial innovations during the implementation of digital platforms. …”
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1060